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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: IRF9 (CAeditome ID:10379) |
Gene summary for IRF9 |
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Gene information | Gene symbol | IRF9 | Gene ID | 10379 |
Gene name | interferon regulatory factor 9 | |
Synonyms | IRF-9|ISGF3|ISGF3G|p48 | |
Cytomap | 14q12 | |
Type of gene | protein-coding | |
Description | interferon regulatory factor 9IFN-alpha-responsive transcription factor subunitISGF-3 gammaISGF3 p48 subunitinterferon-stimulated gene factor 3 gammainterferon-stimulated transcription factor 3, gamma (48kD)interferon-stimulated transcription factor | |
Modification date | 20210522 | |
UniProtAcc | Q00978 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
IRF9 | GO:1990837 | Interferon regulatory factor 9 | 28473536 |
IRF9 | GO:0005829 | Interferon regulatory factor 9 | 0000052 |
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RNA A-to-I events for IRF9 |
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CAediting_979092(24163648, +), CAediting_979093(24163682, +), CAediting_979094(24163731, +), CAediting_979095(24163846, +), CAediting_979096(24165171, +), CAediting_979097(24165710, +), |
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RNA editing positional annotations for IRF9 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
CAediting_979096 | chr14_24165171_+ | nonsynonymous SNV | ENST00000557894.4 | c.A800G | p.K267R | D | . | N |
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CAeditome ID | Position | Variant type |
CAediting_979092 | chr14_24163648_+ | ncRNA_exonic |
CAediting_979093 | chr14_24163682_+ | ncRNA_exonic |
CAediting_979094 | chr14_24163731_+ | ncRNA_exonic |
CAediting_979095 | chr14_24163846_+ | ncRNA_exonic |
CAediting_979096 | chr14_24165171_+ | exonic |
CAediting_979097 | chr14_24165710_+ | ncRNA_intronic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_979092 | chr14_24163648_+ | SINE | Alu | AluSq |
CAediting_979093 | chr14_24163682_+ | SINE | Alu | AluSq |
CAediting_979094 | chr14_24163731_+ | SINE | Alu | AluSq |
CAediting_979095 | chr14_24163846_+ | SINE | Alu | AluSq |
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RNA A-to-I editing events in the alternative splicing sites for IRF9 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for IRF9 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for IRF9 |
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The effects of the RNA editing to the miRNA binding sites for IRF9 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_979093 | chr14_24163682_+ | ENSG00000213928.7 | ENST00000560852 | hsa-miR-3680-3p | 24163679 | 24163686 | 8mer-1a | 24163664 | 24163686 | 140.00 | -14.25 |
CAediting_979093 | chr14_24163682_+ | ENSG00000213928.7 | ENST00000560852 | hsa-miR-3680-3p | 24163679 | 24163686 | 8mer-1a | 24163664 | 24163686 | 140.00 | -14.25 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_979094 | chr14_24163731_+ | ENSG00000213928.7 | ENST00000560852 | hsa-miR-1200 | 24163727 | 24163733 | 7mer-m8 | 24163713 | 24163734 | 141 | -17.86 |
CAediting_979094 | chr14_24163731_+ | ENSG00000213928.7 | ENST00000560852 | hsa-miR-6869-5p | 24163724 | 24163730 | 7mer-m8 | 24163709 | 24163731 | 146 | -19.73 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_604450 | chr7_133034877_- | ENSG00000213928.7 | ENST00000561342 | hsa-miR-3654 | 24163011 | 24163017 | 7mer-m8 | 24163000 | 24163018 | 148 | -18.61 |
CAediting_1160181 | chr17_7017644_- | ENSG00000213928.7 | ENST00000561342 | hsa-miR-195-3p | 24163914 | 24163919 | 6mer | 24163898 | 24163920 | 151 | -28.3 |
CAediting_604450 | chr7_133034877_- | ENSG00000213928.7 | ENST00000560852 | hsa-miR-3654 | 24163011 | 24163017 | 7mer-m8 | 24163000 | 24163018 | 148 | -18.61 |
CAediting_1524209 | chrX_134546392_- | ENSG00000213928.7 | ENST00000561342 | hsa-miR-503-5p | 24164902 | 24164907 | 6mer | 24164886 | 24164908 | 144 | -20.29 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for IRF9 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for IRF9 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for IRF9 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for IRF9 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for IRF9 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for IRF9 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |