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lncRNA: ENSG00000264577

Summary for AC010761.8

Gene summary

Gene information	Ensembl ID	ENSG00000264577
	Gene symbol	AC010761.8
	Gene name
	HGNC
	Entrez ID
	Gene type	antisense
	Synonyms
	UniProtAcc

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Structure and expression level for AC010761.8

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000264577	5.277015e+01	1.289980e+00	3.168248e-01	4.071587e+00	4.670000e-05	2.195890e-04	UP	CHOL
ENSG00000264577	4.707376e+01	1.155402e+00	1.797265e-01	6.428668e+00	1.290000e-10	1.020000e-09	UP	KIRP
ENSG00000264577	6.705854e+01	1.284366e+00	1.373289e-01	9.352481e+00	8.560000e-21	1.210000e-19	UP	COAD
ENSG00000264577	6.144831e+01	1.203276e+00	2.511454e-01	4.791153e+00	1.660000e-06	1.990000e-05	UP	READ

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000264577	5.358519e-01	1.485432e-04	CHOL	4.095897e-04
ENSG00000264577	3.183598e-01	1.916585e-14	PRAD	1.263146e-13

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lncRNA-Protein interaction for AC010761.8

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000264577	ENST00000582718	AC010761.8	ENSG00000185658	BRWD1	55.4	91.8644	Q9NSI6	Epi	NA
ENSG00000264577	ENST00000582718	AC010761.8	ENSG00000171634	BPTF	45.14	92.2478	Q12830	TF,Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000264577	ENST00000582718	AC010761.8	ENSG00000130254	SAFB2	57.57	93.1194	Q14151	TF,RBP	ENCODE
ENSG00000264577	ENST00000582718	AC010761.8	ENSG00000171634	BPTF	45.14	92.1467	Q12830	TF,Epi	NA
ENSG00000264577	ENST00000582718	AC010761.8	ENSG00000117000	RLF	37.92	90.8985	Q13129	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000264577	ENST00000582718	AC010761.8	ENSG00000198231	DDX42	60.51	90.5777	Q86XP3	RBP	NA
ENSG00000264577	ENST00000582718	AC010761.8	ENSG00000130254	SAFB2	57.57	93.2681	Q14151	TF,RBP	ENCODE
ENSG00000264577	ENST00000582718	AC010761.8	ENSG00000004534	RBM6	57.27	91.6621	P78332	RBP	NA
ENSG00000264577	ENST00000582718	AC010761.8	ENSG00000198000	NOL8	53.13	91.7262	Q76FK4	RBP	NA
ENSG00000264577	ENST00000582718	AC010761.8	ENSG00000137776	SLTM	49.8	93.6532	Q9NWH9	RBP	NA
ENSG00000264577	ENST00000582718	AC010761.8	ENSG00000133226	SRRM1	23.89	90.9726	Q8IYB3	RBP	NA
ENSG00000264577	ENST00000582718	AC010761.8	ENSG00000167978	SRRM2	17.22	95.1431	Q9UQ35	RBP	NA

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lncRNA-DNA interaction for AC010761.8

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for AC010761.8

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

RNH1,CPQ,SMPD1,ATP6V0D1,MYH9,PRKACA,ILK,TMEM127,ZFYVE1,SPRYD3,TMBIM1,TOLLIP,NFIX,TNS1,LRP10,PLD3,CRAT,CYB5R3,BTD,EVI5L,DCAF11,ATP6V0C,IL17RC,OS9,GABARAP,MYO1C,ILRUN

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000264577	ENST00000582718	exon_skip_462673	chr6:138926400-138926481	-11.94	-0.2487	REPS1	ENST00000450536	In-frame
ENSG00000264577	ENST00000582718	exon_skip_1234	chr1:11658532-11658628	-15.35	-0.1725	FBXO44	ENST00000251547,ENST00000376770	In-frame
ENSG00000264577	ENST00000582718	exon_skip_287762	chr17:28884224-28884315	-12.21	-0.1471	FLOT2	ENST00000394908	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_470077	chr7:102397619-102397698	-9.80	-0.2178	PRKRIP1	ENST00000397912,ENST00000496391	Frame-shift

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000264577	ENST00000582718	exon_skip_11029	chr1:154989559-154989707	-18.19	-0.1467	FLAD1	ENST00000292180	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_77641	chr11:117207066-117207160	-11.34	-0.2314	PCSK7	ENST00000320934	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_110809	chr14:105449358-105449409	-15.28	-0.6367	MTA1	ENST00000331320	In-frame
ENSG00000264577	ENST00000582718	exon_skip_123601	chr15:74897010-74897219	-17.72	-0.2685	MPI	ENST00000352410	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_309204	chr19:49181348-49181461	-19.80	-0.2475	TRPM4	ENST00000252826	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_353131	chr20:58669290-58669453	-25.71	-0.1785	STX16	ENST00000371141	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_374552	chr3:50104247-50104308	-7.33	-0.1437	RBM5	ENST00000347869	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_377198	chr3:123130479-123130616	-16.29	-0.1293	PDIA5	ENST00000316218	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_380242	chr3:186784961-186785101	-14.37	-0.1369	EIF4A2	ENST00000323963	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_382458	chr3:38131595-38131638	-7.40	-0.2056	ACAA1	ENST00000333167	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_446758	chr5:178212972-178213103	-15.65	-0.1252	PHYKPL	ENST00000308158	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_446770	chr5:178215275-178215430	-20.33	-0.1422	PHYKPL	ENST00000308158	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_2106	chr1:17648553-17648675	-14.88	-0.1378	ARHGEF10L	ENST00000361221	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_9446	chr1:147270931-147271005	-9.72	-0.2627	CHD1L	ENST00000369258	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_41813	chr10:68337857-68337996	-16.15	-0.1223	HNRNPH3	ENST00000265866	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_52891	chr10:98429790-98429889	-17.95	-0.2017	HPS1	ENST00000325103,ENST00000361490	In-frame
ENSG00000264577	ENST00000582718	exon_skip_53559	chr10:101793912-101793998	-12.04	-0.1416	OGA	ENST00000361464	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_95407	chr12:95040475-95040597	-13.16	-0.1106	NR2C1	ENST00000333003	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_114365	chr14:74290026-74290118	-14.57	-0.2857	ABCD4	ENST00000356924	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_133217	chr16:8635038-8635079	-10.58	-0.7053	METTL22	ENST00000381920	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_138351	chr16:70469151-70469323	-23.71	-0.1560	FUK	ENST00000288078	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_290158	chr17:42953723-42953778	-6.49	-0.1411	AARSD1	ENST00000427569	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_364741	chr22:31603743-31603819	-12.95	-0.1727	SFI1	ENST00000400288	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_370518	chr22:50247691-50247776	-14.79	-0.3018	HDAC10	ENST00000216271	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_374497	chr3:49999439-49999513	-9.31	-0.1552	RBM6	ENST00000266022	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_438188	chr5:141638954-141639021	-11.19	-0.1998	RELL2	ENST00000297164,ENST00000444782	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_444499	chr5:138164086-138164133	-7.18	-0.1710	BRD8	ENST00000254900	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_445390	chr5:150403120-150403312	-20.89	-0.1180	CD74	ENST00000009530	In-frame
ENSG00000264577	ENST00000582718	exon_skip_470226	chr7:103307595-103307708	-13.74	-0.1598	PMPCB	ENST00000249269	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_511212	chrX:71555189-71555385	-17.79	-0.1218	OGT	ENST00000373719	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_1717	chr1:15721328-15721388	-9.03	-0.1505	PLEKHM2	ENST00000375799	In-frame
ENSG00000264577	ENST00000582718	exon_skip_93979	chr12:57107604-57107743	-16.12	-0.1194	STAT6	ENST00000300134,ENST00000454075,ENST00000543873,ENST00000556155	Frame-shift
ENSG00000264577	ENST00000582718	exon_skip_340759	chr2:85552415-85552567	-14.55	-0.1347	GGCX	ENST00000233838	Frame-shift

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for AC010761.8

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID	RBP ID	RBP Gene Name	Exon Skipping ID	Skipped Exon	EX Gene Name	EX Affected TransID	ORF_anno	Cancer Type
ENSG00000264577	ENSG00000004534	RBM6	exon_skip_382458	ENSG00000060971:chr3:38131595-38131638	ACAA1	ENST00000333167	Frame-shift	STAD,UVM,SKCM,READ,MESO,THYM,PAAD
ENSG00000264577	ENSG00000004534	RBM6	exon_skip_370518	ENSG00000100429:chr22:50247691-50247776	HDAC10	ENST00000216271	Frame-shift	UVM,SKCM,READ,PRAD,PAAD
ENSG00000264577	ENSG00000004534	RBM6	exon_skip_444499	ENSG00000112983:chr5:138164086-138164133	BRD8	ENST00000254900	Frame-shift	UVM,SKCM,READ,THYM,PAAD

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID	LncRNA ENST ID	PC Gene Name	PC Gene ID	PC ENST ID	dG	nDG	Cancer with PC gene up-regulation	Cancer with PC gene Down-regulation
ENSG00000264577	ENST00000582718	TOLLIP	ENSG00000078902	ENST00000527938	-0.1281	286	-	CHOL
ENSG00000264577	ENST00000582718	CRAT	ENSG00000095321	ENST00000455396	-0.1241	378	-	CHOL,COAD
ENSG00000264577	ENST00000582718	DCAF11	ENSG00000100897	ENST00000560457	-0.1343	411	-	CHOL
ENSG00000264577	ENST00000582718	DCAF11	ENSG00000100897	ENST00000558706	-0.1277	391	-	CHOL
ENSG00000264577	ENST00000582718	DCAF11	ENSG00000100897	ENST00000560614	-0.1151	149	-	CHOL
ENSG00000264577	ENST00000582718	DCAF11	ENSG00000100897	ENST00000557888	-0.1315	396	-	CHOL
ENSG00000264577	ENST00000582718	DCAF11	ENSG00000100897	ENST00000559451	-0.1151	167	-	CHOL
ENSG00000264577	ENST00000582718	DCAF11	ENSG00000100897	ENST00000559144	-0.1179	65	-	CHOL
ENSG00000264577	ENST00000582718	IL17RC	ENSG00000163702	ENST00000383812	-0.2517	712	-	CHOL
ENSG00000264577	ENST00000582718	IL17RC	ENSG00000163702	ENST00000416074	-0.3047	267	-	CHOL
ENSG00000264577	ENST00000582718	IL17RC	ENSG00000163702	ENST00000295981	-0.3047	267	-	CHOL
ENSG00000264577	ENST00000582718	IL17RC	ENSG00000163702	ENST00000403601	-0.2522	114	-	CHOL
ENSG00000264577	ENST00000582718	IL17RC	ENSG00000163702	ENST00000455057	-0.2517	712	-	CHOL
ENSG00000264577	ENST00000582718	IL17RC	ENSG00000163702	ENST00000413608	-0.2517	713	-	CHOL
ENSG00000264577	ENST00000582718	BTD	ENSG00000169814	ENST00000449107	-0.1617	429	-	CHOL,COAD
ENSG00000264577	ENST00000582718	BTD	ENSG00000169814	ENST00000437172	-0.1088	296	-	CHOL,COAD
ENSG00000264577	ENST00000582718	SMPD1	ENSG00000166311	ENST00000527275	-0.1464	387	-	CHOL,COAD,READ
ENSG00000264577	ENST00000582718	GABARAP	ENSG00000170296	ENST00000573928	-0.2004	486	-	COAD,READ
ENSG00000264577	ENST00000582718	TNS1	ENSG00000079308	ENST00000453356	-0.1220	149	-	KIRP,COAD,READ
ENSG00000264577	ENST00000582718	CPQ	ENSG00000104324	ENST00000522617	-0.2313	132	-	COAD,READ
ENSG00000264577	ENST00000582718	ILK	ENSG00000166333	ENST00000532063	-0.1074	279	-	COAD,READ
ENSG00000264577	ENST00000582718	ILK	ENSG00000166333	ENST00000537806	-0.1093	318	-	COAD,READ
ENSG00000264577	ENST00000582718	ILK	ENSG00000166333	ENST00000420936	-0.1093	320	-	COAD,READ
ENSG00000264577	ENST00000582718	ILK	ENSG00000166333	ENST00000528995	-0.1057	287	-	COAD,READ
ENSG00000264577	ENST00000582718	ILK	ENSG00000166333	ENST00000526318	-0.1029	282	-	COAD,READ

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000264577.1	ENST00000582718.1	57	219	392

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential