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Center for Computational Systems Medicine
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Gene summary

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RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with cancer stages

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Relation with survival state

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Related drugs with this gene

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Related diseases with this gene

Editing gene: IGHV3OR16-13 (CAeditome ID:100287372)

Gene summary for IGHV3OR16-13

check button Gene summary
Gene informationGene symbol

IGHV3OR16-13

Gene ID

100287372

Gene nameimmunoglobulin heavy variable 3/OR16-13 (non-functional)
SynonymsIGHV3OR1613
Cytomap

16p11.2

Type of genepseudo
DescriptionIGHV3/OR16-13
Modification date20210518
UniProtAcc

.

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for IGHV3OR16-13

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000271178.1
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_1113721(33827492, +), CAediting_1113722(33827516, +), CAediting_1113723(33827519, +), CAediting_1113724(33827520, +), CAediting_1113725(33827522, +), CAediting_1113726(33827526, +), CAediting_1113727(33827531, +), CAediting_1113728(33827534, +), CAediting_1113729(33827537, +), CAediting_1113730(33827539, +), CAediting_1113731(33827540, +), CAediting_1113732(33827548, +), CAediting_1113733(33827550, +), CAediting_1113734(33827558, +), CAediting_1113735(33827559, +), CAediting_1113736(33827565, +), CAediting_1113737(33827566, +), CAediting_1113738(33827585, +), CAediting_1113739(33827592, +), CAediting_1113740(33827594, +),

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RNA editing positional annotations for IGHV3OR16-13 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1113721chr16_33827492_+exonic
CAediting_1113722chr16_33827516_+exonic
CAediting_1113723chr16_33827519_+exonic
CAediting_1113724chr16_33827520_+exonic
CAediting_1113725chr16_33827522_+exonic
CAediting_1113726chr16_33827526_+exonic
CAediting_1113727chr16_33827531_+exonic
CAediting_1113728chr16_33827534_+exonic
CAediting_1113729chr16_33827537_+exonic
CAediting_1113730chr16_33827539_+exonic
CAediting_1113731chr16_33827540_+exonic
CAediting_1113732chr16_33827548_+exonic
CAediting_1113733chr16_33827550_+exonic
CAediting_1113734chr16_33827558_+exonic
CAediting_1113735chr16_33827559_+exonic
CAediting_1113736chr16_33827565_+exonic
CAediting_1113737chr16_33827566_+exonic
CAediting_1113738chr16_33827585_+exonic
CAediting_1113739chr16_33827592_+exonic
CAediting_1113740chr16_33827594_+exonic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name

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RNA A-to-I editing events in the alternative splicing sites for IGHV3OR16-13

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000271178.1.IGHV3OR16-13.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000271178.1.IGHV3OR16-13.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for IGHV3OR16-13

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for IGHV3OR16-13

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for IGHV3OR16-13

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for IGHV3OR16-13

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for IGHV3OR16-13

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for IGHV3OR16-13

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for IGHV3OR16-13

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for IGHV3OR16-13

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for IGHV3OR16-13

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource