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lncRNA: ENSG00000273226

Summary for RP11-513M16.8

Gene summary

Gene information	Ensembl ID	ENSG00000273226
	Gene symbol	RP11-513M16.8
	Gene name
	HGNC
	Entrez ID
	Gene type	antisense
	Synonyms
	UniProtAcc

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Structure and expression level for RP11-513M16.8

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000273226	3.257173e+01	-1.532504e+00	1.298573e-01	-1.180145e+01	3.840000e-32	1.430000e-30	DOWN	UCEC
ENSG00000273226	7.535916e+01	-1.080923e+00	2.411691e-01	-4.482013e+00	7.390000e-06	1.497200e-04	DOWN	ESCA
ENSG00000273226	4.226812e+01	-1.630573e+00	1.165241e-01	-1.399344e+01	1.710000e-44	3.370000e-43	DOWN	LUSC

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000273226	5.046849e-01	4.072767e-04	CHOL	8.457277e-04
ENSG00000273226	-3.169491e-01	3.851255e-15	LUAD	5.391757e-14
ENSG00000273226	-3.855098e-01	3.086271e-22	UCEC	3.909277e-20

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lncRNA-Protein interaction for RP11-513M16.8

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000273226	ENST00000609982	RP11-513M16.8	ENSG00000118058	KMT2A	76.65	95.7921	Q03164	TF,Epi	NA
ENSG00000273226	ENST00000609982	RP11-513M16.8	ENSG00000085224	ATRX	72.46	95.2071	P46100	Epi	NA
ENSG00000273226	ENST00000609982	RP11-513M16.8	ENSG00000185658	BRWD1	72.45	94.0077	Q9NSI6	Epi	NA
ENSG00000273226	ENST00000609982	RP11-513M16.8	ENSG00000124177	CHD6	69.08	92.6369	Q8TD26	Epi	NA
ENSG00000273226	ENST00000609982	RP11-513M16.8	ENSG00000032219	ARID4A	85.69	91.8627	P29374	Epi	NA
ENSG00000273226	ENST00000609982	RP11-513M16.8	ENSG00000055609	KMT2C	64.42	94.7061	Q8NEZ4	Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000273226	ENST00000609982	RP11-513M16.8	ENSG00000118058	KMT2A	76.65	95.769	Q03164	TF,Epi	NA
ENSG00000273226	ENST00000609982	RP11-513M16.8	ENSG00000168795	ZBTB5	35.99	91.681	O15062	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000273226	ENST00000609982	RP11-513M16.8	ENSG00000198000	NOL8	69.07	91.651	Q76FK4	RBP	NA

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lncRNA-DNA interaction for RP11-513M16.8

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-513M16.8

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

PSMB5,FLII,FIBP,PARP1,RNH1,MRPL37,TUBA1B,SMIM12,PITPNM1,PSMD2,RAB5C,YIF1A,PSMD8,EIF2B3,PRPS1,ATP6V0D1,LIMK1,MAZ,HSPA8,GET3,FAH,NUDT22,PSMC4,LMNA,GALK1,SNRNP40,CENPN,CAPN1,COPG1,GRN,PGAM1,FLAD1,MYDGF,AP2M1,NOMO2,DLGAP5,VARS1,LRP10,PPP1CA,PKM,TAGLN2,ATP13A2,NPLOC4,MAD2L2,ATP6V0B,ACP2,GPR137,CD276,TUBG1,PPIF,IPO13,PUF60,WDR1,CLPB,MRPL4,EIF4G1,GYS1,PRMT5,GAPDH,DPP3,TEAD4,GPN1,ASL,CANT1,CALM3,DNAJC11,RPN2,PSME3,NDUFV1,ENO1,CDC20

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

ORF mutation

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000273226	ENST00000609982	exon_skip_131398	chr15:101286213-101286293	-7.04	-0.1035	SNRPA1	ENST00000254193	Frame-shift
ENSG00000273226	ENST00000609982	exon_skip_370518	chr22:50247691-50247776	-9.63	-0.1235	HDAC10	ENST00000216271	Frame-shift
ENSG00000273226	ENST00000609982	exon_skip_53559	chr10:101793912-101793998	-6.84	-0.1103	OGA	ENST00000361464	Frame-shift
ENSG00000273226	ENST00000609982	exon_skip_111863	chr14:23565815-23565892	-8.84	-0.1579	AP1G2	ENST00000308724,ENST00000397120	Frame-shift
ENSG00000273226	ENST00000609982	exon_skip_111870	chr14:23566561-23566686	-11.15	-0.1343	AP1G2	ENST00000397120	Frame-shift
ENSG00000273226	ENST00000609982	exon_skip_300663	chr19:1425877-1425960	-8.03	-0.1029	DAZAP1	ENST00000233078	Frame-shift
ENSG00000273226	ENST00000609982	exon_skip_319223	chr19:43526200-43526349	-10.17	-0.1883	ETHE1	ENST00000292147	Frame-shift
ENSG00000273226	ENST00000609982	exon_skip_374497	chr3:49999439-49999513	-7.59	-0.1084	RBM6	ENST00000266022	Frame-shift
ENSG00000273226	ENST00000609982	exon_skip_380242	chr3:186784961-186785101	-7.29	-0.4860	EIF4A2	ENST00000323963	Frame-shift
ENSG00000273226	ENST00000609982	exon_skip_382458	chr3:38131595-38131638	-8.69	-2.1725	ACAA1	ENST00000333167	Frame-shift
ENSG00000273226	ENST00000609982	exon_skip_77097	chr11:103082747-103082839	-5.44	-0.1511	DCUN1D5	ENST00000260247	Frame-shift

lncRNA targets by miRNA.

LncRNA Ensembl ID	miRNA ID	LncRNA ENST ID	Binding site in lncRNA	Score	Energy	Align Len	Public source
ENSG00000273226	hsa-mir-877	ENST00000609982	chr9:19375452-19375498	171.00	-69.97	49	NA
ENSG00000273226	hsa-mir-877	ENST00000609982	chr9:19375881-19375977	167.00	-63.29	82	NA
ENSG00000273226	hsa-mir-877	ENST00000609982	chr9:19375784-19375870	159.00	-70.18	69	NA
ENSG00000273226	hsa-mir-877	ENST00000609982	chr9:19375682-19375756	156.00	-62.81	73	NA

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Variants for RP11-513M16.8

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID	LncRNA ENST ID	PC Gene Name	PC Gene ID	PC ENST ID	dG	nDG	Cancer with PC gene up-regulation	Cancer with PC gene Down-regulation
ENSG00000273226	ENST00000609982	CLPB	ENSG00000162129	ENST00000535990	-0.3633	407	UCEC	-
ENSG00000273226	ENST00000609982	CLPB	ENSG00000162129	ENST00000340729	-0.3633	407	UCEC	-
ENSG00000273226	ENST00000609982	CLPB	ENSG00000162129	ENST00000543042	-0.3633	413	UCEC	-
ENSG00000273226	ENST00000609982	GRN	ENSG00000030582	ENST00000053867	-0.2361	1	UCEC	-
ENSG00000273226	ENST00000609982	GRN	ENSG00000030582	ENST00000586242	-0.2361	1	UCEC	-
ENSG00000273226	ENST00000609982	PKM	ENSG00000067225	ENST00000565154	-1.9420	1	UCEC,LUSC	-
ENSG00000273226	ENST00000609982	PKM	ENSG00000067225	ENST00000568459	-2.5750	16	UCEC,LUSC	-
ENSG00000273226	ENST00000609982	CD276	ENSG00000103855	ENST00000561176	-0.8583	23	UCEC,ESCA	-
ENSG00000273226	ENST00000609982	GAPDH	ENSG00000111640	ENST00000396858	-0.1276	1	UCEC,LUSC	-
ENSG00000273226	ENST00000609982	CDC20	ENSG00000117399	ENST00000310955	-0.3327	417	UCEC,ESCA,LUSC	-
ENSG00000273226	ENST00000609982	CDC20	ENSG00000117399	ENST00000372462	-0.3327	417	UCEC,ESCA,LUSC	-
ENSG00000273226	ENST00000609982	ACP2	ENSG00000134575	ENST00000533929	-0.4221	46	UCEC	-
ENSG00000273226	ENST00000609982	ACP2	ENSG00000134575	ENST00000444355	-0.1094	74	UCEC	-
ENSG00000273226	ENST00000609982	ENO1	ENSG00000074800	ENST00000234590	-0.1129	1	UCEC,LUSC	-
ENSG00000273226	ENST00000609982	RPN2	ENSG00000118705	ENST00000437329	-0.1029	234	UCEC	-
ENSG00000273226	ENST00000609982	RPN2	ENSG00000118705	ENST00000456400	-0.3650	5	UCEC	-
ENSG00000273226	ENST00000609982	DPP3	ENSG00000254986	ENST00000530165	-0.1606	57	UCEC,LUSC	-
ENSG00000273226	ENST00000609982	LIMK1	ENSG00000106683	ENST00000538333	-0.1145	1	ESCA	-
ENSG00000273226	ENST00000609982	PPIF	ENSG00000108179	ENST00000472580	-0.1022	1	UCEC,LUSC	-
ENSG00000273226	ENST00000609982	FLAD1	ENSG00000160688	ENST00000315144	-0.1406	27	UCEC,LUSC	-
ENSG00000273226	ENST00000609982	FLAD1	ENSG00000160688	ENST00000292180	-0.1406	27	UCEC,LUSC	-
ENSG00000273226	ENST00000609982	FLAD1	ENSG00000160688	ENST00000368428	-0.1406	27	UCEC,LUSC	-
ENSG00000273226	ENST00000609982	ATP13A2	ENSG00000159363	ENST00000341676	-0.1128	11	UCEC	-
ENSG00000273226	ENST00000609982	VARS1	ENSG00000204394	ENST00000375663	-0.2131	44	UCEC	-
ENSG00000273226	ENST00000609982	ATP6V0B	ENSG00000117410	ENST00000471859	-0.7380	33	UCEC	-
ENSG00000273226	ENST00000609982	ATP6V0B	ENSG00000117410	ENST00000498208	-0.1507	1	UCEC	-
ENSG00000273226	ENST00000609982	PPP1CA	ENSG00000172531	ENST00000358239	-0.1551	1	UCEC	-

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000273226.1	ENST00000609982.1	42	133	5

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential