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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

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Relation with survival state

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Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: GIMAP1-GIMAP5 (CAeditome ID:100527949)

Gene summary for GIMAP1-GIMAP5

check button Gene summary
Gene informationGene symbol

GIMAP1-GIMAP5

Gene ID

100527949

Gene nameGIMAP1-GIMAP5 readthrough
Synonyms-
Cytomap

7q36.1

Type of geneprotein-coding
DescriptionGIMAP1-GIMAP5 protein
Modification date20210518
UniProtAcc

.

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for GIMAP1-GIMAP5

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000281887.1
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_611493(150721578, +), CAediting_611494(150721675, +), CAediting_611495(150721677, +), CAediting_611496(150721690, +), CAediting_611497(150721691, +), CAediting_611498(150721731, +), CAediting_611499(150721808, +), CAediting_611500(150721809, +), CAediting_611501(150721810, +), CAediting_611502(150721811, +), CAediting_611503(150721813, +), CAediting_611504(150721815, +), CAediting_611505(150721816, +), CAediting_611506(150742242, +), CAediting_611507(150742258, +), CAediting_611508(150742259, +), CAediting_611509(150742318, +), CAediting_611510(150742360, +), CAediting_611511(150742369, +), CAediting_611512(150742647, +), CAediting_611513(150742876, +), CAediting_611514(150742883, +),

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RNA editing positional annotations for GIMAP1-GIMAP5 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
CAediting_611506chr7_150742242_+nonsynonymous SNVENST00000611999.2c.A715Gp.K239EDDD
CAediting_611510chr7_150742360_+nonsynonymous SNVENST00000611999.2c.A833Gp.N278STDN
CAediting_611512chr7_150742647_+nonsynonymous SNVENST00000611999.2c.A1120Gp.N374DDDD

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_611493chr7_150721578_+UTR3
CAediting_611494chr7_150721675_+UTR3
CAediting_611495chr7_150721677_+UTR3
CAediting_611496chr7_150721690_+UTR3
CAediting_611497chr7_150721691_+UTR3
CAediting_611498chr7_150721731_+UTR3
CAediting_611499chr7_150721808_+UTR3
CAediting_611500chr7_150721809_+UTR3
CAediting_611501chr7_150721810_+UTR3
CAediting_611502chr7_150721811_+UTR3
CAediting_611503chr7_150721813_+UTR3
CAediting_611504chr7_150721815_+UTR3
CAediting_611505chr7_150721816_+UTR3
CAediting_611506chr7_150742242_+exonic
CAediting_611507chr7_150742258_+exonic
CAediting_611508chr7_150742259_+exonic
CAediting_611509chr7_150742318_+exonic
CAediting_611510chr7_150742360_+exonic
CAediting_611511chr7_150742369_+exonic
CAediting_611512chr7_150742647_+exonic
CAediting_611513chr7_150742876_+exonic
CAediting_611514chr7_150742883_+exonic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_611493chr7_150721578_+SINEAluAluSx
CAediting_611494chr7_150721675_+SINEAluAluSx
CAediting_611495chr7_150721677_+SINEAluAluSx
CAediting_611496chr7_150721690_+SINEAluAluSx
CAediting_611497chr7_150721691_+SINEAluAluSx
CAediting_611498chr7_150721731_+SINEAluAluSx
CAediting_611499chr7_150721808_+SINEAluAluSx
CAediting_611500chr7_150721809_+SINEAluAluSx
CAediting_611501chr7_150721810_+SINEAluAluSx
CAediting_611502chr7_150721811_+SINEAluAluSx
CAediting_611503chr7_150721813_+SINEAluAluSx
CAediting_611504chr7_150721815_+SINEAluAluSx
CAediting_611505chr7_150721816_+SINEAluAluSx

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RNA A-to-I editing events in the alternative splicing sites for GIMAP1-GIMAP5

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000281887.1.GIMAP1-GIMAP5.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000281887.1.GIMAP1-GIMAP5.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for GIMAP1-GIMAP5

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for GIMAP1-GIMAP5

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for GIMAP1-GIMAP5

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for GIMAP1-GIMAP5

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000611999.2protein_codingSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_611506ENST00000611999.2chr7_150742242_+-853.10-852.90-860.50
CAediting_611507ENST00000611999.2chr7_150742258_+-852.90-852.90-860.50
CAediting_611508ENST00000611999.2chr7_150742259_+-854.30-852.90-860.50
CAediting_611509ENST00000611999.2chr7_150742318_+-853.40-852.90-860.50
CAediting_611510ENST00000611999.2chr7_150742360_+-853.70-852.90-860.50
CAediting_611511ENST00000611999.2chr7_150742369_+-852.90-852.90-860.50
CAediting_611512ENST00000611999.2chr7_150742647_+-852.90-852.90-860.50
CAediting_611513ENST00000611999.2chr7_150742876_+-853.70-852.90-860.50
CAediting_611514ENST00000611999.2chr7_150742883_+-855.20-852.90-860.50

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Relation with ADAR for GIMAP1-GIMAP5

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
STADCAediting_611502chr7_150721811_+0.04161056948755480.234324012510129....

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Relation with cancer stages for GIMAP1-GIMAP5

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for GIMAP1-GIMAP5

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for GIMAP1-GIMAP5

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for GIMAP1-GIMAP5

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource