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Editing gene: ARHGEF26-AS1 (CAeditome ID:100507524)

Gene summary for ARHGEF26-AS1

Gene summary

Gene information	Gene symbol	ARHGEF26-AS1
	Gene ID	100507524
	Gene name	ARHGEF26 antisense RNA 1
	Synonyms	-
	Cytomap	3q25.2
	Type of gene	ncRNA
	Description	ARHGEF26 antisense RNA 1 (non-protein coding)
	Modification date	20210518
	UniProtAcc	.
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for ARHGEF26-AS1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000243069.6

RNA A-to-I editing events in Cancer.

CAediting_317682(154024628, -), CAediting_317683(154024630, -), CAediting_317684(154024728, -), CAediting_317685(154025764, -), CAediting_317686(154053742, -), CAediting_317687(154053774, -), CAediting_317688(154053781, -), CAediting_317689(154053785, -), CAediting_317690(154053821, -), CAediting_317691(154053826, -), CAediting_317692(154053829, -), CAediting_317693(154053830, -), CAediting_317694(154053835, -), CAediting_317695(154053837, -), CAediting_317696(154053838, -), CAediting_317697(154053839, -), CAediting_317698(154053865, -), CAediting_317699(154053866, -), CAediting_317700(154053867, -), CAediting_317701(154053906, -), CAediting_317702(154053916, -), CAediting_317703(154053949, -), CAediting_317704(154054505, -), CAediting_317705(154090884, -), CAediting_317706(154090889, -), CAediting_317707(154119640, -), CAediting_317708(154119689, -), CAediting_317709(154119699, -), CAediting_317710(154119702, -), CAediting_317711(154119711, -), CAediting_317712(154119724, -), CAediting_317713(154119725, -), CAediting_317714(154119728, -), CAediting_317715(154119729, -), CAediting_317716(154119736, -), CAediting_317717(154119804, -),

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RNA editing positional annotations for ARHGEF26-AS1 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_317682	chr3_154024628_-	ncRNA_exonic
CAediting_317683	chr3_154024630_-	ncRNA_exonic
CAediting_317684	chr3_154024728_-	ncRNA_exonic
CAediting_317685	chr3_154025764_-	ncRNA_exonic
CAediting_317686	chr3_154053742_-	ncRNA_intronic
CAediting_317687	chr3_154053774_-	ncRNA_intronic
CAediting_317688	chr3_154053781_-	ncRNA_intronic
CAediting_317689	chr3_154053785_-	ncRNA_intronic
CAediting_317690	chr3_154053821_-	ncRNA_intronic
CAediting_317691	chr3_154053826_-	ncRNA_intronic
CAediting_317692	chr3_154053829_-	ncRNA_intronic
CAediting_317693	chr3_154053830_-	ncRNA_intronic
CAediting_317694	chr3_154053835_-	ncRNA_intronic
CAediting_317695	chr3_154053837_-	ncRNA_intronic
CAediting_317696	chr3_154053838_-	ncRNA_intronic
CAediting_317697	chr3_154053839_-	ncRNA_intronic
CAediting_317698	chr3_154053865_-	ncRNA_intronic
CAediting_317699	chr3_154053866_-	ncRNA_intronic
CAediting_317700	chr3_154053867_-	ncRNA_intronic
CAediting_317701	chr3_154053906_-	ncRNA_intronic
CAediting_317702	chr3_154053916_-	ncRNA_intronic
CAediting_317703	chr3_154053949_-	ncRNA_intronic
CAediting_317704	chr3_154054505_-	ncRNA_intronic
CAediting_317705	chr3_154090884_-	ncRNA_intronic
CAediting_317706	chr3_154090889_-	ncRNA_intronic
CAediting_317707	chr3_154119640_-	ncRNA_intronic
CAediting_317708	chr3_154119689_-	ncRNA_exonic
CAediting_317709	chr3_154119699_-	ncRNA_exonic
CAediting_317710	chr3_154119702_-	ncRNA_exonic
CAediting_317711	chr3_154119711_-	ncRNA_exonic
CAediting_317712	chr3_154119724_-	ncRNA_exonic
CAediting_317713	chr3_154119725_-	ncRNA_exonic
CAediting_317714	chr3_154119728_-	ncRNA_exonic
CAediting_317715	chr3_154119729_-	ncRNA_exonic
CAediting_317716	chr3_154119736_-	ncRNA_exonic
CAediting_317717	chr3_154119804_-	ncRNA_exonic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_317682	chr3_154024628_-	LINE	L1	L1PA7
CAediting_317683	chr3_154024630_-	LINE	L1	L1PA7
CAediting_317684	chr3_154024728_-	LINE	L1	L1PA7
CAediting_317685	chr3_154025764_-	DNA	TcMar-Tigger	Tigger4a
CAediting_317686	chr3_154053742_-	LINE	L1	L1MEg
CAediting_317687	chr3_154053774_-	LINE	L1	L1MEg
CAediting_317688	chr3_154053781_-	LINE	L1	L1MEg
CAediting_317689	chr3_154053785_-	LINE	L1	L1MEg
CAediting_317690	chr3_154053821_-	LINE	L1	L1MEg
CAediting_317691	chr3_154053826_-	LINE	L1	L1MEg
CAediting_317692	chr3_154053829_-	LINE	L1	L1MEg
CAediting_317693	chr3_154053830_-	LINE	L1	L1MEg
CAediting_317694	chr3_154053835_-	LINE	L1	L1MEg
CAediting_317695	chr3_154053837_-	LINE	L1	L1MEg
CAediting_317696	chr3_154053838_-	LINE	L1	L1MEg
CAediting_317697	chr3_154053839_-	LINE	L1	L1MEg
CAediting_317698	chr3_154053865_-	LINE	L1	L1MEg
CAediting_317699	chr3_154053866_-	LINE	L1	L1MEg
CAediting_317700	chr3_154053867_-	LINE	L1	L1MEg
CAediting_317701	chr3_154053906_-	LINE	L1	L1MEg
CAediting_317702	chr3_154053916_-	LINE	L1	L1MEg
CAediting_317703	chr3_154053949_-	LINE	L1	L1MEg
CAediting_317704	chr3_154054505_-	LINE	L1	L1MEg
CAediting_317705	chr3_154090884_-	SINE	Alu	AluSz
CAediting_317706	chr3_154090889_-	SINE	Alu	AluSz
CAediting_317707	chr3_154119640_-	SINE	Alu	AluSp
CAediting_317708	chr3_154119689_-	SINE	Alu	AluSp
CAediting_317709	chr3_154119699_-	SINE	Alu	AluSp
CAediting_317710	chr3_154119702_-	SINE	Alu	AluSp
CAediting_317711	chr3_154119711_-	SINE	Alu	AluSp
CAediting_317712	chr3_154119724_-	SINE	Alu	AluSp
CAediting_317713	chr3_154119725_-	SINE	Alu	AluSp
CAediting_317714	chr3_154119728_-	SINE	Alu	AluSp
CAediting_317715	chr3_154119729_-	SINE	Alu	AluSp
CAediting_317716	chr3_154119736_-	SINE	Alu	AluSp
CAediting_317717	chr3_154119804_-	SINE	Alu	AluSp

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RNA A-to-I editing events in the alternative splicing sites for ARHGEF26-AS1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000243069.6.ARHGEF26-AS1.

Correlation between RNA A-to-I editing and PSI for ENSG00000243069.6.ARHGEF26-AS1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ARHGEF26-AS1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ARHGEF26-AS1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for ARHGEF26-AS1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1229414	chr17_67471546_+	ENSG00000243069.6	ENST00000621011.2	hsa-miR-548aa	154108953	154108959	7mer-m8	154108952	154108976	152	-9.83
CAediting_442554	chr5_154685830_+	ENSG00000243069.6	ENST00000630930.1	hsa-miR-1303	154084702	154084708	7mer-m8	154084701	154084722	148	-19.34
CAediting_1160181	chr17_7017644_-	ENSG00000243069.6	ENST00000608560.2	hsa-miR-195-3p	154039625	154039631	7mer-m8	154039624	154039645	141	-7.03
CAediting_1229413	chr17_67471544_+	ENSG00000243069.6	ENST00000601822.5	hsa-miR-548aa	154032826	154032832	7mer-m8	154032825	154032848	150	-12.52

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_846604	chr11_93733708_-	ENSG00000243069.6	ENST00000621011.2	hsa-miR-1304-3p	154030364	154030370	7mer-m8	154030363	154108673	141	-16.56
CAediting_228905	chr2_188297554_+	ENSG00000243069.6	ENST00000630930.1	hsa-miR-561-3p	154084940	154084945	6mer	154084939	154084961	151	-14.79
CAediting_442554	chr5_154685830_+	ENSG00000243069.6	ENST00000597231.1	hsa-miR-1303	154028407	154028413	7mer-m8	154028406	154028425	147	-16.03

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ARHGEF26-AS1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000491862.4	antisense
ENST00000467912.4	antisense
ENST00000480639.4	antisense

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_317682	ENST00000491862.4	chr3_154024628_-	-695.00	-695.00	-694.70
CAediting_317683	ENST00000491862.4	chr3_154024630_-	-695.00	-695.00	-694.70
CAediting_317684	ENST00000491862.4	chr3_154024728_-	-694.70	-695.00	-694.70
CAediting_317685	ENST00000491862.4	chr3_154025764_-	-695.00	-695.00	-694.70
CAediting_317708	ENST00000467912.4	chr3_154119689_-	-237.50	-237.50	-244.60
CAediting_317709	ENST00000467912.4	chr3_154119699_-	-236.10	-237.50	-244.60
CAediting_317710	ENST00000467912.4	chr3_154119702_-	-238.20	-237.50	-244.60
CAediting_317711	ENST00000467912.4	chr3_154119711_-	-237.90	-237.50	-244.60
CAediting_317712	ENST00000467912.4	chr3_154119724_-	-240.70	-237.50	-244.60
CAediting_317713	ENST00000467912.4	chr3_154119725_-	-238.60	-237.50	-244.60
CAediting_317714	ENST00000467912.4	chr3_154119728_-	-239.60	-237.50	-244.60
CAediting_317715	ENST00000467912.4	chr3_154119729_-	-237.50	-237.50	-244.60
CAediting_317716	ENST00000467912.4	chr3_154119736_-	-236.80	-237.50	-244.60
CAediting_317708	ENST00000480639.4	chr3_154119689_-	-208.60	-208.70	-218.80
CAediting_317709	ENST00000480639.4	chr3_154119699_-	-209.80	-208.70	-218.80
CAediting_317710	ENST00000480639.4	chr3_154119702_-	-211.30	-208.70	-218.80
CAediting_317711	ENST00000480639.4	chr3_154119711_-	-208.70	-208.70	-218.80
CAediting_317712	ENST00000480639.4	chr3_154119724_-	-210.80	-208.70	-218.80
CAediting_317713	ENST00000480639.4	chr3_154119725_-	-208.70	-208.70	-218.80
CAediting_317714	ENST00000480639.4	chr3_154119728_-	-211.90	-208.70	-218.80
CAediting_317715	ENST00000480639.4	chr3_154119729_-	-208.30	-208.70	-218.80
CAediting_317716	ENST00000480639.4	chr3_154119736_-	-208.00	-208.70	-218.80
CAediting_317717	ENST00000480639.4	chr3_154119804_-	-210.20	-208.70	-218.80

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Relation with ADAR for ARHGEF26-AS1

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for ARHGEF26-AS1

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for ARHGEF26-AS1

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for ARHGEF26-AS1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for ARHGEF26-AS1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene