lncRNA targets the enhancer region and positively regulates the gene expression. |
lncRNA targets the promoter region and positively regulates the gene expression. |
lncRNA targets the promoter region and negatively regulates the gene expression. |
lncRNA targets the 3'UTR region and negatively regulates the mRNA. |
| Only predicted by lncTar | | IQGAP1,CPSF2,YIPF5,PLIN3,CRAT,TUBA1B,OGDH,MCFD2,G3BP2,ALAS1,MYOF | | Exist in public source | | NA |
lncRNA targets the skipped exon region. | | -lncRNA and exonskipping events are positively correlated. |
| LncRNA Ensembl ID | LncRNA ENST ID | Exon ID | Skipped Exon | dG | ndG | Gene name with skipped exon | TransID with skipped exon | ORF mutation |
| -lncRNA and exonskipping events are negatively correlated. |
| LncRNA Ensembl ID | LncRNA ENST ID | Exon ID | Skipped Exon | dG | ndG | Gene name with skipped exon | TransID with skipped exon | LOF | | ENSG00000269918 | ENST00000602575 | exon_skip_41813 | chr10:68337857-68337996 | -15.78 | -0.1360 | HNRNPH3 | ENST00000265866 | Frame-shift | | ENSG00000269918 | ENST00000602575 | exon_skip_290158 | chr17:42953723-42953778 | -9.40 | -0.2611 | AARSD1 | ENST00000427569 | Frame-shift | | ENSG00000269918 | ENST00000602575 | exon_skip_377198 | chr3:123130479-123130616 | -18.49 | -0.1411 | PDIA5 | ENST00000316218 | Frame-shift | | ENSG00000269918 | ENST00000602575 | exon_skip_382458 | chr3:38131595-38131638 | -12.77 | -0.3547 | ACAA1 | ENST00000333167 | Frame-shift | | ENSG00000269918 | ENST00000602575 | exon_skip_470226 | chr7:103307595-103307708 | -13.54 | -0.1341 | PMPCB | ENST00000249269 | Frame-shift | | ENSG00000269918 | ENST00000602575 | exon_skip_445390 | chr5:150403120-150403312 | -21.79 | -0.1165 | CD74 | ENST00000009530 | In-frame |
lncRNA targets by miRNA. |
| LncRNA Ensembl ID | miRNA ID | LncRNA ENST ID | Binding site in lncRNA | Score | Energy | Align Len | Public source |
RNA A-to-I editing events in lncRNA. |
| LncRNAediting ID | LncRNA Ensembl ID | Chromosome | Editing Position | Strand | Gene Type | Gene Name | Transcript ID | Transcript Type | Transcript Name | | LncEditing_199980 | ENSG00000269918.1 | chr8 | 11106493 | - | sense_intronic | AF131215.9 | ENST00000602575.1 | sense_intronic | AF131215.9-001 | | LncEditing_199983 | ENSG00000269918.1 | chr8 | 11106592 | - | sense_intronic | AF131215.9 | ENST00000602575.1 | sense_intronic | AF131215.9-001 | | LncEditing_199984 | ENSG00000269918.1 | chr8 | 11106604 | - | sense_intronic | AF131215.9 | ENST00000602575.1 | sense_intronic | AF131215.9-001 | | LncEditing_199985 | ENSG00000269918.1 | chr8 | 11106605 | - | sense_intronic | AF131215.9 | ENST00000602575.1 | sense_intronic | AF131215.9-001 | | LncEditing_199987 | ENSG00000269918.1 | chr8 | 11106614 | - | sense_intronic | AF131215.9 | ENST00000602575.1 | sense_intronic | AF131215.9-001 | | LncEditing_199988 | ENSG00000269918.1 | chr8 | 11106619 | - | sense_intronic | AF131215.9 | ENST00000602575.1 | sense_intronic | AF131215.9-001 | | LncEditing_199999 | ENSG00000269918.1 | chr8 | 11106701 | - | sense_intronic | AF131215.9 | ENST00000602575.1 | sense_intronic | AF131215.9-001 | | LncEditing_200000 | ENSG00000269918.1 | chr8 | 11106702 | - | sense_intronic | AF131215.9 | ENST00000602575.1 | sense_intronic | AF131215.9-001 |
Edited-associated DElncRNAs in cancer. |
 |
| LncRNA Ensembl ID | LncRNA Index | Cancer Type | Chr_Postion_Strand | AVE1 | AVE2 | log2FC | W-value | P-value | Adjc.p-value | Change | | ENSG00000269918 | LncEditing_199983 | GBM | chr8_11106592_- | 3.354374e+00 | 2.210507e+00 | 1.662051e+00 | 5.219332e+00 | 1.795692e-07 | 3.969167e-07 | UP | | ENSG00000269918 | LncEditing_199984 | GBM | chr8_11106604_- | 3.313339e+00 | 2.304572e+00 | 1.909173e+00 | 4.334709e+00 | 1.459534e-05 | 2.371010e-05 | UP | | ENSG00000269918 | LncEditing_199985 | GBM | chr8_11106605_- | 3.307929e+00 | 2.172279e+00 | 1.648210e+00 | 5.616432e+00 | 1.949408e-08 | 5.054715e-08 | UP | | ENSG00000269918 | LncEditing_199987 | GBM | chr8_11106614_- | 3.327013e+00 | 1.704883e+00 | 1.036747e+00 | 8.292549e+00 | 1.108474e-16 | 2.637517e-15 | UP | | ENSG00000269918 | LncEditing_199988 | GBM | chr8_11106619_- | 3.492922e+00 | 2.337461e+00 | 1.725648e+00 | 3.909275e+00 | 9.257338e-05 | 1.300831e-04 | UP | | ENSG00000269918 | LncEditing_199999 | GBM | chr8_11106701_- | 4.270078e+00 | 2.290732e+00 | 1.113024e+00 | 4.408162e+00 | 1.042516e-05 | 1.735381e-05 | UP | | ENSG00000269918 | LncEditing_200000 | GBM | chr8_11106702_- | 3.801633e+00 | 1.985815e+00 | 1.067364e+00 | 7.268736e+00 | 3.628658e-13 | 3.433840e-12 | UP | | ENSG00000269918 | LncEditing_199983 | LGG | chr8_11106592_- | 5.043683e+00 | 3.918642e+00 | 2.746318e+00 | 5.760637e+00 | 8.379732e-09 | 1.157748e-08 | UP | | ENSG00000269918 | LncEditing_199980 | PCPG | chr8_11106493_- | 5.330632e+00 | 3.894440e+00 | 2.208037e+00 | 2.628853e+00 | 8.567332e-03 | 9.615989e-03 | UP | | ENSG00000269918 | LncEditing_199983 | PCPG | chr8_11106592_- | 5.374941e+00 | 3.793778e+00 | 1.989600e+00 | 3.810574e+00 | 1.386447e-04 | 1.930697e-04 | UP | | ENSG00000269918 | LncEditing_199983 | THCA | chr8_11106592_- | 5.790977e+00 | 4.524272e+00 | 2.808034e+00 | 6.866081e+00 | 6.598952e-12 | 1.357562e-11 | UP | | ENSG00000269918 | LncEditing_199983 | PRAD | chr8_11106592_- | 3.153133e+00 | 2.522698e+00 | 3.107344e+00 | 4.475586e+00 | 7.620216e-06 | 1.023534e-05 | UP |
Correlation between RNA A-to-I editing events's frequecy and lncRNA expression. |
| LncRNA Ensembl ID | LncRNA Index | Correlation | P-value | Adjc.p-value | | ENSG00000269918 | LncEditing_199983 | -3.571735e-01 | 1.363633e-07 | 8.103879e-07 | | ENSG00000269918 | LncEditing_199983 | -3.281472e-01 | 3.169161e-02 | 4.629798e-02 | | ENSG00000269918 | LncEditing_199983 | -3.483880e-01 | 3.967186e-05 | 8.331090e-05 |
Cis-expression quantitative trait loci(cis-eQTL) of lncRNA. |
| LncRNA Ensembl ID | LncRNA Name | SNP info | Number of Positive corelated Cancer | Positive corelated Cancer | Number of Negative corelated Cancer | Negative corelated Cancer |
lncRNA regulates differentially expressed genes by function as enhancer. |
| LncRNA Ensembl ID | PC Gene ID | PC Gene Name | Positive correlated cancers | Cancer with PC gene up-regulation | Cancer with PC gene down-regulation |
LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5). |
| lncRNA ID | TF ID | TF Name | PCgene ID | PCgene Name | Number of Cancer | Canaer Types |
LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5). |
| lncRNA ID | TF ID | TF Name | PCgene ID | PCgene Name | Number of Cancer | Canaer Types |
LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region. |
| LncRNA Ensembl ID | RBP ID | RBP Gene Name | Exon Skipping ID | Skipped Exon | EX Gene Name | EX Affected TransID | ORF_anno | Cancer Type |
LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region. |
| LncRNA Ensembl ID | RBP ID | RBP Gene Name | Exon Skipping ID | Skipped Exon | EX Gene Name | EX Affected TransID | ORF_anno | Cancer Type |
lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region. |
| LncRNA Ensembl ID | LncRNA ENST ID | PC Gene Name | PC Gene ID | PC ENST ID | dG | nDG | Cancer with PC gene up-regulation | Cancer with PC gene Down-regulation | | ENSG00000269918 | ENST00000602575 | ALAS1 | ENSG00000023330 | ENST00000394965 | -0.1562 | 1147 | - | CHOL | | ENSG00000269918 | ENST00000602575 | ALAS1 | ENSG00000023330 | ENST00000310271 | -0.1562 | 1147 | - | CHOL | | ENSG00000269918 | ENST00000602575 | ALAS1 | ENSG00000023330 | ENST00000484952 | -0.1562 | 1147 | - | CHOL | | ENSG00000269918 | ENST00000602575 | ALAS1 | ENSG00000023330 | ENST00000493402 | -0.4575 | 927 | - | CHOL | | ENSG00000269918 | ENST00000602575 | CRAT | ENSG00000095321 | ENST00000455396 | -0.1487 | 168 | - | CHOL |
lncRNA regulates mRNA by competing the miRNA binding site with mRNA. |
| LncRNA Ensembl ID | lncRNA-miRNA-mRNA | Cancer Types |
ORFfinder result for the gencode.v22.lncRNA.transcript.fa. |
| lncRNA Ensembl ID | lncRNA ENST ID | length(AA) | start at transcript | end at transcript | | ENSG00000269918.1 | ENST00000602575.1 | 93 | 256 | 537 |
|