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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: PPT2-EGFL8 (CAeditome ID:100532746)

Gene summary for PPT2-EGFL8

check button Gene summary
Gene informationGene symbol

PPT2-EGFL8

Gene ID

100532746

Gene namePPT2-EGFL8 readthrough (NMD candidate)
SynonymsPPT-2|PPT2
Cytomap

6p21.32

Type of genencRNA
DescriptionLysosomal thioesterase PPT2S-thioesterase G14
Modification date20210518
UniProtAcc

.

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for PPT2-EGFL8

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000258388.6
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_469229(32157050, +), CAediting_469230(32157101, +), CAediting_469231(32157295, +), CAediting_469232(32157418, +), CAediting_469233(32157448, +), CAediting_469234(32157474, +), CAediting_469235(32157475, +), CAediting_469236(32157487, +), CAediting_469237(32159171, +), CAediting_469238(32159180, +), CAediting_469239(32159248, +), CAediting_469240(32159258, +), CAediting_469241(32159273, +), CAediting_469242(32159275, +), CAediting_469243(32159278, +), CAediting_469244(32159313, +), CAediting_469245(32159322, +), CAediting_469246(32159770, +), CAediting_469247(32159780, +), CAediting_469248(32159886, +), CAediting_469249(32159905, +), CAediting_469250(32160743, +), CAediting_469251(32160744, +), CAediting_469252(32160809, +), CAediting_469253(32160841, +), CAediting_469254(32160877, +), CAediting_469255(32160908, +), CAediting_469256(32160913, +), CAediting_469257(32160921, +), CAediting_469258(32160922, +), CAediting_469259(32161321, +), CAediting_469260(32161353, +), CAediting_469261(32161370, +), CAediting_469262(32161383, +), CAediting_469263(32161419, +), CAediting_469264(32161758, +), CAediting_469265(32161793, +), CAediting_469266(32161858, +), CAediting_469267(32161915, +), CAediting_469268(32162270, +), CAediting_469269(32162294, +), CAediting_469270(32162300, +), CAediting_469271(32162306, +), CAediting_469272(32162320, +), CAediting_469273(32162324, +), CAediting_469274(32162327, +), CAediting_469275(32162349, +), CAediting_469276(32162417, +), CAediting_469277(32162420, +), CAediting_469278(32162429, +), CAediting_469279(32162482, +), CAediting_469280(32164933, +), CAediting_469281(32164937, +), CAediting_469282(32164955, +), CAediting_469283(32164960, +), CAediting_469284(32164976, +), CAediting_469285(32164986, +), CAediting_469286(32165004, +), CAediting_469287(32165011, +), CAediting_469288(32165012, +), CAediting_469289(32165029, +), CAediting_469290(32165041, +), CAediting_469291(32165051, +), CAediting_469292(32165061, +), CAediting_469293(32165094, +), CAediting_469294(32165111, +), CAediting_469295(32165114, +), CAediting_469296(32165123, +), CAediting_469297(32165155, +), CAediting_469298(32165159, +), CAediting_469299(32165164, +), CAediting_469300(32165173, +), CAediting_469301(32165174, +), CAediting_469302(32165186, +), CAediting_469303(32165195, +), CAediting_469304(32165208, +), CAediting_469305(32165272, +), CAediting_469306(32165286, +), CAediting_469307(32165288, +), CAediting_469308(32165295, +), CAediting_469309(32165407, +), CAediting_469310(32165433, +), CAediting_469311(32165439, +), CAediting_469312(32165475, +), CAediting_469313(32165506, +), CAediting_469314(32165514, +), CAediting_469315(32165519, +), CAediting_469316(32165524, +), CAediting_469317(32165528, +), CAediting_469318(32165534, +), CAediting_469319(32165637, +), CAediting_469320(32165641, +), CAediting_469321(32165664, +), CAediting_469322(32165669, +), CAediting_469323(32165686, +), CAediting_469324(32165690, +), CAediting_469325(32165693, +), CAediting_469326(32165695, +), CAediting_469327(32165696, +), CAediting_469328(32165699, +), CAediting_469329(32165704, +), CAediting_469330(32165705, +), CAediting_469331(32165731, +), CAediting_469332(32165735, +), CAediting_469333(32165736, +), CAediting_469334(32165738, +), CAediting_469335(32165739, +), CAediting_469336(32165756, +), CAediting_469337(32165769, +),

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RNA editing positional annotations for PPT2-EGFL8 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_469229chr6_32157050_+ncRNA_intronic
CAediting_469230chr6_32157101_+ncRNA_intronic
CAediting_469231chr6_32157295_+ncRNA_exonic
CAediting_469232chr6_32157418_+ncRNA_exonic
CAediting_469233chr6_32157448_+ncRNA_exonic
CAediting_469234chr6_32157474_+ncRNA_exonic
CAediting_469235chr6_32157475_+ncRNA_exonic
CAediting_469236chr6_32157487_+ncRNA_exonic
CAediting_469237chr6_32159171_+ncRNA_intronic
CAediting_469238chr6_32159180_+ncRNA_intronic
CAediting_469239chr6_32159248_+ncRNA_intronic
CAediting_469240chr6_32159258_+ncRNA_intronic
CAediting_469241chr6_32159273_+ncRNA_intronic
CAediting_469242chr6_32159275_+ncRNA_intronic
CAediting_469243chr6_32159278_+ncRNA_intronic
CAediting_469244chr6_32159313_+ncRNA_intronic
CAediting_469245chr6_32159322_+ncRNA_intronic
CAediting_469246chr6_32159770_+ncRNA_intronic
CAediting_469247chr6_32159780_+ncRNA_intronic
CAediting_469248chr6_32159886_+ncRNA_intronic
CAediting_469249chr6_32159905_+ncRNA_intronic
CAediting_469250chr6_32160743_+ncRNA_intronic
CAediting_469251chr6_32160744_+ncRNA_intronic
CAediting_469252chr6_32160809_+ncRNA_intronic
CAediting_469253chr6_32160841_+ncRNA_intronic
CAediting_469254chr6_32160877_+ncRNA_intronic
CAediting_469255chr6_32160908_+ncRNA_intronic
CAediting_469256chr6_32160913_+ncRNA_intronic
CAediting_469257chr6_32160921_+ncRNA_intronic
CAediting_469258chr6_32160922_+ncRNA_intronic
CAediting_469259chr6_32161321_+ncRNA_intronic
CAediting_469260chr6_32161353_+ncRNA_intronic
CAediting_469261chr6_32161370_+ncRNA_intronic
CAediting_469262chr6_32161383_+ncRNA_intronic
CAediting_469263chr6_32161419_+ncRNA_intronic
CAediting_469264chr6_32161758_+ncRNA_intronic
CAediting_469265chr6_32161793_+ncRNA_intronic
CAediting_469266chr6_32161858_+ncRNA_intronic
CAediting_469267chr6_32161915_+ncRNA_intronic
CAediting_469268chr6_32162270_+ncRNA_intronic
CAediting_469269chr6_32162294_+ncRNA_intronic
CAediting_469270chr6_32162300_+ncRNA_intronic
CAediting_469271chr6_32162306_+ncRNA_intronic
CAediting_469272chr6_32162320_+ncRNA_intronic
CAediting_469273chr6_32162324_+ncRNA_intronic
CAediting_469274chr6_32162327_+ncRNA_intronic
CAediting_469275chr6_32162349_+ncRNA_intronic
CAediting_469276chr6_32162417_+ncRNA_intronic
CAediting_469277chr6_32162420_+ncRNA_intronic
CAediting_469278chr6_32162429_+ncRNA_intronic
CAediting_469279chr6_32162482_+ncRNA_intronic
CAediting_469280chr6_32164933_+ncRNA_intronic
CAediting_469281chr6_32164937_+ncRNA_intronic
CAediting_469282chr6_32164955_+ncRNA_intronic
CAediting_469283chr6_32164960_+ncRNA_intronic
CAediting_469284chr6_32164976_+ncRNA_intronic
CAediting_469285chr6_32164986_+ncRNA_intronic
CAediting_469286chr6_32165004_+ncRNA_intronic
CAediting_469287chr6_32165011_+ncRNA_intronic
CAediting_469288chr6_32165012_+ncRNA_intronic
CAediting_469289chr6_32165029_+ncRNA_intronic
CAediting_469290chr6_32165041_+ncRNA_intronic
CAediting_469291chr6_32165051_+ncRNA_intronic
CAediting_469292chr6_32165061_+ncRNA_intronic
CAediting_469293chr6_32165094_+ncRNA_intronic
CAediting_469294chr6_32165111_+ncRNA_intronic
CAediting_469295chr6_32165114_+ncRNA_intronic
CAediting_469296chr6_32165123_+ncRNA_intronic
CAediting_469297chr6_32165155_+ncRNA_intronic
CAediting_469298chr6_32165159_+ncRNA_intronic
CAediting_469299chr6_32165164_+ncRNA_intronic
CAediting_469300chr6_32165173_+ncRNA_intronic
CAediting_469301chr6_32165174_+ncRNA_intronic
CAediting_469302chr6_32165186_+ncRNA_intronic
CAediting_469303chr6_32165195_+ncRNA_intronic
CAediting_469304chr6_32165208_+ncRNA_intronic
CAediting_469305chr6_32165272_+ncRNA_exonic
CAediting_469306chr6_32165286_+ncRNA_exonic
CAediting_469307chr6_32165288_+ncRNA_exonic
CAediting_469308chr6_32165295_+ncRNA_exonic
CAediting_469309chr6_32165407_+ncRNA_exonic
CAediting_469310chr6_32165433_+ncRNA_exonic
CAediting_469311chr6_32165439_+ncRNA_exonic
CAediting_469312chr6_32165475_+ncRNA_exonic
CAediting_469313chr6_32165506_+ncRNA_exonic
CAediting_469314chr6_32165514_+ncRNA_exonic
CAediting_469315chr6_32165519_+ncRNA_exonic
CAediting_469316chr6_32165524_+ncRNA_exonic
CAediting_469317chr6_32165528_+ncRNA_exonic
CAediting_469318chr6_32165534_+ncRNA_exonic
CAediting_469319chr6_32165637_+ncRNA_exonic
CAediting_469320chr6_32165641_+ncRNA_exonic
CAediting_469321chr6_32165664_+ncRNA_exonic
CAediting_469322chr6_32165669_+ncRNA_exonic
CAediting_469323chr6_32165686_+ncRNA_exonic
CAediting_469324chr6_32165690_+ncRNA_exonic
CAediting_469325chr6_32165693_+ncRNA_exonic
CAediting_469326chr6_32165695_+ncRNA_exonic
CAediting_469327chr6_32165696_+ncRNA_exonic
CAediting_469328chr6_32165699_+ncRNA_exonic
CAediting_469329chr6_32165704_+ncRNA_exonic
CAediting_469330chr6_32165705_+ncRNA_exonic
CAediting_469331chr6_32165731_+ncRNA_exonic
CAediting_469332chr6_32165735_+ncRNA_exonic
CAediting_469333chr6_32165736_+ncRNA_exonic
CAediting_469334chr6_32165738_+ncRNA_exonic
CAediting_469335chr6_32165739_+ncRNA_exonic
CAediting_469336chr6_32165756_+ncRNA_exonic
CAediting_469337chr6_32165769_+ncRNA_exonic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_469229chr6_32157050_+SINEAluAluSx
CAediting_469230chr6_32157101_+SINEAluAluSx
CAediting_469231chr6_32157295_+SINEAluAluSz
CAediting_469232chr6_32157418_+SINEAluAluSz
CAediting_469233chr6_32157448_+SINEAluAluSz
CAediting_469234chr6_32157474_+SINEAluAluSz
CAediting_469235chr6_32157475_+SINEAluAluSz
CAediting_469236chr6_32157487_+SINEAluAluSz
CAediting_469237chr6_32159171_+SINEAluAluSp
CAediting_469238chr6_32159180_+SINEAluAluSp
CAediting_469239chr6_32159248_+SINEAluAluSp
CAediting_469240chr6_32159258_+SINEAluAluSp
CAediting_469241chr6_32159273_+SINEAluAluSp
CAediting_469242chr6_32159275_+SINEAluAluSp
CAediting_469243chr6_32159278_+SINEAluAluSp
CAediting_469244chr6_32159313_+SINEAluAluSp
CAediting_469245chr6_32159322_+SINEAluAluSp
CAediting_469246chr6_32159770_+SINEAluAluY
CAediting_469247chr6_32159780_+SINEAluAluY
CAediting_469248chr6_32159886_+SINEAluAluY
CAediting_469249chr6_32159905_+SINEAluAluY
CAediting_469250chr6_32160743_+SINEAluAluJb
CAediting_469251chr6_32160744_+SINEAluAluJb
CAediting_469252chr6_32160809_+SINEAluAluJb
CAediting_469253chr6_32160841_+SINEAluAluJb
CAediting_469254chr6_32160877_+SINEAluAluJb
CAediting_469255chr6_32160908_+SINEAluAluJb
CAediting_469256chr6_32160913_+SINEAluAluJb
CAediting_469257chr6_32160921_+SINEAluAluJb
CAediting_469258chr6_32160922_+SINEAluAluJb
CAediting_469259chr6_32161321_+SINEAluAluSq2
CAediting_469260chr6_32161353_+SINEAluAluSq2
CAediting_469261chr6_32161370_+SINEAluAluSq2
CAediting_469262chr6_32161383_+SINEAluAluSq2
CAediting_469263chr6_32161419_+SINEAluAluSq2
CAediting_469264chr6_32161758_+SINEAluAluSx
CAediting_469265chr6_32161793_+SINEAluAluSx
CAediting_469266chr6_32161858_+SINEAluAluSx
CAediting_469267chr6_32161915_+SINEAluAluSx
CAediting_469268chr6_32162270_+SINEAluAluSx1
CAediting_469269chr6_32162294_+SINEAluAluSx1
CAediting_469270chr6_32162300_+SINEAluAluSx1
CAediting_469271chr6_32162306_+SINEAluAluSx1
CAediting_469272chr6_32162320_+SINEAluAluSx1
CAediting_469273chr6_32162324_+SINEAluAluSx1
CAediting_469274chr6_32162327_+SINEAluAluSx1
CAediting_469275chr6_32162349_+SINEAluAluSx1
CAediting_469276chr6_32162417_+SINEAluAluSx1
CAediting_469277chr6_32162420_+SINEAluAluSx1
CAediting_469278chr6_32162429_+SINEAluAluSx1
CAediting_469279chr6_32162482_+SINEAluAluSx1
CAediting_469280chr6_32164933_+SINEAluAluSg4
CAediting_469281chr6_32164937_+SINEAluAluSg4
CAediting_469282chr6_32164955_+SINEAluAluSg4
CAediting_469283chr6_32164960_+SINEAluAluSg4
CAediting_469284chr6_32164976_+SINEAluAluSg4
CAediting_469285chr6_32164986_+SINEAluAluSg4
CAediting_469286chr6_32165004_+SINEAluAluSg4
CAediting_469287chr6_32165011_+SINEAluAluSg4
CAediting_469288chr6_32165012_+SINEAluAluSg4
CAediting_469289chr6_32165029_+SINEAluAluSg4
CAediting_469290chr6_32165041_+SINEAluAluSg4
CAediting_469291chr6_32165051_+SINEAluAluSg4
CAediting_469292chr6_32165061_+SINEAluAluSg4
CAediting_469293chr6_32165094_+SINEAluAluSg4
CAediting_469294chr6_32165111_+SINEAluAluSg4
CAediting_469295chr6_32165114_+SINEAluAluSg4
CAediting_469296chr6_32165123_+SINEAluAluSg4
CAediting_469297chr6_32165155_+SINEAluAluSg4
CAediting_469298chr6_32165159_+SINEAluAluSg4
CAediting_469299chr6_32165164_+SINEAluAluSg4
CAediting_469300chr6_32165173_+SINEAluAluSg4
CAediting_469301chr6_32165174_+SINEAluAluSg4
CAediting_469302chr6_32165186_+SINEAluAluSg4
CAediting_469303chr6_32165195_+SINEAluAluSg4
CAediting_469304chr6_32165208_+SINEAluAluSg4
CAediting_469305chr6_32165272_+SINEAluAluSx1
CAediting_469306chr6_32165286_+SINEAluAluSx1
CAediting_469307chr6_32165288_+SINEAluAluSx1
CAediting_469308chr6_32165295_+SINEAluAluSx1
CAediting_469309chr6_32165407_+SINEAluAluSx1
CAediting_469310chr6_32165433_+SINEAluAluSx1
CAediting_469311chr6_32165439_+SINEAluAluSx1
CAediting_469312chr6_32165475_+SINEAluAluSx1
CAediting_469313chr6_32165506_+SINEAluAluSx1
CAediting_469314chr6_32165514_+SINEAluAluSx1
CAediting_469315chr6_32165519_+SINEAluAluSx1
CAediting_469316chr6_32165524_+SINEAluAluSx1
CAediting_469317chr6_32165528_+SINEAluAluSx1
CAediting_469318chr6_32165534_+SINEAluAluSx1
CAediting_469319chr6_32165637_+SINEAluAluSp
CAediting_469320chr6_32165641_+SINEAluAluSp
CAediting_469321chr6_32165664_+SINEAluAluSp
CAediting_469322chr6_32165669_+SINEAluAluSp
CAediting_469323chr6_32165686_+SINEAluAluSp
CAediting_469324chr6_32165690_+SINEAluAluSp
CAediting_469325chr6_32165693_+SINEAluAluSp
CAediting_469326chr6_32165695_+SINEAluAluSp
CAediting_469327chr6_32165696_+SINEAluAluSp
CAediting_469328chr6_32165699_+SINEAluAluSp
CAediting_469329chr6_32165704_+SINEAluAluSp
CAediting_469330chr6_32165705_+SINEAluAluSp
CAediting_469331chr6_32165731_+SINEAluAluSp
CAediting_469332chr6_32165735_+SINEAluAluSp
CAediting_469333chr6_32165736_+SINEAluAluSp
CAediting_469334chr6_32165738_+SINEAluAluSp
CAediting_469335chr6_32165739_+SINEAluAluSp
CAediting_469336chr6_32165756_+SINEAluAluSp
CAediting_469337chr6_32165769_+SINEAluAluSp

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RNA A-to-I editing events in the alternative splicing sites for PPT2-EGFL8

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000258388.6.PPT2-EGFL8.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000258388.6.PPT2-EGFL8.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PPT2-EGFL8

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for PPT2-EGFL8

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for PPT2-EGFL8

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_393chr1_1167164_+ENSG00000258388.6ENST00000422437hsa-miR-200b-3p32171051321710588mer-1a3217103732171058151-13.23
CAediting_1160181chr17_7017644_-ENSG00000258388.6ENST00000422437hsa-miR-195-3p32169440321694456mer3216942432169446151-19.12
CAediting_86358chr1_109598906_+ENSG00000258388.6ENST00000422437hsa-miR-197-5p32169478321694858mer-1a3216946132169485162-28.62
CAediting_1054808chr15_66496985_-ENSG00000258388.6ENST00000422437hsa-miR-451232170728321707347mer-1a3217071432170734142-25.77
CAediting_1229413chr17_67471544_+ENSG00000258388.6ENST00000422437hsa-miR-548aa32171536321715427mer-m83217151532171543152-20.27
CAediting_1368054chr19_46709310_-ENSG00000258388.6ENST00000422437hsa-miR-320e32170669321706768mer-1a3217066032170676156-22.84
CAediting_1399425chr20_1392958_-ENSG00000258388.6ENST00000422437hsa-miR-6869-5p32170787321707937mer-m83217077332170794144-18.71

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1524209chrX_134546392_-ENSG00000258388.6ENST00000428388hsa-miR-503-5p32167627321676326mer3216761532167636143-20.17
CAediting_1524209chrX_134546392_-ENSG00000258388.6ENST00000428388hsa-miR-503-5p32167630321676356mer3216761532167636143-20.17
CAediting_688081chr9_63819627_+ENSG00000258388.6ENST00000428388hsa-miR-4477b32168180321681867mer-m83216816732168187151-7.85
CAediting_1524209chrX_134546392_-ENSG00000258388.6ENST00000422437hsa-miR-503-5p32167627321676326mer3216761532167636143-20.17
CAediting_1524209chrX_134546392_-ENSG00000258388.6ENST00000422437hsa-miR-503-5p32167630321676356mer3216761532167636143-20.17
CAediting_688080chr9_63819626_+ENSG00000258388.6ENST00000422437hsa-miR-4477b32168180321681867mer-m83216816732168187151-7.85
CAediting_688081chr9_63819627_+ENSG00000258388.6ENST00000422437hsa-miR-4477b32168180321681867mer-m83216816732168187151-7.85
CAediting_86358chr1_109598906_+ENSG00000258388.6ENST00000422437hsa-miR-197-5p32170786321707938mer-1a3217077132170793142-20.91

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for PPT2-EGFL8

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000479001.2retained_intronSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_469231ENST00000479001.2chr6_32157295_+-352.10-352.50-364.10
CAediting_469232ENST00000479001.2chr6_32157418_+-355.60-352.50-364.10
CAediting_469233ENST00000479001.2chr6_32157448_+-357.60-352.50-364.10
CAediting_469234ENST00000479001.2chr6_32157474_+-355.70-352.50-364.10
CAediting_469235ENST00000479001.2chr6_32157475_+-356.00-352.50-364.10
CAediting_469236ENST00000479001.2chr6_32157487_+-352.70-352.50-364.10

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Relation with ADAR for PPT2-EGFL8

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
BRCACAediting_469319chr6_32165637_+....0.01489093350552790.241698273136088
COADCAediting_469333chr6_32165736_+....0.005234595011648420.275858486519377
GBMCAediting_469333chr6_32165736_+....0.02510357968881340.279870946332199
THCACAediting_469333chr6_32165736_+0.02556177687609670.211914325548188....
PCPGCAediting_469333chr6_32165736_+0.0003010965843540420.4112459510528870.04307389108477380.237473452766493..
KIRPCAediting_469336chr6_32165756_+..0.03319301462942440.266632720515319..
SKCMCAediting_469336chr6_32165756_+..0.02948027091798920.293783727524437..

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Relation with cancer stages for PPT2-EGFL8

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
BLCApathologic_stageCAediting_469333chr6_32165736_+0.02709238779858350.192400733751208
BRCApathologic_stageCAediting_469331chr6_32165731_+0.01282862769383190.189406064119053
CESCclinical_stageCAediting_469331chr6_32165731_+0.047117365731767-0.261808177663465
CESCclinical_stageCAediting_469333chr6_32165736_+0.0187679968518904-0.22177935247785
KIRCpathologic_stageCAediting_469331chr6_32165731_+0.001023439677712370.256471065172855
KIRCpathologic_stageCAediting_469335chr6_32165739_+0.003397611637094370.20826634037437
KIRPpathologic_stageCAediting_469333chr6_32165736_+0.001868383451585460.265351632664367

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Relation with survival for PPT2-EGFL8

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
BRCACAediting_469319chr6_32165637_+0.01970913954862540.03582790.000381218

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RelatedDrugs for PPT2-EGFL8

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PPT2-EGFL8

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource