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lncRNA: ENSG00000272994

Summary for C2orf49-DT

Gene summary

Gene information	Ensembl ID	ENSG00000272994
	Gene symbol	C2orf49-DT
	Gene name	C2orf49 divergent transcript
	HGNC	55178
	Entrez ID
	Gene type	lincRNA
	Synonyms	RP11-332H14.2\|C2orf49-DT\|02q12.2
	UniProtAcc

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Structure and expression level for C2orf49-DT

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID

Base mean

log2FC(AD/control)

lfcSE

Stat

P-value

Adjc.p-value

DEG direction

Cancer type

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID

Correlation

P-value

Cancer Type

Adjc.p-value

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lncRNA-Protein interaction for C2orf49-DT

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000171634	BPTF	58.15	98.3551	Q12830	TF,Epi	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000272333	KMT2B	42.36	97.0035	Q9UMN6	TF,Epi	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000143033	MTF2	10.73	94.1405	Q9Y483	TF,Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000135164	DMTF1	66.33	92.9835	Q9Y222	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000181827	RFX7	65.12	97.0851	Q2KHR2	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000171634	BPTF	58.15	98.3495	Q12830	TF,Epi	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000167232	ZNF91	55.09	97.1718	Q05481	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000099326	MZF1	51.5	95.7114	P28698	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000198521	ZNF43	49.89	95.8499	P17038	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000196670	ZFP62	48.93	96.7761	Q8NB50	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000070476	ZXDC	47.6	95.0409	Q2QGD7	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000272333	KMT2B	42.36	97.0533	Q9UMN6	TF,Epi	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000198040	ZNF84	41.81	96.3868	P51523	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000168795	ZBTB5	38.52	97.1212	O15062	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000186272	ZNF17	35.01	96.2966	P17021	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000166432	ZMAT1	32.36	93.5391	Q5H9K5	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000142065	ZFP14	29.05	95.7022	Q9HCL3	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000256223	ZNF10	24.69	94.762	P21506	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000197857	ZNF44	24.66	95.8591	P15621	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000168661	ZNF30	24.66	95.5691	P17039	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000065029	ZNF76	23.73	95.8108	P36508	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000278129	ZNF8	22.19	95.5755	P17098	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000166526	ZNF3	20.98	95.1729	P17036	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000144161	ZC3H8	18.8	93.5374	Q8N5P1	TF,RBP	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000172466	ZNF24	14.62	92.5987	P17028	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000114126	TFDP2	12.68	96.0667	Q14188	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000167766	ZNF83	12.02	95.9208	P51522	TF	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000143033	MTF2	10.73	93.9215	Q9Y483	TF,Epi	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000105750	ZNF85	8.89	96.1228	Q03923	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000004534	RBM6	73.95	97.0087	P78332	RBP	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000213079	SCAF8	66.96	97.9883	Q9UPN6	RBP	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000163728	TTC14	64.31	93.5447	Q96N46	RBP	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000198000	NOL8	62.17	97.4079	Q76FK4	RBP	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000085872	CHERP	57.27	94.9547	Q8IWX8	RBP	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000135870	RC3H1	43.53	96.4383	Q5TC82	RBP	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000161813	LARP4	39.85	94.8044	Q71RC2	RBP	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000124193	SRSF6	26.43	94.4631	Q13247	RBP	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000184863	RBM33	24.89	91.1889	Q96EV2	RBP	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000164548	TRA2A	22.98	93.9358	Q13595	RBP	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000167978	SRRM2	20.58	98.6233	Q9UQ35	RBP	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000179151	EDC3	19.44	94.4774	Q96F86	RBP	NA
ENSG00000272994	ENST00000610036	RP11-332H14.2	ENSG00000144161	ZC3H8	18.8	93.4023	Q8N5P1	TF,RBP	NA

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lncRNA-DNA interaction for C2orf49-DT

lncRNA targets the enhancer region and positively regulates the gene expression.

Only predicted by TDF

ZNF30,RFX7,CWC22,RBM6,ZC3H8,RBM39,EDC3,TTC14,PUM2,XPO1,RBM5,SRRM2,SRBD1,RC3H1,ZFP62,ZNF44,MZF1,ZNF43,MYSM1,SP3,ZNF17,ZNF91,ZXDC,ZNF84,DMTF1,TIGD1,TRA2A,ADNP,ZNF24,NR2C1,TFDP2,KMT2B,ZMAT1,ZNF83,ZBTB5,THAP9,ZFP14,TSN,NSUN6,RNPC3,ZNF3,ZNF8,THOC1,RBM33,DDX17,NOL8,ZNF10

Exist in public source

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for C2orf49-DT

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

ORF mutation

-lncRNA and exonskipping events are negatively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

LOF

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for C2orf49-DT

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000272994.1	ENST00000610036.1	100	540	238

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential