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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000268713

Summary for CTC-444N24.8

check button Gene summary

Gene informationEnsembl ID

ENSG00000268713

Gene symbol

CTC-444N24.8

Gene name
HGNC
Entrez ID
Gene typelincRNA
Synonyms
UniProtAcc

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Structure and expression level for CTC-444N24.8

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002687132.342570e+021.163743e+009.213172e-021.263129e+011.420000e-361.980000e-35UPKIRC
ENSG000002687132.071923e+021.475546e+001.809782e-018.153165e+003.550000e-164.010000e-15UPKICH
ENSG000002687132.200075e+021.214071e+001.479477e-018.206080e+002.290000e-163.710000e-15UPKIRP

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002687135.674336e-014.808724e-05CHOL1.805418e-04
ENSG000002687133.908722e-011.523650e-04KICH2.470950e-04
ENSG000002687134.104129e-014.185996e-26KIRC9.188771e-25

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lncRNA-Protein interaction for CTC-444N24.8

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000070495JMJD64.9890.909Q6NYC1RBP,EpiNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000277258PCGF25.3690.6394P35227TF,EpiNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000136450SRSF11.0490.0784Q07955RBP,EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000130254SAFB287.8891.9283Q14151TF,RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000196867ZFP2879.5991.4149Q8NHY6TFNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000105127AKAP878.7393.3039O43823TFNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000196670ZFP6253.3590.4896Q8NB50TFNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000198040ZNF8446.2692.9286P51523TFNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000186272ZNF1729.5890.7842P17021TFNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000105708ZNF1422.8790.7248P17017TFNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000179886TIGD514.7691.159Q53EQ6TFNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000185252ZNF7411.1690.3312Q16587TF,RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000172273HINFP4.7991.3547Q9BQA5TF,EpiNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000256223ZNF103.7290.8083P21506TFNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000278129ZNF81.6991.8578P17098TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000111641NOP293.5592.6682P46087RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000130254SAFB287.8893.7595Q14151TF,RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000004534RBM686.1993.1533P78332RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000135870RC3H154.8294.7178Q5TC82RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000079134THOC152.1890.2678Q96FV9RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000129351ILF339.8594.2747Q12906RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000184863RBM3322.6890.9925Q96EV2RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000116350SRSF416.4193.1021Q08170RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000185252ZNF7411.1690.1083Q16587TF,RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000164548TRA2A7.3491.0284Q13595RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000148296SURF66.4391.2456O75683RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000070495JMJD64.9892.3789Q6NYC1RBP,EpiNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000111364DDX554.0694.0296Q8NHQ9RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000134597RBMX23.8690.395Q9Y388RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000204356NELFE3.2291.4061P18615RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000101361NOP562.890.7385O00567RBPNA
ENSG00000268713ENST00000600047CTC-444N24.8ENSG00000136450SRSF11.0490.2358Q07955RBP,EpiNA

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lncRNA-DNA interaction for CTC-444N24.8

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
ZNF30,SLIRP,ILF3,GLI4,RBM39,MYPOP,IRF3,JMJD6,CIRBP,DDX56,IMP3,TIGD5,MZF1,NRF1,AKAP8,ZNF74,DDX55,ZFP14,ZFP69,SAFB2,THOC1,LSM5,ZBED5,PA2G4,CENPT,TTC14,ZGLP1,RC3H1,SUGP1,SRSF4,DBP,LSM4,RBM4B,U2AF2,CSTF3,PUS3,CPSF1,RNPS1,NR2F6,ZBTB3,CWC15,SURF6,DHX34,RBM15,PPIE,SF3B6,NELFE,IRF7,USF1,CXXC1,ZNF71,MOV10,HSF1,ZNF22,PHF1,THYN1,ZC3H8,DEAF1,DDX49,HSF4,THOC6,RBM42,ZFP62,MEX3D,ZNF48,ATF4,SF3B4,REXO4,TIGD1,DDX51,MBD3,E2F4,PCBP4,THAP3,SRSF2,DDX31,EIF3B,PBX4,ZNF83,ZNF3,ZNF8,ZNF18,PCGF2,TGIF1,ETV2,SOX12,ZNF14,NOP2,GMEB2,THAP8,LSM2,ZFP28,ZNF17,ZNF84,PIN1,TRA2A,RRP7A,SMYD3,HINFP,THOC7,RALY,RBM33,NOL8,ZNF10
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.
Only predicted by TDF
ZNF48,RRP7A,MZF1,LSM2,U2AF2,ZNF14,ZNF3,SRP14,ZNF83,RBM42,RBM6,PBX4,THAP3,CIRBP,TGIF1
Exist in public source
NA

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.
Only predicted by TDF
GLMP,GTF2I,SMAD1,ADAT1,SF3A1,PATL1,ASCC1,STAU1,AKAP1
Exist in public source
NA

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lncRNA-RNA interaction for CTC-444N24.8

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
EHF,PUM1,BAZ2A,HBP1,KLF13
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000268713ENST00000600047exon_skip_13601chr1:164820071-164820184-14.17-0.2180PBX1ENST00000420696Frame-shift
ENSG00000268713ENST00000600047exon_skip_380242chr3:186784961-186785101-12.74-0.1011EIF4A2ENST00000323963Frame-shift
ENSG00000268713ENST00000600047exon_skip_5818chr1:45568484-45568684-18.04-0.1037AKR1A1ENST00000351829,ENST00000372070Frame-shift
ENSG00000268713ENST00000600047exon_skip_11029chr1:154989559-154989707-14.37-0.1140FLAD1ENST00000292180Frame-shift
ENSG00000268713ENST00000600047exon_skip_41813chr10:68337857-68337996-14.60-0.1150HNRNPH3ENST00000265866Frame-shift
ENSG00000268713ENST00000600047exon_skip_74009chr11:64773429-64773505-12.18-0.1933SF1ENST00000377390Frame-shift
ENSG00000268713ENST00000600047exon_skip_309204chr19:49181348-49181461-14.25-0.1284TRPM4ENST00000252826Frame-shift
ENSG00000268713ENST00000600047exon_skip_319223chr19:43526200-43526349-17.22-0.1257ETHE1ENST00000292147Frame-shift
ENSG00000268713ENST00000600047exon_skip_382458chr3:38131595-38131638-7.48-0.2579ACAA1ENST00000333167Frame-shift
ENSG00000268713ENST00000600047exon_skip_9446chr1:147270931-147271005-9.51-0.2570CHD1LENST00000369258Frame-shift
ENSG00000268713ENST00000600047exon_skip_53559chr10:101793912-101793998-12.52-0.1987OGAENST00000361464Frame-shift
ENSG00000268713ENST00000600047exon_skip_66482chr11:126274926-126275021-12.93-0.1658FOXRED1ENST00000263578Frame-shift
ENSG00000268713ENST00000600047exon_skip_87733chr12:120571190-120571291-11.09-0.1848RNF10ENST00000325954Frame-shift
ENSG00000268713ENST00000600047exon_skip_90780chr12:26979783-26979936-12.57-0.1074TM7SF3ENST00000343028In-frame
ENSG00000268713ENST00000600047exon_skip_92074chr12:50142052-50142110-8.03-0.1709CERS5ENST00000317551Frame-shift
ENSG00000268713ENST00000600047exon_skip_114376chr14:74293153-74293248-9.98-0.1263ABCD4ENST00000356924Frame-shift
ENSG00000268713ENST00000600047exon_skip_128982chr15:72250844-72250954-13.73-0.1260PARP6ENST00000287196,ENST00000569795Frame-shift
ENSG00000268713ENST00000600047exon_skip_290158chr17:42953723-42953778-6.73-0.1869AARSD1ENST00000427569Frame-shift
ENSG00000268713ENST00000600047exon_skip_300663chr19:1425877-1425960-11.92-0.2091DAZAP1ENST00000233078Frame-shift
ENSG00000268713ENST00000600047exon_skip_302168chr19:10680345-10680443-9.46-0.1051ILF3ENST00000590261Frame-shift
ENSG00000268713ENST00000600047exon_skip_324294chr2:27774423-27774530-10.68-0.1271MRPL33ENST00000296102Frame-shift
ENSG00000268713ENST00000600047exon_skip_353131chr20:58669290-58669453-17.47-0.1444STX16ENST00000371141Frame-shift
ENSG00000268713ENST00000600047exon_skip_374497chr3:49999439-49999513-8.72-0.1896RBM6ENST00000266022Frame-shift
ENSG00000268713ENST00000600047exon_skip_377198chr3:123130479-123130616-12.12-0.1018PDIA5ENST00000316218Frame-shift
ENSG00000268713ENST00000600047exon_skip_430434chr4:82356536-82356683-9.81-0.1078HNRNPDENST00000313899In-frame
ENSG00000268713ENST00000600047exon_skip_462160chr6:127316449-127316502-7.88-0.1642ECHDC1ENST00000531967Frame-shift
ENSG00000268713ENST00000600047exon_skip_476549chr7:76013741-76013887-14.27-0.1151STYXL1ENST00000248600,ENST00000359697,ENST00000431581Frame-shift
ENSG00000268713ENST00000600047exon_skip_481699chr8:19824802-19824972-14.30-0.1075INTS10ENST00000397977Frame-shift
ENSG00000268713ENST00000600047exon_skip_509943chrX:47175018-47175092-11.70-0.2167RBM10ENST00000377604Frame-shift
ENSG00000268713ENST00000600047exon_skip_332658chr2:203272669-203272748-8.21-0.1173CYP20A1ENST00000356079Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for CTC-444N24.8

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types
ENSG00000268713ENSG00000179886TIGD5ENSG00000180035ZNF486CHOL,HNSC,KICH,KIRP,LIHC,MESO
ENSG00000268713ENSG00000105127AKAP8ENSG00000099326MZF15CHOL,GBM,KIRP,LGG,LIHC
ENSG00000268713ENSG00000130254SAFB2ENSG00000099326MZF111ACC,CHOL,ESCA,GBM,HNSC,KIRP,LGG,LIHC,LUAD,PAAD,PCPG
ENSG00000268713ENSG00000172273HINFPENSG00000099326MZF15CHOL,KIRC,KIRP,LIHC,PAAD
ENSG00000268713ENSG00000186272ZNF17ENSG00000099326MZF111ACC,CHOL,ESCA,GBM,LGG,LUAD,LUSC,OV,PAAD,SKCM,STAD
ENSG00000268713ENSG00000198040ZNF84ENSG00000099326MZF18BLCA,CHOL,ESCA,HNSC,KIRP,LIHC,LUAD,SKCM
ENSG00000268713ENSG00000278129ZNF8ENSG00000099326MZF18ESCA,GBM,LGG,LUAD,LUSC,MESO,PAAD,SKCM
ENSG00000268713ENSG00000105127AKAP8ENSG00000063244U2AF25ACC,CHOL,GBM,LGG,LIHC
ENSG00000268713ENSG00000130254SAFB2ENSG00000063244U2AF26ACC,CHOL,GBM,LGG,LIHC,PAAD
ENSG00000268713ENSG00000186272ZNF17ENSG00000063244U2AF25ACC,CHOL,GBM,LGG,PAAD
ENSG00000268713ENSG00000105127AKAP8ENSG00000167766ZNF836ACC,CHOL,GBM,KIRP,LGG,LIHC
ENSG00000268713ENSG00000130254SAFB2ENSG00000167766ZNF837CHOL,KIRP,LGG,LIHC,PAAD,PCPG,TGCT
ENSG00000268713ENSG00000172273HINFPENSG00000167766ZNF835CHOL,KIRC,KIRP,LIHC,PAAD
ENSG00000268713ENSG00000186272ZNF17ENSG00000167766ZNF8313ACC,BLCA,BRCA,CHOL,COAD,ESCA,GBM,LAML,LGG,LUAD,OV,SKCM,STAD
ENSG00000268713ENSG00000196670ZFP62ENSG00000167766ZNF835CHOL,COAD,LAML,READ,SKCM
ENSG00000268713ENSG00000196867ZFP28ENSG00000167766ZNF835GBM,LAML,LUAD,OV,TGCT
ENSG00000268713ENSG00000198040ZNF84ENSG00000167766ZNF8312BLCA,CHOL,COAD,ESCA,HNSC,KIRP,LAML,LIHC,LUAD,READ,SKCM,STAD
ENSG00000268713ENSG00000256223ZNF10ENSG00000167766ZNF838BLCA,ESCA,KIRP,LAML,LUAD,SKCM,TGCT,UCEC
ENSG00000268713ENSG00000278129ZNF8ENSG00000167766ZNF837COAD,GBM,LAML,LGG,LUAD,PAAD,SKCM
ENSG00000268713ENSG00000130254SAFB2ENSG00000126254RBM427ACC,CHOL,GBM,LGG,LIHC,PAAD,THCA
ENSG00000268713ENSG00000179886TIGD5ENSG00000126254RBM426CHOL,HNSC,KICH,KIRP,LIHC,MESO
ENSG00000268713ENSG00000105127AKAP8ENSG00000004534RBM65CHOL,GBM,KIRP,LGG,LIHC
ENSG00000268713ENSG00000130254SAFB2ENSG00000004534RBM612CHOL,ESCA,GBM,HNSC,KIRP,LGG,LIHC,LUAD,PAAD,PCPG,READ,TGCT
ENSG00000268713ENSG00000172273HINFPENSG00000004534RBM65CHOL,KIRC,KIRP,LIHC,PAAD
ENSG00000268713ENSG00000186272ZNF17ENSG00000004534RBM69CHOL,COAD,ESCA,GBM,LAML,LUAD,PAAD,SKCM,STAD
ENSG00000268713ENSG00000198040ZNF84ENSG00000004534RBM612BLCA,CHOL,COAD,ESCA,HNSC,KIRP,LAML,LIHC,LUAD,READ,SKCM,STAD
ENSG00000268713ENSG00000256223ZNF10ENSG00000004534RBM68BLCA,ESCA,KIRP,LAML,LUAD,SKCM,TGCT,UCEC
ENSG00000268713ENSG00000278129ZNF8ENSG00000004534RBM68COAD,ESCA,GBM,LGG,LUAD,LUSC,PAAD,SKCM
ENSG00000268713ENSG00000130254SAFB2ENSG00000105717PBX45CHOL,KIRP,LUAD,TGCT,THYM
ENSG00000268713ENSG00000172273HINFPENSG00000041988THAP35CHOL,KIRC,KIRP,LIHC,PAAD
ENSG00000268713ENSG00000179886TIGD5ENSG00000041988THAP35CHOL,HNSC,KIRP,LIHC,MESO
ENSG00000268713ENSG00000105127AKAP8ENSG00000099622CIRBP5ACC,CHOL,GBM,KIRP,LIHC
ENSG00000268713ENSG00000130254SAFB2ENSG00000099622CIRBP7ACC,CHOL,GBM,HNSC,KIRP,LIHC,THCA

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA-RBP complex negative regulation
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type
ENSG00000268713ENSG00000004534RBM6exon_skip_382458ENSG00000060971:chr3:38131595-38131638ACAA1ENST00000333167Frame-shiftSTAD,UVM,SKCM,READ,PCPG,PAAD,TGCT
ENSG00000268713ENSG00000079134THOC1exon_skip_382458ENSG00000060971:chr3:38131595-38131638ACAA1ENST00000333167Frame-shiftSTAD,UVM,SKCM,READ,THYM,PCPG,PAAD,TGCT,THCA
ENSG00000268713ENSG00000164548TRA2Aexon_skip_382458ENSG00000060971:chr3:38131595-38131638ACAA1ENST00000333167Frame-shiftSTAD,UVM,READ,THYM,PCPG,PAAD,TGCT,THCA

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000268713.1ENST00000600047.161560745