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lncRNA: ENSG00000261188

Summary for TFIP11-DT

Gene summary

Gene information	Ensembl ID	ENSG00000261188
	Gene symbol	TFIP11-DT
	Gene name	TFIP11 divergent transcript
	HGNC	55374
	Entrez ID
	Gene type	antisense
	Synonyms	CTA-445C9.14\|22q12.1\|TFIP11-DT
	UniProtAcc

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Structure and expression level for TFIP11-DT

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000261188	1.512539e+02	1.271433e+00	3.037272e-01	4.186102e+00	2.840000e-05	1.400840e-04	UP	CHOL
ENSG00000261188	2.300777e+02	1.050785e+00	1.274003e-01	8.247902e+00	1.610000e-16	8.620000e-16	UP	LUSC

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000261188	5.431081e-01	1.157755e-04	CHOL	3.345952e-04

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lncRNA-Protein interaction for TFIP11-DT

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000132780	NASP	80.35	94.7997	P49321	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000001497	LAS1L	57.33	91.9744	Q9Y4W2	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000120616	EPC1	46.96	92.0047	Q9H2F5	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000117625	RCOR3	24.86	93.0466	Q9P2K3	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000105821	DNAJC2	18.71	92.3869	Q99543	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000280789	PAGR1	8.07	90.8937	Q9BTK6	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000025293	PHF20	90.86	90.9322	Q9BVI0	TF,Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000155827	RNF20	83.35	93.9352	Q5VTR2	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000145241	CENPC	71.89	92.4089	Q03188	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000067334	DNTTIP2	70.76	92.3115	Q5QJE6	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000108799	EZH1	56.23	93.5578	Q92800	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000106462	EZH2	53.4	93.8698	Q15910	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000137337	MDC1	52.02	94.4055	Q14676	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000120071	KANSL1	37.18	91.831	Q7Z3B3	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000171456	ASXL1	34.4	94.1496	Q8IXJ9	Epi	NA
ENSG00000261188	ENST00000565764	CTA-445C9.14	ENSG00000171456	ASXL1	24.79	92.2926	Q8IXJ9	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000164985	PSIP1	14.76	92.4397	O75475	Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000149929	HIRIP3	12.78	94.712	Q9BW71	Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000025293	PHF20	90.86	90.8588	Q9BVI0	TF,Epi	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000167967	E4F1	75.11	94.2113	Q66K89	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000100207	TCF20	67.95	94.2005	Q9UGU0	TF	NA
ENSG00000261188	ENST00000565764	CTA-445C9.14	ENSG00000100207	TCF20	46.69	91.6188	Q9UGU0	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000125812	GZF1	46.36	94.3871	Q9H116	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000124459	ZNF45	42.87	93.4929	Q02386	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000147789	ZNF7	42.23	93.068	P17097	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000146587	RBAK	41.21	91.9275	Q9NYW8	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000198040	ZNF84	40.24	92.8292	P51523	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000170448	NFXL1	39.79	90.616	Q6ZNB6	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000168795	ZBTB5	34.48	94.8395	O15062	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000164631	ZNF12	29.33	91.0125	P17014	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000105708	ZNF14	23.85	90.3763	P17017	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000197857	ZNF44	21.75	92.4926	P15621	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000184939	ZFP90	20.53	90.0418	Q8TF47	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000142065	ZFP14	20.31	90.8141	Q9HCL3	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000065029	ZNF76	19.14	93.1487	P36508	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000169635	HIC2	18.72	93.4809	Q96JB3	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000166526	ZNF3	15.45	90.8459	P17036	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000256223	ZNF10	14.97	90.6706	P21506	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000109381	ELF2	14.26	90.226	Q15723	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000175691	ZNF77	12.69	90.6866	Q15935	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000187792	ZNF70	10.89	91.0555	Q9UC06	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000196378	ZNF34	9.45	94.2364	Q8IZ26	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000187815	ZFP69	9.37	90.7891	Q49AA0	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000278129	ZNF8	8.68	90.2165	P17098	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000146757	ZNF92	6.88	92.6197	Q03936	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000186130	ZBTB6	6.83	90.4496	Q15916	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000114126	TFDP2	5.55	91.1522	Q14188	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000175395	ZNF25	5.19	92.2684	P17030	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000275111	ZNF2	4.29	91.5388	Q9BSG1	TF	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000085274	MYNN	3.25	90.6193	Q9NPC7	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000198000	NOL8	64.86	94.2118	Q76FK4	RBP	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000106344	RBM28	63.92	94.8094	Q9NW13	RBP	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000137776	SLTM	62.7	95.7064	Q9NWH9	RBP	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000100650	SRSF5	33.17	90.3849	Q13243	RBP	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000124193	SRSF6	26.3	92.0874	Q13247	RBP	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000179151	EDC3	19.22	91.3838	Q96F86	RBP	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000204356	NELFE	17.06	93.5989	P18615	RBP	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000121390	PSPC1	17.06	91.4843	Q8WXF1	RBP	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000108349	CASC3	14.83	92.2239	O15234	RBP	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000174720	LARP7	14.52	90.3328	Q4G0J3	RBP	NA
ENSG00000261188	ENST00000566814	CTA-445C9.14	ENSG00000150316	CWC15	11.87	91.8143	Q9P013	RBP	NA

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lncRNA-DNA interaction for TFIP11-DT

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for TFIP11-DT

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

ITGB2,MOB3A,PML,RAB31,FAH,MYH9,LMNA,TNFRSF1A,TGFB1,S100A11,PLAUR,ACTN4,TMBIM1,RHOG,LRP10,IQGAP1,GALM,CAST,STAT6,EHD2,RIN3,SERPINA1,MKNK2,RNF19B,SLC9A1,CDKN1A,VASP,IFITM3,HK3,CAP1,VSIR,ALDH3B1,MYD88

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000261188	ENST00000565764	exon_skip_430601	chr4:82842139-82842481	-23.26	-0.1181	SEC31A	ENST00000355196,ENST00000395310,ENST00000448323	In-frame
ENSG00000261188	ENST00000565764	exon_skip_430633	chr4:82861630-82861708	-13.15	-0.1852	SEC31A	ENST00000355196,ENST00000395310,ENST00000448323	In-frame
ENSG00000261188	ENST00000565764	exon_skip_51046	chr10:73439871-73439901	-6.39	-1.5975	PPP3CB	ENST00000360663	In-frame

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000261188	ENST00000565764	exon_skip_81540	chr12:42384939-42384996	-10.82	-0.2459	PPHLN1	ENST00000395568	In-frame
ENSG00000261188	ENST00000565764	exon_skip_370518	chr22:50247691-50247776	-12.77	-0.1726	HDAC10	ENST00000216271	Frame-shift
ENSG00000261188	ENST00000565764	exon_skip_382458	chr3:38131595-38131638	-7.82	-0.3400	ACAA1	ENST00000333167	Frame-shift
ENSG00000261188	ENST00000565764	exon_skip_132355	chr16:1786756-1786955	-23.77	-0.1585	NUBP2	ENST00000262302	Frame-shift
ENSG00000261188	ENST00000565764	exon_skip_319223	chr19:43526200-43526349	-19.73	-0.1451	ETHE1	ENST00000292147	Frame-shift
ENSG00000261188	ENST00000565764	exon_skip_333962	chr2:219247112-219247246	-24.34	-0.1979	STK16	ENST00000396738,ENST00000409638	Frame-shift
ENSG00000261188	ENST00000565764	exon_skip_377198	chr3:123130479-123130616	-19.86	-0.1540	PDIA5	ENST00000316218	Frame-shift
ENSG00000261188	ENST00000565764	exon_skip_494079	chr8:144099080-144099205	-18.23	-0.1720	SHARPIN	ENST00000398712	Frame-shift
ENSG00000261188	ENST00000565764	exon_skip_436498	chr5:96729152-96729209	-6.67	-0.2900	CAST	ENST00000341926,ENST00000395813	In-frame

lncRNA targets by miRNA.

LncRNA Ensembl ID	miRNA ID	LncRNA ENST ID	Binding site in lncRNA	Score	Energy	Align Len	Public source
ENSG00000261188	hsa-mir-1228	ENST00000566814	chr22:26512588-26512667	173.00	-87.07	72	NA
ENSG00000261188	hsa-mir-1228	ENST00000566814	chr22:26513092-26513166	150.00	-70.67	71	NA
ENSG00000261188	hsa-mir-1228	ENST00000566814	chr22:26513701-26513773	147.00	-68.05	66	NA
ENSG00000261188	hsa-mir-1228	ENST00000566814	chr22:26514012-26514082	141.00	-64.40	68	NA
ENSG00000261188	hsa-mir-1228	ENST00000565764	chr22:26512588-26512667	173.00	-87.07	72	NA
ENSG00000261188	hsa-mir-1228	ENST00000565764	chr22:26513324-26513396	147.00	-68.05	66	NA

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Variants for TFIP11-DT

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID	LncRNA ENST ID	PC Gene Name	PC Gene ID	PC ENST ID	dG	nDG	Cancer with PC gene up-regulation	Cancer with PC gene Down-regulation
ENSG00000261188	ENST00000566814	FAH	ENSG00000103876	ENST00000261755	-0.1241	1421	-	CHOL
ENSG00000261188	ENST00000566814	FAH	ENSG00000103876	ENST00000561421	-0.1261	1162	-	CHOL
ENSG00000261188	ENST00000566814	FAH	ENSG00000103876	ENST00000539156	-0.1666	14	-	CHOL
ENSG00000261188	ENST00000566814	FAH	ENSG00000103876	ENST00000561353	-0.1424	34	-	CHOL
ENSG00000261188	ENST00000566814	GALM	ENSG00000143891	ENST00000434934	-0.2412	273	-	CHOL
ENSG00000261188	ENST00000566814	HK3	ENSG00000160883	ENST00000292432	-0.1178	1	-	CHOL,LUSC
ENSG00000261188	ENST00000566814	HK3	ENSG00000160883	ENST00000509717	-0.1259	1251	-	CHOL,LUSC
ENSG00000261188	ENST00000566814	MYD88	ENSG00000172936	ENST00000443433	-0.1647	1	-	CHOL
ENSG00000261188	ENST00000566814	SERPINA1	ENSG00000197249	ENST00000393087	-0.1537	88	-	CHOL,LUSC
ENSG00000261188	ENST00000566814	SERPINA1	ENSG00000197249	ENST00000393088	-0.1826	38	-	CHOL,LUSC
ENSG00000261188	ENST00000566814	SERPINA1	ENSG00000197249	ENST00000404814	-0.2387	270	-	CHOL,LUSC
ENSG00000261188	ENST00000565764	FAH	ENSG00000103876	ENST00000261755	-0.1295	44	-	CHOL
ENSG00000261188	ENST00000565764	FAH	ENSG00000103876	ENST00000561421	-0.1261	767	-	CHOL
ENSG00000261188	ENST00000565764	FAH	ENSG00000103876	ENST00000539156	-0.1310	39	-	CHOL
ENSG00000261188	ENST00000565764	FAH	ENSG00000103876	ENST00000561353	-0.1424	16	-	CHOL
ENSG00000261188	ENST00000565764	GALM	ENSG00000143891	ENST00000434934	-0.2412	255	-	CHOL
ENSG00000261188	ENST00000565764	HK3	ENSG00000160883	ENST00000292432	-0.1636	1	-	CHOL,LUSC
ENSG00000261188	ENST00000565764	HK3	ENSG00000160883	ENST00000509717	-0.1259	856	-	CHOL,LUSC
ENSG00000261188	ENST00000565764	MYD88	ENSG00000172936	ENST00000443433	-0.1672	1	-	CHOL
ENSG00000261188	ENST00000565764	SERPINA1	ENSG00000197249	ENST00000393087	-0.1537	70	-	CHOL,LUSC
ENSG00000261188	ENST00000565764	SERPINA1	ENSG00000197249	ENST00000393088	-0.1826	20	-	CHOL,LUSC
ENSG00000261188	ENST00000565764	SERPINA1	ENSG00000197249	ENST00000404814	-0.2387	252	-	CHOL,LUSC

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000261188.1	ENST00000566814.1	148	2313	2759
ENSG00000261188.1	ENST00000565764.1	85	1692	1435

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential