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Editing gene: CDK6 (CAeditome ID:1021)

Gene summary for CDK6

Gene summary

Gene information	Gene symbol	CDK6
	Gene ID	1021
	Gene name	cyclin dependent kinase 6
	Synonyms	MCPH12\|PLSTIRE
	Cytomap	7q21.2
	Type of gene	protein-coding
	Description	cyclin-dependent kinase 6cell division protein kinase 6serine/threonine-protein kinase PLSTIRE
	Modification date	20210524
	UniProtAcc	Q00534
	Context	- 34058013(Genetic variants of CHEK1, PRIM2 and CDK6 in the mitotic phase-related pathway are associated with nonsmall cell lung cancer survival)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
CDK6	GO:0004693	Cyclin-dependent kinase 6	8114739
CDK6	GO:0005524	Cyclin-dependent kinase 6	9751050
CDK6	GO:0001954	Cyclin-dependent kinase 6	10205165
CDK6	GO:0003323	Cyclin-dependent kinase 6	20668294
CDK6	GO:0006468	Cyclin-dependent kinase 6	8114739
CDK6	GO:0010468	Cyclin-dependent kinase 6	15254224
CDK6	GO:0045638	Cyclin-dependent kinase 6	17431401
CDK6	GO:0045656	Cyclin-dependent kinase 6	26542173
CDK6	GO:0045668	Cyclin-dependent kinase 6	15254224
CDK6	GO:0045786	Cyclin-dependent kinase 6	14985467
CDK6	GO:2000773	Cyclin-dependent kinase 6	17420273
CDK6	GO:0001726	Cyclin-dependent kinase 6	10205165
CDK6	GO:0005634	Cyclin-dependent kinase 6	14985467
CDK6	GO:0005654	Cyclin-dependent kinase 6	0000052
CDK6	GO:0005737	Cyclin-dependent kinase 6	14985467
CDK6	GO:0005813	Cyclin-dependent kinase 6	23918663
CDK6	GO:0005829	Cyclin-dependent kinase 6	0000052
CDK6	GO:0000307	Cyclin-dependent kinase 6	17420273

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RNA A-to-I events for CDK6

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000105810.8

RNA A-to-I editing events in Cancer.

CAediting_573865(92613435, -), CAediting_573866(92630102, -), CAediting_573867(92651018, -), CAediting_573868(92657994, -), CAediting_573869(92663442, -), CAediting_573870(92663448, -), CAediting_573871(92663457, -), CAediting_573872(92663538, -), CAediting_573873(92663543, -), CAediting_573874(92663573, -), CAediting_573875(92663579, -), CAediting_573876(92663615, -), CAediting_573877(92663618, -), CAediting_573878(92664221, -), CAediting_573879(92664878, -), CAediting_573880(92664882, -), CAediting_573881(92664897, -), CAediting_573882(92664914, -), CAediting_573883(92664924, -), CAediting_573884(92664934, -), CAediting_573885(92664950, -), CAediting_573886(92664953, -), CAediting_573887(92664954, -), CAediting_573888(92664955, -), CAediting_573889(92664956, -), CAediting_573890(92664957, -), CAediting_573891(92664958, -), CAediting_573892(92664962, -), CAediting_573893(92664964, -), CAediting_573894(92664980, -), CAediting_573895(92665006, -), CAediting_573896(92665049, -), CAediting_573897(92665052, -), CAediting_573898(92665057, -), CAediting_573899(92665058, -), CAediting_573900(92665064, -), CAediting_573901(92665093, -), CAediting_573902(92667336, -), CAediting_573903(92667416, -), CAediting_573904(92667422, -), CAediting_573905(92667425, -), CAediting_573906(92667720, -), CAediting_573907(92673942, -), CAediting_573908(92673948, -), CAediting_573909(92673987, -), CAediting_573910(92674892, -), CAediting_573911(92674900, -), CAediting_573912(92674970, -), CAediting_573913(92674996, -), CAediting_573914(92675004, -), CAediting_573915(92675037, -), CAediting_573916(92677425, -), CAediting_573917(92677497, -), CAediting_573918(92677543, -), CAediting_573919(92679817, -), CAediting_573920(92679841, -), CAediting_573921(92679946, -), CAediting_573922(92679978, -), CAediting_573923(92692657, -), CAediting_573924(92702348, -), CAediting_573925(92702397, -), CAediting_573926(92702415, -), CAediting_573927(92702519, -), CAediting_573928(92711613, -), CAediting_573929(92711660, -), CAediting_573930(92711675, -), CAediting_573931(92711732, -), CAediting_573932(92711735, -), CAediting_573933(92711736, -), CAediting_573934(92711737, -), CAediting_573935(92711740, -), CAediting_573936(92711744, -), CAediting_573937(92711745, -), CAediting_573938(92711747, -), CAediting_573939(92711750, -), CAediting_573940(92711761, -), CAediting_573941(92711762, -), CAediting_573942(92711763, -), CAediting_573943(92711764, -), CAediting_573944(92711766, -), CAediting_573945(92711771, -), CAediting_573946(92711772, -), CAediting_573947(92711792, -), CAediting_573948(92711994, -), CAediting_573949(92711995, -), CAediting_573950(92711999, -), CAediting_573951(92712007, -), CAediting_573952(92712014, -), CAediting_573953(92712024, -), CAediting_573954(92712030, -), CAediting_573955(92712039, -), CAediting_573956(92712040, -), CAediting_573957(92712073, -), CAediting_573958(92712076, -), CAediting_573959(92712097, -), CAediting_573960(92712098, -), CAediting_573961(92712103, -), CAediting_573962(92712122, -), CAediting_573963(92713019, -), CAediting_573964(92713108, -), CAediting_573965(92713131, -), CAediting_573966(92723076, -), CAediting_573967(92726522, -), CAediting_573968(92726570, -), CAediting_573969(92726610, -), CAediting_573970(92729838, -), CAediting_573971(92729845, -), CAediting_573972(92729850, -), CAediting_573973(92729878, -), CAediting_573974(92729884, -), CAediting_573975(92729888, -), CAediting_573976(92729891, -), CAediting_573977(92729896, -), CAediting_573978(92729904, -), CAediting_573979(92729959, -), CAediting_573980(92730023, -), CAediting_573981(92732201, -), CAediting_573982(92732226, -), CAediting_573983(92732272, -), CAediting_573984(92733971, -), CAediting_573985(92738448, -), CAediting_573986(92738530, -), CAediting_573987(92739909, -), CAediting_573988(92739958, -), CAediting_573989(92740009, -), CAediting_573990(92740037, -), CAediting_573991(92740053, -), CAediting_573992(92753156, -), CAediting_573993(92753189, -), CAediting_573994(92762732, -), CAediting_573995(92762792, -), CAediting_573996(92767031, -), CAediting_573997(92767049, -), CAediting_573998(92767050, -), CAediting_573999(92767079, -), CAediting_574000(92767082, -), CAediting_574001(92767083, -), CAediting_574002(92767088, -), CAediting_574003(92767089, -), CAediting_574004(92767090, -), CAediting_574005(92767091, -), CAediting_574006(92767094, -), CAediting_574007(92767100, -), CAediting_574008(92767105, -), CAediting_574009(92767106, -), CAediting_574010(92767123, -), CAediting_574011(92767124, -), CAediting_574012(92767140, -), CAediting_574013(92768065, -), CAediting_574014(92768081, -), CAediting_574015(92768093, -), CAediting_574016(92768105, -), CAediting_574017(92770974, -), CAediting_574018(92771074, -), CAediting_574019(92801838, -), CAediting_574020(92811896, -), CAediting_574021(92811908, -), CAediting_574022(92811931, -), CAediting_574023(92811969, -), CAediting_574024(92811971, -), CAediting_574025(92811988, -), CAediting_574026(92812137, -), CAediting_574027(92812510, -), CAediting_574028(92812649, -), CAediting_574029(92812653, -), CAediting_574030(92812658, -), CAediting_574031(92812698, -), CAediting_574032(92812699, -), CAediting_574033(92812707, -),

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RNA editing positional annotations for CDK6 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_573865	chr7_92613435_-	UTR3
CAediting_573866	chr7_92630102_-	intronic
CAediting_573867	chr7_92651018_-	intronic
CAediting_573868	chr7_92657994_-	intronic
CAediting_573869	chr7_92663442_-	intronic
CAediting_573870	chr7_92663448_-	intronic
CAediting_573871	chr7_92663457_-	intronic
CAediting_573872	chr7_92663538_-	intronic
CAediting_573873	chr7_92663543_-	intronic
CAediting_573874	chr7_92663573_-	intronic
CAediting_573875	chr7_92663579_-	intronic
CAediting_573876	chr7_92663615_-	intronic
CAediting_573877	chr7_92663618_-	intronic
CAediting_573878	chr7_92664221_-	intronic
CAediting_573879	chr7_92664878_-	intronic
CAediting_573880	chr7_92664882_-	intronic
CAediting_573881	chr7_92664897_-	intronic
CAediting_573882	chr7_92664914_-	intronic
CAediting_573883	chr7_92664924_-	intronic
CAediting_573884	chr7_92664934_-	intronic
CAediting_573885	chr7_92664950_-	intronic
CAediting_573886	chr7_92664953_-	intronic
CAediting_573887	chr7_92664954_-	intronic
CAediting_573888	chr7_92664955_-	intronic
CAediting_573889	chr7_92664956_-	intronic
CAediting_573890	chr7_92664957_-	intronic
CAediting_573891	chr7_92664958_-	intronic
CAediting_573892	chr7_92664962_-	intronic
CAediting_573893	chr7_92664964_-	intronic
CAediting_573894	chr7_92664980_-	intronic
CAediting_573895	chr7_92665006_-	intronic
CAediting_573896	chr7_92665049_-	intronic
CAediting_573897	chr7_92665052_-	intronic
CAediting_573898	chr7_92665057_-	intronic
CAediting_573899	chr7_92665058_-	intronic
CAediting_573900	chr7_92665064_-	intronic
CAediting_573901	chr7_92665093_-	intronic
CAediting_573902	chr7_92667336_-	intronic
CAediting_573903	chr7_92667416_-	intronic
CAediting_573904	chr7_92667422_-	intronic
CAediting_573905	chr7_92667425_-	intronic
CAediting_573906	chr7_92667720_-	intronic
CAediting_573907	chr7_92673942_-	ncRNA_intronic
CAediting_573908	chr7_92673948_-	ncRNA_intronic
CAediting_573909	chr7_92673987_-	ncRNA_intronic
CAediting_573910	chr7_92674892_-	ncRNA_intronic
CAediting_573911	chr7_92674900_-	ncRNA_intronic
CAediting_573912	chr7_92674970_-	ncRNA_intronic
CAediting_573913	chr7_92674996_-	ncRNA_intronic
CAediting_573914	chr7_92675004_-	ncRNA_intronic
CAediting_573915	chr7_92675037_-	ncRNA_intronic
CAediting_573916	chr7_92677425_-	ncRNA_intronic
CAediting_573917	chr7_92677497_-	ncRNA_intronic
CAediting_573918	chr7_92677543_-	ncRNA_intronic
CAediting_573919	chr7_92679817_-	ncRNA_intronic
CAediting_573920	chr7_92679841_-	ncRNA_intronic
CAediting_573921	chr7_92679946_-	ncRNA_intronic
CAediting_573922	chr7_92679978_-	ncRNA_intronic
CAediting_573923	chr7_92692657_-	ncRNA_intronic
CAediting_573924	chr7_92702348_-	ncRNA_intronic
CAediting_573925	chr7_92702397_-	ncRNA_intronic
CAediting_573926	chr7_92702415_-	ncRNA_intronic
CAediting_573927	chr7_92702519_-	ncRNA_intronic
CAediting_573928	chr7_92711613_-	ncRNA_intronic
CAediting_573929	chr7_92711660_-	ncRNA_intronic
CAediting_573930	chr7_92711675_-	ncRNA_intronic
CAediting_573931	chr7_92711732_-	ncRNA_intronic
CAediting_573932	chr7_92711735_-	ncRNA_intronic
CAediting_573933	chr7_92711736_-	ncRNA_intronic
CAediting_573934	chr7_92711737_-	ncRNA_intronic
CAediting_573935	chr7_92711740_-	ncRNA_intronic
CAediting_573936	chr7_92711744_-	ncRNA_intronic
CAediting_573937	chr7_92711745_-	ncRNA_intronic
CAediting_573938	chr7_92711747_-	ncRNA_intronic
CAediting_573939	chr7_92711750_-	ncRNA_intronic
CAediting_573940	chr7_92711761_-	ncRNA_intronic
CAediting_573941	chr7_92711762_-	ncRNA_intronic
CAediting_573942	chr7_92711763_-	ncRNA_intronic
CAediting_573943	chr7_92711764_-	ncRNA_intronic
CAediting_573944	chr7_92711766_-	ncRNA_intronic
CAediting_573945	chr7_92711771_-	ncRNA_intronic
CAediting_573946	chr7_92711772_-	ncRNA_intronic
CAediting_573947	chr7_92711792_-	ncRNA_intronic
CAediting_573948	chr7_92711994_-	ncRNA_intronic
CAediting_573949	chr7_92711995_-	ncRNA_intronic
CAediting_573950	chr7_92711999_-	ncRNA_intronic
CAediting_573951	chr7_92712007_-	ncRNA_intronic
CAediting_573952	chr7_92712014_-	ncRNA_intronic
CAediting_573953	chr7_92712024_-	ncRNA_intronic
CAediting_573954	chr7_92712030_-	ncRNA_intronic
CAediting_573955	chr7_92712039_-	ncRNA_intronic
CAediting_573956	chr7_92712040_-	ncRNA_intronic
CAediting_573957	chr7_92712073_-	ncRNA_intronic
CAediting_573958	chr7_92712076_-	ncRNA_intronic
CAediting_573959	chr7_92712097_-	ncRNA_intronic
CAediting_573960	chr7_92712098_-	ncRNA_intronic
CAediting_573961	chr7_92712103_-	ncRNA_intronic
CAediting_573962	chr7_92712122_-	ncRNA_intronic
CAediting_573963	chr7_92713019_-	ncRNA_intronic
CAediting_573964	chr7_92713108_-	ncRNA_intronic
CAediting_573965	chr7_92713131_-	ncRNA_intronic
CAediting_573966	chr7_92723076_-	ncRNA_intronic
CAediting_573967	chr7_92726522_-	intronic
CAediting_573968	chr7_92726570_-	intronic
CAediting_573969	chr7_92726610_-	intronic
CAediting_573970	chr7_92729838_-	intronic
CAediting_573971	chr7_92729845_-	intronic
CAediting_573972	chr7_92729850_-	intronic
CAediting_573973	chr7_92729878_-	intronic
CAediting_573974	chr7_92729884_-	intronic
CAediting_573975	chr7_92729888_-	intronic
CAediting_573976	chr7_92729891_-	intronic
CAediting_573977	chr7_92729896_-	intronic
CAediting_573978	chr7_92729904_-	intronic
CAediting_573979	chr7_92729959_-	intronic
CAediting_573980	chr7_92730023_-	intronic
CAediting_573981	chr7_92732201_-	intronic
CAediting_573982	chr7_92732226_-	intronic
CAediting_573983	chr7_92732272_-	intronic
CAediting_573984	chr7_92733971_-	intronic
CAediting_573985	chr7_92738448_-	intronic
CAediting_573986	chr7_92738530_-	intronic
CAediting_573987	chr7_92739909_-	intronic
CAediting_573988	chr7_92739958_-	intronic
CAediting_573989	chr7_92740009_-	intronic
CAediting_573990	chr7_92740037_-	intronic
CAediting_573991	chr7_92740053_-	intronic
CAediting_573992	chr7_92753156_-	intronic
CAediting_573993	chr7_92753189_-	intronic
CAediting_573994	chr7_92762732_-	intronic
CAediting_573995	chr7_92762792_-	intronic
CAediting_573996	chr7_92767031_-	intronic
CAediting_573997	chr7_92767049_-	intronic
CAediting_573998	chr7_92767050_-	intronic
CAediting_573999	chr7_92767079_-	intronic
CAediting_574000	chr7_92767082_-	intronic
CAediting_574001	chr7_92767083_-	intronic
CAediting_574002	chr7_92767088_-	intronic
CAediting_574003	chr7_92767089_-	intronic
CAediting_574004	chr7_92767090_-	intronic
CAediting_574005	chr7_92767091_-	intronic
CAediting_574006	chr7_92767094_-	intronic
CAediting_574007	chr7_92767100_-	intronic
CAediting_574008	chr7_92767105_-	intronic
CAediting_574009	chr7_92767106_-	intronic
CAediting_574010	chr7_92767123_-	intronic
CAediting_574011	chr7_92767124_-	intronic
CAediting_574012	chr7_92767140_-	intronic
CAediting_574013	chr7_92768065_-	intronic
CAediting_574014	chr7_92768081_-	intronic
CAediting_574015	chr7_92768093_-	intronic
CAediting_574016	chr7_92768105_-	intronic
CAediting_574017	chr7_92770974_-	intronic
CAediting_574018	chr7_92771074_-	intronic
CAediting_574019	chr7_92801838_-	intronic
CAediting_574020	chr7_92811896_-	intronic
CAediting_574021	chr7_92811908_-	intronic
CAediting_574022	chr7_92811931_-	intronic
CAediting_574023	chr7_92811969_-	intronic
CAediting_574024	chr7_92811971_-	intronic
CAediting_574025	chr7_92811988_-	intronic
CAediting_574026	chr7_92812137_-	intronic
CAediting_574027	chr7_92812510_-	intronic
CAediting_574028	chr7_92812649_-	intronic
CAediting_574029	chr7_92812653_-	intronic
CAediting_574030	chr7_92812658_-	intronic
CAediting_574031	chr7_92812698_-	intronic
CAediting_574032	chr7_92812699_-	intronic
CAediting_574033	chr7_92812707_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_573866	chr7_92630102_-	LTR	ERVL-MaLR	MLT1A
CAediting_573867	chr7_92651018_-	SINE	Alu	AluSx
CAediting_573868	chr7_92657994_-	SINE	Alu	AluJb
CAediting_573869	chr7_92663442_-	SINE	Alu	AluSx3
CAediting_573870	chr7_92663448_-	SINE	Alu	AluSx3
CAediting_573871	chr7_92663457_-	SINE	Alu	AluSx3
CAediting_573872	chr7_92663538_-	SINE	Alu	AluSx3
CAediting_573873	chr7_92663543_-	SINE	Alu	AluSx3
CAediting_573874	chr7_92663573_-	SINE	Alu	AluSx3
CAediting_573875	chr7_92663579_-	SINE	Alu	AluSx3
CAediting_573876	chr7_92663615_-	SINE	Alu	AluSx3
CAediting_573877	chr7_92663618_-	SINE	Alu	AluSx3
CAediting_573879	chr7_92664878_-	SINE	Alu	AluSc8
CAediting_573880	chr7_92664882_-	SINE	Alu	AluSc8
CAediting_573881	chr7_92664897_-	SINE	Alu	AluSc8
CAediting_573882	chr7_92664914_-	SINE	Alu	AluSc8
CAediting_573883	chr7_92664924_-	SINE	Alu	AluSc8
CAediting_573884	chr7_92664934_-	SINE	Alu	AluSc8
CAediting_573885	chr7_92664950_-	SINE	Alu	AluSc8
CAediting_573886	chr7_92664953_-	SINE	Alu	AluSc8
CAediting_573887	chr7_92664954_-	SINE	Alu	AluSc8
CAediting_573888	chr7_92664955_-	SINE	Alu	AluSc8
CAediting_573889	chr7_92664956_-	SINE	Alu	AluSc8
CAediting_573890	chr7_92664957_-	SINE	Alu	AluSc8
CAediting_573891	chr7_92664958_-	SINE	Alu	AluSc8
CAediting_573892	chr7_92664962_-	SINE	Alu	AluSc8
CAediting_573893	chr7_92664964_-	SINE	Alu	AluSc8
CAediting_573894	chr7_92664980_-	SINE	Alu	AluSc8
CAediting_573895	chr7_92665006_-	SINE	Alu	AluSc8
CAediting_573896	chr7_92665049_-	SINE	Alu	AluSc8
CAediting_573897	chr7_92665052_-	SINE	Alu	AluSc8
CAediting_573898	chr7_92665057_-	SINE	Alu	AluSc8
CAediting_573899	chr7_92665058_-	SINE	Alu	AluSc8
CAediting_573900	chr7_92665064_-	SINE	Alu	AluSc8
CAediting_573902	chr7_92667336_-	SINE	Alu	AluJr4
CAediting_573903	chr7_92667416_-	SINE	Alu	AluJr4
CAediting_573904	chr7_92667422_-	SINE	Alu	AluJr4
CAediting_573905	chr7_92667425_-	SINE	Alu	AluJr4
CAediting_573906	chr7_92667720_-	SINE	Alu	AluJb
CAediting_573907	chr7_92673942_-	SINE	Alu	AluSx
CAediting_573908	chr7_92673948_-	SINE	Alu	AluSx
CAediting_573909	chr7_92673987_-	SINE	Alu	AluSx
CAediting_573910	chr7_92674892_-	SINE	Alu	AluSz6
CAediting_573911	chr7_92674900_-	SINE	Alu	AluSz6
CAediting_573912	chr7_92674970_-	SINE	Alu	AluSz6
CAediting_573913	chr7_92674996_-	SINE	Alu	AluSz6
CAediting_573914	chr7_92675004_-	SINE	Alu	AluSz6
CAediting_573915	chr7_92675037_-	SINE	Alu	AluSz6
CAediting_573916	chr7_92677425_-	SINE	Alu	AluSz
CAediting_573917	chr7_92677497_-	SINE	Alu	AluSz
CAediting_573918	chr7_92677543_-	SINE	Alu	AluSz
CAediting_573919	chr7_92679817_-	SINE	Alu	AluSz
CAediting_573920	chr7_92679841_-	SINE	Alu	AluSz
CAediting_573921	chr7_92679946_-	SINE	Alu	AluSz
CAediting_573922	chr7_92679978_-	SINE	Alu	AluSz
CAediting_573923	chr7_92692657_-	SINE	Alu	AluJb
CAediting_573924	chr7_92702348_-	SINE	Alu	AluSx
CAediting_573925	chr7_92702397_-	SINE	Alu	AluSx
CAediting_573926	chr7_92702415_-	SINE	Alu	AluSx
CAediting_573927	chr7_92702519_-	SINE	Alu	AluSx
CAediting_573928	chr7_92711613_-	SINE	Alu	AluJb
CAediting_573929	chr7_92711660_-	SINE	Alu	AluJb
CAediting_573930	chr7_92711675_-	SINE	Alu	AluJb
CAediting_573931	chr7_92711732_-	SINE	Alu	AluJb
CAediting_573932	chr7_92711735_-	SINE	Alu	AluJb
CAediting_573933	chr7_92711736_-	SINE	Alu	AluJb
CAediting_573934	chr7_92711737_-	SINE	Alu	AluJb
CAediting_573935	chr7_92711740_-	SINE	Alu	AluJb
CAediting_573936	chr7_92711744_-	SINE	Alu	AluJb
CAediting_573937	chr7_92711745_-	SINE	Alu	AluJb
CAediting_573938	chr7_92711747_-	SINE	Alu	AluJb
CAediting_573939	chr7_92711750_-	SINE	Alu	AluJb
CAediting_573940	chr7_92711761_-	SINE	Alu	AluJb
CAediting_573941	chr7_92711762_-	SINE	Alu	AluJb
CAediting_573942	chr7_92711763_-	SINE	Alu	AluJb
CAediting_573943	chr7_92711764_-	SINE	Alu	AluJb
CAediting_573944	chr7_92711766_-	SINE	Alu	AluJb
CAediting_573945	chr7_92711771_-	SINE	Alu	AluJb
CAediting_573946	chr7_92711772_-	SINE	Alu	AluJb
CAediting_573947	chr7_92711792_-	SINE	Alu	AluJb
CAediting_573948	chr7_92711994_-	SINE	Alu	AluYk4
CAediting_573949	chr7_92711995_-	SINE	Alu	AluYk4
CAediting_573950	chr7_92711999_-	SINE	Alu	AluYk4
CAediting_573951	chr7_92712007_-	SINE	Alu	AluYk4
CAediting_573952	chr7_92712014_-	SINE	Alu	AluYk4
CAediting_573953	chr7_92712024_-	SINE	Alu	AluYk4
CAediting_573954	chr7_92712030_-	SINE	Alu	AluYk4
CAediting_573955	chr7_92712039_-	SINE	Alu	AluYk4
CAediting_573956	chr7_92712040_-	SINE	Alu	AluYk4
CAediting_573957	chr7_92712073_-	SINE	Alu	AluYk4
CAediting_573958	chr7_92712076_-	SINE	Alu	AluYk4
CAediting_573959	chr7_92712097_-	SINE	Alu	AluYk4
CAediting_573960	chr7_92712098_-	SINE	Alu	AluYk4
CAediting_573961	chr7_92712103_-	SINE	Alu	AluYk4
CAediting_573962	chr7_92712122_-	SINE	Alu	AluYk4
CAediting_573963	chr7_92713019_-	SINE	Alu	AluSx4
CAediting_573964	chr7_92713108_-	SINE	Alu	AluSx4
CAediting_573965	chr7_92713131_-	SINE	Alu	AluSx4
CAediting_573966	chr7_92723076_-	SINE	Alu	AluSz6
CAediting_573967	chr7_92726522_-	SINE	Alu	AluJb
CAediting_573968	chr7_92726570_-	SINE	Alu	AluJb
CAediting_573969	chr7_92726610_-	SINE	Alu	AluJb
CAediting_573970	chr7_92729838_-	SINE	Alu	AluJr4
CAediting_573971	chr7_92729845_-	SINE	Alu	AluJr4
CAediting_573972	chr7_92729850_-	SINE	Alu	AluJr4
CAediting_573973	chr7_92729878_-	SINE	Alu	AluJr4
CAediting_573974	chr7_92729884_-	SINE	Alu	AluJr4
CAediting_573975	chr7_92729888_-	SINE	Alu	AluJr4
CAediting_573976	chr7_92729891_-	SINE	Alu	AluJr4
CAediting_573977	chr7_92729896_-	SINE	Alu	AluJr4
CAediting_573978	chr7_92729904_-	SINE	Alu	AluJr4
CAediting_573979	chr7_92729959_-	SINE	Alu	AluJr4
CAediting_573980	chr7_92730023_-	SINE	Alu	AluJr4
CAediting_573981	chr7_92732201_-	SINE	Alu	AluJb
CAediting_573982	chr7_92732226_-	SINE	Alu	AluJb
CAediting_573983	chr7_92732272_-	SINE	Alu	AluJb
CAediting_573984	chr7_92733971_-	SINE	Alu	FLAM_A
CAediting_573985	chr7_92738448_-	SINE	Alu	AluSq
CAediting_573986	chr7_92738530_-	SINE	Alu	AluSq
CAediting_573987	chr7_92739909_-	SINE	Alu	AluJo
CAediting_573988	chr7_92739958_-	SINE	Alu	AluJo
CAediting_573989	chr7_92740009_-	SINE	Alu	AluJo
CAediting_573990	chr7_92740037_-	SINE	Alu	AluJo
CAediting_573991	chr7_92740053_-	SINE	Alu	AluJo
CAediting_573994	chr7_92762732_-	SINE	Alu	AluSx3
CAediting_573995	chr7_92762792_-	SINE	Alu	AluSx3
CAediting_574017	chr7_92770974_-	SINE	Alu	AluSg
CAediting_574018	chr7_92771074_-	SINE	Alu	AluSg
CAediting_574019	chr7_92801838_-	SINE	Alu	AluSz
CAediting_574020	chr7_92811896_-	SINE	Alu	AluSg
CAediting_574021	chr7_92811908_-	SINE	Alu	AluSg
CAediting_574022	chr7_92811931_-	SINE	Alu	AluSg
CAediting_574023	chr7_92811969_-	SINE	Alu	AluSg
CAediting_574024	chr7_92811971_-	SINE	Alu	AluSg
CAediting_574025	chr7_92811988_-	SINE	Alu	AluSg
CAediting_574026	chr7_92812137_-	SINE	Alu	AluSg
CAediting_574027	chr7_92812510_-	SINE	Alu	AluJr
CAediting_574028	chr7_92812649_-	SINE	Alu	AluJr
CAediting_574029	chr7_92812653_-	SINE	Alu	AluJr
CAediting_574030	chr7_92812658_-	SINE	Alu	AluJr
CAediting_574031	chr7_92812698_-	SINE	Alu	AluJr
CAediting_574032	chr7_92812699_-	SINE	Alu	AluJr
CAediting_574033	chr7_92812707_-	SINE	Alu	AluJr

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RNA A-to-I editing events in the alternative splicing sites for CDK6

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000105810.8.CDK6.

Correlation between RNA A-to-I editing and PSI for ENSG00000105810.8.CDK6.

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for CDK6

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Top

Protein coding region RNA A-to-I editings for CDK6

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for CDK6

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000105810.8	ENST00000265734	hsa-miR-605-3p	92607252	92607259	8mer-1a	92607252	92607272	150	-15.29
CAediting_748296	chr10_51299626_+	ENSG00000105810.8	ENST00000265734	hsa-miR-605-3p	92607218	92607224	7mer-m8	92607217	92607238	159	-20.29
CAediting_748296	chr10_51299626_+	ENSG00000105810.8	ENST00000265734	hsa-miR-605-3p	92605780	92605786	7mer-m8	92605779	92605803	141	-19.27
CAediting_980496	chr14_31014685_-	ENSG00000105810.8	ENST00000265734	hsa-miR-624-3p	92608613	92608618	6mer	92608612	92608633	142	-22.75
CAediting_980496	chr14_31014685_-	ENSG00000105810.8	ENST00000265734	hsa-miR-624-3p	92605841	92605847	7mer-m8	92605840	92605860	140	-18.86
CAediting_393	chr1_1167164_+	ENSG00000105810.8	ENST00000265734	hsa-miR-200b-3p	92612989	92612995	7mer-m8	92612988	92613009	148	-11.13
CAediting_393	chr1_1167164_+	ENSG00000105810.8	ENST00000265734	hsa-miR-200b-3p	92612733	92612739	7mer-m8	92612732	92612753	140	-9.4
CAediting_393	chr1_1167164_+	ENSG00000105810.8	ENST00000265734	hsa-miR-200b-3p	92611780	92611786	7mer-m8	92611779	92611800	140	-11.37
CAediting_393	chr1_1167164_+	ENSG00000105810.8	ENST00000265734	hsa-miR-200b-3p	92610356	92610362	7mer-m8	92610355	92610376	143	-8.97
CAediting_393	chr1_1167164_+	ENSG00000105810.8	ENST00000265734	hsa-miR-200b-3p	92614529	92614535	7mer-m8	92614528	92614547	143	-13.95
CAediting_688080	chr9_63819626_+	ENSG00000105810.8	ENST00000265734	hsa-miR-4477b	92610655	92610662	8mer-1a	92610655	92610682	155	-16.77
CAediting_1054808	chr15_66496985_-	ENSG00000105810.8	ENST00000265734	hsa-miR-4512	92608830	92608835	6mer	92608829	92608853	147	-39.79
CAediting_1229413	chr17_67471544_+	ENSG00000105810.8	ENST00000265734	hsa-miR-548aa	92612352	92612359	8mer-1a	92612352	92612377	150	-9.35
CAediting_1160181	chr17_7017644_-	ENSG00000105810.8	ENST00000265734	hsa-miR-195-3p	92613145	92613151	7mer-m8	92613144	92613166	158	-14.99
CAediting_1160181	chr17_7017644_-	ENSG00000105810.8	ENST00000265734	hsa-miR-195-3p	92613111	92613117	7mer-m8	92613110	92613130	153	-13.59
CAediting_1160181	chr17_7017644_-	ENSG00000105810.8	ENST00000265734	hsa-miR-195-3p	92613041	92613048	8mer-1a	92613041	92613062	147	-10.69
CAediting_1160181	chr17_7017644_-	ENSG00000105810.8	ENST00000265734	hsa-miR-195-3p	92609625	92609632	8mer-1a	92609625	92609645	154	-16.51
CAediting_86358	chr1_109598906_+	ENSG00000105810.8	ENST00000265734	hsa-miR-197-5p	92608978	92608984	7mer-m8	92608977	92608999	141	-20.57
CAediting_86358	chr1_109598906_+	ENSG00000105810.8	ENST00000265734	hsa-miR-197-5p	92605844	92605850	7mer-m8	92605843	92605865	152	-20.77
CAediting_117844	chr1_162342605_+	ENSG00000105810.8	ENST00000265734	hsa-miR-556-3p	92611149	92611155	7mer-m8	92611148	92611170	145	-9.45
CAediting_228905	chr2_188297554_+	ENSG00000105810.8	ENST00000265734	hsa-miR-561-3p	92611649	92611655	7mer-m8	92611648	92611669	140	-8.32
CAediting_228905	chr2_188297554_+	ENSG00000105810.8	ENST00000265734	hsa-miR-561-3p	92611252	92611258	7mer-m8	92611251	92611272	153	-8.07
CAediting_228905	chr2_188297554_+	ENSG00000105810.8	ENST00000265734	hsa-miR-561-3p	92614146	92614152	7mer-m8	92614145	92614170	154	-13.34
CAediting_442554	chr5_154685830_+	ENSG00000105810.8	ENST00000265734	hsa-miR-1303	92614994	92615000	7mer-m8	92614993	92615016	155	-23.28
CAediting_524911	chr7_5495852_-	ENSG00000105810.8	ENST00000265734	hsa-miR-589-3p	92606006	92606012	7mer-m8	92606005	92606028	140	-13.62
CAediting_524911	chr7_5495852_-	ENSG00000105810.8	ENST00000265734	hsa-miR-589-3p	92605618	92605625	8mer-1a	92605618	92605641	140	-16.98
CAediting_468389	chr6_31355314_-	ENSG00000105810.8	ENST00000265734	hsa-miR-6891-5p	92607265	92607271	7mer-m8	92607264	92607282	140	-17
CAediting_1524209	chrX_134546392_-	ENSG00000105810.8	ENST00000265734	hsa-miR-503-5p	92608888	92608894	7mer-m8	92608887	92608909	143	-18.11

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_442554	chr5_154685830_+	ENSG00000105810.8	ENST00000265734	hsa-miR-1303	92614112	92614118	7mer-m8	92614111	92614132	145	-16.75
CAediting_442554	chr5_154685830_+	ENSG00000105810.8	ENST00000265734	hsa-miR-1303	92613840	92613846	7mer-m8	92613839	92613860	144	-13.57
CAediting_442554	chr5_154685830_+	ENSG00000105810.8	ENST00000265734	hsa-miR-1303	92605643	92605649	7mer-m8	92605642	92605665	155	-15.11
CAediting_1160181	chr17_7017644_-	ENSG00000105810.8	ENST00000265734	hsa-miR-195-3p	92605066	92605072	7mer-m8	92605065	92605086	140	-11.23
CAediting_1160181	chr17_7017644_-	ENSG00000105810.8	ENST00000265734	hsa-miR-195-3p	92612259	92612265	7mer-m8	92612258	92612280	151	-12.07
CAediting_1160181	chr17_7017644_-	ENSG00000105810.8	ENST00000265734	hsa-miR-195-3p	92611463	92611469	7mer-m8	92611462	92611483	140	-4.17
CAediting_1160181	chr17_7017644_-	ENSG00000105810.8	ENST00000265734	hsa-miR-195-3p	92611271	92611277	7mer-m8	92611270	92611291	150	-12.85
CAediting_1160181	chr17_7017644_-	ENSG00000105810.8	ENST00000265734	hsa-miR-195-3p	92606855	92606861	7mer-m8	92606854	92606876	144	-13.4
CAediting_86358	chr1_109598906_+	ENSG00000105810.8	ENST00000265734	hsa-miR-197-5p	92608597	92608603	7mer-m8	92608596	92608618	147	-19.62
CAediting_393	chr1_1167164_+	ENSG00000105810.8	ENST00000265734	hsa-miR-200b-3p	92609229	92609235	7mer-m8	92609228	92609249	145	-9.39
CAediting_1368054	chr19_46709310_-	ENSG00000105810.8	ENST00000265734	hsa-miR-320e	92613892	92613898	7mer-1a	92613892	92613910	143	-15.47
CAediting_604450	chr7_133034877_-	ENSG00000105810.8	ENST00000265734	hsa-miR-3654	92609011	92609017	7mer-m8	92609010	92609028	140	-14.25
CAediting_77128	chr1_85133844_+	ENSG00000105810.8	ENST00000265734	hsa-miR-4423-3p	92611559	92611565	7mer-m8	92611558	92611583	154	-19.5
CAediting_688080	chr9_63819626_+	ENSG00000105810.8	ENST00000265734	hsa-miR-4477b	92606057	92606064	8mer-1a	92606057	92606079	151	-10.14
CAediting_688081	chr9_63819627_+	ENSG00000105810.8	ENST00000265734	hsa-miR-4477b	92606057	92606064	8mer-1a	92606057	92606079	151	-10.14
CAediting_396018	chr5_1062918_-	ENSG00000105810.8	ENST00000265734	hsa-miR-4635	92607716	92607721	6mer	92607715	92607735	143	-19.48
CAediting_1524209	chrX_134546392_-	ENSG00000105810.8	ENST00000265734	hsa-miR-503-5p	92608751	92608756	6mer	92608750	92608770	144	-25.36
CAediting_1229413	chr17_67471544_+	ENSG00000105810.8	ENST00000265734	hsa-miR-548aa	92605447	92605454	8mer-1a	92605447	92605471	149	-5.83
CAediting_1229415	chr17_67471547_+	ENSG00000105810.8	ENST00000265734	hsa-miR-548aa	92605447	92605454	8mer-1a	92605447	92605471	149	-5.83
CAediting_1229414	chr17_67471546_+	ENSG00000105810.8	ENST00000265734	hsa-miR-548aa	92605447	92605454	8mer-1a	92605447	92605471	149	-5.83
CAediting_117844	chr1_162342605_+	ENSG00000105810.8	ENST00000265734	hsa-miR-556-3p	92607030	92607037	8mer-1a	92607030	92607051	146	-9.13
CAediting_228905	chr2_188297554_+	ENSG00000105810.8	ENST00000265734	hsa-miR-561-3p	92612556	92612561	6mer	92612555	92612576	140	-13.87
CAediting_228905	chr2_188297554_+	ENSG00000105810.8	ENST00000265734	hsa-miR-561-3p	92611621	92611627	7mer-1a	92611621	92611642	154	-11.5
CAediting_228905	chr2_188297554_+	ENSG00000105810.8	ENST00000265734	hsa-miR-561-3p	92609548	92609554	7mer-m8	92609547	92609567	146	-6.61
CAediting_228905	chr2_188297554_+	ENSG00000105810.8	ENST00000265734	hsa-miR-561-3p	92606727	92606733	7mer-m8	92606726	92606746	144	-9.93
CAediting_524911	chr7_5495852_-	ENSG00000105810.8	ENST00000265734	hsa-miR-589-3p	92612752	92612759	8mer-1a	92612752	92612775	152	-17.13
CAediting_524911	chr7_5495852_-	ENSG00000105810.8	ENST00000265734	hsa-miR-589-3p	92609946	92609952	7mer-m8	92609945	92609969	145	-10.54
CAediting_980496	chr14_31014685_-	ENSG00000105810.8	ENST00000265734	hsa-miR-624-3p	92613599	92613604	6mer	92613598	92613618	150	-20.54
CAediting_1351755	chr19_40282625_-	ENSG00000105810.8	ENST00000265734	hsa-miR-641	92605255	92605262	8mer-1a	92605255	92605278	140	-11.82
CAediting_1399425	chr20_1392958_-	ENSG00000105810.8	ENST00000265734	hsa-miR-6869-5p	92612970	92612977	8mer-1a	92612970	92612991	140	-13.72
CAediting_468389	chr6_31355314_-	ENSG00000105810.8	ENST00000265734	hsa-miR-6891-5p	92611970	92611976	7mer-m8	92611969	92611988	152	-26.01

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CDK6

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000265734.7	protein_coding

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_573865	ENST00000265734.7	chr7_92613435_-	-3157.90	-3151.70	-3157.90

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Relation with ADAR for CDK6

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LAML	CAediting_573933	chr7_92711736_-	.	.	.	.	0.00150915696382075	0.410654741504421

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Relation with cancer stages for CDK6

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for CDK6

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for CDK6

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
CDK6	Q00534	DB09073	Palbociclib	Cyclin-dependent kinase 6	SmallMoleculeDrug	approved\|investigational
CDK6	Q00534	DB11730	Ribociclib	Cyclin-dependent kinase 6	SmallMoleculeDrug	approved\|investigational
CDK6	Q00534	DB12001	Abemaciclib	Cyclin-dependent kinase 6	SmallMoleculeDrug	approved\|investigational

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RelatedDiseases for CDK6

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
CDK6	C0004238	Atrial Fibrillation	2	CTD_human
CDK6	C0025149	Medulloblastoma	2	CTD_human
CDK6	C0205833	Medullomyoblastoma	2	CTD_human
CDK6	C0235480	Paroxysmal atrial fibrillation	2	CTD_human
CDK6	C0278510	Childhood Medulloblastoma	2	CTD_human
CDK6	C0278876	Adult Medulloblastoma	2	CTD_human
CDK6	C0751291	Desmoplastic Medulloblastoma	2	CTD_human
CDK6	C1275668	Melanotic medulloblastoma	2	CTD_human
CDK6	C2585653	Persistent atrial fibrillation	2	CTD_human
CDK6	C3468561	familial atrial fibrillation	2	CTD_human
CDK6	C0002871	Anemia	1	CTD_human
CDK6	C0003873	Rheumatoid Arthritis	1	CTD_human
CDK6	C0004403	Autosome Abnormalities	1	CTD_human
CDK6	C0008625	Chromosome Aberrations	1	CTD_human
CDK6	C0017636	Glioblastoma	1	CTD_human
CDK6	C0023452	Childhood Acute Lymphoblastic Leukemia	1	CTD_human
CDK6	C0023453	L2 Acute Lymphoblastic Leukemia	1	CTD_human
CDK6	C0023467	Leukemia, Myelocytic, Acute	1	CTD_human
CDK6	C0024668	Mammary Neoplasms, Experimental	1	CTD_human
CDK6	C0026998	Acute Myeloid Leukemia, M1	1	CTD_human
CDK6	C0038454	Cerebrovascular accident	1	CTD_human
CDK6	C0263454	Chloracne	1	CTD_human
CDK6	C0334588	Giant Cell Glioblastoma	1	CTD_human
CDK6	C0345967	Malignant mesothelioma	1	CTD_human
CDK6	C0677866	Brain Stem Neoplasms	1	CTD_human
CDK6	C0751886	Brain Stem Neoplasms, Primary	1	CTD_human
CDK6	C0751887	Medullary Neoplasms	1	CTD_human
CDK6	C0751888	Mesencephalic Neoplasms	1	CTD_human
CDK6	C0751889	Pontine Tumors	1	CTD_human
CDK6	C0751956	Acute Cerebrovascular Accidents	1	CTD_human
CDK6	C1168401	Squamous cell carcinoma of the head and neck	1	CTD_human
CDK6	C1621958	Glioblastoma Multiforme	1	CTD_human
CDK6	C1879321	Acute Myeloid Leukemia (AML-M2)	1	CTD_human
CDK6	C1961102	Precursor Cell Lymphoblastic Leukemia Lymphoma	1	CTD_human
CDK6	C3711387	Autosomal Recessive Primary Microcephaly	1	ORPHANET
CDK6	C4015156	MICROCEPHALY 12, PRIMARY, AUTOSOMAL RECESSIVE	1	CTD_human;GENOMICS_ENGLAND;UNIPROT

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene