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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000280693

Summary for SH3PXD2A-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000280693

Gene symbol

SH3PXD2A-AS1

Gene nameSH3PXD2A antisense RNA 1
HGNC

45242

Entrez ID

100505839

Gene typeantisense
Synonyms10q24.33|SH3PXD2A-AS1
UniProtAcc

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Structure and expression level for SH3PXD2A-AS1

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002806932.732878e+023.781012e+001.075248e+003.516409e+004.374260e-044.065557e-03UPCESC
ENSG000002806932.351546e+023.802990e+002.669856e-011.424417e+014.870000e-461.020000e-44UPLUSC
ENSG000002806931.562976e+022.927328e+002.348348e-011.246548e+011.150000e-354.380000e-34UPCOAD
ENSG000002806931.667442e+022.604792e+004.297075e-016.061779e+001.350000e-093.350000e-08UPREAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value

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lncRNA-Protein interaction for SH3PXD2A-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for SH3PXD2A-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
EVPL,GIPC1,CRYBG2,GPR153,MEAK7,SERPINB1,PLIN3,TRIM7,S100A16,RAB10,TGM1,STN1,PPL,LYPD3,PERP,C1orf116,HK1,DOCK9,AHNAK2,GJB5,NIBAN2,PLEKHN1,CELSR1,RARG,C6orf132,LAD1,LRRC8A,BICDL2,TMEM79,ANXA2,TRIM29
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for SH3PXD2A-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000280693ENST00000625265exon_skip_368285chr22:29329711-29329720-2.79-1.3950AP1B1ENST00000357586,ENST00000405198In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for SH3PXD2A-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation
ENSG00000280693ENSG00000092295TGM1BLCA,CESC,ESCA,HNSC,STADCESC
ENSG00000280693ENSG00000112378PERPBLCA,CESC,ESCA,PAAD,READ,STADCESC,READ
ENSG00000280693ENSG00000136830NIBAN2BLCA,CESC,ESCA,HNSC,PAAD,STADCESC
ENSG00000280693ENSG00000137699TRIM29BLCA,CESC,ESCA,HNSC,PAAD,READ,STADCESC,READ
ENSG00000280693ENSG00000188112C6orf132BLCA,CESC,HNSC,PAAD,STADCESC
ENSG00000280693ENSG00000189280GJB5BLCA,CESC,ESCA,PAAD,READ,STADCESC,READ
ENSG00000280693ENSG00000084733RAB10CESC,ESCA,HNSC,STAD,UVMCESC
ENSG00000280693ENSG00000118898PPLCESC,ESCA,HNSC,PAAD,STADCESC
ENSG00000280693ENSG00000123159GIPC1CESC,ESCA,HNSC,PAAD,STADCESC
ENSG00000280693ENSG00000159166LAD1CESC,ESCA,HNSC,PAAD,STADCESC
ENSG00000280693ENSG00000163472TMEM79CESC,ESCA,HNSC,PAAD,STADCESC
ENSG00000280693ENSG00000167880EVPLCESC,ESCA,HNSC,PAAD,STADCESC
ENSG00000280693ENSG00000176092CRYBG2CESC,ESCA,HNSC,PAAD,STADCESC
ENSG00000280693ENSG00000187583PLEKHN1CESC,ESCA,HNSC,PAAD,STADCESC

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000280693.1ENST00000627886.1809641206
ENSG00000280693.1ENST00000625265.112245082