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lncRNA: ENSG00000275180

Summary for RP11-631N16.4

Gene summary

Gene information	Ensembl ID	ENSG00000275180
	Gene symbol	RP11-631N16.4
	Gene name
	HGNC
	Entrez ID
	Gene type	lincRNA
	Synonyms
	UniProtAcc

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Structure and expression level for RP11-631N16.4

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000275180	5.185305e+01	1.502815e+00	4.508152e-01	3.333550e+00	8.574520e-04	3.293129e-03	UP	GBM
ENSG00000275180	6.136851e+01	2.048835e+00	3.726252e-01	5.498378e+00	3.830000e-08	3.270000e-07	UP	CHOL
ENSG00000275180	6.522486e+01	1.672448e+00	1.711633e-01	9.771067e+00	1.500000e-22	1.040000e-21	UP	KIRC
ENSG00000275180	4.811323e+01	1.046554e+00	2.305634e-01	4.539116e+00	5.650000e-06	4.180000e-05	UP	BLCA
ENSG00000275180	2.529719e+01	1.983132e+00	2.368522e-01	8.372870e+00	5.620000e-17	8.780000e-16	UP	HNSC
ENSG00000275180	7.318674e+01	1.208416e+00	2.492372e-01	4.848456e+00	1.240000e-06	5.340000e-06	UP	KIRP
ENSG00000275180	3.472833e+01	1.497002e+00	1.674447e-01	8.940275e+00	3.880000e-19	8.850000e-18	UP	PRAD
ENSG00000275180	4.357661e+01	1.336155e+00	1.671158e-01	7.995385e+00	1.290000e-15	6.550000e-15	UP	LUSC
ENSG00000275180	4.923333e+01	1.746996e+00	1.749433e-01	9.986067e+00	1.750000e-23	2.280000e-22	UP	LUAD
ENSG00000275180	2.091558e+01	1.173599e+00	1.835192e-01	6.394966e+00	1.610000e-10	9.420000e-10	UP	COAD
ENSG00000275180	5.464205e+01	1.148706e+00	1.871353e-01	6.138373e+00	8.340000e-10	1.000000e-08	UP	STAD
ENSG00000275180	1.874030e+01	1.568090e+00	3.129863e-01	5.010092e+00	5.440000e-07	7.350000e-06	UP	READ

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000275180	4.767659e-01	9.294542e-04	CHOL	1.608377e-03
ENSG00000275180	3.051642e-01	1.252480e-04	ESCA	2.661521e-03
ENSG00000275180	3.215797e-01	1.010736e-14	PRAD	7.140598e-14

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lncRNA-Protein interaction for RP11-631N16.4

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

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lncRNA-DNA interaction for RP11-631N16.4

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-631N16.4

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000275180	ENST00000619323	exon_skip_1234	chr1:11658532-11658628	-9.39	-0.1010	FBXO44	ENST00000251547,ENST00000376770	In-frame
ENSG00000275180	ENST00000619323	exon_skip_470077	chr7:102397619-102397698	-9.64	-0.1819	PRKRIP1	ENST00000397912,ENST00000496391	Frame-shift

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000275180	ENST00000619323	exon_skip_66482	chr11:126274926-126275021	-11.16	-0.1744	FOXRED1	ENST00000263578	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_111863	chr14:23565815-23565892	-9.62	-0.1850	AP1G2	ENST00000308724,ENST00000397120	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_290158	chr17:42953723-42953778	-9.06	-0.3124	AARSD1	ENST00000427569	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_377198	chr3:123130479-123130616	-12.21	-0.1233	PDIA5	ENST00000316218	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_382458	chr3:38131595-38131638	-7.95	-0.2208	ACAA1	ENST00000333167	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_436035	chr5:79656957-79657001	-9.31	-0.2271	TENT2	ENST00000296783,ENST00000428308,ENST00000453514	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_470226	chr7:103307595-103307708	-7.86	-0.1123	PMPCB	ENST00000249269	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_133217	chr16:8635038-8635079	-8.31	-0.3957	METTL22	ENST00000381920	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_309204	chr19:49181348-49181461	-12.39	-0.1377	TRPM4	ENST00000252826	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_370518	chr22:50247691-50247776	-9.89	-0.1221	HDAC10	ENST00000216271	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_9446	chr1:147270931-147271005	-9.51	-0.3068	CHD1L	ENST00000369258	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_11029	chr1:154989559-154989707	-15.38	-0.1230	FLAD1	ENST00000292180	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_52701	chr10:97468965-97469104	-12.03	-0.1203	MMS19	ENST00000370782,ENST00000438925	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_53559	chr10:101793912-101793998	-9.11	-0.1183	OGA	ENST00000361464	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_58412	chr11:43892040-43892129	-7.41	-0.2744	ALKBH3	ENST00000302708	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_62623	chr11:69079833-69079883	-10.02	-0.2386	TPCN2	ENST00000294309	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_74009	chr11:64773429-64773505	-9.49	-0.1356	SF1	ENST00000377390	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_87733	chr12:120571190-120571291	-9.63	-0.1965	RNF10	ENST00000325954	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_92074	chr12:50142052-50142110	-5.75	-0.3194	CERS5	ENST00000317551	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_111870	chr14:23566561-23566686	-12.64	-0.1129	AP1G2	ENST00000397120	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_114365	chr14:74290026-74290118	-11.10	-0.1337	ABCD4	ENST00000356924	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_139933	chr16:90035632-90035687	-9.48	-0.1896	GAS8	ENST00000268699	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_292904	chr17:69251746-69251866	-15.23	-0.1771	ABCA5	ENST00000392676,ENST00000588877	In-frame
ENSG00000275180	ENST00000619323	exon_skip_302168	chr19:10680345-10680443	-9.85	-0.1107	ILF3	ENST00000590261	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_313557	chr19:5786748-5786845	-10.42	-0.1133	DUS3L	ENST00000309061	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_353131	chr20:58669290-58669453	-16.08	-0.1209	STX16	ENST00000371141	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_358821	chr20:63943652-63943669	-5.92	-0.4554	UCKL1	ENST00000354216	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_365497	chr22:38067703-38067770	-8.27	-0.1292	PICK1	ENST00000356976,ENST00000404072	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_374497	chr3:49999439-49999513	-7.95	-0.2038	RBM6	ENST00000266022	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_438188	chr5:141638954-141639021	-10.79	-0.1740	RELL2	ENST00000297164,ENST00000444782	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_442657	chr5:74730259-74730398	-12.06	-0.1117	GFM2	ENST00000296805,ENST00000509430	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_444499	chr5:138164086-138164133	-5.47	-0.3419	BRD8	ENST00000254900	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_446758	chr5:178212972-178213103	-13.19	-0.3769	PHYKPL	ENST00000308158	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_462160	chr6:127316449-127316502	-5.93	-0.1262	ECHDC1	ENST00000531967	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_466137	chr7:48103296-48103411	-11.67	-0.1216	UPP1	ENST00000331803,ENST00000395564	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_374581	chr3:50110378-50110463	-8.91	-0.2475	RBM5	ENST00000347869	Frame-shift
ENSG00000275180	ENST00000619323	exon_skip_5818	chr1:45568484-45568684	-13.75	-0.1026	AKR1A1	ENST00000351829,ENST00000372070	Frame-shift

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for RP11-631N16.4

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000275180.1	ENST00000619323.1	184	2877	2323

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential