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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with cancer stages

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Relation with survival state

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Related drugs with this gene

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Related diseases with this gene

Editing gene: CEBPZOS (CAeditome ID:100505876)

Gene summary for CEBPZOS

check button Gene summary
Gene informationGene symbol

CEBPZOS

Gene ID

100505876

Gene nameCEBPZ opposite strand
SynonymsCEBPZ-AS1
Cytomap

2p22.2

Type of geneprotein-coding
Descriptionprotein CEBPZOSCEBPZ antisense RNA 1
Modification date20210518
UniProtAcc

A8MTT3

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for CEBPZOS

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000218739.8

check button RNA A-to-I editing events in Cancer.
CAediting_171018(37197709, +), CAediting_171019(37197999, +), CAediting_171020(37198000, +), CAediting_171021(37198976, +), CAediting_171022(37199056, +), CAediting_171023(37199798, +),

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RNA editing positional annotations for CEBPZOS using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_171018chr2_37197709_+ncRNA_intronic
CAediting_171019chr2_37197999_+ncRNA_intronic
CAediting_171020chr2_37198000_+ncRNA_intronic
CAediting_171021chr2_37198976_+ncRNA_intronic
CAediting_171022chr2_37199056_+ncRNA_intronic
CAediting_171023chr2_37199798_+exonic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_171018chr2_37197709_+SINEAluAluSz
CAediting_171019chr2_37197999_+SINEAluAluSx1
CAediting_171020chr2_37198000_+SINEAluAluSx1
CAediting_171021chr2_37198976_+SINEAluAluJb
CAediting_171022chr2_37199056_+SINEAluAluJb

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RNA A-to-I editing events in the alternative splicing sites for CEBPZOS

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000218739.8.CEBPZOS.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000218739.8.CEBPZOS.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CEBPZOS

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for CEBPZOS

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for CEBPZOS

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_980496chr14_31014685_-ENSG00000218739.8ENST00000397226hsa-miR-624-3p37202468372024747mer-m83720245537202475152-13.11
CAediting_688081chr9_63819627_+ENSG00000218739.8ENST00000397226hsa-miR-4477b37202204372022118mer-1a3720219037202211143-13
CAediting_1368054chr19_46709310_-ENSG00000218739.8ENST00000397064hsa-miR-320e37213570372135778mer-1a3721355937213577147-19.5
CAediting_1229414chr17_67471546_+ENSG00000218739.8ENST00000392061hsa-miR-548aa37204490372044967mer-m83720447337204497140-11.94
CAediting_1229413chr17_67471544_+ENSG00000218739.8ENST00000397226hsa-miR-548aa37202009372020157mer-m83720199237202016150-16.25

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CEBPZOS

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000392061.5protein_codingSoverviewSoverview
ENST00000397064.5protein_codingSoverviewSoverview
ENST00000397226.2protein_codingSoverviewSoverview
ENST00000402297.4protein_codingSoverviewSoverview
ENST00000406711.4protein_codingSoverviewSoverview
ENST00000470216.1retained_intronSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_171023ENST00000392061.5chr2_37199798_+-182.70-181.00-182.70
CAediting_171023ENST00000397064.5chr2_37199798_+-167.30-165.60-167.30
CAediting_171023ENST00000397226.2chr2_37199798_+-424.30-422.60-424.30
CAediting_171023ENST00000402297.4chr2_37199798_+-1009.80-1008.10-1009.80
CAediting_171023ENST00000406711.4chr2_37199798_+-140.40-138.70-140.40
CAediting_171023ENST00000470216.1chr2_37199798_+-179.20-179.50-179.20

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Relation with ADAR for CEBPZOS

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for CEBPZOS

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for CEBPZOS

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for CEBPZOS

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CEBPZOS

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource