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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000265743

Summary for RP11-848P1.3

check button Gene summary

Gene informationEnsembl ID

ENSG00000265743

Gene symbol

RP11-848P1.3

Gene name
HGNC
Entrez ID
Gene typelincRNA
Synonyms
UniProtAcc

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Structure and expression level for RP11-848P1.3

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002657438.183345e+011.511062e+004.283905e-013.527301e+004.198200e-041.757128e-03UPGBM
ENSG000002657431.037265e+022.427247e+001.052651e-012.305842e+011.210000e-1173.110000e-115UPKIRC
ENSG000002657433.050153e+011.224191e+002.762035e-014.432205e+009.330000e-063.130000e-05UPKICH
ENSG000002657437.348993e+011.742424e+001.939352e-018.984567e+002.600000e-195.810000e-18UPKIRP

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002657433.721325e-012.091728e-21KIRC2.091728e-20

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lncRNA-Protein interaction for RP11-848P1.3

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000265743ENST00000579561RP11-848P1.3ENSG00000169554ZEB249.0893.4144O60315TFNA
ENSG00000265743ENST00000579561RP11-848P1.3ENSG00000114861FOXP149.0790.0663Q9H334TF,EpiNA
ENSG00000265743ENST00000579561RP11-848P1.3ENSG00000071655MBD33.3590.7438O95983TF,EpiNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for RP11-848P1.3

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
AKNA,ELF4,SLIRP,ISG20,RNH1,CEBPA,JDP2,SP140,FOXP3,HLX,NR1H3,TLR8,HIC1,STAT4,IRF3,BATF3,EGR2,SP100,IRF2,ETV7,JAZF1,RBMS1,IMP3,PHF19,SNAI3,TFEB,KLF2,RUNX3,ETS1,MBD3,AHR,ZEB2,CENPB,FOXP1,RUNX1,MAFB,NFKB1,GLMP,MAF,MEF2C,BCL6B,STAT2,IKZF3,TEP1,MBD2,FLI1,DHX58,IRF7,HEYL,TFEC,USF1,SP110,QKI,IRF1,TFE3,SPI1,ZNF18,MOV10,BATF2,STAT1,CREM,STAT6
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.
Only predicted by TDF
TFEC,RUNX3,GLMP,CENPB,ZNF18,MBNL1,PHF19,STAT2,KLF2,STAT4,IKZF3,HIC1,TEP1,ETV7,FOXS1,FLI1
Exist in public source
NA

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.
Only predicted by TDF
GTF2I,ZFR,SF3A1,ADNP,PPIL4,AKAP1
Exist in public source
NA

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lncRNA-RNA interaction for RP11-848P1.3

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
ILF3,AKAP1,RBMX,SF3A1,TSN,KAT7
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000265743ENST00000579561exon_skip_75398chr11:72692752-72692785-8.33-4.1650ARAP1ENST00000393605In-frame
ENSG00000265743ENST00000579561exon_skip_33516chr1:156938417-156938513-8.86-0.1737ARHGEF11ENST00000361409In-frame
ENSG00000265743ENST00000579561exon_skip_96112chr12:109945259-109945349-9.84-0.1158GIT2ENST00000355312In-frame
ENSG00000265743ENST00000579561exon_skip_368285chr22:29329711-29329720-2.79-1.3950AP1B1ENST00000357586,ENST00000405198In-frame
ENSG00000265743ENST00000579561exon_skip_382356chr3:37091466-37091538-7.50-0.1293LRRFIP2ENST00000336686In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000265743ENST00000579561exon_skip_434332chr5:34813573-34813660-9.76-0.1375RAI14ENST00000265109,ENST00000428746,ENST00000503673In-frame
ENSG00000265743ENST00000579561exon_skip_482403chr8:27445793-27445919-10.66-0.2600PTK2BENST00000346049,ENST00000397501In-frame
ENSG00000265743ENST00000579561exon_skip_484062chr8:73030335-73030395-6.91-0.1382TERF1ENST00000276603In-frame
ENSG00000265743ENST00000579561exon_skip_48713chr10:34336198-34336243-5.42-0.2853PARD3ENST00000374789In-frame
ENSG00000265743ENST00000579561exon_skip_146683chr16:85780378-85780473-9.89-0.1301EMC8ENST00000253457Frame-shift
ENSG00000265743ENST00000579561exon_skip_378912chr3:152446703-152446757-5.51-0.1777MBNL1ENST00000282486,ENST00000463374In-frame
ENSG00000265743ENST00000579561exon_skip_423795chr4:55888887-55888932-7.04-0.2347EXOC1ENST00000346134,ENST00000381295In-frame
ENSG00000265743ENST00000579561exon_skip_456460chr6:17771113-17771218-9.61-0.1045KIF13AENST00000259711In-frame
ENSG00000265743ENST00000579561exon_skip_499771chr9:128592982-128593042-7.13-0.1620SPTAN1ENST00000372731In-frame
ENSG00000265743ENST00000579561exon_skip_13507chr1:162592731-162592782-6.00-0.1765UAP1ENST00000271469,ENST00000367925In-frame
ENSG00000265743ENST00000579561exon_skip_462673chr6:138926400-138926481-7.77-0.1126REPS1ENST00000450536In-frame
ENSG00000265743ENST00000579561exon_skip_379903chr3:184180644-184180650-2.01-0.4020AP2M1ENST00000292807In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RP11-848P1.3

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types
ENSG00000265743ENSG00000169554ZEB2ENSG00000152601MBNL15COAD,KIRC,PAAD,STAD,TGCT
ENSG00000265743ENSG00000169554ZEB2ENSG00000170581STAT25COAD,ESCA,KIRC,PAAD,STAD
ENSG00000265743ENSG00000169554ZEB2ENSG00000161405IKZF35COAD,KIRC,LUAD,PAAD,THCA
ENSG00000265743ENSG00000169554ZEB2ENSG00000177374HIC16BRCA,ESCA,LUSC,PAAD,STAD,TGCT
ENSG00000265743ENSG00000114861FOXP1ENSG00000151702FLI15ACC,COAD,LUSC,PCPG,SKCM
ENSG00000265743ENSG00000169554ZEB2ENSG00000151702FLI111BLCA,BRCA,COAD,ESCA,KIRC,LUSC,PAAD,PCPG,STAD,TGCT,THCA

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000265743.1ENST00000579561.1110195527