![]() |
||||||
|
![]() | |
![]() | |
![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
![]() | |
![]() | |
![]() | The effects of the RNA editing to the stability of the RNA structures |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Editing gene: SPRY2 (CAeditome ID:10253) |
Gene summary for SPRY2 |
![]() |
Gene information | Gene symbol | SPRY2 | Gene ID | 10253 |
Gene name | sprouty RTK signaling antagonist 2 | |
Synonyms | IGAN3|hSPRY2 | |
Cytomap | 13q31.1 | |
Type of gene | protein-coding | |
Description | protein sprouty homolog 2 | |
Modification date | 20210518 | |
UniProtAcc | O43597 | |
Context | - 32160544(Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling) |
![]() |
Gene | GO ID | GO term | PubMed ID |
SPRY2 | GO:0010801 | Protein sprouty homolog 2 | 20736167 |
SPRY2 | GO:0031397 | Protein sprouty homolog 2 | 17974561 |
SPRY2 | GO:0035924 | Protein sprouty homolog 2 | 21536891 |
SPRY2 | GO:0070373 | Protein sprouty homolog 2 | 21536891 |
SPRY2 | GO:1900747 | Protein sprouty homolog 2 | 21536891 |
SPRY2 | GO:0015629 | Protein sprouty homolog 2 | 0000052 |
SPRY2 | GO:0015630 | Protein sprouty homolog 2 | 0000052 |
SPRY2 | GO:1990752 | Protein sprouty homolog 2 | 0000052 |
Top |
RNA A-to-I events for SPRY2 |
![]() |
![]() |
![]() |
![]() |
CAediting_968471(80336973, -), CAediting_968472(80340655, -), CAediting_968473(80340714, -), CAediting_968474(80340734, -), CAediting_968475(80340835, -), |
Top |
RNA editing positional annotations for SPRY2 using Annovar |
![]() |
CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
![]() |
CAeditome ID | Position | Variant type |
CAediting_968471 | chr13_80336973_- | exonic |
CAediting_968472 | chr13_80340655_- | UTR5 |
CAediting_968473 | chr13_80340714_- | UTR5 |
CAediting_968474 | chr13_80340734_- | UTR5 |
CAediting_968475 | chr13_80340835_- | UTR5 |
![]() |
CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
Top |
RNA A-to-I editing events in the alternative splicing sites for SPRY2 |
![]() |
AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
![]() |
![]() |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for SPRY2 |
![]() * The grey color means N/A. |
![]() |
![]() * Click on the image to enlarge it in a new window. |
Top |
Protein coding region RNA A-to-I editings for SPRY2 |
![]() * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for SPRY2 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
Top |
The effects of the RNA editing to the stability of the RNA structures for SPRY2 |
![]() * Click on the image to enlarge it in a new window. |
ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
![]() |
CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for SPRY2 |
![]() |
Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
Top |
Relation with cancer stages for SPRY2 |
![]() |
Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
Top |
Relation with survival for SPRY2 |
![]() |
Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
Top |
RelatedDrugs for SPRY2 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for SPRY2 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
SPRY2 | C0008924 | Cleft upper lip | 1 | CTD_human |
SPRY2 | C0008925 | Cleft Palate | 1 | CTD_human |
SPRY2 | C0024115 | Lung diseases | 1 | CTD_human |
SPRY2 | C0024121 | Lung Neoplasms | 1 | CTD_human |
SPRY2 | C0242379 | Malignant neoplasm of lung | 1 | CTD_human |
SPRY2 | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
SPRY2 | C1837218 | Cleft palate, isolated | 1 | CTD_human |
SPRY2 | C4225194 | IgA NEPHROPATHY, SUSCEPTIBILITY TO, 3 | 1 | UNIPROT |