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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000272645

Summary for RP11-504P24.8

check button Gene summary

Gene informationEnsembl ID

ENSG00000272645

Gene symbol

RP11-504P24.8

Gene name
HGNC
Entrez ID
Gene typelincRNA
Synonyms
UniProtAcc

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Structure and expression level for RP11-504P24.8

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002726452.406745e+021.343892e+001.385431e-019.700171e+003.010000e-222.050000e-21UPKIRC
ENSG000002726452.986321e+021.236379e+002.347211e-015.267437e+001.380000e-071.510000e-06UPBLCA
ENSG000002726453.665073e+021.062614e+002.089596e-015.085260e+003.670000e-071.710000e-06UPKIRP
ENSG000002726452.806932e+021.117652e+001.403795e-017.961644e+001.700000e-158.550000e-15UPLUSC
ENSG000002726452.648848e+021.327866e+001.443208e-019.200794e+003.550000e-203.650000e-19UPLUAD
ENSG000002726451.476141e+021.734838e+002.912933e-015.955641e+002.590000e-096.050000e-08UPREAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002726455.460797e-011.043691e-04CHOL3.091446e-04

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lncRNA-Protein interaction for RP11-504P24.8

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000101126ADNP52.7894.5434Q9H2P0TF,EpiNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000104885DOT1L47.2591.7452Q8TEK3TF,EpiNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000010803SCMH137.594.6721Q96GD3TF,EpiNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000155363MOV1071.0795.1756Q9HCE1RBP,EpiNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000277258PCGF215.7390.8603P35227TF,EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000168152THAP976.0291.9616Q9H5L6TFNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000101126ADNP52.7894.6215Q9H2P0TF,EpiNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000104885DOT1L47.2590.1143Q8TEK3TF,EpiNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000010803SCMH137.594.6894Q96GD3TF,EpiNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000025156HSF224.7793.7866Q03933TFNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000148200NR6A115.6693.1992Q15406TFNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000256223ZNF1011.9992.9765P21506TFNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000120798NR2C19.5791.6205P13056TFNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000177463NR2C29.4490.1038P49116TFNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000196378ZNF348.0390.3047Q8IZ26TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000155363MOV1071.0793.4103Q9HCE1RBP,EpiNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000013573DDX1163.3693.9546Q96FC9RBPNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000122965RBM1956.2894.6732Q9Y4C8RBPNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000106344RBM2853.1390.5909Q9NW13RBPNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000082898XPO152.1890.384O14980RBPNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000079134THOC148.1294.0977Q96FV9RBPNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000071894CPSF147.9895.5563Q10570RBPNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000176102CSTF347.9194.9115Q12996RBPNA
ENSG00000272645ENST00000608760RP11-504P24.8ENSG00000111364DDX558.3392.5642Q8NHQ9RBPNA

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lncRNA-DNA interaction for RP11-504P24.8

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
ZNF30,RBM19,ILF3,GLI4,RBM39,EDC3,MYPOP,CIRBP,MZF1,MYSM1,AKAP8,ZNF2,ZXDC,SUGP2,DMTF1,ZNF77,RBM28,ZNF74,DDX55,KMT2B,STAT2,NR6A1,RNPC3,ZFP69,SAFB2,THOC1,MNT,CHTOP,TFAP4,DDX59,LSM5,ZBED5,CENPT,TTC14,ZGLP1,MRM1,SUGP1,ZNF44,RBM4B,RBPMS,CSTF3,RBM26,CPSF1,RNPS1,RBM14,NR2F6,ZBTB3,GZF1,ADNP,MYEF2,CWC15,SURF6,NFYC,DHX34,PPIE,CPSF7,IRF7,THAP9,THOC2,USF1,CXXC1,ZNF34,THAP6,MOV10,DDX17,E2F5,SRRM2,E2F6,ZNF22,PHF1,THYN1,ZC3H8,HSF4,THOC6,ZFP62,SGSM2,CELF1,SCMH1,ELK4,RBM45,TIGD1,DDX51,PCBP4,SRSF2,MBD6,DDX31,ZGPAT,PBX4,ZMAT1,ZNF83,NSUN6,ZNF3,NXF1,ZNF18,NR2C2,PCGF2,DDX11,TGIF1,RBM6,HMGN3,ZNF14,KHDC1,NOP2,RBM48,GMEB2,NOL3,XPO1,RBM5,SRCAP,DOT1L,ZNF84,DDX42,BAZ2B,TRA2A,RBM8A,ZNF69,NR2C1,ZFP3,SFPQ,RBM33,NOL8,ZNF10
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-504P24.8

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000272645ENST00000608760exon_skip_1234chr1:11658532-11658628-20.33-0.2337FBXO44ENST00000251547,ENST00000376770In-frame
ENSG00000272645ENST00000608760exon_skip_470077chr7:102397619-102397698-12.44-0.1829PRKRIP1ENST00000397912,ENST00000496391Frame-shift

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000272645ENST00000608760exon_skip_62623chr11:69079833-69079883-11.91-0.3503TPCN2ENST00000294309Frame-shift
ENSG00000272645ENST00000608760exon_skip_66482chr11:126274926-126275021-13.99-0.2028FOXRED1ENST00000263578Frame-shift
ENSG00000272645ENST00000608760exon_skip_111863chr14:23565815-23565892-15.22-0.2416AP1G2ENST00000308724,ENST00000397120Frame-shift
ENSG00000272645ENST00000608760exon_skip_302168chr19:10680345-10680443-13.65-0.1500ILF3ENST00000590261Frame-shift
ENSG00000272645ENST00000608760exon_skip_327433chr2:86125794-86125880-9.48-0.1317PTCD3ENST00000254630Frame-shift
ENSG00000272645ENST00000608760exon_skip_370518chr22:50247691-50247776-15.09-0.2125HDAC10ENST00000216271Frame-shift
ENSG00000272645ENST00000608760exon_skip_377198chr3:123130479-123130616-14.75-0.1143PDIA5ENST00000316218Frame-shift
ENSG00000272645ENST00000608760exon_skip_382458chr3:38131595-38131638-8.65-0.2218ACAA1ENST00000333167Frame-shift
ENSG00000272645ENST00000608760exon_skip_446758chr5:178212972-178213103-19.47-0.2049PHYKPLENST00000308158Frame-shift
ENSG00000272645ENST00000608760exon_skip_499567chr9:128325142-128325239-18.95-0.1974COQ4ENST00000300452Frame-shift
ENSG00000272645ENST00000608760exon_skip_5818chr1:45568484-45568684-20.38-0.1056AKR1A1ENST00000351829,ENST00000372070Frame-shift
ENSG00000272645ENST00000608760exon_skip_11029chr1:154989559-154989707-24.88-0.1790FLAD1ENST00000292180Frame-shift
ENSG00000272645ENST00000608760exon_skip_41813chr10:68337857-68337996-23.27-0.2006HNRNPH3ENST00000265866Frame-shift
ENSG00000272645ENST00000608760exon_skip_66185chr11:124626472-124626609-18.92-0.1564TBRG1ENST00000441174Frame-shift
ENSG00000272645ENST00000608760exon_skip_92074chr12:50142052-50142110-6.97-0.1742CERS5ENST00000317551Frame-shift
ENSG00000272645ENST00000608760exon_skip_95407chr12:95040475-95040597-13.36-0.1152NR2C1ENST00000333003Frame-shift
ENSG00000272645ENST00000608760exon_skip_133217chr16:8635038-8635079-13.73-0.3613METTL22ENST00000381920Frame-shift
ENSG00000272645ENST00000608760exon_skip_309204chr19:49181348-49181461-24.18-0.2159TRPM4ENST00000252826Frame-shift
ENSG00000272645ENST00000608760exon_skip_319223chr19:43526200-43526349-24.05-0.2227ETHE1ENST00000292147Frame-shift
ENSG00000272645ENST00000608760exon_skip_340759chr2:85552415-85552567-19.70-0.1407GGCXENST00000233838Frame-shift
ENSG00000272645ENST00000608760exon_skip_358821chr20:63943652-63943669-6.35-0.4885UCKL1ENST00000354216Frame-shift
ENSG00000272645ENST00000608760exon_skip_374551chr3:50100531-50100605-14.00-0.2373RBM5ENST00000347869Frame-shift
ENSG00000272645ENST00000608760exon_skip_380242chr3:186784961-186785101-15.64-0.1282EIF4A2ENST00000323963Frame-shift
ENSG00000272645ENST00000608760exon_skip_436035chr5:79656957-79657001-6.15-0.1662TENT2ENST00000296783,ENST00000428308,ENST00000453514Frame-shift
ENSG00000272645ENST00000608760exon_skip_442657chr5:74730259-74730398-15.95-0.2658GFM2ENST00000296805,ENST00000509430Frame-shift
ENSG00000272645ENST00000608760exon_skip_446770chr5:178215275-178215430-19.36-0.1249PHYKPLENST00000308158Frame-shift
ENSG00000272645ENST00000608760exon_skip_477099chr7:92509328-92509411-10.87-0.1510PEX1ENST00000248633Frame-shift
ENSG00000272645ENST00000608760exon_skip_4796chr1:41007448-41007545-14.98-0.2203CTPS1ENST00000372616,ENST00000372621Frame-shift
ENSG00000272645ENST00000608760exon_skip_7523chr1:78660553-78660654-12.34-0.1469IFI44ENST00000370747Frame-shift
ENSG00000272645ENST00000608760exon_skip_9446chr1:147270931-147271005-10.09-0.2402CHD1LENST00000369258Frame-shift
ENSG00000272645ENST00000608760exon_skip_16568chr1:201989382-201989531-15.47-0.1105RNPEPENST00000295640Frame-shift
ENSG00000272645ENST00000608760exon_skip_41841chr10:68756272-68756483-19.61-0.1114CCAR1ENST00000265872Frame-shift
ENSG00000272645ENST00000608760exon_skip_52701chr10:97468965-97469104-17.96-0.1460MMS19ENST00000370782,ENST00000438925Frame-shift
ENSG00000272645ENST00000608760exon_skip_53559chr10:101793912-101793998-13.04-0.1716OGAENST00000361464Frame-shift
ENSG00000272645ENST00000608760exon_skip_58412chr11:43892040-43892129-8.92-0.1075ALKBH3ENST00000302708Frame-shift
ENSG00000272645ENST00000608760exon_skip_59071chr11:47234756-47234934-16.61-0.1115DDB2ENST00000256996Frame-shift
ENSG00000272645ENST00000608760exon_skip_74009chr11:64773429-64773505-16.00-0.2462SF1ENST00000377390Frame-shift
ENSG00000272645ENST00000608760exon_skip_103007chr13:37025319-37025437-13.91-0.1464SUPT20HENST00000350612Frame-shift
ENSG00000272645ENST00000608760exon_skip_114365chr14:74290026-74290118-18.45-0.2754ABCD4ENST00000356924Frame-shift
ENSG00000272645ENST00000608760exon_skip_139933chr16:90035632-90035687-9.23-0.2495GAS8ENST00000268699Frame-shift
ENSG00000272645ENST00000608760exon_skip_287763chr17:28884224-28884315-18.77-0.2888FLOT2ENST00000394908Frame-shift
ENSG00000272645ENST00000608760exon_skip_290158chr17:42953723-42953778-11.54-0.2263AARSD1ENST00000427569Frame-shift
ENSG00000272645ENST00000608760exon_skip_313557chr19:5786748-5786845-17.51-0.1946DUS3LENST00000309061Frame-shift
ENSG00000272645ENST00000608760exon_skip_335558chr2:240596680-240596942-28.39-0.1113CAPN10ENST00000391984Frame-shift
ENSG00000272645ENST00000608760exon_skip_353131chr20:58669290-58669453-25.76-0.2576STX16ENST00000371141Frame-shift
ENSG00000272645ENST00000608760exon_skip_364260chr22:29291561-29291599-9.48-0.2963EWSR1ENST00000397938Frame-shift
ENSG00000272645ENST00000608760exon_skip_365497chr22:38067703-38067770-12.97-0.4323PICK1ENST00000356976,ENST00000404072Frame-shift
ENSG00000272645ENST00000608760exon_skip_374497chr3:49999439-49999513-13.21-0.2752RBM6ENST00000266022Frame-shift
ENSG00000272645ENST00000608760exon_skip_378467chr3:143023974-143024018-8.77-0.2139U2SURPENST00000473835Frame-shift
ENSG00000272645ENST00000608760exon_skip_438188chr5:141638954-141639021-13.41-0.2629RELL2ENST00000297164,ENST00000444782Frame-shift
ENSG00000272645ENST00000608760exon_skip_441368chr5:32380074-32380172-14.04-0.2380ZFRENST00000265069Frame-shift
ENSG00000272645ENST00000608760exon_skip_444499chr5:138164086-138164133-7.41-0.1807BRD8ENST00000254900Frame-shift
ENSG00000272645ENST00000608760exon_skip_445390chr5:150403120-150403312-21.95-0.1372CD74ENST00000009530In-frame
ENSG00000272645ENST00000608760exon_skip_470226chr7:103307595-103307708-12.91-0.1218PMPCBENST00000249269Frame-shift
ENSG00000272645ENST00000608760exon_skip_511212chrX:71555189-71555385-20.40-0.1068OGTENST00000373719Frame-shift
ENSG00000272645ENST00000608760exon_skip_374581chr3:50110378-50110463-10.28-0.1512RBM5ENST00000347869Frame-shift
ENSG00000272645ENST00000608760exon_skip_297191chr18:62280359-62280442-14.26-0.2502RELCHENST00000398130Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RP11-504P24.8

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name
LncEditing_22920ENSG00000272645.2chr1223953239-lincRNARP11-504P24.8ENST00000608760.2lincRNARP11-504P24.8-001
LncEditing_22929ENSG00000272645.2chr1223953351-lincRNARP11-504P24.8ENST00000608760.2lincRNARP11-504P24.8-001

check buttonEdited-associated DElncRNAs in cancer.
Differentially expressed gene
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange
ENSG00000272645LncEditing_22929GBMchr1_223953351_-5.697471e+002.513593e+008.470478e-017.535044e+004.881694e-146.268715e-13UP
ENSG00000272645LncEditing_22929OVchr1_223953351_-6.816589e+003.831677e+001.203262e+008.727444e+002.604933e-181.008520e-17UP
ENSG00000272645LncEditing_22920ESCAchr1_223953239_-6.760747e+003.574044e+001.087400e+004.958466e+007.105204e-071.162569e-06UP
ENSG00000272645LncEditing_22929ESCAchr1_223953351_-5.407274e+003.337601e+001.436596e+005.185445e+002.154991e-073.831096e-07UP

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA-RBP complex negative regulation
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type
ENSG00000272645ENSG00000079134THOC1exon_skip_370518ENSG00000100429:chr22:50247691-50247776HDAC10ENST00000216271Frame-shiftSARC,UVM,SKCM,READ,PRAD,PCPG,PAAD,THCA
ENSG00000272645ENSG00000079134THOC1exon_skip_377198ENSG00000065485:chr3:123130479-123130616PDIA5ENST00000316218Frame-shiftSARC,UVM,UCS,PCPG,PAAD,TGCT
ENSG00000272645ENSG00000111364DDX55exon_skip_382458ENSG00000060971:chr3:38131595-38131638ACAA1ENST00000333167Frame-shiftSTAD,UVM,SKCM,READ,OV,PAAD,THCA
ENSG00000272645ENSG00000079134THOC1exon_skip_382458ENSG00000060971:chr3:38131595-38131638ACAA1ENST00000333167Frame-shiftSARC,STAD,UVM,SKCM,READ,MESO,PRAD,UCS,PCPG,PAAD,TGCT,THCA
ENSG00000272645ENSG00000111364DDX55exon_skip_380242ENSG00000156976:chr3:186784961-186785101EIF4A2ENST00000323963Frame-shiftSTAD,READ,PRAD,PAAD,THCA
ENSG00000272645ENSG00000079134THOC1exon_skip_442657ENSG00000164347:chr5:74730259-74730398GFM2ENST00000296805,ENST00000509430Frame-shiftUVM,SKCM,READ,UCS,PCPG,PAAD,THCA
ENSG00000272645ENSG00000079134THOC1exon_skip_53559ENSG00000198408:chr10:101793912-101793998OGAENST00000361464Frame-shiftUVM,PCPG,PAAD,TGCT,THCA
ENSG00000272645ENSG00000079134THOC1exon_skip_470226ENSG00000105819:chr7:103307595-103307708PMPCBENST00000249269Frame-shiftUVM,SKCM,LIHC,UCS,PCPG,PAAD,TGCT,THCA

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000272645.2ENST00000608760.26169254