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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000260804

Summary for LINC01963

check button Gene summary

Gene informationEnsembl ID

ENSG00000260804

Gene symbol

LINC01963

Gene namelong intergenic non-protein coding RNA 1963
HGNC

25283

Entrez ID

150967

Gene typelincRNA
SynonymsPKI55|LINC01963|02q35
UniProtAcc

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Structure and expression level for LINC01963

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002608041.546884e+03-1.233627e+002.789194e-01-4.422881e+009.740000e-066.260000e-05DOWNGBM
ENSG000002608043.807303e+022.415931e+003.155903e-017.655276e+001.930000e-144.400000e-13UPCHOL
ENSG000002608041.050958e+031.667430e+003.407487e-014.893429e+009.910000e-073.500000e-05UPPCPG
ENSG000002608042.579644e+02-1.149258e+001.414759e-01-8.123348e+004.530000e-162.360000e-15DOWNLUSC
ENSG000002608042.364310e+02-1.218710e+001.112437e-01-1.095532e+016.270000e-281.080000e-26DOWNLUAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002608045.097297e-013.481923e-04CHOL7.527756e-04
ENSG00000260804-4.695341e-013.454193e-06KICH8.385781e-06
ENSG00000260804-3.170258e-013.091892e-14LUSC1.065157e-12

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lncRNA-Protein interaction for LINC01963

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for LINC01963

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for LINC01963

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
SLIRP
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000260804ENST00000562038exon_skip_4279chr1:36174897-36175008-13.29-0.1564MAP7D1ENST00000373151In-frame
ENSG00000260804ENST00000562038exon_skip_27178chr1:53233541-53233652-11.98-0.1099MAGOHENST00000371470In-frame
ENSG00000260804ENST00000562038exon_skip_90104chr12:10709907-10710114-25.27-0.1381YBX3ENST00000228251In-frame
ENSG00000260804ENST00000562038exon_skip_353172chr20:58898940-58898985-12.41-0.8864GNASENST00000371085,ENST00000371100In-frame
ENSG00000260804ENST00000562038exon_skip_517627chrX:154357250-154357274-7.57-0.4453FLNAENST00000369850In-frame
ENSG00000260804ENST00000562038exon_skip_84898chr12:62566013-62566031-5.17-0.3231MON2ENST00000393630In-frame
ENSG00000260804ENST00000562038exon_skip_48327chr10:26771074-26771089-7.36-0.8178ABI1ENST00000376142In-frame
ENSG00000260804ENST00000562038exon_skip_460899chr6:85538837-85538864-6.26-0.2845SNX14ENST00000314673In-frame
ENSG00000260804ENST00000562038exon_skip_381461chr3:12902772-12902822-9.55-0.2513IQSEC1ENST00000273221Frame-shift
ENSG00000260804ENST00000562038exon_skip_89597chr12:6672349-6672532-21.99-0.1301ZNF384ENST00000361959,ENST00000396801In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000260804ENST00000562038exon_skip_81540chr12:42384939-42384996-11.54-0.2098PPHLN1ENST00000395568In-frame
ENSG00000260804ENST00000562038exon_skip_361485chr21:29008239-29008307-11.22-0.1781RWDD2BENST00000493196Frame-shift
ENSG00000260804ENST00000562038exon_skip_111863chr14:23565815-23565892-15.46-0.2534AP1G2ENST00000308724,ENST00000397120Frame-shift
ENSG00000260804ENST00000562038exon_skip_132355chr16:1786756-1786955-23.11-0.1210NUBP2ENST00000262302Frame-shift
ENSG00000260804ENST00000562038exon_skip_504627chr9:83973901-83973973-14.00-0.3590HNRNPKENST00000351839,ENST00000360384In-frame

check buttonlncRNA targets by miRNA.
lncRNA targets by miRNA
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216219340-216219422187.00-78.0387NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216218760-216218849183.00-86.7682NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216218841-216218931182.00-75.2391NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216218437-216218528181.00-86.8774NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216220007-216220096178.00-88.6294NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216219169-216219247174.00-80.5576NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216217828-216217908171.00-87.3175NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216219867-216219955169.00-78.4185NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216217704-216217803168.00-78.8298NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216218354-216218440166.00-74.4087NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216218105-216218197163.00-74.1391NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216218663-216218757160.00-80.0689NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216217476-216217559159.00-77.3286NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216219777-216219876159.00-76.8195NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216218519-216218611157.00-80.9390NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216217982-216218066154.00-66.6279NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216217155-216217247153.00-76.4890NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216219075-216219156153.00-72.0278NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216218922-216219006151.00-62.1283NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216217046-216217122149.00-81.8977NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216219506-216219580145.00-66.8580NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216219677-216219760142.00-73.7785NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216220091-216220174141.00-67.5982NA
ENSG00000260804hsa-mir-3614ENST00000562038chr2:216217582-216217676140.00-68.3089NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216219360-216219438186.00-71.1382NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216219181-216219256184.00-72.1679NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216217136-216217223180.00-74.3682NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216217321-216217407180.00-72.5285NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216217730-216217825172.00-81.4194NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216218390-216218482169.00-67.6689NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216217986-216218068167.00-64.0677NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216219798-216219886162.00-75.6787NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216218691-216218760160.00-74.2577NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216218982-216219056156.00-64.3079NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216219530-216219616155.00-68.4280NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216217863-216217952152.00-80.4487NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216218763-216218850152.00-81.6782NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216218522-216218612150.00-79.9992NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216217647-216217729147.00-70.5471NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216218860-216218949146.00-79.1386NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216219049-216219131144.00-75.9184NA
ENSG00000260804hsa-mir-193bENST00000562038chr2:216219617-216219713140.00-70.4180NA

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Variants for LINC01963

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types
ENSG00000260804LINC01963,hsa-mir-3614,MEGF8UCEC,SKCM,TGCT,CHOL,BRCA,THYM
ENSG00000260804LINC01963,hsa-mir-3614,GPRASP2UCEC,SKCM,TGCT,BRCA,THYM
ENSG00000260804LINC01963,hsa-mir-3614,WDR35SKCM,TGCT,CHOL,MESO,THYM
ENSG00000260804LINC01963,hsa-mir-3614,UNC119BUCEC,SKCM,TGCT,CHOL,BRCA
ENSG00000260804LINC01963,hsa-mir-3614,IGIPUCEC,CHOL,BRCA,MESO,THYM
ENSG00000260804LINC01963,hsa-mir-3614,LTBP3UCEC,TGCT,CHOL,MESO,THYM
ENSG00000260804LINC01963,hsa-mir-3614,PHLDB1UCEC,SKCM,TGCT,CHOL,MESO
ENSG00000260804LINC01963,hsa-mir-3614,KANK2UCEC,TGCT,CHOL,MESO,THYM
ENSG00000260804LINC01963,hsa-mir-3614,ASB1UCEC,SKCM,TGCT,CHOL,BRCA
ENSG00000260804LINC01963,hsa-mir-3614,FAM172ASKCM,TGCT,CHOL,BRCA,MESO
ENSG00000260804LINC01963,hsa-mir-193b,LZTFL1HNSC,CHOL,GBM,MESO,PAAD
ENSG00000260804LINC01963,hsa-mir-193b,ZNF25HNSC,TGCT,CHOL,GBM,PAAD
ENSG00000260804LINC01963,hsa-mir-193b,SYNGR1HNSC,TGCT,CHOL,GBM,PAAD
ENSG00000260804LINC01963,hsa-mir-193b,TSPOAP1TGCT,CHOL,GBM,MESO,PAAD
ENSG00000260804LINC01963,hsa-mir-193b,USP27XHNSC,TGCT,CHOL,GBM,MESO,PAAD
ENSG00000260804LINC01963,hsa-mir-193b,KAT14HNSC,CHOL,GBM,MESO,PAAD
ENSG00000260804LINC01963,hsa-mir-193b,MADDHNSC,TGCT,CHOL,GBM,PAAD
ENSG00000260804LINC01963,hsa-mir-193b,BTBD9HNSC,CHOL,GBM,MESO,PAAD

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000260804.3ENST00000562038.1611820