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lncRNA: ENSG00000277283

Summary for RP1-267D11.6

Gene summary

Gene information	Ensembl ID	ENSG00000277283
	Gene symbol	RP1-267D11.6
	Gene name
	HGNC
	Entrez ID
	Gene type	antisense
	Synonyms
	UniProtAcc

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Structure and expression level for RP1-267D11.6

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000277283	1.058827e+02	2.040352e+00	2.657446e-01	7.677869e+00	1.620000e-14	3.750000e-13	UP	CHOL

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000277283	5.583115e-01	6.739283e-05	CHOL	2.313362e-04

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lncRNA-Protein interaction for RP1-267D11.6

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000277283	ENST00000611079	RP1-267D11.6	ENSG00000111707	SUDS3	16.71	90.5447	Q9H7L9	Epi	NA
ENSG00000277283	ENST00000611079	RP1-267D11.6	ENSG00000176396	EID2	13.91	92.8403	Q8N6I1	Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000277283	ENST00000611079	RP1-267D11.6	ENSG00000204231	RXRB	43.76	92.583	P28702	TF	NA
ENSG00000277283	ENST00000611079	RP1-267D11.6	ENSG00000256223	ZNF10	28.19	94.1874	P21506	TF	NA
ENSG00000277283	ENST00000611079	RP1-267D11.6	ENSG00000102878	HSF4	21.71	91.1559	Q9ULV5	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000277283	ENST00000611079	RP1-267D11.6	ENSG00000185163	DDX51	33.15	91.1781	Q8N8A6	RBP	NA
ENSG00000277283	ENST00000611079	RP1-267D11.6	ENSG00000131051	RBM39	25.98	90.326	Q14498	RBP	NA

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lncRNA-DNA interaction for RP1-267D11.6

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP1-267D11.6

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

FNDC3B,MAP4,TCN2,SLC39A14,PYGL

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

ORF mutation

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000277283	ENST00000611079	exon_skip_153767	chr17:48057031-48057121	-17.74	-0.3168	NFE2L1	ENST00000362042	In-frame
ENSG00000277283	ENST00000611079	exon_skip_319223	chr19:43526200-43526349	-29.69	-0.2232	ETHE1	ENST00000292147	Frame-shift
ENSG00000277283	ENST00000611079	exon_skip_382458	chr3:38131595-38131638	-10.57	-0.3775	ACAA1	ENST00000333167	Frame-shift
ENSG00000277283	ENST00000611079	exon_skip_41841	chr10:68756272-68756483	-25.91	-0.1682	CCAR1	ENST00000265872	Frame-shift
ENSG00000277283	ENST00000611079	exon_skip_114365	chr14:74290026-74290118	-16.56	-0.1926	ABCD4	ENST00000356924	Frame-shift
ENSG00000277283	ENST00000611079	exon_skip_287763	chr17:28884224-28884315	-19.89	-0.2426	FLOT2	ENST00000394908	Frame-shift
ENSG00000277283	ENST00000611079	exon_skip_370518	chr22:50247691-50247776	-16.25	-0.2057	HDAC10	ENST00000216271	Frame-shift
ENSG00000277283	ENST00000611079	exon_skip_374375	chr3:49675182-49675309	-19.48	-0.1651	APEH	ENST00000296456	Frame-shift
ENSG00000277283	ENST00000611079	exon_skip_374581	chr3:50110378-50110463	-13.91	-0.1761	RBM5	ENST00000347869	Frame-shift
ENSG00000277283	ENST00000611079	exon_skip_380242	chr3:186784961-186785101	-15.57	-0.1390	EIF4A2	ENST00000323963	Frame-shift
ENSG00000277283	ENST00000611079	exon_skip_348254	chr2:241680228-241680319	-18.51	-0.2373	DTYMK	ENST00000305784	Frame-shift
ENSG00000277283	ENST00000611079	exon_skip_52701	chr10:97468965-97469104	-22.83	-0.2003	MMS19	ENST00000370782,ENST00000438925	Frame-shift

lncRNA targets by miRNA.

LncRNA Ensembl ID	miRNA ID	LncRNA ENST ID	Binding site in lncRNA	Score	Energy	Align Len	Public source
ENSG00000277283	hsa-mir-378a	ENST00000611079	chr12:120117373-120117441	190.00	-81.63	59	NA
ENSG00000277283	hsa-mir-378a	ENST00000611079	chr12:120117297-120117367	178.00	-82.14	59	NA
ENSG00000277283	hsa-mir-378a	ENST00000611079	chr12:120116957-120117029	172.00	-79.51	68	NA
ENSG00000277283	hsa-mir-378a	ENST00000611079	chr12:120116908-120116946	160.00	-63.45	34	NA
ENSG00000277283	hsa-mir-378a	ENST00000611079	chr12:120117101-120117170	155.00	-80.47	70	NA
ENSG00000277283	hsa-mir-378a	ENST00000611079	chr12:120117544-120117611	155.00	-59.25	61	NA
ENSG00000277283	hsa-mir-378a	ENST00000611079	chr12:120117467-120117535	153.00	-77.66	63	NA
ENSG00000277283	hsa-mir-378a	ENST00000611079	chr12:120118292-120118359	147.00	-54.60	58	NA
ENSG00000277283	hsa-mir-378a	ENST00000611079	chr12:120118835-120118898	146.00	-57.77	59	NA
ENSG00000277283	hsa-mir-378a	ENST00000611079	chr12:120117847-120117917	145.00	-66.85	68	NA
ENSG00000277283	hsa-mir-378a	ENST00000611079	chr12:120118711-120118774	143.00	-58.90	65	NA
ENSG00000277283	hsa-mir-378a	ENST00000611079	chr12:120118371-120118449	142.00	-63.61	73	NA
ENSG00000277283	hsa-mir-378a	ENST00000611079	chr12:120118505-120118573	142.00	-70.41	63	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120118638-120118718	223.00	-71.39	77	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120117370-120117451	194.00	-85.95	73	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120117252-120117331	181.00	-92.69	78	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120116922-120116999	175.00	-82.69	79	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120118908-120118991	173.00	-60.51	82	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120118162-120118251	164.00	-58.26	86	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120117611-120117690	160.00	-60.07	79	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120118842-120118915	156.00	-56.99	79	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120117511-120117589	149.00	-69.21	71	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120117686-120117761	146.00	-62.09	72	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120118440-120118519	146.00	-68.58	77	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120118342-120118430	144.00	-69.50	84	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120117783-120117862	143.00	-54.17	75	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120117894-120117985	143.00	-82.29	89	NA
ENSG00000277283	hsa-mir-378c	ENST00000611079	chr12:120118574-120118644	141.00	-73.30	79	NA

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Variants for RP1-267D11.6

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID	LncRNA ENST ID	PC Gene Name	PC Gene ID	PC ENST ID	dG	nDG	Cancer with PC gene up-regulation	Cancer with PC gene Down-regulation
ENSG00000277283	ENST00000611079	PYGL	ENSG00000100504	ENST00000532462	-0.1171	204	-	CHOL
ENSG00000277283	ENST00000611079	SLC39A14	ENSG00000104635	ENST00000240095	-0.1404	488	-	CHOL

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID	lncRNA-miRNA-mRNA	Cancer Types
ENSG00000277283	RP1-267D11.6,hsa-mir-378a,ISYNA1	KICH,TGCT,CHOL,PAAD,KIRP
ENSG00000277283	RP1-267D11.6,hsa-mir-378a,DTX3	KICH,TGCT,CHOL,PAAD,KIRP
ENSG00000277283	RP1-267D11.6,hsa-mir-378a,CRTC1	KICH,TGCT,CHOL,PAAD,KIRP

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000277283.1	ENST00000611079.1	90	270	1

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential