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lncRNA: ENSG00000261512

Summary for RP11-46D6.1

Gene summary

Gene information	Ensembl ID	ENSG00000261512
	Gene symbol	RP11-46D6.1
	Gene name
	HGNC
	Entrez ID
	Gene type	lincRNA
	Synonyms
	UniProtAcc

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Structure and expression level for RP11-46D6.1

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID

Base mean

log2FC(AD/control)

lfcSE

Stat

P-value

Adjc.p-value

DEG direction

Cancer type

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000261512	3.331625e-01	2.532890e-02	CHOL	2.686204e-02

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lncRNA-Protein interaction for RP11-46D6.1

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000261512	ENST00000562549	RP11-46D6.1	ENSG00000104885	DOT1L	81.03	93.2831	Q8TEK3	TF,Epi	NA
ENSG00000261512	ENST00000562549	RP11-46D6.1	ENSG00000140632	GLYR1	17.43	92.9993	Q49A26	TF,Epi	NA
ENSG00000261512	ENST00000562549	RP11-46D6.1	ENSG00000117139	KDM5B	100.74	92.8466	Q9UGL1	TF,Epi	NA
ENSG00000261512	ENST00000562549	RP11-46D6.1	ENSG00000173120	KDM2A	74.5	93.3095	Q9Y2K7	TF,Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000261512	ENST00000574180	RP11-46D6.1	ENSG00000117139	KDM5B	88.58	94.7444	Q9UGL1	TF,Epi	NA
ENSG00000261512	ENST00000574180	RP11-46D6.1	ENSG00000104885	DOT1L	75.13	95.6388	Q8TEK3	TF,Epi	NA
ENSG00000261512	ENST00000574180	RP11-46D6.1	ENSG00000173120	KDM2A	71.6	93.9937	Q9Y2K7	TF,Epi	NA
ENSG00000261512	ENST00000574180	RP11-46D6.1	ENSG00000140632	GLYR1	18.58	92.9723	Q49A26	TF,Epi	NA
ENSG00000261512	ENST00000562549	RP11-46D6.1	ENSG00000117139	KDM5B	100.74	92.3078	Q9UGL1	TF,Epi	NA
ENSG00000261512	ENST00000562549	RP11-46D6.1	ENSG00000104885	DOT1L	81.03	93.4137	Q8TEK3	TF,Epi	NA
ENSG00000261512	ENST00000562549	RP11-46D6.1	ENSG00000173120	KDM2A	74.5	92.7475	Q9Y2K7	TF,Epi	NA
ENSG00000261512	ENST00000562549	RP11-46D6.1	ENSG00000140632	GLYR1	17.43	93.7042	Q49A26	TF,Epi	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000261512	ENST00000574180	RP11-46D6.1	ENSG00000132153	DHX30	59.21	93.7895	Q7L2E3	RBP	NA

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lncRNA-DNA interaction for RP11-46D6.1

lncRNA targets the enhancer region and positively regulates the gene expression.

Only predicted by TDF

PRR12,SP2,RFX1,GLYR1,ETV5,MTF1,SRCAP,DOT1L,WIZ,ZXDC,MAZ,MBD4,BAZ2A,HELZ2,NACC2,ZBED4,KMT2B,MEF2D,TCF20,ELK1,STAU1,KDM5B,NOP9,ZBTB2,MNT

Exist in public source

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-46D6.1

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000261512	ENST00000574180	exon_skip_430434	chr4:82356536-82356683	-17.50	-0.1562	HNRNPD	ENST00000313899	In-frame

-lncRNA and exonskipping events are negatively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

LOF

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for RP11-46D6.1

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000261512.2	ENST00000562549.2	116	495	145
ENSG00000261512.2	ENST00000574180.1	218	0	656

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential