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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000278948

Summary for RP5-1039K5.12

check button Gene summary

Gene informationEnsembl ID

ENSG00000278948

Gene symbol

RP5-1039K5.12

Gene name
HGNC
Entrez ID
Gene typeTEC
Synonyms
UniProtAcc

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Structure and expression level for RP5-1039K5.12

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002789481.812412e+021.301416e+001.413069e-019.209858e+003.270000e-205.420000e-19UPKICH
ENSG000002789482.245296e+02-1.016644e+002.158107e-01-4.710815e+002.470000e-061.990000e-05DOWNBLCA
ENSG000002789482.644525e+02-2.032209e+003.899097e-01-5.212000e+001.870000e-076.820000e-06DOWNESCA
ENSG000002789481.476229e+02-1.131064e+009.086033e-02-1.244838e+011.430000e-352.130000e-33DOWNPRAD
ENSG000002789481.317020e+02-1.010913e+009.828144e-02-1.028590e+018.160000e-256.600000e-24DOWNBRCA

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG00000278948-3.543618e-016.990599e-06ESCA6.992850e-04
ENSG000002789484.817371e-011.756736e-06KICH4.688506e-06
ENSG00000278948-3.868948e-014.067224e-21PRAD1.174710e-19

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lncRNA-Protein interaction for RP5-1039K5.12

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000278948ENST00000624344RP5-1039K5.12ENSG00000124177CHD646.9593.0175Q8TD26EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for RP5-1039K5.12

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP5-1039K5.12

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
PYM1,NDUFC1,MICU1,MRPL44,PTGES3,KLHDC9,COQ5,DNAJC7,PLS1,NECAP2,ANG,SLC50A1,MCCC2,UTP18,PDZD11,SDHB,MACROH2A1,ETFA,LAMTOR5,MRPL58,GLRX2,PNKD,OSTC,ACP1,MPV17,PPIB,DECR1,COX5A,PSMA4,PSME1,TMCO1,DDX39A,DDX41,DOK1,PSMB8,TLCD1,GLA,MAIP1,SUMO2,MRPS15,EEF1E1,TPM3,PRR13,ARRB2,GON7,COX6A1,PPIA,CALM2,RAN,SDCBP,RPA3,PTRH2,SSBP1,GPI,UBB,RABGGTB,UQCRH,PARK7,PTMA,SNRPC,AUP1,TRAF4,CIAO2A,SRP14,PPA1
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000278948ENST00000624344exon_skip_75223chr11:72012400-72012442-9.03-0.6946NUMA1ENST00000393695In-frame
ENSG00000278948ENST00000624344exon_skip_104174chr13:79353152-79353224-10.34-0.1723RBM26ENST00000438737In-frame
ENSG00000278948ENST00000624344exon_skip_335378chr2:237751199-237751271-9.40-0.1621LRRFIP1ENST00000392000In-frame
ENSG00000278948ENST00000624344exon_skip_507736chr9:129915965-129915980-5.39-0.5989FNBP1ENST00000446176In-frame
ENSG00000278948ENST00000624344exon_skip_382356chr3:37091466-37091538-12.14-0.2428LRRFIP2ENST00000336686In-frame
ENSG00000278948ENST00000624344exon_skip_444897chr5:141588223-141588250-9.55-1.9100DIAPH1ENST00000389054In-frame
ENSG00000278948ENST00000624344exon_skip_48296chr10:26755654-26755741-14.15-0.1747ABI1ENST00000376142In-frame
ENSG00000278948ENST00000624344exon_skip_114227chr14:73316389-73316422-11.26-0.4021NUMBENST00000355058,ENST00000555238In-frame
ENSG00000278948ENST00000624344exon_skip_96112chr12:109945259-109945349-22.07-0.5016GIT2ENST00000355312In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000278948ENST00000624344exon_skip_153096chr17:44074968-44075087-17.54-0.1499G6PC3ENST00000269097Frame-shift

check buttonlncRNA targets by miRNA.
lncRNA targets by miRNA
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source
ENSG00000278948hsa-mir-425ENST00000624344chr22:37944522-37944618189.00-81.5595NA
ENSG00000278948hsa-mir-425ENST00000624344chr22:37944753-37944838167.00-81.4381NA
ENSG00000278948hsa-mir-425ENST00000624344chr22:37943287-37943371166.00-73.5581NA
ENSG00000278948hsa-mir-425ENST00000624344chr22:37943714-37943798160.00-64.1285NA
ENSG00000278948hsa-mir-425ENST00000624344chr22:37944284-37944373155.00-67.3089NA
ENSG00000278948hsa-mir-425ENST00000624344chr22:37943058-37943153154.00-79.3092NA
ENSG00000278948hsa-mir-425ENST00000624344chr22:37944170-37944249154.00-62.0683NA
ENSG00000278948hsa-mir-425ENST00000624344chr22:37943870-37943953152.00-73.1884NA
ENSG00000278948hsa-mir-425ENST00000624344chr22:37943450-37943544149.00-71.3991NA
ENSG00000278948hsa-mir-425ENST00000624344chr22:37943962-37944056149.00-86.1792NA
ENSG00000278948hsa-mir-425ENST00000624344chr22:37944071-37944148148.00-77.2382NA
ENSG00000278948hsa-mir-425ENST00000624344chr22:37944374-37944464146.00-72.6090NA
ENSG00000278948hsa-mir-425ENST00000624344chr22:37943578-37943669142.00-77.2490NA
ENSG00000278948hsa-mir-199bENST00000624344chr22:37943837-37943962223.00-99.72114NA
ENSG00000278948hsa-mir-199bENST00000624344chr22:37944090-37944211215.00-112.14115NA
ENSG00000278948hsa-mir-199bENST00000624344chr22:37943138-37943239192.00-89.15100NA
ENSG00000278948hsa-mir-199bENST00000624344chr22:37943605-37943709192.00-85.35115NA
ENSG00000278948hsa-mir-199bENST00000624344chr22:37944375-37944502184.00-104.04124NA
ENSG00000278948hsa-mir-199bENST00000624344chr22:37943981-37944103173.00-113.77123NA
ENSG00000278948hsa-mir-199bENST00000624344chr22:37944489-37944603173.00-106.88109NA
ENSG00000278948hsa-mir-199bENST00000624344chr22:37943741-37943854172.00-82.63110NA
ENSG00000278948hsa-mir-199bENST00000624344chr22:37943255-37943359170.00-97.07104NA
ENSG00000278948hsa-mir-199bENST00000624344chr22:37943423-37943548170.00-92.49119NA
ENSG00000278948hsa-mir-199bENST00000624344chr22:37944682-37944788163.00-103.68111NA
ENSG00000278948hsa-mir-199bENST00000624344chr22:37943051-37943146158.00-91.62101NA
ENSG00000278948hsa-mir-199bENST00000624344chr22:37944221-37944333150.00-97.00115NA
ENSG00000278948hsa-mir-146bENST00000624344chr22:37943982-37944056186.00-75.5274NA
ENSG00000278948hsa-mir-146bENST00000624344chr22:37943196-37943257180.00-70.2170NA
ENSG00000278948hsa-mir-146bENST00000624344chr22:37943051-37943116173.00-63.4565NA
ENSG00000278948hsa-mir-146bENST00000624344chr22:37943328-37943408172.00-65.7479NA
ENSG00000278948hsa-mir-146bENST00000624344chr22:37944113-37944190171.00-69.6475NA
ENSG00000278948hsa-mir-146bENST00000624344chr22:37943859-37943935166.00-60.7869NA
ENSG00000278948hsa-mir-146bENST00000624344chr22:37943400-37943470164.00-57.6874NA
ENSG00000278948hsa-mir-146bENST00000624344chr22:37943550-37943628162.00-68.7475NA
ENSG00000278948hsa-mir-146bENST00000624344chr22:37944253-37944320162.00-63.9072NA
ENSG00000278948hsa-mir-146bENST00000624344chr22:37944783-37944853149.00-69.5775NA
ENSG00000278948hsa-mir-146bENST00000624344chr22:37944630-37944701144.00-68.0172NA
ENSG00000278948hsa-mir-146bENST00000624344chr22:37944053-37944121141.00-75.3272NA
ENSG00000278948hsa-mir-766ENST00000624344chr22:37943996-37944107237.00-117.77116NA
ENSG00000278948hsa-mir-766ENST00000624344chr22:37944774-37944892225.00-108.04115NA
ENSG00000278948hsa-mir-766ENST00000624344chr22:37943178-37943288207.00-105.96110NA
ENSG00000278948hsa-mir-766ENST00000624344chr22:37943512-37943614203.00-91.12102NA
ENSG00000278948hsa-mir-766ENST00000624344chr22:37944557-37944669190.00-100.33100NA
ENSG00000278948hsa-mir-766ENST00000624344chr22:37944414-37944533189.00-103.65115NA
ENSG00000278948hsa-mir-766ENST00000624344chr22:37943876-37943990188.00-104.73110NA
ENSG00000278948hsa-mir-766ENST00000624344chr22:37944122-37944249173.00-104.39114NA
ENSG00000278948hsa-mir-766ENST00000624344chr22:37943666-37943777162.00-76.06110NA
ENSG00000278948hsa-mir-766ENST00000624344chr22:37943311-37943422161.00-95.50112NA
ENSG00000278948hsa-mir-766ENST00000624344chr22:37943071-37943188155.00-92.62116NA
ENSG00000278948hsa-mir-766ENST00000624344chr22:37944657-37944777152.00-103.41118NA
ENSG00000278948hsa-mir-766ENST00000624344chr22:37944269-37944379150.00-101.96114NA

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Variants for RP5-1039K5.12

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000278948ENST00000624344MACROH2A1ENSG00000113648ENST00000423969-0.1628266BRCA-
ENSG00000278948ENST00000624344MACROH2A1ENSG00000113648ENST00000510038-0.6621145BRCA-
ENSG00000278948ENST00000624344MCCC2ENSG00000131844ENST00000509358-0.3086668PRAD-
ENSG00000278948ENST00000624344SLC50A1ENSG00000169241ENST00000484157-0.21891733BLCA,BRCA-
ENSG00000278948ENST00000624344PLS1ENSG00000120756ENST00000497002-0.2948995-KICH
ENSG00000278948ENST00000624344EEF1E1ENSG00000124802ENST00000429723-0.1344129-KICH
ENSG00000278948ENST00000624344EEF1E1ENSG00000124802ENST00000502429-0.13221624-KICH
ENSG00000278948ENST00000624344KLHDC9ENSG00000162755ENST00000368011-0.112674BRCAKICH
ENSG00000278948ENST00000624344ANGENSG00000214274ENST00000336811-0.15591635-KICH
ENSG00000278948ENST00000624344ANGENSG00000214274ENST00000397990-0.15591635-KICH
ENSG00000278948ENST00000624344RPA3ENSG00000106399ENST00000406109-0.1307556ESCA-
ENSG00000278948ENST00000624344RPA3ENSG00000106399ENST00000396682-0.2124910ESCA-
ENSG00000278948ENST00000624344RPA3ENSG00000106399ENST00000401447-0.3267737ESCA-
ENSG00000278948ENST00000624344DDX39AENSG00000123136ENST00000242776-0.2485893BLCA,ESCA,BRCA-
ENSG00000278948ENST00000624344TLCD1ENSG00000160606ENST00000292090-0.1321921BLCA,PRAD,BRCA-
ENSG00000278948ENST00000624344TLCD1ENSG00000160606ENST00000394933-0.26461309BLCA,PRAD,BRCA-

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types
ENSG00000278948RP5-1039K5.12,hsa-mir-766,C22orf23LGG,UVM,GBM,SARC,THYM
ENSG00000278948RP5-1039K5.12,hsa-mir-425,TNS1UCEC,TGCT,PRAD,UVM,THYM
ENSG00000278948RP5-1039K5.12,hsa-mir-425,ZCCHC24UCEC,TGCT,PRAD,UVM,THYM
ENSG00000278948RP5-1039K5.12,hsa-mir-425,SSPNUCEC,TGCT,PRAD,UVM,THYM
ENSG00000278948RP5-1039K5.12,hsa-mir-146b,PDGFDTGCT,THCA,PRAD,UVM,DLBC

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000278948.1ENST00000624344.1222105459877