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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000266036

Summary for SLC9A3R1-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000266036

Gene symbol

SLC9A3R1-AS1

Gene nameSLC9A3R1 antisense RNA 1
HGNC

55322

Entrez ID
Gene typeantisense
SynonymsRP11-452I5.2|17q25.1|SLC9A3R1-AS1
UniProtAcc

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Structure and expression level for SLC9A3R1-AS1

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002660363.078392e+01-1.510742e+003.958259e-01-3.816684e+001.352570e-046.466350e-04DOWNGBM
ENSG000002660361.905606e+023.954332e+007.346846e-015.382353e+007.350000e-082.560000e-06UPCESC
ENSG000002660361.259986e+022.588518e+001.789019e-011.446892e+011.900000e-474.210000e-46UPLUSC
ENSG000002660362.273344e+021.727741e+001.440013e-011.199809e+013.640000e-334.190000e-32UPBRCA
ENSG000002660365.679762e+01-2.221423e+001.788415e-01-1.242119e+012.010000e-357.460000e-34DOWNCOAD
ENSG000002660362.239769e+02-1.227196e+002.033050e-01-6.036230e+001.580000e-091.790000e-08DOWNSTAD
ENSG000002660364.688305e+01-1.250741e+003.017526e-01-4.144923e+003.400000e-052.910740e-04DOWNREAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value

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lncRNA-Protein interaction for SLC9A3R1-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for SLC9A3R1-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for SLC9A3R1-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
UBL5,PPP2R3C,PCGF1,RPL35,CHKB,RRAS,NXT1,CSNK2B,ELOC,ARL6IP4,LUC7L,C19orf53,PFDN5,ELK3,TRAPPC2B,PRAF2,PPP1R35,DDX39A,UCHL3,TRIR,TIMM9,RPP30,LUC7L3,RHOJ,MIER2,SCNM1,KATNBL1,PFDN6,VKORC1,PFDN2,NDUFV2,RANGRF,RPL35A,NDUFB8,LGALS1,PFDN4,ILKAP
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000266036ENST00000585285exon_skip_37475chr1:225504990-225505053-7.19-0.1383ENAHENST00000366844In-frame
ENSG00000266036ENST00000585285exon_skip_44998chr10:110132304-110132400-11.13-0.1464ADD3ENST00000356080In-frame
ENSG00000266036ENST00000585285exon_skip_384879chr3:52554723-52554879-25.57-0.1739PBRM1ENST00000296302In-frame
ENSG00000266036ENST00000585285exon_skip_423795chr4:55888887-55888932-9.43-0.2858EXOC1ENST00000346134,ENST00000381295In-frame
ENSG00000266036ENST00000585285exon_skip_461111chr6:90544551-90544632-13.01-0.1971MAP3K7ENST00000369329In-frame
ENSG00000266036ENST00000585285exon_skip_499771chr9:128592982-128593042-14.16-0.2529SPTAN1ENST00000372731In-frame
ENSG00000266036ENST00000585285exon_skip_111863chr14:23565815-23565892-14.49-0.2013AP1G2ENST00000308724,ENST00000397120Frame-shift
ENSG00000266036ENST00000585285exon_skip_324294chr2:27774423-27774530-12.80-0.4741MRPL33ENST00000296102Frame-shift
ENSG00000266036ENST00000585285exon_skip_353131chr20:58669290-58669453-32.38-0.2103STX16ENST00000371141Frame-shift
ENSG00000266036ENST00000585285exon_skip_382458chr3:38131595-38131638-10.23-0.2436ACAA1ENST00000333167Frame-shift
ENSG00000266036ENST00000585285exon_skip_434332chr5:34813573-34813660-11.33-0.1531RAI14ENST00000265109,ENST00000428746,ENST00000503673In-frame
ENSG00000266036ENST00000585285exon_skip_53559chr10:101793912-101793998-13.37-0.2057OGAENST00000361464Frame-shift
ENSG00000266036ENST00000585285exon_skip_326741chr2:73946718-73946906-20.82-0.1176DGUOKENST00000264093Frame-shift
ENSG00000266036ENST00000585285exon_skip_67074chr11:406842-406993-28.52-0.2052SIGIRRENST00000332725,ENST00000397632,ENST00000431843Frame-shift
ENSG00000266036ENST00000585285exon_skip_386291chr3:108050577-108050602-5.34-0.7629CD47ENST00000361309Frame-shift
ENSG00000266036ENST00000585285exon_skip_516535chrX:119840645-119840684-5.86-0.2930UPF3BENST00000276201In-frame
ENSG00000266036ENST00000585285exon_skip_5818chr1:45568484-45568684-21.50-0.1201AKR1A1ENST00000351829,ENST00000372070Frame-shift
ENSG00000266036ENST00000585285exon_skip_140339chr16:635611-635774-27.18-0.1999METTL26ENST00000301686Frame-shift
ENSG00000266036ENST00000585285exon_skip_52891chr10:98429790-98429889-23.09-0.2537HPS1ENST00000325103,ENST00000361490In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000266036ENST00000585285exon_skip_361434chr21:25997359-25997416-12.93-0.5622APPENST00000346798In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for SLC9A3R1-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000266036ENST00000585285LUC7LENSG00000007392ENST00000426094-0.109613READ-
ENSG00000266036ENST00000585285LUC7LENSG00000007392ENST00000397783-0.102157READ-
ENSG00000266036ENST00000585285LUC7LENSG00000007392ENST00000429378-0.1034162READ-
ENSG00000266036ENST00000585285LUC7LENSG00000007392ENST00000442701-0.16183READ-
ENSG00000266036ENST00000585285LUC7LENSG00000007392ENST00000397780-0.225818READ-
ENSG00000266036ENST00000585285PFDN5ENSG00000123349ENST00000551018-0.1926112GBMCESC
ENSG00000266036ENST00000585285PFDN5ENSG00000123349ENST00000351500-0.1926112GBMCESC
ENSG00000266036ENST00000585285PFDN5ENSG00000123349ENST00000550846-0.1926112GBMCESC
ENSG00000266036ENST00000585285PFDN5ENSG00000123349ENST00000243040-0.1045131GBMCESC
ENSG00000266036ENST00000585285PFDN5ENSG00000123349ENST00000334478-0.1926112GBMCESC
ENSG00000266036ENST00000585285PFDN5ENSG00000123349ENST00000549759-0.201969GBMCESC
ENSG00000266036ENST00000585285RPL35AENSG00000182899ENST00000448864-0.1141202GBM-
ENSG00000266036ENST00000585285RPL35AENSG00000182899ENST00000429437-0.100111GBM-
ENSG00000266036ENST00000585285NXT1ENSG00000132661ENST00000254998-0.1058393GBM,COAD,READ-
ENSG00000266036ENST00000585285RPL35ENSG00000136942ENST00000373570-0.16811GBM-
ENSG00000266036ENST00000585285RPL35ENSG00000136942ENST00000493018-0.10261GBM-
ENSG00000266036ENST00000585285RPL35ENSG00000136942ENST00000348462-0.2738304GBM-
ENSG00000266036ENST00000585285UBL5ENSG00000198258ENST00000586895-0.2046245GBM-
ENSG00000266036ENST00000585285UBL5ENSG00000198258ENST00000358666-0.1500244GBM-
ENSG00000266036ENST00000585285UBL5ENSG00000198258ENST00000590068-0.1500244GBM-
ENSG00000266036ENST00000585285UBL5ENSG00000198258ENST00000593087-0.1101246GBM-
ENSG00000266036ENST00000585285RRASENSG00000126458ENST00000246792-0.11601GBMCESC,LUSC
ENSG00000266036ENST00000585285RHOJENSG00000126785ENST00000316754-0.13651GBMCESC,LUSC,BRCA

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000266036.1ENST00000585285.193391110