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Editing gene: GLYAT (CAeditome ID:10249)

Gene summary for GLYAT

Gene summary

Gene information	Gene symbol	GLYAT
	Gene ID	10249
	Gene name	glycine-N-acyltransferase
	Synonyms	ACGNAT\|CAT\|GAT
	Cytomap	11q12.1
	Type of gene	protein-coding
	Description	glycine N-acyltransferaseAAcHRP-1(CLP)acyl-CoA:glycine N-acyltransferasearalkyl acyl-CoA N-acyltransferasearalkyl acyl-CoA:amino acid N-acyltransferasearalkyl-CoA N-acyltransferasebenzoyl-coenzyme A:glycine N-acyltransferaseepididymis secretory sp
	Modification date	20210518
	UniProtAcc	Q6IB77
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
GLYAT	GO:0047961	Glycine N-acyltransferase	22475485
GLYAT	GO:0047962	Glycine N-acyltransferase	22475485
GLYAT	GO:0006544	Glycine N-acyltransferase	22475485
GLYAT	GO:1901787	Glycine N-acyltransferase	22475485
GLYAT	GO:0005739	Glycine N-acyltransferase	22475485

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RNA A-to-I events for GLYAT

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000149124.9

RNA A-to-I editing events in Cancer.

CAediting_815202(58693643, -), CAediting_815203(58693739, -), CAediting_815204(58693742, -), CAediting_815205(58693748, -), CAediting_815206(58693755, -), CAediting_815207(58693756, -), CAediting_815208(58693760, -), CAediting_815209(58693782, -), CAediting_815210(58693788, -), CAediting_815211(58693804, -), CAediting_815212(58693817, -), CAediting_815213(58693842, -), CAediting_815214(58693852, -), CAediting_815215(58693857, -), CAediting_815216(58693898, -), CAediting_815217(58694785, -), CAediting_815218(58701356, -), CAediting_815219(58701359, -), CAediting_815220(58701381, -), CAediting_815221(58701393, -), CAediting_815222(58701447, -), CAediting_815223(58701449, -), CAediting_815224(58701452, -), CAediting_815225(58701469, -), CAediting_815226(58701493, -), CAediting_815227(58701495, -), CAediting_815228(58701505, -), CAediting_815229(58701508, -), CAediting_815230(58701509, -), CAediting_815231(58701517, -), CAediting_815232(58701534, -), CAediting_815233(58701535, -), CAediting_815234(58701541, -), CAediting_815235(58701565, -), CAediting_815236(58701570, -), CAediting_815237(58702213, -), CAediting_815238(58702214, -), CAediting_815239(58702215, -), CAediting_815240(58702222, -), CAediting_815241(58702225, -), CAediting_815242(58702230, -), CAediting_815243(58702231, -), CAediting_815244(58702243, -), CAediting_815245(58702251, -), CAediting_815246(58702278, -), CAediting_815247(58702286, -), CAediting_815248(58702288, -), CAediting_815249(58702293, -), CAediting_815250(58702297, -), CAediting_815251(58702304, -), CAediting_815252(58702317, -), CAediting_815253(58702326, -), CAediting_815254(58702332, -), CAediting_815255(58702336, -), CAediting_815256(58702342, -), CAediting_815257(58702349, -), CAediting_815258(58702353, -), CAediting_815259(58702359, -), CAediting_815260(58702385, -), CAediting_815261(58702388, -), CAediting_815262(58702389, -), CAediting_815263(58702390, -), CAediting_815264(58702391, -), CAediting_815265(58702392, -), CAediting_815266(58702393, -), CAediting_815267(58702397, -), CAediting_815268(58702398, -), CAediting_815269(58702399, -), CAediting_815270(58702403, -), CAediting_815271(58702409, -), CAediting_815272(58702414, -), CAediting_815273(58702415, -), CAediting_815274(58702416, -), CAediting_815275(58702422, -), CAediting_815276(58702448, -), CAediting_815277(58702452, -), CAediting_815278(58702470, -), CAediting_815279(58702473, -), CAediting_815280(58702478, -), CAediting_815281(58702479, -), CAediting_815282(58702485, -), CAediting_815283(58702487, -), CAediting_815284(58702494, -), CAediting_815285(58702502, -), CAediting_815286(58702727, -), CAediting_815287(58702729, -), CAediting_815288(58702733, -), CAediting_815289(58702742, -), CAediting_815290(58702745, -), CAediting_815291(58702746, -), CAediting_815292(58702755, -), CAediting_815293(58702760, -), CAediting_815294(58704020, -), CAediting_815295(58705761, -), CAediting_815296(58708127, -), CAediting_815297(58708129, -), CAediting_815298(58708138, -), CAediting_815299(58708167, -), CAediting_815300(58708171, -), CAediting_815301(58708173, -), CAediting_815302(58708183, -), CAediting_815303(58708188, -), CAediting_815304(58708195, -), CAediting_815305(58708212, -), CAediting_815306(58708219, -), CAediting_815307(58708226, -), CAediting_815308(58708233, -), CAediting_815309(58708257, -), CAediting_815310(58708289, -), CAediting_815311(58708313, -), CAediting_815312(58725793, -), CAediting_815313(58725801, -), CAediting_815314(58726013, -), CAediting_815315(58726035, -), CAediting_815316(58727855, -), CAediting_815317(58728005, -),

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RNA editing positional annotations for GLYAT using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_815202	chr11_58693643_-	intronic
CAediting_815203	chr11_58693739_-	intronic
CAediting_815204	chr11_58693742_-	intronic
CAediting_815205	chr11_58693748_-	intronic
CAediting_815206	chr11_58693755_-	intronic
CAediting_815207	chr11_58693756_-	intronic
CAediting_815208	chr11_58693760_-	intronic
CAediting_815209	chr11_58693782_-	intronic
CAediting_815210	chr11_58693788_-	intronic
CAediting_815211	chr11_58693804_-	intronic
CAediting_815212	chr11_58693817_-	intronic
CAediting_815213	chr11_58693842_-	intronic
CAediting_815214	chr11_58693852_-	intronic
CAediting_815215	chr11_58693857_-	intronic
CAediting_815216	chr11_58693898_-	intronic
CAediting_815217	chr11_58694785_-	intronic
CAediting_815218	chr11_58701356_-	intronic
CAediting_815219	chr11_58701359_-	intronic
CAediting_815220	chr11_58701381_-	intronic
CAediting_815221	chr11_58701393_-	intronic
CAediting_815222	chr11_58701447_-	intronic
CAediting_815223	chr11_58701449_-	intronic
CAediting_815224	chr11_58701452_-	intronic
CAediting_815225	chr11_58701469_-	intronic
CAediting_815226	chr11_58701493_-	intronic
CAediting_815227	chr11_58701495_-	intronic
CAediting_815228	chr11_58701505_-	intronic
CAediting_815229	chr11_58701508_-	intronic
CAediting_815230	chr11_58701509_-	intronic
CAediting_815231	chr11_58701517_-	intronic
CAediting_815232	chr11_58701534_-	intronic
CAediting_815233	chr11_58701535_-	intronic
CAediting_815234	chr11_58701541_-	intronic
CAediting_815235	chr11_58701565_-	intronic
CAediting_815236	chr11_58701570_-	intronic
CAediting_815237	chr11_58702213_-	intronic
CAediting_815238	chr11_58702214_-	intronic
CAediting_815239	chr11_58702215_-	intronic
CAediting_815240	chr11_58702222_-	intronic
CAediting_815241	chr11_58702225_-	intronic
CAediting_815242	chr11_58702230_-	intronic
CAediting_815243	chr11_58702231_-	intronic
CAediting_815244	chr11_58702243_-	intronic
CAediting_815245	chr11_58702251_-	intronic
CAediting_815246	chr11_58702278_-	intronic
CAediting_815247	chr11_58702286_-	intronic
CAediting_815248	chr11_58702288_-	intronic
CAediting_815249	chr11_58702293_-	intronic
CAediting_815250	chr11_58702297_-	intronic
CAediting_815251	chr11_58702304_-	intronic
CAediting_815252	chr11_58702317_-	intronic
CAediting_815253	chr11_58702326_-	intronic
CAediting_815254	chr11_58702332_-	intronic
CAediting_815255	chr11_58702336_-	intronic
CAediting_815256	chr11_58702342_-	intronic
CAediting_815257	chr11_58702349_-	intronic
CAediting_815258	chr11_58702353_-	intronic
CAediting_815259	chr11_58702359_-	intronic
CAediting_815260	chr11_58702385_-	intronic
CAediting_815261	chr11_58702388_-	intronic
CAediting_815262	chr11_58702389_-	intronic
CAediting_815263	chr11_58702390_-	intronic
CAediting_815264	chr11_58702391_-	intronic
CAediting_815265	chr11_58702392_-	intronic
CAediting_815266	chr11_58702393_-	intronic
CAediting_815267	chr11_58702397_-	intronic
CAediting_815268	chr11_58702398_-	intronic
CAediting_815269	chr11_58702399_-	intronic
CAediting_815270	chr11_58702403_-	intronic
CAediting_815271	chr11_58702409_-	intronic
CAediting_815272	chr11_58702414_-	intronic
CAediting_815273	chr11_58702415_-	intronic
CAediting_815274	chr11_58702416_-	intronic
CAediting_815275	chr11_58702422_-	intronic
CAediting_815276	chr11_58702448_-	intronic
CAediting_815277	chr11_58702452_-	intronic
CAediting_815278	chr11_58702470_-	intronic
CAediting_815279	chr11_58702473_-	intronic
CAediting_815280	chr11_58702478_-	intronic
CAediting_815281	chr11_58702479_-	intronic
CAediting_815282	chr11_58702485_-	intronic
CAediting_815283	chr11_58702487_-	intronic
CAediting_815284	chr11_58702494_-	intronic
CAediting_815285	chr11_58702502_-	intronic
CAediting_815286	chr11_58702727_-	intronic
CAediting_815287	chr11_58702729_-	intronic
CAediting_815288	chr11_58702733_-	intronic
CAediting_815289	chr11_58702742_-	intronic
CAediting_815290	chr11_58702745_-	intronic
CAediting_815291	chr11_58702746_-	intronic
CAediting_815292	chr11_58702755_-	intronic
CAediting_815293	chr11_58702760_-	intronic
CAediting_815294	chr11_58704020_-	intronic
CAediting_815295	chr11_58705761_-	intronic
CAediting_815296	chr11_58708127_-	intronic
CAediting_815297	chr11_58708129_-	intronic
CAediting_815298	chr11_58708138_-	intronic
CAediting_815299	chr11_58708167_-	intronic
CAediting_815300	chr11_58708171_-	intronic
CAediting_815301	chr11_58708173_-	intronic
CAediting_815302	chr11_58708183_-	intronic
CAediting_815303	chr11_58708188_-	intronic
CAediting_815304	chr11_58708195_-	intronic
CAediting_815305	chr11_58708212_-	intronic
CAediting_815306	chr11_58708219_-	intronic
CAediting_815307	chr11_58708226_-	intronic
CAediting_815308	chr11_58708233_-	intronic
CAediting_815309	chr11_58708257_-	intronic
CAediting_815310	chr11_58708289_-	intronic
CAediting_815311	chr11_58708313_-	intronic
CAediting_815312	chr11_58725793_-	ncRNA_intronic
CAediting_815313	chr11_58725801_-	ncRNA_intronic
CAediting_815314	chr11_58726013_-	ncRNA_intronic
CAediting_815315	chr11_58726035_-	ncRNA_intronic
CAediting_815316	chr11_58727855_-	ncRNA_intronic
CAediting_815317	chr11_58728005_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_815202	chr11_58693643_-	SINE	Alu	AluSz
CAediting_815203	chr11_58693739_-	SINE	Alu	AluSz
CAediting_815204	chr11_58693742_-	SINE	Alu	AluSz
CAediting_815205	chr11_58693748_-	SINE	Alu	AluSz
CAediting_815206	chr11_58693755_-	SINE	Alu	AluSz
CAediting_815207	chr11_58693756_-	SINE	Alu	AluSz
CAediting_815208	chr11_58693760_-	SINE	Alu	AluSz
CAediting_815209	chr11_58693782_-	SINE	Alu	AluSz
CAediting_815210	chr11_58693788_-	SINE	Alu	AluSz
CAediting_815211	chr11_58693804_-	SINE	Alu	AluSz
CAediting_815212	chr11_58693817_-	SINE	Alu	AluSz
CAediting_815213	chr11_58693842_-	SINE	Alu	AluSz
CAediting_815214	chr11_58693852_-	SINE	Alu	AluSz
CAediting_815215	chr11_58693857_-	SINE	Alu	AluSz
CAediting_815216	chr11_58693898_-	SINE	Alu	AluSz
CAediting_815217	chr11_58694785_-	Simple_repeat	Simple_repeat	(GATATA)n
CAediting_815218	chr11_58701356_-	SINE	Alu	AluSq2
CAediting_815219	chr11_58701359_-	SINE	Alu	AluSq2
CAediting_815220	chr11_58701381_-	SINE	Alu	AluSq2
CAediting_815221	chr11_58701393_-	SINE	Alu	AluSq2
CAediting_815222	chr11_58701447_-	SINE	Alu	AluSq2
CAediting_815223	chr11_58701449_-	SINE	Alu	AluSq2
CAediting_815224	chr11_58701452_-	SINE	Alu	AluSq2
CAediting_815225	chr11_58701469_-	SINE	Alu	AluSq2
CAediting_815226	chr11_58701493_-	SINE	Alu	AluSq2
CAediting_815227	chr11_58701495_-	SINE	Alu	AluSq2
CAediting_815228	chr11_58701505_-	SINE	Alu	AluSq2
CAediting_815229	chr11_58701508_-	SINE	Alu	AluSq2
CAediting_815230	chr11_58701509_-	SINE	Alu	AluSq2
CAediting_815231	chr11_58701517_-	SINE	Alu	AluSq2
CAediting_815232	chr11_58701534_-	SINE	Alu	AluSq2
CAediting_815233	chr11_58701535_-	SINE	Alu	AluSq2
CAediting_815234	chr11_58701541_-	SINE	Alu	AluSq2
CAediting_815235	chr11_58701565_-	SINE	Alu	AluSq2
CAediting_815236	chr11_58701570_-	SINE	Alu	AluSq2
CAediting_815237	chr11_58702213_-	SINE	Alu	AluSc
CAediting_815238	chr11_58702214_-	SINE	Alu	AluSc
CAediting_815239	chr11_58702215_-	SINE	Alu	AluSc
CAediting_815240	chr11_58702222_-	SINE	Alu	AluSc
CAediting_815241	chr11_58702225_-	SINE	Alu	AluSc
CAediting_815242	chr11_58702230_-	SINE	Alu	AluSc
CAediting_815243	chr11_58702231_-	SINE	Alu	AluSc
CAediting_815244	chr11_58702243_-	SINE	Alu	AluSc
CAediting_815245	chr11_58702251_-	SINE	Alu	AluSc
CAediting_815246	chr11_58702278_-	SINE	Alu	AluSc
CAediting_815247	chr11_58702286_-	SINE	Alu	AluSc
CAediting_815248	chr11_58702288_-	SINE	Alu	AluSc
CAediting_815249	chr11_58702293_-	SINE	Alu	AluSc
CAediting_815250	chr11_58702297_-	SINE	Alu	AluSc
CAediting_815251	chr11_58702304_-	SINE	Alu	AluSc
CAediting_815252	chr11_58702317_-	SINE	Alu	AluSc
CAediting_815253	chr11_58702326_-	SINE	Alu	AluSc
CAediting_815254	chr11_58702332_-	SINE	Alu	AluSc
CAediting_815255	chr11_58702336_-	SINE	Alu	AluSc
CAediting_815256	chr11_58702342_-	SINE	Alu	AluSc
CAediting_815257	chr11_58702349_-	SINE	Alu	AluSc
CAediting_815258	chr11_58702353_-	SINE	Alu	AluSc
CAediting_815259	chr11_58702359_-	SINE	Alu	AluSc
CAediting_815260	chr11_58702385_-	SINE	Alu	AluSc
CAediting_815261	chr11_58702388_-	SINE	Alu	AluSc
CAediting_815262	chr11_58702389_-	SINE	Alu	AluSc
CAediting_815263	chr11_58702390_-	SINE	Alu	AluSc
CAediting_815264	chr11_58702391_-	SINE	Alu	AluSc
CAediting_815265	chr11_58702392_-	SINE	Alu	AluSc
CAediting_815266	chr11_58702393_-	SINE	Alu	AluSc
CAediting_815267	chr11_58702397_-	SINE	Alu	AluSc
CAediting_815268	chr11_58702398_-	SINE	Alu	AluSc
CAediting_815269	chr11_58702399_-	SINE	Alu	AluSc
CAediting_815270	chr11_58702403_-	SINE	Alu	AluSc
CAediting_815271	chr11_58702409_-	SINE	Alu	AluSc
CAediting_815272	chr11_58702414_-	SINE	Alu	AluSc
CAediting_815273	chr11_58702415_-	SINE	Alu	AluSc
CAediting_815274	chr11_58702416_-	SINE	Alu	AluSc
CAediting_815275	chr11_58702422_-	SINE	Alu	AluSc
CAediting_815276	chr11_58702448_-	SINE	Alu	AluSc
CAediting_815277	chr11_58702452_-	SINE	Alu	AluSc
CAediting_815278	chr11_58702470_-	SINE	Alu	AluSc
CAediting_815279	chr11_58702473_-	SINE	Alu	AluSc
CAediting_815280	chr11_58702478_-	SINE	Alu	AluSc
CAediting_815281	chr11_58702479_-	SINE	Alu	AluSc
CAediting_815282	chr11_58702485_-	SINE	Alu	AluSc
CAediting_815283	chr11_58702487_-	SINE	Alu	AluSc
CAediting_815284	chr11_58702494_-	SINE	Alu	AluSc
CAediting_815285	chr11_58702502_-	SINE	Alu	AluSc
CAediting_815286	chr11_58702727_-	SINE	Alu	AluJr
CAediting_815287	chr11_58702729_-	SINE	Alu	AluJr
CAediting_815288	chr11_58702733_-	SINE	Alu	AluJr
CAediting_815289	chr11_58702742_-	SINE	Alu	AluJr
CAediting_815290	chr11_58702745_-	SINE	Alu	AluJr
CAediting_815291	chr11_58702746_-	SINE	Alu	AluJr
CAediting_815292	chr11_58702755_-	SINE	Alu	AluJr
CAediting_815293	chr11_58702760_-	SINE	Alu	AluJr
CAediting_815294	chr11_58704020_-	LINE	L1	L1PA17
CAediting_815295	chr11_58705761_-	LINE	L1	L1PA17
CAediting_815296	chr11_58708127_-	SINE	Alu	AluSx
CAediting_815297	chr11_58708129_-	SINE	Alu	AluSx
CAediting_815298	chr11_58708138_-	SINE	Alu	AluSx
CAediting_815299	chr11_58708167_-	SINE	Alu	AluSx
CAediting_815300	chr11_58708171_-	SINE	Alu	AluSx
CAediting_815301	chr11_58708173_-	SINE	Alu	AluSx
CAediting_815302	chr11_58708183_-	SINE	Alu	AluSx
CAediting_815303	chr11_58708188_-	SINE	Alu	AluSx
CAediting_815304	chr11_58708195_-	SINE	Alu	AluSx
CAediting_815305	chr11_58708212_-	SINE	Alu	AluSx
CAediting_815306	chr11_58708219_-	SINE	Alu	AluSx
CAediting_815307	chr11_58708226_-	SINE	Alu	AluSx
CAediting_815308	chr11_58708233_-	SINE	Alu	AluSx
CAediting_815309	chr11_58708257_-	SINE	Alu	AluSx
CAediting_815310	chr11_58708289_-	SINE	Alu	AluSx
CAediting_815311	chr11_58708313_-	SINE	Alu	AluSx
CAediting_815312	chr11_58725793_-	LTR	ERV1	MER50
CAediting_815313	chr11_58725801_-	LTR	ERV1	MER50
CAediting_815314	chr11_58726013_-	LTR	ERV1	MER50
CAediting_815315	chr11_58726035_-	LTR	ERV1	MER50
CAediting_815316	chr11_58727855_-	LTR	ERV1	MER50
CAediting_815317	chr11_58728005_-	LTR	ERV1	MER50

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RNA A-to-I editing events in the alternative splicing sites for GLYAT

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000149124.9.GLYAT.

Correlation between RNA A-to-I editing and PSI for ENSG00000149124.9.GLYAT.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for GLYAT

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

LIHC.CAediting_815280.ENSG00000149124.GLYAT.png
Soverview

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Protein coding region RNA A-to-I editings for GLYAT

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for GLYAT

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000149124.9	ENST00000586098	hsa-miR-605-3p	58640474	58640480	7mer-m8	58640473	58640492	148	-15.34
CAediting_1368054	chr19_46709310_-	ENSG00000149124.9	ENST00000586098	hsa-miR-320e	58640530	58640537	8mer-1a	58640530	58640550	146	-22.15
CAediting_442554	chr5_154685830_+	ENSG00000149124.9	ENST00000611865	hsa-miR-1303	58709168	58709174	7mer-m8	58709167	58709191	145	-15.89
CAediting_1229415	chr17_67471547_+	ENSG00000149124.9	ENST00000278400	hsa-miR-548aa	58710507	58710513	7mer-m8	58710506	58710530	148	-9.81
CAediting_228905	chr2_188297554_+	ENSG00000149124.9	ENST00000278400	hsa-miR-561-3p	58710146	58710152	7mer-m8	58710145	58710168	168	-17.33

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for GLYAT

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for GLYAT

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
KIRC	CAediting_815247	chr11_58702286_-	0.0139967636316406	0.160117800784246	.	.	.	.
LIHC	CAediting_815248	chr11_58702288_-	3.53390663105036e-05	0.518970866015855	.	.	.	.
KIRC	CAediting_815248	chr11_58702288_-	2.91304492366329e-05	0.259072452051424	.	.	.	.
KIRC	CAediting_815249	chr11_58702293_-	0.0466084501003709	0.128581327007432	.	.	.	.
KIRC	CAediting_815257	chr11_58702349_-	0.0498266062899009	0.104482114134624	.	.	.	.
KIRC	CAediting_815259	chr11_58702359_-	0.00882745293083228	0.146860739421487	.	.	.	.
KIRP	CAediting_815259	chr11_58702359_-	0.0146571464608756	0.170263312281877	0.00728678821587143	0.18690830778716	.	.
KIRC	CAediting_815274	chr11_58702416_-	0.0140048206045189	0.143662768189865	.	.	.	.
KIRP	CAediting_815274	chr11_58702416_-	7.26240799045296e-06	0.310488664597038	.	.	.	.
KIRC	CAediting_815289	chr11_58702742_-	0.00203837067263209	0.189025614379346	.	.	.	.
KIRC	CAediting_815290	chr11_58702745_-	0.0115860040648747	0.182330108019392	.	.	.	.
KIRC	CAediting_815292	chr11_58702755_-	0.00197569741401626	0.182843206246415	.	.	.	.
KIRC	CAediting_815293	chr11_58702760_-	0.0100983650052793	0.188706444192114	.	.	.	.
KIRC	CAediting_815297	chr11_58708129_-	0.000108728604498572	0.232934950223929	.	.	.	.
KIRP	CAediting_815297	chr11_58708129_-	0.000328232350164991	0.327789353477678	.	.	.	.
KIRC	CAediting_815302	chr11_58708183_-	0.000496317202025945	0.201207149318752	0.000163084868079472	0.217433765161265	.	.
KIRP	CAediting_815302	chr11_58708183_-	4.16488824061756e-05	0.328048085551219	3.42894342219662e-07	0.401937603702839	.	.
KIRC	CAediting_815311	chr11_58708313_-	2.79327670268574e-06	0.263739821731231	.	.	.	.
KIRP	CAediting_815311	chr11_58708313_-	7.69027291606117e-06	0.370544961330726	.	.	0.00548225238346338	0.235227319562799

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Relation with cancer stages for GLYAT

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
KIRC	pathologic_stage	CAediting_815223	chr11_58701449_-	0.0182368779769287	0.15042609953693
KIRC	pathologic_stage	CAediting_815289	chr11_58702742_-	0.0293708219774315	0.1343607347634
KIRP	clinical_stage	CAediting_815223	chr11_58701449_-	0.000545119847563901	0.338059176234696
KIRP	clinical_stage	CAediting_815249	chr11_58702293_-	0.000147415294124681	0.360442483525298
KIRP	clinical_stage	CAediting_815257	chr11_58702349_-	0.0136912480168353	0.202259413747346
KIRP	clinical_stage	CAediting_815290	chr11_58702745_-	0.0156696856240619	0.375102540610101
KIRP	clinical_stage	CAediting_815302	chr11_58708183_-	0.0159684506064307	0.234671713257805
KIRP	pathologic_stage	CAediting_815223	chr11_58701449_-	1.83643151620232e-05	0.359630931947058
KIRP	pathologic_stage	CAediting_815224	chr11_58701452_-	0.0349501452521313	0.225137522157911
KIRP	pathologic_stage	CAediting_815249	chr11_58702293_-	0.00024129422081805	0.300413848559987
KIRP	pathologic_stage	CAediting_815257	chr11_58702349_-	0.0461582093188635	0.141171081182667
KIRP	pathologic_stage	CAediting_815302	chr11_58708183_-	0.0307256347265875	0.186058763036013

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Relation with survival for GLYAT

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
LIHC	CAediting_815302	chr11_58708183_-	0.0333776633245859	0.0392629	187.441

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RelatedDrugs for GLYAT

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
GLYAT	Q6IB77	DB00145	Glycine	Glycine N-acyltransferase	SmallMoleculeDrug	approved\|nutraceutical\|vet_approved

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RelatedDiseases for GLYAT

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
GLYAT	C0005586	Bipolar Disorder	1	PSYGENET

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene