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lncRNA: ENSG00000268471

Summary for MIR4453HG

Gene summary

Gene information	Ensembl ID	ENSG00000268471
	Gene symbol	MIR4453HG
	Gene name	MIR4453 host gene
	HGNC	25288
	Entrez ID	54553
	Gene type	lincRNA
	Synonyms	MIR4453HG\|DKFZP434I0714\|04q31.3
	UniProtAcc

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Structure and expression level for MIR4453HG

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000268471	3.314459e+02	1.285914e+00	3.201490e-01	4.016610e+00	5.900000e-05	3.116150e-04	UP	GBM

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000268471	-3.250043e-01	2.168236e-15	THCA	4.419865e-14

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lncRNA-Protein interaction for MIR4453HG

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000118058	KMT2A	57.42	97.1356	Q03164	TF,Epi	ChIP-seq
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000104885	DOT1L	39.42	90.0027	Q8TEK3	TF,Epi	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000187605	TET3	37.91	93.2917	O43151	TF,Epi	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000010803	SCMH1	35.19	90.7198	Q96GD3	TF,Epi	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000123636	BAZ2B	68.22	96.5881	Q9UIF8	TF,Epi	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000025293	PHF20	60.25	92.7053	Q9BVI0	TF,Epi	ChIP-seq
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000084093	REST	42.85	95.717	Q13127	TF,Epi	ChIP-seq
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000076108	BAZ2A	41.28	94.4954	Q9UIF9	TF,RBP,Epi	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000168769	TET2	38.01	96.2016	Q6N021	TF,Epi	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000198176	TFDP1	19.19	91.9735	Q14186	TF,Epi	ChIP-seq

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000125812	GZF1	77.32	93.9753	Q9H116	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000123636	BAZ2B	68.22	96.6107	Q9UIF8	TF,Epi	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000140836	ZFHX3	67.45	96.5999	Q15911	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000102189	EEA1	66.19	95.0818	Q15075	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000144747	TMF1	66.06	96.0132	P82094	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000174282	ZBTB4	61.22	92.2614	Q9P1Z0	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000025293	PHF20	60.25	92.8339	Q9BVI0	TF,Epi	ChIP-seq
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000118058	KMT2A	57.42	97.1896	Q03164	TF,Epi	ChIP-seq
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000096401	CDC5L	57.01	93.9643	Q99459	TF,RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000198300	PEG3	54.51	93.5751	Q9GZU2	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000164916	FOXK1	53.14	93.6902	P85037	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000105127	AKAP8	52.71	95.1728	O43823	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000124459	ZNF45	49.8	93.1839	Q02386	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000276644	DACH1	49.36	93.1528	Q9UI36	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000126804	ZBTB1	48.86	95.5104	Q9Y2K1	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000146587	RBAK	48.7	94.2832	Q9NYW8	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000100207	TCF20	48.56	96.0927	Q9UGU0	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000198538	ZNF28	47.66	94.908	P17035	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000198455	ZXDB	47.06	90.838	P98169	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000196867	ZFP28	45.89	93.0966	Q8NHY6	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000084093	REST	42.85	96.213	Q13127	TF,Epi	ChIP-seq
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000169635	HIC2	42.43	94.286	Q96JB3	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000167232	ZNF91	42.34	96.0512	Q05481	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000156273	BACH1	41.76	94.1418	O14867	TF	ChIP-seq
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000076108	BAZ2A	41.28	94.6325	Q9UIF9	TF,RBP,Epi	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000198815	FOXJ3	41.08	94.4799	Q9UPW0	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000147124	ZNF41	40.91	92.6975	P51814	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000104885	DOT1L	39.42	90.0909	Q8TEK3	TF,Epi	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000136451	VEZF1	39.03	91.6164	Q14119	TF	ChIP-seq
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000168769	TET2	38.01	96.3081	Q6N021	TF,Epi	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000147789	ZNF7	37.98	94.2512	P17097	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000187605	TET3	37.91	93.4242	O43151	TF,Epi	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000164631	ZNF12	37.66	92.9644	P17014	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000142065	ZFP14	37.44	92.7676	Q9HCL3	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000171649	ZIK1	37.43	92.806	Q3SY52	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000198521	ZNF43	35.48	95.6278	P17038	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000010803	SCMH1	35.19	90.9363	Q96GD3	TF,Epi	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000181007	ZFP82	35.16	93.2234	Q8N141	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000120784	ZFP30	34.92	93.6607	Q9Y2G7	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000197857	ZNF44	33.52	95.2317	P15621	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000117000	RLF	32.97	96.1172	Q13129	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000184939	ZFP90	32.45	92.0412	Q8TF47	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000065029	ZNF76	32.0	93.5536	P36508	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000174738	NR1D2	31.99	92.1684	Q14995	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000168795	ZBTB5	31.81	91.584	O15062	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000198040	ZNF84	30.67	94.6559	P51523	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000196233	LCOR	30.41	90.1658	Q96JN0	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000168661	ZNF30	28.0	93.0037	P17039	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000198429	ZNF69	26.95	91.8113	Q9UC07	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000105708	ZNF14	26.72	91.1538	P17017	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000181472	ZBTB2	25.24	92.2119	Q8N680	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000184635	ZNF93	25.18	93.9912	P35789	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000186660	ZFP91	24.74	92.6006	Q96JP5	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000184517	ZFP1	24.47	90.5715	Q6P2D0	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000175691	ZNF77	24.47	91.8087	Q15935	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000166526	ZNF3	24.46	92.026	P17036	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000256223	ZNF10	23.37	93.696	P21506	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000120690	ELF1	20.99	92.1289	P32519	TF	ChIP-seq
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000198176	TFDP1	19.19	92.8614	Q14186	TF,Epi	ChIP-seq
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000187792	ZNF70	18.72	94.3524	Q9UC06	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000187815	ZFP69	18.65	92.929	Q49AA0	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000136936	XPA	18.4	90.1343	P23025	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000196378	ZNF34	16.26	95.5926	Q8IZ26	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000062194	GPBP1	16.24	93.3538	Q86WP2	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000204304	PBX2	15.0	90.7053	P40425	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000105750	ZNF85	13.12	94.9557	Q03923	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000119138	KLF9	12.85	91.2041	Q13886	TF	ChIP-seq
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000144161	ZC3H8	11.36	93.411	Q8N5P1	TF,RBP	ChIP-seq
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000146757	ZNF92	11.09	94.2685	Q03936	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000196152	ZNF79	11.03	92.0652	Q15937	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000114126	TFDP2	10.79	92.8924	Q14188	TF	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000175395	ZNF25	9.52	92.7394	P17030	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000056097	ZFR	63.37	96.6481	Q96KR1	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000096401	CDC5L	57.01	93.9695	Q99459	TF,RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000100650	SRSF5	55.22	93.9041	Q13243	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000137776	SLTM	54.29	97.383	Q9NWH9	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000124193	SRSF6	48.89	95.5662	Q13247	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000004534	RBM6	47.67	93.5497	P78332	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000198000	NOL8	45.22	95.3553	Q76FK4	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000099622	CIRBP	43.72	90.644	Q14011	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000076108	BAZ2A	41.28	94.6339	Q9UIF9	TF,RBP,Epi	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000162775	RBM15	40.13	93.032	Q96T37	RBP	eCLIP
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000106344	RBM28	40.01	95.3705	Q9NW13	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000089280	FUS	39.5	91.0517	P35637	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000161813	LARP4	38.84	93.2967	Q71RC2	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000145907	G3BP1	37.32	93.1488	Q13283	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000135870	RC3H1	34.89	94.4015	Q5TC82	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000121390	PSPC1	30.06	95.7365	Q8WXF1	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000133226	SRRM1	28.87	96.8642	Q8IYB3	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000108349	CASC3	27.36	94.1003	O15234	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000147274	RBMX	24.39	93.1506	P38159	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000167978	SRRM2	16.3	97.385	Q9UQ35	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000124214	STAU1	12.91	93.142	O95793	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000161547	SRSF2	11.51	93.2027	Q01130	RBP	NA
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000144161	ZC3H8	11.36	93.324	Q8N5P1	TF,RBP	ChIP-seq
ENSG00000268471	ENST00000604157	DKFZP434I0714	ENSG00000107164	FUBP3	7.03	92.0233	Q96I24	RBP	NA

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lncRNA-DNA interaction for MIR4453HG

lncRNA targets the enhancer region and positively regulates the gene expression.

Only predicted by TDF

ZNF30,CEBPZ,RBM19,NCOA2,DNMT1,PUM1,XRN1,KLF9,ILF3,CPEB2,PBX2,RBM39,EDC3,KLF12,ZBTB4,GLYR1,KLF7,CIRBP,LCORL,MZF1,MYSM1,NRF1,RBM23,RFX5,AKAP8,ZNF2,KAT7,ARID2,ZXDC,SUGP2,DMTF1,ELF1,VEZF1,RBM27,ZNF70,BAZ2A,ZNF77,ZNF24,DDX52,RORA,RBM28,ATF6B,ZNF74,TBP,GABPA,IKZF5,ZBED4,DDX55,KMT2B,TET3,ZBTB5,ZFP14,ZXDA,RNPC3,ZFP69,BARD1,TRPS1,KDM5B,NOP9,ATMIN,THOC1,ZNF25,MNT,TRNT1,LARP7,PNPT1,CNOT4,SON,CHTOP,CWC22,DDX59,ZZZ3,ZBED5,SCAF4,TTC14,ZBED3,RBM4,MEX3C,CREB1,RC3H1,HIF1A,EEA1,ZNF44,ZFP91,ZNF91,RBMX,AGO2,RBM4B,U2AF2,CSTF3,TIGD6,RBM26,ZFP1,ZIK1,RBM14,PURB,GZF1,ADNP,NCBP1,MYEF2,PPIL4,TERF2,MBD1,IKZF4,PUS7L,ASH1L,CLOCK,NFIA,CASC3,FUBP1,RBM15,ARNT2,ZFP30,SP4,RBM43,CPSF7,KLF11,PRDM4,TCF20,LIN54,UBR5,THAP9,THOC2,DDX6,TSN,ZBTB6,ZNF34,THAP6,PATZ1,DDX17,ZBTB2,E2F5,SRRM2,RFX7,E2F6,PRR12,AQR,ZNF22,SP2,FMR1,LCOR,ZHX3,MECP2,FOXJ3,KLF3,PURA,PHAX,ZNF41,ZC3H8,TTF1,RBM41,SART3,THAP1,DZIP3,SRBD1,ZFP82,ZFP62,MEX3D,SGSM2,ZNF93,SMAD3,PAIP1,WIZ,ZNF28,ZNF45,CELF1,SCMH1,PSPC1,KRR1,TMF1,TIGD1,ELK4,RBM45,NFXL1,PRDM2,BACH1,DDX51,RBM18,UNC50,SRSF2,MBD6,DDX31,SALL2,MYNN,TFCP2,ZMAT1,ZNF83,SKIL,QKI,ZFR,NSUN6,ZNF3,RFX3,NXF1,STAU1,ZFX,ZNF8,NAF1,NKRF,NR2C2,EIF2D,SYNJ1,PUS10,GPBP1,SOX12,ARNT,KDM2B,RBM6,ZNF14,RBM48,G3BP2,LSM11,GMEB2,ZFHX3,PUM2,XPO1,RBM5,CPEB3,ELF2,SMAD4,TIGD2,RBMS1,NFYB,IKZF2,ZNF43,PTBP3,ZFP28,MTF1,SP3,ZNF17,SRCAP,DOT1L,ZNF84,DDX42,BAZ2B,RXRB,ZHX2,TRA2A,KMT2A,ZNF69,SRSF7,HINFP,XPA,NR2C1,TFDP2,DACH1,ZFP3,MECOM,ADAT1,ZBED6,SFPQ,ETV3,TET2,TDRKH,RBM33,NOL8,ATF2,ZNF10

Exist in public source

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for MIR4453HG

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

TEAD4,RNH1

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000268471	ENST00000604157	exon_skip_150854	chr17:32366664-32366757	-11.01	-0.1237	ZNF207	ENST00000321233	In-frame
ENSG00000268471	ENST00000604157	exon_skip_430633	chr4:82861630-82861708	-11.18	-0.1620	SEC31A	ENST00000355196,ENST00000395310,ENST00000448323	In-frame

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000268471	ENST00000604157	exon_skip_111863	chr14:23565815-23565892	-14.39	-0.2822	AP1G2	ENST00000308724,ENST00000397120	Frame-shift
ENSG00000268471	ENST00000604157	exon_skip_133217	chr16:8635038-8635079	-11.43	-0.4970	METTL22	ENST00000381920	Frame-shift
ENSG00000268471	ENST00000604157	exon_skip_290158	chr17:42953723-42953778	-9.09	-4.5450	AARSD1	ENST00000427569	Frame-shift
ENSG00000268471	ENST00000604157	exon_skip_382458	chr3:38131595-38131638	-9.34	-0.2278	ACAA1	ENST00000333167	Frame-shift
ENSG00000268471	ENST00000604157	exon_skip_326885	chr2:74490024-74490127	-20.61	-0.2513	TTC31	ENST00000233623	Frame-shift
ENSG00000268471	ENST00000604157	exon_skip_83419	chr12:53467804-53467843	-11.68	-0.2995	PCBP2	ENST00000439930	In-frame

lncRNA targets by miRNA.

LncRNA Ensembl ID	miRNA ID	LncRNA ENST ID	Binding site in lncRNA	Score	Energy	Align Len	Public source
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152537929-152538012	199.00	-70.54	80	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152536666-152536759	186.00	-73.48	86	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152536415-152536505	184.00	-95.19	90	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152538047-152538132	182.00	-77.85	78	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152537018-152537110	180.00	-71.58	87	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152538129-152538207	175.00	-66.95	84	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152538873-152538960	170.00	-61.28	79	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152536864-152536949	166.00	-72.78	84	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152536305-152536394	163.00	-84.77	82	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152538219-152538298	163.00	-72.01	82	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152538793-152538883	163.00	-65.54	84	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152538317-152538397	160.00	-69.05	87	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152538985-152539072	160.00	-73.97	84	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152537499-152537591	159.00	-74.15	85	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152537231-152537313	153.00	-61.36	75	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152537684-152537778	144.00	-68.44	83	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152536784-152536866	141.00	-71.05	83	NA
ENSG00000268471	hsa-mir-22	ENST00000604157	chr4:152539159-152539243	141.00	-62.25	75	NA

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Variants for MIR4453HG

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID	RBP ID	RBP Gene Name	Exon Skipping ID	Skipped Exon	EX Gene Name	EX Affected TransID	ORF_anno	Cancer Type
ENSG00000268471	ENSG00000004534	RBM6	exon_skip_382458	ENSG00000060971:chr3:38131595-38131638	ACAA1	ENST00000333167	Frame-shift	SKCM,READ,UCS,PAAD,TGCT
ENSG00000268471	ENSG00000124193	SRSF6	exon_skip_382458	ENSG00000060971:chr3:38131595-38131638	ACAA1	ENST00000333167	Frame-shift	SKCM,READ,UCS,PAAD,TGCT

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID	lncRNA-miRNA-mRNA	Cancer Types
ENSG00000268471	MIR4453HG,hsa-mir-22,WDR33	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,ZHX2	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,PHF2	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,KAT7	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,COIL	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,TRMT10B	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,USP21	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,YTHDC1	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,CCDC66	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,RPRD2	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,INO80D	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,KANSL1	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,NAA16	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,ERCC3	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,RBM4B	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,COA5	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,RAD52	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,PCF11	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,NAB1	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,ING5	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,CLK2	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,KHDC4	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,CEP95	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,EIF4ENIF1	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,TIA1	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,DPF2	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,MSL1	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,RC3H1	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,RBBP6	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,EDRF1	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,RBMX	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,PMS1	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,UBE2G2	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,FBXO46	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,PHF12	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,MSL2	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,RCOR3	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,ANGEL2	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,RBM14	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,UIMC1	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,SF3B1	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,FNBP4	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,SRSF1	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,DGCR8	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,POGZ	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,CTDSPL2	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,BUD13	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,CASC3	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,N4BP2L2	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,PRPF39	KICH,LGG,DLBC,SARC,KIRP
ENSG00000268471	MIR4453HG,hsa-mir-22,KATNBL1	KICH,LGG,DLBC,SARC,KIRP

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000268471.4	ENST00000604157.1	63	188	0

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential