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lncRNA: ENSG00000281332

Summary for LINC00997

Gene summary

Gene information	Ensembl ID	ENSG00000281332
	Gene symbol	LINC00997
	Gene name	long intergenic non-protein coding RNA 997
	HGNC	48952
	Entrez ID
	Gene type	lincRNA
	Synonyms	LINC00997\|07p14.3
	UniProtAcc

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Structure and expression level for LINC00997

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000281332	3.973090e+02	1.232131e+00	1.467099e-01	8.398420e+00	4.530000e-17	8.000000e-16	UP	KIRP

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000281332	3.912120e-01	7.876653e-03	CHOL	9.558824e-03
ENSG00000281332	3.369256e-01	1.322636e-17	KIRC	7.534003e-17
ENSG00000281332	3.489498e-01	6.759289e-13	LIHC	4.311960e-12

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lncRNA-Protein interaction for LINC00997

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000281332	ENST00000628855	LINC00997	ENSG00000166987	MBD6	41.32	94.5191	Q96DN6	TF,Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000281332	ENST00000628855	LINC00997	ENSG00000177045	SIX5	54.48	94.2331	Q8N196	TF	NA
ENSG00000281332	ENST00000628855	LINC00997	ENSG00000166987	MBD6	41.32	94.5891	Q96DN6	TF,Epi	NA
ENSG00000281332	ENST00000628855	LINC00997	ENSG00000136451	VEZF1	33.68	91.5238	Q14119	TF	NA
ENSG00000281332	ENST00000628855	LINC00997	ENSG00000065029	ZNF76	21.55	91.9262	P36508	TF	NA
ENSG00000281332	ENST00000628855	LINC00997	ENSG00000146676	PURB	13.53	91.3355	Q96QR8	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000281332	ENST00000628855	LINC00997	ENSG00000149532	CPSF7	20.32	94.5215	Q8N684	RBP	PAR-CLIP
ENSG00000281332	ENST00000628855	LINC00997	ENSG00000077312	SNRPA	15.7	91.455	P09012	RBP	NA

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lncRNA-DNA interaction for LINC00997

lncRNA targets the enhancer region and positively regulates the gene expression.

Only predicted by TDF

CNOT4,TIGD5,PUS7,E2F6,CHTOP,TGIF1,MECP2,PHF1,RBM6,ILF3,RBM39,LSM11,NOL3,ZFHX3,HSF4,RBM41,NOL9,PUM2,RBM5,RC3H1,ELF2,RBMS1,NFYB,ZFP62,DDX54,ZNF44,MZF1,MEX3D,PTBP3,SGSM2,NRF1,SMAD3,ZNF91,SRSF4,WIZ,IRX3,SF3B4,ZNF84,AGO2,CELF1,RBM4B,SCMH1,DDX42,DMTF1,CSTF3,VEZF1,TIGD1,RBM10,RBM27,DDX51,TRA2A,PURB,AGO3,PCBP4,KMT2A,PUS7L,MYRF,CENPB,DHX34,RBM28,SRSF2,RARA,MBD6,FIZ1,NR2C1,TFCP2,CPSF7,MBD2,ZNF83,SFPQ,THOC2,RNPC3,ZNF3,ZFP69,SNRPA,ZNF34,NXF1,SAFB2,ZNF8,RBM33,NR2C2,PCGF2,ATF2,SIX5,ZNF10

Exist in public source

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for LINC00997

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

ORF mutation

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000281332	ENST00000628855	exon_skip_111863	chr14:23565815-23565892	-15.68	-0.2148	AP1G2	ENST00000308724,ENST00000397120	Frame-shift
ENSG00000281332	ENST00000628855	exon_skip_382458	chr3:38131595-38131638	-8.12	-0.2082	ACAA1	ENST00000333167	Frame-shift

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for LINC00997

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000281332.1	ENST00000628855.1	87	206	469

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential