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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000272468

Summary for RP1-86C11.7

check button Gene summary

Gene informationEnsembl ID

ENSG00000272468

Gene symbol

RP1-86C11.7

Gene name
HGNC
Entrez ID
Gene typelincRNA
Synonyms
UniProtAcc

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Structure and expression level for RP1-86C11.7

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002724682.427131e+014.415378e+008.811055e-015.011180e+005.410000e-073.750000e-06UPCHOL
ENSG000002724686.676715e+012.899564e+003.741655e-017.749415e+009.230000e-153.980000e-13UPBLCA
ENSG000002724681.458553e+023.463653e+008.344320e-014.150911e+003.310000e-054.848910e-04UPCESC
ENSG000002724684.522601e+011.811190e+002.343822e-017.727504e+001.100000e-141.350000e-13UPHNSC
ENSG000002724684.596082e+012.354156e+002.700984e-018.715920e+002.880000e-184.080000e-17UPUCEC
ENSG000002724687.784723e+012.718048e+004.779444e-015.686955e+001.290000e-086.760000e-07UPESCA
ENSG000002724683.721427e+012.105207e+002.343416e-018.983495e+002.620000e-191.640000e-18UPLUSC
ENSG000002724685.636921e+012.308485e+001.525264e-011.513499e+019.520000e-522.150000e-50UPBRCA
ENSG000002724683.710175e+011.449870e+002.814625e-015.151201e+002.590000e-071.910000e-06UPSTAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002724685.739005e-013.762381e-05CHOL1.543494e-04

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lncRNA-Protein interaction for RP1-86C11.7

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for RP1-86C11.7

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP1-86C11.7

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RP1-86C11.7

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name
LncEditing_164206ENSG00000272468.1chr627122863-lincRNARP1-86C11.7ENST00000607175.1lincRNARP1-86C11.7-001
LncEditing_164215ENSG00000272468.1chr627122938-lincRNARP1-86C11.7ENST00000607175.1lincRNARP1-86C11.7-001
LncEditing_164216ENSG00000272468.1chr627122942-lincRNARP1-86C11.7ENST00000607175.1lincRNARP1-86C11.7-001
LncEditing_164217ENSG00000272468.1chr627122945-lincRNARP1-86C11.7ENST00000607175.1lincRNARP1-86C11.7-001
LncEditing_164219ENSG00000272468.1chr627122954-lincRNARP1-86C11.7ENST00000607175.1lincRNARP1-86C11.7-001
LncEditing_164220ENSG00000272468.1chr627122959-lincRNARP1-86C11.7ENST00000607175.1lincRNARP1-86C11.7-001
LncEditing_164222ENSG00000272468.1chr627122971-lincRNARP1-86C11.7ENST00000607175.1lincRNARP1-86C11.7-001
LncEditing_164223ENSG00000272468.1chr627122972-lincRNARP1-86C11.7ENST00000607175.1lincRNARP1-86C11.7-001
LncEditing_164237ENSG00000272468.1chr627123211-lincRNARP1-86C11.7ENST00000607175.1lincRNARP1-86C11.7-001
LncEditing_164239ENSG00000272468.1chr627123220-lincRNARP1-86C11.7ENST00000607175.1lincRNARP1-86C11.7-001

check buttonEdited-associated DElncRNAs in cancer.
Differentially expressed gene
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange
ENSG00000272468LncEditing_164215THYMchr6_27122938_-3.839817e+001.677845e+008.372208e-016.885759e+005.748039e-129.440719e-11UP
ENSG00000272468LncEditing_164220THYMchr6_27122959_-3.975308e+001.802695e+008.764922e-016.096495e+001.084197e-098.097517e-09UP
ENSG00000272468LncEditing_164222THYMchr6_27122971_-3.981516e+001.953598e+009.735354e-014.439915e+008.999456e-061.958918e-05UP
ENSG00000272468LncEditing_164223OVchr6_27122972_-3.756768e+001.789218e+009.344375e-017.324132e+002.404495e-135.661801e-13UP
ENSG00000272468LncEditing_164237OVchr6_27123211_-3.708128e+001.875275e+001.016685e+006.530608e+006.550314e-111.214317e-10UP
ENSG00000272468LncEditing_164216TGCTchr6_27122942_-1.193624e+015.088000e+008.128905e-014.895892e+009.786058e-071.695974e-06UP
ENSG00000272468LncEditing_164219TGCTchr6_27122954_-1.201182e+015.177293e+008.235976e-014.723333e+002.320104e-063.826300e-06UP
ENSG00000272468LncEditing_164239TGCTchr6_27123220_-1.029144e+014.749815e+008.964581e-015.895096e+003.744626e-099.703470e-09UP
ENSG00000272468LncEditing_164206PRADchr6_27122863_-6.378305e+002.764556e+008.291014e-011.366051e+011.747463e-425.163753e-41UP
ENSG00000272468LncEditing_164222PRADchr6_27122971_-6.253557e+002.872952e+008.911519e-011.249206e+018.249442e-361.283005e-34UP
ENSG00000272468LncEditing_164239PRADchr6_27123220_-6.796641e+003.338596e+009.750576e-018.582172e+009.309800e-182.990267e-17UP
ENSG00000272468LncEditing_164223ESCAchr6_27122972_-4.106130e+001.840298e+008.636775e-014.300836e+001.701552e-052.326453e-05UP

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value
ENSG00000272468LncEditing_164206-3.611645e-011.536309e-045.572496e-04
ENSG00000272468LncEditing_164216-3.209364e-011.912453e-022.095971e-02
ENSG00000272468LncEditing_164217-3.439314e-011.013951e-021.246614e-02
ENSG00000272468LncEditing_164219-3.910532e-012.403708e-034.043446e-03
ENSG00000272468LncEditing_164223-3.416012e-011.415369e-021.615419e-02
ENSG00000272468LncEditing_164237-6.114918e-015.801146e-052.766700e-04
ENSG00000272468LncEditing_164216-5.304063e-011.948036e-022.996233e-02
ENSG00000272468LncEditing_164219-5.809150e-011.446988e-022.480550e-02
ENSG00000272468LncEditing_164222-4.942421e-015.981932e-059.571091e-04
ENSG00000272468LncEditing_164222-5.108430e-012.540965e-023.557351e-02
ENSG00000272468LncEditing_164206-4.221389e-012.516980e-034.094442e-03
ENSG00000272468LncEditing_164217-4.666156e-013.146359e-031.027566e-02
ENSG00000272468LncEditing_164219-3.583364e-014.059179e-024.430632e-02
ENSG00000272468LncEditing_164239-4.433036e-014.171202e-031.197061e-02
ENSG00000272468LncEditing_164216-5.571673e-015.432223e-086.901591e-07
ENSG00000272468LncEditing_164239-3.983557e-019.891744e-031.391205e-02

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000272468.1ENST00000607175.131111206