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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000267530

Summary for LINC01836

check button Gene summary

Gene informationEnsembl ID

ENSG00000267530

Gene symbol

LINC01836

Gene namelong intergenic non-protein coding RNA 1836
HGNC

52652

Entrez ID

107985343

Gene typelincRNA
SynonymsAC006273.5|LINC01836|19p13.3
UniProtAcc

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Structure and expression level for LINC01836

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002675302.305647e+023.397432e+005.119995e-016.635615e+003.230000e-114.560000e-10UPCHOL
ENSG000002675301.391399e+02-3.121724e+003.911911e-01-7.980049e+001.460000e-151.550000e-14DOWNKICH
ENSG000002675301.069706e+02-1.197915e+002.480446e-01-4.829435e+001.370000e-065.830000e-06DOWNKIRP
ENSG000002675306.113614e+01-1.645969e+001.793513e-01-9.177342e+004.420000e-204.510000e-19DOWNLUAD
ENSG000002675305.468613e+011.856661e+002.671517e-016.949840e+003.660000e-126.620000e-11UPSTAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002675303.611507e-011.479377e-02CHOL1.661090e-02
ENSG00000267530-5.831392e-012.017614e-09KICH1.439112e-08
ENSG00000267530-3.172681e-013.602887e-15LUAD5.154308e-14

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lncRNA-Protein interaction for LINC01836

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000267530ENST00000606242AC006273.5ENSG00000099326MZF148.0493.1429P28698TFChIP-seq
ENSG00000267530ENST00000606242AC006273.5ENSG00000197857ZNF4413.2992.8844P15621TFNA
ENSG00000267530ENST00000606242AC006273.5ENSG00000275410HNF1B10.6390.4014P35680TFNA
ENSG00000267530ENST00000606242AC006273.5ENSG00000198429ZNF699.2391.5333Q9UC07TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000267530ENST00000606242AC006273.5ENSG00000100650SRSF525.3390.1292Q13243RBPNA

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lncRNA-DNA interaction for LINC01836

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
RXRB,CIRBP,OVOL2,ZNF44,MZF1,HES1,GATA6,RNPC3,UNC50,FOXJ1,IRX3,ZNF69,CENPT,HNF1B
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for LINC01836

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for LINC01836

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name
LncEditing_340814ENSG00000267530.2chr19784313+lincRNAAC006273.5ENST00000606242.1lincRNAAC006273.5-002
LncEditing_340854ENSG00000267530.2chr19784404+lincRNAAC006273.5ENST00000606242.1lincRNAAC006273.5-002
LncEditing_340859ENSG00000267530.2chr19784999+lincRNAAC006273.5ENST00000586061.1lincRNAAC006273.5-001
LncEditing_340860ENSG00000267530.2chr19785000+lincRNAAC006273.5ENST00000586061.1lincRNAAC006273.5-001
LncEditing_340861ENSG00000267530.2chr19785002+lincRNAAC006273.5ENST00000586061.1lincRNAAC006273.5-001
LncEditing_340870ENSG00000267530.2chr19785068+lincRNAAC006273.5ENST00000586061.1lincRNAAC006273.5-001

check buttonEdited-associated DElncRNAs in cancer.
Differentially expressed gene
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange
ENSG00000267530LncEditing_340860KIRCchr19_785000_+5.038950e+002.427174e+009.489054e-017.997565e+001.269041e-152.461874e-15UP
ENSG00000267530LncEditing_340860MESOchr19_785000_+5.496803e+003.716753e+001.771323e+002.779261e+005.448268e-036.896073e-03UP
ENSG00000267530LncEditing_340814CHOLchr19_784313_+1.681325e+018.017314e+009.359719e-012.164478e+003.042766e-023.453951e-02UP
ENSG00000267530LncEditing_340854CHOLchr19_784404_+1.792118e+017.878823e+008.434453e-012.466499e+001.364413e-021.933261e-02UP
ENSG00000267530LncEditing_340861CHOLchr19_785002_+1.122699e+016.997278e+001.466050e+002.392409e+001.673817e-022.237676e-02UP
ENSG00000267530LncEditing_340861OVchr19_785002_+4.128402e+001.934847e+009.146084e-017.761263e+008.408756e-152.290919e-14UP
ENSG00000267530LncEditing_340859PAADchr19_784999_+3.278342e+001.447918e+008.481858e-016.625619e+003.457953e-112.112495e-10UP
ENSG00000267530LncEditing_340861PAADchr19_785002_+3.530244e+001.670901e+009.266621e-015.061955e+004.149795e-079.113276e-07UP

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value
ENSG00000267530LncEditing_340861-3.269774e-011.798189e-021.980747e-02
ENSG00000267530LncEditing_340859-9.780336e-013.895265e-031.655488e-02
ENSG00000267530LncEditing_340859-5.984341e-019.759108e-045.313292e-03
ENSG00000267530LncEditing_340861-8.429969e-012.955591e-042.068914e-03
ENSG00000267530LncEditing_340859-5.802916e-016.981362e-052.521051e-03
ENSG00000267530LncEditing_340860-7.728634e-013.204758e-031.098774e-02
ENSG00000267530LncEditing_340861-5.888503e-011.639909e-022.802038e-02
ENSG00000267530LncEditing_340870-7.248857e-012.713842e-023.715665e-02
ENSG00000267530LncEditing_340859-3.215179e-013.786823e-024.192554e-02
ENSG00000267530LncEditing_340861-3.781910e-011.760219e-022.153952e-02
ENSG00000267530LncEditing_340859-5.256935e-013.764892e-054.455122e-04

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000267530.2ENST00000606242.1113787446
ENSG00000267530.2ENST00000586061.1142700272