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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000262468

Summary for LINC01569

check button Gene summary

Gene informationEnsembl ID

ENSG00000262468

Gene symbol

LINC01569

Gene namelong intergenic non-protein coding RNA 1569
HGNC

51380

Entrez ID
Gene typelincRNA
SynonymsLINC01569|16p13.3
UniProtAcc

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Structure and expression level for LINC01569

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002624684.791402e+021.444617e+001.850951e-017.804732e+005.960000e-158.240000e-14UPKIRP
ENSG000002624681.590773e+021.213487e+001.174921e-011.032825e+015.250000e-254.420000e-24UPLUSC
ENSG000002624682.452073e+021.123597e+008.964432e-021.253395e+014.870000e-366.280000e-35UPBRCA
ENSG000002624681.560961e+021.474587e+001.309130e-011.126387e+011.980000e-293.770000e-28UPLUAD
ENSG000002624681.078333e+021.316159e+001.351590e-019.737857e+002.080000e-223.280000e-21UPCOAD
ENSG000002624681.232981e+021.606389e+002.652371e-016.056427e+001.390000e-093.450000e-08UPREAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value

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lncRNA-Protein interaction for LINC01569

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000262468ENST00000573042LINC01569ENSG00000140632GLYR117.6791.2057Q49A26TF,EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000262468ENST00000573268LINC01569ENSG00000167967E4F168.5791.2209Q66K89TFNA
ENSG00000262468ENST00000573042LINC01569ENSG00000130254SAFB237.3993.6838Q14151TF,RBPNA
ENSG00000262468ENST00000573042LINC01569ENSG00000167967E4F136.293.1618Q66K89TFNA
ENSG00000262468ENST00000573042LINC01569ENSG00000099326MZF130.2991.4367P28698TFChIP-seq
ENSG00000262468ENST00000573042LINC01569ENSG00000147789ZNF725.3592.2795P17097TFNA
ENSG00000262468ENST00000573042LINC01569ENSG00000140632GLYR117.6790.7043Q49A26TF,EpiNA
ENSG00000262468ENST00000573042LINC01569ENSG00000177732SOX1213.690.3507O15370TFNA
ENSG00000262468ENST00000573042LINC01569ENSG00000167766ZNF8310.8191.4736P51522TFChIP-seq
ENSG00000262468ENST00000573042LINC01569ENSG00000105717PBX44.8790.0941Q9BYU1TFNA
ENSG00000262468ENST00000573268LINC01569ENSG00000154957ZNF183.9990.5293P17022TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000262468ENST00000573042LINC01569ENSG00000130254SAFB237.3993.53Q14151TF,RBPNA
ENSG00000262468ENST00000573042LINC01569ENSG00000004534RBM635.7393.7088P78332RBPNA
ENSG00000262468ENST00000573268LINC01569ENSG00000160917CPSF425.9490.9384O95639RBPNA
ENSG00000262468ENST00000573042LINC01569ENSG00000150316CWC1517.5290.5638Q9P013RBPNA
ENSG00000262468ENST00000573268LINC01569ENSG00000278619MRM113.3191.674Q6IN84RBPNA

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lncRNA-DNA interaction for LINC01569

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
HSF1,TFAP4,SOX12,PHF1,SLIRP,TBX6,GLI4,CENPT,NOL3,HSF4,GLYR1,THOC6,IRF3,CIRBP,MRM1,SUGP1,DDX56,IMP3,THAP8,TIGD5,MZF1,PARN,DMTF1,TIGD6,TIGD1,CPSF1,RNPS1,DDX51,RPP25,THAP3,CWC15,NFYC,DHX34,HINFP,CPSF4,PPIE,PBX4,ZMAT1,ZNF83,DHX58,RALY,NSUN6,SNRPA,NXF1,SAFB2,THOC1,ZNF18
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.
Only predicted by TDF
HSF4,MZF1,NOL3,ZNF18,E4F1,ZMAT1,RNPS1,TFAP4,RBM6,PBX4,THAP3,CIRBP
Exist in public source
NA

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for LINC01569

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
SMAD1,ATF1,UHMK1,QKI,REST,CSDE1
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000262468ENST00000573268exon_skip_48713chr10:34336198-34336243-10.19-0.2754PARD3ENST00000374789In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000262468ENST00000573268exon_skip_445633chr5:151110626-151110644-7.29-0.8100ANXA6ENST00000354546In-frame
ENSG00000262468ENST00000573268exon_skip_446770chr5:178215275-178215430-16.63-0.1526PHYKPLENST00000308158Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for LINC01569

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types
ENSG00000262468ENSG00000147789ZNF7ENSG00000102878HSF45CHOL,KIRC,LGG,LUSC,MESO
ENSG00000262468ENSG00000167967E4F1ENSG00000102878HSF413BLCA,BRCA,CHOL,COAD,GBM,KIRC,KIRP,LGG,LUAD,LUSC,PAAD,PRAD,SKCM
ENSG00000262468ENSG00000154957ZNF18ENSG00000102878HSF47CHOL,GBM,KIRC,KIRP,PRAD,THCA,THYM
ENSG00000262468ENSG00000167967E4F1ENSG00000140939NOL37COAD,KIRC,KIRP,LGG,LUAD,PAAD,SARC
ENSG00000262468ENSG00000130254SAFB2ENSG00000167967E4F15CHOL,KIRC,KIRP,LGG,TGCT
ENSG00000262468ENSG00000147789ZNF7ENSG00000167967E4F15CHOL,KIRC,LGG,LUSC,PRAD
ENSG00000262468ENSG00000147789ZNF7ENSG00000205937RNPS15CHOL,KIRC,LGG,LUSC,PRAD
ENSG00000262468ENSG00000167967E4F1ENSG00000205937RNPS113BRCA,CHOL,COAD,GBM,KIRC,KIRP,LGG,LIHC,LUAD,LUSC,PAAD,PRAD,SARC
ENSG00000262468ENSG00000147789ZNF7ENSG00000090447TFAP45CHOL,KIRC,LGG,LUSC,PRAD
ENSG00000262468ENSG00000167967E4F1ENSG00000090447TFAP49BRCA,CHOL,COAD,KIRC,LGG,LUAD,LUSC,PAAD,PRAD
ENSG00000262468ENSG00000167967E4F1ENSG00000004534RBM65CHOL,KIRP,LGG,PRAD,TGCT
ENSG00000262468ENSG00000167967E4F1ENSG00000041988THAP36BRCA,CHOL,KIRC,LIHC,LUAD,SKCM

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000262468.4ENST00000573042.19725315
ENSG00000262468.4ENST00000571970.49213151037
ENSG00000262468.4ENST00000573268.195524237