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Editing gene: CYP4F30P (CAeditome ID:100132708)

Gene summary for CYP4F30P

Gene summary

Gene information	Gene symbol	CYP4F30P
	Gene ID	100132708
	Gene name	cytochrome P450 family 4 subfamily F member 30, pseudogene
	Synonyms	C2orf14
	Cytomap	2q21.1
	Type of gene	pseudo
	Description	4F-se9[6:7:8]cytochrome P450, family 4, subfamily F, polypeptide 30, pseudogene
	Modification date	20210518
	UniProtAcc	.
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for CYP4F30P

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000214081.6

RNA A-to-I editing events in Cancer.

CAediting_213063(130685486, +), CAediting_213064(130685509, +), CAediting_213065(130685516, +), CAediting_213066(130685544, +), CAediting_213067(130685565, +), CAediting_213068(130685569, +), CAediting_213069(130685582, +), CAediting_213070(130685591, +), CAediting_213071(130685594, +), CAediting_213072(130685630, +), CAediting_213073(130685637, +), CAediting_213074(130685645, +), CAediting_213075(130685648, +), CAediting_213076(130685665, +), CAediting_213077(130685674, +), CAediting_213078(130685717, +), CAediting_213079(130685725, +), CAediting_213080(130685726, +), CAediting_213081(130687760, +), CAediting_213082(130687797, +), CAediting_213083(130687806, +), CAediting_213084(130687811, +), CAediting_213085(130687821, +), CAediting_213086(130687823, +), CAediting_213087(130687830, +), CAediting_213088(130687831, +), CAediting_213089(130687847, +), CAediting_213090(130687848, +), CAediting_213091(130687860, +), CAediting_213092(130687864, +), CAediting_213093(130687882, +), CAediting_213094(130687883, +), CAediting_213095(130687884, +), CAediting_213096(130687889, +), CAediting_213097(130687893, +), CAediting_213098(130687897, +), CAediting_213099(130687906, +), CAediting_213100(130687925, +), CAediting_213101(130687943, +), CAediting_213102(130687945, +), CAediting_213103(130687953, +), CAediting_213104(130687954, +), CAediting_213105(130687974, +), CAediting_213106(130687987, +), CAediting_213107(130687992, +), CAediting_213108(130687993, +),

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RNA editing positional annotations for CYP4F30P using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_213063	chr2_130685486_+	ncRNA_exonic
CAediting_213064	chr2_130685509_+	ncRNA_exonic
CAediting_213065	chr2_130685516_+	ncRNA_exonic
CAediting_213066	chr2_130685544_+	ncRNA_exonic
CAediting_213067	chr2_130685565_+	ncRNA_exonic
CAediting_213068	chr2_130685569_+	ncRNA_exonic
CAediting_213069	chr2_130685582_+	ncRNA_exonic
CAediting_213070	chr2_130685591_+	ncRNA_exonic
CAediting_213071	chr2_130685594_+	ncRNA_exonic
CAediting_213072	chr2_130685630_+	ncRNA_exonic
CAediting_213073	chr2_130685637_+	ncRNA_exonic
CAediting_213074	chr2_130685645_+	ncRNA_exonic
CAediting_213075	chr2_130685648_+	ncRNA_exonic
CAediting_213076	chr2_130685665_+	ncRNA_exonic
CAediting_213077	chr2_130685674_+	ncRNA_exonic
CAediting_213078	chr2_130685717_+	ncRNA_exonic
CAediting_213079	chr2_130685725_+	ncRNA_exonic
CAediting_213080	chr2_130685726_+	ncRNA_exonic
CAediting_213081	chr2_130687760_+	ncRNA_intronic
CAediting_213082	chr2_130687797_+	ncRNA_intronic
CAediting_213083	chr2_130687806_+	ncRNA_intronic
CAediting_213084	chr2_130687811_+	ncRNA_intronic
CAediting_213085	chr2_130687821_+	ncRNA_intronic
CAediting_213086	chr2_130687823_+	ncRNA_intronic
CAediting_213087	chr2_130687830_+	ncRNA_intronic
CAediting_213088	chr2_130687831_+	ncRNA_intronic
CAediting_213089	chr2_130687847_+	ncRNA_intronic
CAediting_213090	chr2_130687848_+	ncRNA_intronic
CAediting_213091	chr2_130687860_+	ncRNA_intronic
CAediting_213092	chr2_130687864_+	ncRNA_intronic
CAediting_213093	chr2_130687882_+	ncRNA_intronic
CAediting_213094	chr2_130687883_+	ncRNA_intronic
CAediting_213095	chr2_130687884_+	ncRNA_intronic
CAediting_213096	chr2_130687889_+	ncRNA_intronic
CAediting_213097	chr2_130687893_+	ncRNA_intronic
CAediting_213098	chr2_130687897_+	ncRNA_intronic
CAediting_213099	chr2_130687906_+	ncRNA_intronic
CAediting_213100	chr2_130687925_+	ncRNA_intronic
CAediting_213101	chr2_130687943_+	ncRNA_intronic
CAediting_213102	chr2_130687945_+	ncRNA_intronic
CAediting_213103	chr2_130687953_+	ncRNA_intronic
CAediting_213104	chr2_130687954_+	ncRNA_intronic
CAediting_213105	chr2_130687974_+	ncRNA_intronic
CAediting_213106	chr2_130687987_+	ncRNA_intronic
CAediting_213107	chr2_130687992_+	ncRNA_intronic
CAediting_213108	chr2_130687993_+	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_213063	chr2_130685486_+	SINE	Alu	AluSq2
CAediting_213064	chr2_130685509_+	SINE	Alu	AluSq2
CAediting_213065	chr2_130685516_+	SINE	Alu	AluSq2
CAediting_213066	chr2_130685544_+	SINE	Alu	AluSq2
CAediting_213067	chr2_130685565_+	SINE	Alu	AluSq2
CAediting_213068	chr2_130685569_+	SINE	Alu	AluSq2
CAediting_213069	chr2_130685582_+	SINE	Alu	AluSq2
CAediting_213070	chr2_130685591_+	SINE	Alu	AluSq2
CAediting_213071	chr2_130685594_+	SINE	Alu	AluSq2
CAediting_213072	chr2_130685630_+	SINE	Alu	AluSq2
CAediting_213073	chr2_130685637_+	SINE	Alu	AluSq2
CAediting_213074	chr2_130685645_+	SINE	Alu	AluSq2
CAediting_213075	chr2_130685648_+	SINE	Alu	AluSq2
CAediting_213076	chr2_130685665_+	SINE	Alu	AluSq2
CAediting_213077	chr2_130685674_+	SINE	Alu	AluSq2
CAediting_213078	chr2_130685717_+	SINE	Alu	AluSq2
CAediting_213079	chr2_130685725_+	SINE	Alu	AluSq2
CAediting_213080	chr2_130685726_+	SINE	Alu	AluSq2
CAediting_213081	chr2_130687760_+	SINE	Alu	AluSq2
CAediting_213082	chr2_130687797_+	SINE	Alu	AluSq2
CAediting_213083	chr2_130687806_+	SINE	Alu	AluSq2
CAediting_213084	chr2_130687811_+	SINE	Alu	AluSq2
CAediting_213085	chr2_130687821_+	SINE	Alu	AluSq2
CAediting_213086	chr2_130687823_+	SINE	Alu	AluSq2
CAediting_213087	chr2_130687830_+	SINE	Alu	AluSq2
CAediting_213088	chr2_130687831_+	SINE	Alu	AluSq2
CAediting_213089	chr2_130687847_+	SINE	Alu	AluSq2
CAediting_213090	chr2_130687848_+	SINE	Alu	AluSq2
CAediting_213091	chr2_130687860_+	SINE	Alu	AluSq2
CAediting_213092	chr2_130687864_+	SINE	Alu	AluSq2
CAediting_213093	chr2_130687882_+	SINE	Alu	AluSq2
CAediting_213094	chr2_130687883_+	SINE	Alu	AluSq2
CAediting_213095	chr2_130687884_+	SINE	Alu	AluSq2
CAediting_213096	chr2_130687889_+	SINE	Alu	AluSq2
CAediting_213097	chr2_130687893_+	SINE	Alu	AluSq2
CAediting_213098	chr2_130687897_+	SINE	Alu	AluSq2
CAediting_213099	chr2_130687906_+	SINE	Alu	AluSq2
CAediting_213100	chr2_130687925_+	SINE	Alu	AluSq2
CAediting_213101	chr2_130687943_+	SINE	Alu	AluSq2
CAediting_213102	chr2_130687945_+	SINE	Alu	AluSq2
CAediting_213103	chr2_130687953_+	SINE	Alu	AluSq2
CAediting_213104	chr2_130687954_+	SINE	Alu	AluSq2
CAediting_213105	chr2_130687974_+	SINE	Alu	AluSq2
CAediting_213106	chr2_130687987_+	SINE	Alu	AluSq2
CAediting_213107	chr2_130687992_+	SINE	Alu	AluSq2
CAediting_213108	chr2_130687993_+	SINE	Alu	AluSq2

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RNA A-to-I editing events in the alternative splicing sites for CYP4F30P

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000214081.6.CYP4F30P.

Correlation between RNA A-to-I editing and PSI for ENSG00000214081.6.CYP4F30P.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CYP4F30P

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for CYP4F30P

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for CYP4F30P

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_688080	chr9_63819626_+	ENSG00000214081.6	ENST00000450440.1	hsa-miR-4477b	130681473	130681479	7mer-m8	130681460	130681480	147	-10.72
CAediting_1399425	chr20_1392958_-	ENSG00000214081.6	ENST00000450440.1	hsa-miR-6869-5p	130681360	130681366	7mer-m8	130681347	130681367	148	-19.64
CAediting_396018	chr5_1062918_-	ENSG00000214081.6	ENST00000450440.1	hsa-miR-4635	130681474	130681480	7mer-m8	130681457	130681481	145	-22.03

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1054808	chr15_66496985_-	ENSG00000214081.6	ENST00000450440.1	hsa-miR-4512	130690281	130690287	7mer-m8	130690269	130690288	148	-17.18

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CYP4F30P

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000397485.5	processed_transcript
ENST00000438109.4	processed_transcript

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_213063	ENST00000397485.5	chr2_130685486_+	-781.30	-776.20	-795.40
CAediting_213064	ENST00000397485.5	chr2_130685509_+	-776.40	-776.20	-795.40
CAediting_213065	ENST00000397485.5	chr2_130685516_+	-777.00	-776.20	-795.40
CAediting_213066	ENST00000397485.5	chr2_130685544_+	-782.30	-776.20	-795.40
CAediting_213067	ENST00000397485.5	chr2_130685565_+	-775.50	-776.20	-795.40
CAediting_213068	ENST00000397485.5	chr2_130685569_+	-774.80	-776.20	-795.40
CAediting_213069	ENST00000397485.5	chr2_130685582_+	-778.30	-776.20	-795.40
CAediting_213070	ENST00000397485.5	chr2_130685591_+	-780.10	-776.20	-795.40
CAediting_213071	ENST00000397485.5	chr2_130685594_+	-775.90	-776.20	-795.40
CAediting_213072	ENST00000397485.5	chr2_130685630_+	-776.50	-776.20	-795.40
CAediting_213073	ENST00000397485.5	chr2_130685637_+	-775.80	-776.20	-795.40
CAediting_213074	ENST00000397485.5	chr2_130685645_+	-776.70	-776.20	-795.40
CAediting_213075	ENST00000397485.5	chr2_130685648_+	-777.10	-776.20	-795.40
CAediting_213076	ENST00000397485.5	chr2_130685665_+	-775.80	-776.20	-795.40
CAediting_213077	ENST00000397485.5	chr2_130685674_+	-776.20	-776.20	-795.40
CAediting_213078	ENST00000397485.5	chr2_130685717_+	-776.40	-776.20	-795.40
CAediting_213079	ENST00000397485.5	chr2_130685725_+	-776.20	-776.20	-795.40
CAediting_213080	ENST00000397485.5	chr2_130685726_+	-780.90	-776.20	-795.40
CAediting_213063	ENST00000438109.4	chr2_130685486_+	-798.20	-794.80	-812.10
CAediting_213064	ENST00000438109.4	chr2_130685509_+	-794.10	-794.80	-812.10
CAediting_213065	ENST00000438109.4	chr2_130685516_+	-797.00	-794.80	-812.10
CAediting_213066	ENST00000438109.4	chr2_130685544_+	-799.30	-794.80	-812.10
CAediting_213067	ENST00000438109.4	chr2_130685565_+	-794.10	-794.80	-812.10
CAediting_213068	ENST00000438109.4	chr2_130685569_+	-793.40	-794.80	-812.10
CAediting_213069	ENST00000438109.4	chr2_130685582_+	-796.90	-794.80	-812.10
CAediting_213070	ENST00000438109.4	chr2_130685591_+	-797.70	-794.80	-812.10
CAediting_213071	ENST00000438109.4	chr2_130685594_+	-795.00	-794.80	-812.10
CAediting_213072	ENST00000438109.4	chr2_130685630_+	-795.90	-794.80	-812.10
CAediting_213073	ENST00000438109.4	chr2_130685637_+	-795.20	-794.80	-812.10
CAediting_213074	ENST00000438109.4	chr2_130685645_+	-794.80	-794.80	-812.10
CAediting_213075	ENST00000438109.4	chr2_130685648_+	-794.80	-794.80	-812.10
CAediting_213076	ENST00000438109.4	chr2_130685665_+	-793.30	-794.80	-812.10
CAediting_213077	ENST00000438109.4	chr2_130685674_+	-795.60	-794.80	-812.10
CAediting_213078	ENST00000438109.4	chr2_130685717_+	-795.50	-794.80	-812.10
CAediting_213079	ENST00000438109.4	chr2_130685725_+	-794.80	-794.80	-812.10
CAediting_213080	ENST00000438109.4	chr2_130685726_+	-799.50	-794.80	-812.10

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Relation with ADAR for CYP4F30P

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for CYP4F30P

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for CYP4F30P

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for CYP4F30P

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for CYP4F30P

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene