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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: SAPCD1-AS1 (CAeditome ID:104413891)

Gene summary for SAPCD1-AS1

check button Gene summary
Gene informationGene symbol

SAPCD1-AS1

Gene ID

104413891

Gene nameSAPCD1 antisense RNA 1
SynonymsC6orf26-AS1
Cytomap

6p21.33

Type of genencRNA
DescriptionC6orf26 antisense RNA 1 (non-protein coding)SAPCD1 antisense RNA 1 (non-protein coding)XXbac-BPG32J3.18
Modification date20210518
UniProtAcc

.

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for SAPCD1-AS1

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000235663.1
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_468886(31764938, -), CAediting_468887(31764957, -), CAediting_468888(31764982, -), CAediting_468889(31764990, -), CAediting_468890(31764993, -), CAediting_468891(31765005, -), CAediting_468892(31765009, -), CAediting_468893(31765025, -), CAediting_468894(31765030, -), CAediting_468895(31765035, -), CAediting_468896(31765041, -), CAediting_468897(31765044, -), CAediting_468898(31765048, -), CAediting_468899(31765065, -), CAediting_468900(31765070, -), CAediting_468901(31765071, -), CAediting_468902(31765079, -), CAediting_468903(31765087, -), CAediting_468904(31765181, -), CAediting_468905(31765193, -), CAediting_468906(31765194, -), CAediting_468907(31765317, -), CAediting_468908(31765352, -), CAediting_468909(31765356, -), CAediting_468910(31765357, -), CAediting_468911(31765376, -), CAediting_468912(31765377, -), CAediting_468913(31765393, -), CAediting_468914(31765406, -), CAediting_468915(31765420, -), CAediting_468916(31765430, -), CAediting_468917(31765436, -),

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RNA editing positional annotations for SAPCD1-AS1 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_468886chr6_31764938_-ncRNA_intronic
CAediting_468887chr6_31764957_-ncRNA_intronic
CAediting_468888chr6_31764982_-ncRNA_intronic
CAediting_468889chr6_31764990_-ncRNA_intronic
CAediting_468890chr6_31764993_-ncRNA_intronic
CAediting_468891chr6_31765005_-ncRNA_intronic
CAediting_468892chr6_31765009_-ncRNA_intronic
CAediting_468893chr6_31765025_-ncRNA_intronic
CAediting_468894chr6_31765030_-ncRNA_intronic
CAediting_468895chr6_31765035_-ncRNA_intronic
CAediting_468896chr6_31765041_-ncRNA_intronic
CAediting_468897chr6_31765044_-ncRNA_intronic
CAediting_468898chr6_31765048_-ncRNA_intronic
CAediting_468899chr6_31765065_-ncRNA_intronic
CAediting_468900chr6_31765070_-ncRNA_intronic
CAediting_468901chr6_31765071_-ncRNA_intronic
CAediting_468902chr6_31765079_-ncRNA_intronic
CAediting_468903chr6_31765087_-ncRNA_intronic
CAediting_468904chr6_31765181_-ncRNA_intronic
CAediting_468905chr6_31765193_-ncRNA_intronic
CAediting_468906chr6_31765194_-ncRNA_intronic
CAediting_468907chr6_31765317_-ncRNA_intronic
CAediting_468908chr6_31765352_-ncRNA_intronic
CAediting_468909chr6_31765356_-ncRNA_intronic
CAediting_468910chr6_31765357_-ncRNA_intronic
CAediting_468911chr6_31765376_-ncRNA_intronic
CAediting_468912chr6_31765377_-ncRNA_intronic
CAediting_468913chr6_31765393_-ncRNA_intronic
CAediting_468914chr6_31765406_-ncRNA_intronic
CAediting_468915chr6_31765420_-ncRNA_intronic
CAediting_468916chr6_31765430_-ncRNA_intronic
CAediting_468917chr6_31765436_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_468886chr6_31764938_-SINEAluAluJb
CAediting_468887chr6_31764957_-SINEAluAluJb
CAediting_468888chr6_31764982_-SINEAluAluJb
CAediting_468889chr6_31764990_-SINEAluAluJb
CAediting_468890chr6_31764993_-SINEAluAluJb
CAediting_468891chr6_31765005_-SINEAluAluJb
CAediting_468892chr6_31765009_-SINEAluAluJb
CAediting_468893chr6_31765025_-SINEAluAluJb
CAediting_468894chr6_31765030_-SINEAluAluJb
CAediting_468895chr6_31765035_-SINEAluAluJb
CAediting_468896chr6_31765041_-SINEAluAluJb
CAediting_468897chr6_31765044_-SINEAluAluJb
CAediting_468898chr6_31765048_-SINEAluAluJb
CAediting_468899chr6_31765065_-SINEAluAluJb
CAediting_468900chr6_31765070_-SINEAluAluJb
CAediting_468901chr6_31765071_-SINEAluAluJb
CAediting_468902chr6_31765079_-SINEAluAluJb
CAediting_468903chr6_31765087_-SINEAluAluJb
CAediting_468904chr6_31765181_-SINEAluAluSq
CAediting_468905chr6_31765193_-SINEAluAluSq
CAediting_468906chr6_31765194_-SINEAluAluSq
CAediting_468907chr6_31765317_-SINEAluAluSq
CAediting_468908chr6_31765352_-SINEAluAluSq
CAediting_468909chr6_31765356_-SINEAluAluSq
CAediting_468910chr6_31765357_-SINEAluAluSq
CAediting_468911chr6_31765376_-SINEAluAluSq
CAediting_468912chr6_31765377_-SINEAluAluSq
CAediting_468913chr6_31765393_-SINEAluAluSq
CAediting_468914chr6_31765406_-SINEAluAluSq
CAediting_468915chr6_31765420_-SINEAluAluSq
CAediting_468916chr6_31765430_-SINEAluAluSq
CAediting_468917chr6_31765436_-SINEAluAluSq

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RNA A-to-I editing events in the alternative splicing sites for SAPCD1-AS1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000235663.1.SAPCD1-AS1.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000235663.1.SAPCD1-AS1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SAPCD1-AS1

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
KIRP.CAediting_468890.ENSG00000235663.SAPCD1-AS1.png
Soverview

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Protein coding region RNA A-to-I editings for SAPCD1-AS1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for SAPCD1-AS1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_748296chr10_51299626_+ENSG00000235663.1ENST00000419679.1hsa-miR-605-3p31764371317643777mer-m83176437031764391140-16.95
CAediting_1524209chrX_134546392_-ENSG00000235663.1ENST00000419679.1hsa-miR-503-5p31764446317644516mer3176444531764468144-23.55

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_468389chr6_31355314_-ENSG00000235663.1ENST00000419679.1hsa-miR-6891-5p31764368317643747mer-m83176436731764384150-21.1

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SAPCD1-AS1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for SAPCD1-AS1

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
BRCACAediting_468888chr6_31764982_-0.03619856965202260.245634783814659....
OVCAediting_468888chr6_31764982_-0.03873798996448850.20810007558462....
LGGCAediting_468890chr6_31764993_-..3.62438263616341e-050.434549522446863..
BRCACAediting_468890chr6_31764993_-0.0239386186694170.149527299410867....
LIHCCAediting_468890chr6_31764993_-0.003625702183743640.240936038145252....
CESCCAediting_468890chr6_31764993_-0.0001234957546680520.498815346394097....
LUADCAediting_468890chr6_31764993_-8.53146515137693e-090.343820050152494....
LUSCCAediting_468890chr6_31764993_-..0.007486793954370850.314862624577436..
STADCAediting_468890chr6_31764993_-0.01824431187871060.2000040012553890.00232532652978810.256276155062529..
THCACAediting_468890chr6_31764993_-3.21030713765997e-050.200936711354610.002220741422267350.148523804379889..
KIRCCAediting_468890chr6_31764993_-..0.002019614647116290.179358641845274..
UCECCAediting_468890chr6_31764993_-2.07908000699649e-060.411313777114888....
KIRPCAediting_468890chr6_31764993_-..3.60480592992291e-340.680837815907253..
OVCAediting_468890chr6_31764993_-0.0004601921327087120.228169123011173....
PAADCAediting_468890chr6_31764993_-0.02281136928171190.214053896430011....
PCPGCAediting_468890chr6_31764993_-..7.67199625739371e-070.373661227855872..
LUADCAediting_468891chr6_31765005_-0.01930526334780030.262768280317372....
THCACAediting_468891chr6_31765005_-0.0005652931237136370.280083439379855....
KIRCCAediting_468891chr6_31765005_-0.01796469068744220.274449773367161....
PCPGCAediting_468891chr6_31765005_-0.0009547968176033680.356047389148475....
BRCACAediting_468893chr6_31765025_-0.0004668140434568790.394172778410598....
LUADCAediting_468893chr6_31765025_-0.02966157707016530.174734866331612....
STADCAediting_468893chr6_31765025_-0.03868817833711010.154683660907025....
THCACAediting_468893chr6_31765025_-0.007829010732669670.14421330332457....
KIRCCAediting_468893chr6_31765025_-0.0115699235485150.215163627216342....
UCECCAediting_468893chr6_31765025_-0.0006463255911162340.358677595340657....
KIRPCAediting_468893chr6_31765025_-0.01636826981211060.1602553149188773.01827232333875e-070.334225076539771..
ESCACAediting_468893chr6_31765025_-0.005309318732809060.352670808211556....
OVCAediting_468893chr6_31765025_-0.001206833415832040.220376812323728....
PCPGCAediting_468893chr6_31765025_-0.03660734200497990.187170600157517....
ESCACAediting_468894chr6_31765030_-..0.04793297377101390.258642601422773..
BRCACAediting_468900chr6_31765070_-0.0006621573905113320.461035732888832....
LUADCAediting_468900chr6_31765070_-0.01016950335100990.257201500815413....
THCACAediting_468900chr6_31765070_-2.25803138118744e-050.319751974810485....
KIRPCAediting_468900chr6_31765070_-0.002063113655223610.313906969661697....
OVCAediting_468900chr6_31765070_-0.03435016133994850.291257403423606....
PCPGCAediting_468900chr6_31765070_-0.0002040431513931480.3649418428346450.001243602534942330.319982879515725..
BRCACAediting_468901chr6_31765071_-0.001345043504535530.365924772903424....
LIHCCAediting_468901chr6_31765071_-0.02960857932103760.283427412809869....
LUADCAediting_468901chr6_31765071_-0.0004186616142348580.267609856853243....
THCACAediting_468901chr6_31765071_-9.18226738732874e-090.303103848858168....
UCECCAediting_468901chr6_31765071_-1.26178022713028e-060.563286545474958....
KIRPCAediting_468901chr6_31765071_-0.006561587799338640.187483749923307....
OVCAediting_468901chr6_31765071_-3.59321994341535e-060.442532928670835....
PAADCAediting_468901chr6_31765071_-0.001808056382162490.388467561027447....
PCPGCAediting_468901chr6_31765071_-0.0001457383931705910.360693584176309....
BRCACAediting_468903chr6_31765087_-0.01908788173534460.304371729471625....
LUADCAediting_468903chr6_31765087_-0.03289273533335740.248330290265488....
THCACAediting_468903chr6_31765087_-0.0003520664583336950.334674803987782....
KIRCCAediting_468903chr6_31765087_-0.0005140139542787630.441965515840158....
PCPGCAediting_468903chr6_31765087_-2.60856503031704e-060.5185485517140550.03691815115971990.244722937994795..
BRCACAediting_468904chr6_31765181_-0.004200594694591790.314838747723669....
LIHCCAediting_468904chr6_31765181_-0.006881512656714610.311604004064082....
LUADCAediting_468904chr6_31765181_-0.0001712260565806850.280373648829705....
STADCAediting_468904chr6_31765181_-0.002870632484075350.27799441935315....
THCACAediting_468904chr6_31765181_-1.04202025332808e-100.341551858894768....
KIRCCAediting_468904chr6_31765181_-0.0003366464107556650.3657581557702130.007328576994343130.277840710742207..
UCECCAediting_468904chr6_31765181_-4.27643591279766e-060.594255006551907....
KIRPCAediting_468904chr6_31765181_-0.0002113670335193230.282126548321967....
OVCAediting_468904chr6_31765181_-1.39072660696762e-060.362332882448438....
PAADCAediting_468904chr6_31765181_-0.0001162124175911980.44439860275076....
PCPGCAediting_468904chr6_31765181_-4.96905128108819e-070.4349775761651940.00430817483233080.255713860958334..
STADCAediting_468905chr6_31765193_-0.03693218977500160.203919029947174....
OVCAediting_468905chr6_31765193_-6.97663364133429e-080.412927080814047....
STADCAediting_468906chr6_31765194_-0.001539322951503990.26340108239128....
OVCAediting_468906chr6_31765194_-9.68180745933006e-070.335810345627322....
STADCAediting_468908chr6_31765352_-....0.03336241274629750.175027072748395
ESCACAediting_468908chr6_31765352_-0.00474078265004760.385733090899029....
OVCAediting_468908chr6_31765352_-5.81416066442527e-050.295805886071156....
THCACAediting_468909chr6_31765356_-0.03702118834043660.272187228265576....
KIRPCAediting_468909chr6_31765356_-0.02055479560409080.250894731482006....
OVCAediting_468909chr6_31765356_-6.73626900906887e-050.281421062382753....
STADCAediting_468910chr6_31765357_-1.23902511350976e-050.351887559464403....
ESCACAediting_468910chr6_31765357_-0.009547262605600150.3528928421439180.03553437730185080.289450507138902..
OVCAediting_468910chr6_31765357_-2.54889385205186e-050.309960772536784....
LUADCAediting_468911chr6_31765376_-0.03600645495191910.297317647679418....
STADCAediting_468911chr6_31765376_-....0.0435288923857760.175331461954516
KIRPCAediting_468911chr6_31765376_-..1.13134307525307e-110.528797061230117..
OVCAediting_468911chr6_31765376_-0.01560858533501420.184665932985929....
THCACAediting_468913chr6_31765393_-0.0006962219730778870.285239912856539....
OVCAediting_468913chr6_31765393_-0.0003414741078579210.305971279321941....
BRCACAediting_468916chr6_31765430_-0.03940805570324060.152844738439849....
LUADCAediting_468916chr6_31765430_-5.67650030570362e-050.249341472599069....
LUSCCAediting_468916chr6_31765430_-0.02505161558048690.24016438984233....
THCACAediting_468916chr6_31765430_-0.002215145303736180.151073861504014....

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Relation with cancer stages for SAPCD1-AS1

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
ESCAclinical_stageCAediting_468890chr6_31764993_-0.0314350087289863-0.646958096444259
KIRCpathologic_stageCAediting_468901chr6_31765071_-0.008688246892101390.254890996713448
KIRPclinical_stageCAediting_468901chr6_31765071_-0.02823681747341780.1822487988816
KIRPclinical_stageCAediting_468916chr6_31765430_-0.03110628961359290.173241695245703
KIRPpathologic_stageCAediting_468890chr6_31764993_-0.00356353791678431-0.197945029742329
KIRPpathologic_stageCAediting_468901chr6_31765071_-0.03938562965598180.150398143980541
KIRPpathologic_stageCAediting_468916chr6_31765430_-0.02788603269448990.15249147701953
LUADpathologic_stageCAediting_468894chr6_31765030_-0.00428809793691480.263341336317333
LUSCpathologic_stageCAediting_468916chr6_31765430_-0.02808880591497270.238280271536112
OVclinical_stageCAediting_468913chr6_31765393_-0.001623653979650310.273759344099888
THCApathologic_stageCAediting_468891chr6_31765005_-0.03917593366030210.169729923265531
THCApathologic_stageCAediting_468893chr6_31765025_-0.009063483111364750.142811226462252
THCApathologic_stageCAediting_468901chr6_31765071_-0.03531151269229850.114026269679883

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Relation with survival for SAPCD1-AS1

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
CESCCAediting_468890chr6_31764993_-0.01267054453307670.01296443338090
STADCAediting_468911chr6_31765376_-0.03780647171634990.030959210.3197
KIRCCAediting_468904chr6_31765181_-0.01032036430350170.00733755421.574
KIRPCAediting_468894chr6_31765030_-0.02004346789985220.03365490.0574026
OVCAediting_468913chr6_31765393_-0.04129992032241210.03150070.080458

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RelatedDrugs for SAPCD1-AS1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SAPCD1-AS1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource