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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000267493

Summary for CIRBP-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000267493

Gene symbol

CIRBP-AS1

Gene nameCIRBP antisense RNA 1
HGNC

28588

Entrez ID

148046

Gene typeantisense
SynonymsCIRBP-AS1|19p13.3
UniProtAcc

Q8TBR5


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Structure and expression level for CIRBP-AS1

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002674939.445293e+012.020579e+005.135943e-013.934192e+008.350000e-051.045188e-03UPCESC
ENSG000002674934.227777e+011.153112e+001.548051e-017.448801e+009.420000e-148.800000e-13UPUCEC
ENSG000002674938.805092e+011.191332e+001.151716e-011.034397e+014.460000e-252.170000e-23UPPRAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002674933.901063e-018.069608e-03CHOL9.750776e-03
ENSG000002674933.911099e-011.393283e-21PRAD4.560681e-20

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lncRNA-Protein interaction for CIRBP-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000275023MLLT622.1790.8242P55198EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000108557RAI121.594.2442Q7Z5J4EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000132382MYBBP1A21.4791.0743Q9BQG0EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000165288BRWD321.0895.4245Q6RI45EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000160949TONSL19.9992.1821Q96HA7EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000103549RNF4019.9493.4188O75150EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000196498NCOR219.6394.9692Q9Y618EpiChIP-seq
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000108799EZH117.2290.4217Q92800EpiChIP-seq
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000106462EZH216.5892.453Q15910EpiChIP-seq
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000183495EP40015.5996.1246Q96L91EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000137337MDC115.5394.2743Q14676EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000120071KANSL111.9393.5769Q7Z3B3EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000171456ASXL111.5793.3631Q8IXJ9EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000168137SETD524.9994.0605Q9C0A6EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000132780NASP24.1793.5672P49321EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000141867BRD422.6493.6363O60885EpiChIP-seq
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000181090EHMT122.3791.4376Q9H9B1EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000167670CHAF1A22.3393.2458Q13111EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000001497LAS1L18.4590.3131Q9Y4W2EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000104885DOT1L17.8993.5282Q8TEK3TF,EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000171634BPTF17.4795.9892Q12830TF,EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000154832CXXC115.9990.8943Q9P0U4TF,EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000167548KMT2D15.9795.9561O14686EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000272333KMT2B13.0694.1131Q9UMN6TF,EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000130254SAFB222.2993.7461Q14151TF,RBPNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000105127AKAP820.2192.4956O43823TFNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000011451WIZ18.1392.008O95785TFNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000104885DOT1L17.8993.3803Q8TEK3TF,EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000171634BPTF17.4795.6439Q12830TF,EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000272333KMT2B13.0694.276Q9UMN6TF,EpiNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000198040ZNF8412.1791.2425P51523TFChIP-seq

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000004534RBM622.4793.4224P78332RBPNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000130254SAFB222.2994.1585Q14151TF,RBPNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000198000NOL820.1293.0242Q76FK4RBPNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000106344RBM2819.7292.0944Q9NW13RBPNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000137776SLTM18.8494.4512Q9NWH9RBPENCODE
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000089280FUS15.0391.6084P35637RBPHigh-throughput data combine LncPro prediction
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000135870RC3H113.6591.6468Q5TC82RBPNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000133226SRRM110.9494.9947Q8IYB3RBPNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000129351ILF310.8690.9442Q12906RBPNA
ENSG00000267493ENST00000585832CIRBP-AS1ENSG00000167978SRRM26.3694.7598Q9UQ35RBPNA

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lncRNA-DNA interaction for CIRBP-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for CIRBP-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000267493ENST00000585832exon_skip_293617chr17:76091142-76091235-13.04-0.2006EXOC7ENST00000589210In-frame

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for CIRBP-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000267493.3ENST00000585832.225577841