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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000260711

Summary for RP11-747H7.3

check button Gene summary

Gene informationEnsembl ID

ENSG00000260711

Gene symbol

RP11-747H7.3

Gene name
HGNC
Entrez ID
Gene typesense_intronic
Synonyms
UniProtAcc

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Structure and expression level for RP11-747H7.3

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002607114.438997e+021.196940e+001.987038e-016.023739e+001.700000e-091.930000e-08UPSTAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value

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lncRNA-Protein interaction for RP11-747H7.3

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for RP11-747H7.3

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
MTRF1,NEIL1,CCNT2,RBM5,CCNL1,NKTR,WSB1,CCDC125,TC2N,TTLL3,ARHGEF38,N4BP2L2,RSRP1,OGT,RBM25,KHDC4,LRP5L,TIA1,GOLGA8B,CENATAC,PRPF39,RNPC3,ANKRD10,MSANTD2,RBM33,ANKMY1,CCDC14
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-747H7.3

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RP11-747H7.3

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name
LncEditing_287011ENSG00000260711.2chr1491757754-sense_intronicRP11-747H7.3ENST00000565058.2sense_intronicRP11-747H7.3-001
LncEditing_287017ENSG00000260711.2chr1491757792-sense_intronicRP11-747H7.3ENST00000565058.2sense_intronicRP11-747H7.3-001
LncEditing_287018ENSG00000260711.2chr1491757794-sense_intronicRP11-747H7.3ENST00000565058.2sense_intronicRP11-747H7.3-001
LncEditing_287022ENSG00000260711.2chr1491757824-sense_intronicRP11-747H7.3ENST00000565058.2sense_intronicRP11-747H7.3-001
LncEditing_287023ENSG00000260711.2chr1491757829-sense_intronicRP11-747H7.3ENST00000565058.2sense_intronicRP11-747H7.3-001
LncEditing_287029ENSG00000260711.2chr1491757864-sense_intronicRP11-747H7.3ENST00000565058.2sense_intronicRP11-747H7.3-001
LncEditing_287030ENSG00000260711.2chr1491757870-sense_intronicRP11-747H7.3ENST00000565058.2sense_intronicRP11-747H7.3-001
LncEditing_287065ENSG00000260711.2chr1491758016-sense_intronicRP11-747H7.3ENST00000565058.2sense_intronicRP11-747H7.3-001
LncEditing_287066ENSG00000260711.2chr1491758020-sense_intronicRP11-747H7.3ENST00000565058.2sense_intronicRP11-747H7.3-001

check buttonEdited-associated DElncRNAs in cancer.
Differentially expressed gene
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange
ENSG00000260711LncEditing_287011LUADchr14_91757754_-3.067218e+001.540254e+001.006277e+009.572065e+001.047909e-213.719219e-21UP
ENSG00000260711LncEditing_287017LUADchr14_91757792_-3.005391e+001.498394e+009.958819e-019.595275e+008.369368e-223.019947e-21UP
ENSG00000260711LncEditing_287018LUADchr14_91757794_-2.867148e+001.417099e+009.835980e-011.077944e+014.305168e-272.663054e-26UP
ENSG00000260711LncEditing_287030LUADchr14_91757870_-3.000790e+001.271886e+008.075111e-011.173475e+018.457794e-329.390320e-31UP
ENSG00000260711LncEditing_287065LUADchr14_91758016_-3.376346e+001.420046e+008.003042e-019.156223e+005.374545e-201.593957e-19UP
ENSG00000260711LncEditing_287011STADchr14_91757754_-1.648427e+009.805917e-011.334462e+006.505752e+007.730574e-111.296274e-10UP
ENSG00000260711LncEditing_287017STADchr14_91757792_-1.718118e+008.788495e-011.033975e+008.667250e+004.426832e-181.542390e-17UP
ENSG00000260711LncEditing_287018STADchr14_91757794_-1.637601e+008.527135e-011.062191e+009.187578e+004.017865e-201.820754e-19UP
ENSG00000260711LncEditing_287022STADchr14_91757824_-1.604723e+001.022460e+001.537800e+005.745976e+009.139222e-091.310047e-08UP
ENSG00000260711LncEditing_287023STADchr14_91757829_-1.684660e+001.010075e+001.355022e+005.357287e+008.448066e-081.130620e-07UP
ENSG00000260711LncEditing_287030STADchr14_91757870_-1.665419e+007.906323e-019.304000e-011.069922e+011.026399e-261.185326e-25UP
ENSG00000260711LncEditing_287065STADchr14_91758016_-1.504059e+009.731298e-011.591960e+006.539511e+006.172017e-111.042256e-10UP
ENSG00000260711LncEditing_287066STADchr14_91758020_-1.448375e+001.027498e+002.018980e+004.703693e+002.554976e-063.151357e-06UP
ENSG00000260711LncEditing_287011PRADchr14_91757754_-1.495103e+001.167216e+002.799759e+004.511038e+006.451116e-068.684760e-06UP
ENSG00000260711LncEditing_287017PRADchr14_91757792_-1.508293e+001.102145e+002.209444e+007.309526e+002.680863e-136.287261e-13UP
ENSG00000260711LncEditing_287018PRADchr14_91757794_-1.463110e+001.051064e+002.095612e+008.740773e+002.315199e-187.909147e-18UP
ENSG00000260711LncEditing_287030PRADchr14_91757870_-1.447820e+001.067843e+002.276958e+007.787509e+006.834299e-151.803156e-14UP
ENSG00000260711LncEditing_287065PRADchr14_91758016_-1.474992e+001.152349e+002.807968e+005.791117e+006.991969e-091.164015e-08UP
ENSG00000260711LncEditing_287011BRCAchr14_91757754_-2.599325e+001.350393e+001.058472e+001.508177e+012.134686e-519.579735e-51UP
ENSG00000260711LncEditing_287017BRCAchr14_91757792_-2.215696e+001.356091e+001.411820e+001.469666e+016.771879e-492.750367e-48UP
ENSG00000260711LncEditing_287018BRCAchr14_91757794_-2.221406e+001.221585e+001.159126e+001.745311e+013.259816e-683.159848e-67UP
ENSG00000260711LncEditing_287022BRCAchr14_91757824_-2.878793e+001.521732e+001.087252e+001.115299e+016.924099e-291.245995e-28UP
ENSG00000260711LncEditing_287029BRCAchr14_91757864_-2.387928e+001.529260e+001.555389e+001.075786e+015.442047e-279.095099e-27UP
ENSG00000260711LncEditing_287030BRCAchr14_91757870_-2.271445e+001.114441e+009.734349e-011.973262e+011.131403e-862.996472e-85UP
ENSG00000260711LncEditing_287065BRCAchr14_91758016_-2.277991e+001.352277e+001.329131e+001.480841e+011.292586e-495.369771e-49UP
ENSG00000260711LncEditing_287066BRCAchr14_91758020_-2.452422e+001.533857e+001.477011e+008.836054e+009.915907e-191.360163e-18UP
ENSG00000260711LncEditing_287018PAADchr14_91757794_-1.585344e+009.519989e-011.359131e+004.554538e+005.250088e-069.383135e-06UP
ENSG00000260711LncEditing_287030PAADchr14_91757870_-1.595656e+009.543494e-011.348508e+004.336851e+001.445383e-052.440445e-05UP
ENSG00000260711LncEditing_287065ESCAchr14_91758016_-1.745716e+008.542460e-019.698426e-015.269483e+001.368082e-072.489150e-07UP

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value
ENSG00000260711LncEditing_287011-3.487086e-015.883843e-037.867411e-03
ENSG00000260711LncEditing_287023-4.602054e-011.671181e-032.933004e-03
ENSG00000260711LncEditing_287030-3.321693e-011.278557e-044.701359e-04
ENSG00000260711LncEditing_287066-3.924100e-013.044589e-034.688405e-03
ENSG00000260711LncEditing_287011-3.775194e-013.628259e-024.073392e-02
ENSG00000260711LncEditing_287017-4.998635e-017.501852e-045.307419e-03
ENSG00000260711LncEditing_287018-4.599208e-012.810164e-043.785916e-03
ENSG00000260711LncEditing_287030-3.604633e-011.386073e-022.408929e-02
ENSG00000260711LncEditing_287065-4.875835e-012.558693e-039.442525e-03
ENSG00000260711LncEditing_287018-6.861153e-015.563857e-058.623979e-04
ENSG00000260711LncEditing_287011-4.200886e-016.758414e-041.050493e-03
ENSG00000260711LncEditing_287065-4.779884e-013.252182e-061.440087e-05

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation
ENSG00000260711ENSG00000175455CCDC14BRCA,LUAD,PAAD,PRAD,STADSTAD
ENSG00000260711ENSG00000236699ARHGEF38BRCA,ESCA,LUAD,PAAD,PRAD,STADSTAD

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000260711.2ENST00000565058.218011621704