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lncRNA: ENSG00000260231

Summary for KDM7A-DT

Gene summary

Gene information	Ensembl ID	ENSG00000260231
	Gene symbol	KDM7A-DT
	Gene name	KDM7A divergent transcript
	HGNC	48959
	Entrez ID	100134229
	Gene type	antisense
	Synonyms	07q34\|JHDM1D-AS1\|KDM7A-DT
	UniProtAcc

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Structure and expression level for KDM7A-DT

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000260231	1.542041e+02	-1.249763e+00	3.771449e-01	-3.313747e+00	9.205480e-04	3.222692e-03	DOWN	CHOL
ENSG00000260231	6.924165e+02	1.185029e+00	1.465353e-01	8.086992e+00	6.120000e-16	3.150000e-15	UP	LUSC

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID

Correlation

P-value

Cancer Type

Adjc.p-value

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lncRNA-Protein interaction for KDM7A-DT

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000260231	ENST00000566699	JHDM1D-AS1	ENSG00000125812	GZF1	61.98	95.4248	Q9H116	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000260231	ENST00000566699	JHDM1D-AS1	ENSG00000106344	RBM28	60.05	94.5742	Q9NW13	RBP	NA

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lncRNA-DNA interaction for KDM7A-DT

lncRNA targets the enhancer region and positively regulates the gene expression.

Only predicted by TDF

GPX2,TMEM168,HIBADH,TUBA4A,FAM234B,DNAJC30,CYCS,TATDN3,AKR1B1,CENPX,LIG3,PRR15,STMP1,ARF5,RRNAD1,AIMP2,DTD2,NEK3,NDRG3,TRMT6,MDH2,FAHD2B,PIGH,C7orf26,AGK,BUD23,PNKD,RBM28,TMED4,DPY19L1,DDX24,EPCAM,HILPDA,ATP1B1,POFUT1,NUAK2,COG5,SNAPC1,FAM200A,GFM2,GCLM,RTN4IP1,VPS50,BUD31,STRBP,ABCB8,CNOT4,CLCNKA,C2orf42,HUS1,BCAP29,SLC9A3,PARP12,ATP6V0E2,MTPN,ADSS2,ERP44,DMKN,STYXL1,ATXN10,SUSD4,DTNB,ANAPC7,RNF216,DENND11,MTURN,FAM220A,OPHN1,H2AZ2,GZF1,SLC35B4,ESYT2,TMEM251,CEBPZOS,MTOR,MPLKIP,TRAPPC14,SPATA2,NUDCD3,MAFB,ACTR3B,ERICH2,TMEM79,ARMC10,SNX8,GGPS1,UAP1,MTFMT,WHRN,RNF114,UBE2H,ZHX3,SYPL1,MRPS33,APOO,ABHD11,SLC4A11,GCC1,TSFM,HERPUD2,AAGAB,GON7,PSPH,CCDC125,SLC37A3,H2BC21,TMEM201,RHEB,ORC5,UQCRFS1,TMEM60,RAP1GAP,ABCF2,GALNT6,RNF24,HLCS,YAE1,DUS4L,NFS1,SMIM14,MOSPD3,LPIN2,BCL7B,LGALSL,TSPYL5,NSUN2,CSTB,CPVL,SFXN4,PREB,ZNF3,TMEM230,MARVELD2,TBC1D8,CREM,LRTOMT,CRCP,SYT7,FBXL8,SAYSD1,VOPP1,APMAP,UBTD1,ELOVL6,LRWD1,BTG2,TSNAX,YKT6,CPEB3,NDUFA5,MKRN1,SYNE2,TMPRSS13,MKKS,NOM1,LUC7L2,ARL4D,PRPSAP1,SLC25A13,CAB39L,TYW1,BBS4,TMEM50B,SSBP1,THNSL1,SNX13,PDCD6,SMYD3,CUL1,TMEM248,FASTK,STON2,ADK,TUFT1,RAD17,AVL9,ADAL,TRMT10A,FBXO4,SLC7A8

Exist in public source

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for KDM7A-DT

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000260231	ENST00000566699	exon_skip_75398	chr11:72692752-72692785	-12.04	-1.3378	ARAP1	ENST00000393605	In-frame

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000260231	ENST00000566699	exon_skip_436488	chr5:96726793-96726859	-9.29	-0.2903	CAST	ENST00000341926,ENST00000395813	In-frame

lncRNA targets by miRNA.

LncRNA Ensembl ID	miRNA ID	LncRNA ENST ID	Binding site in lncRNA	Score	Energy	Align Len	Public source
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140179117-140179239	220.00	-107.05	122	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140178011-140178116	211.00	-81.18	107	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140178983-140179091	200.00	-90.51	113	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140177547-140177651	198.00	-96.25	105	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140177382-140177501	194.00	-116.59	116	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140178716-140178825	188.00	-80.79	102	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140178445-140178560	182.00	-95.27	115	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140179477-140179582	182.00	-90.18	89	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140178110-140178220	175.00	-96.91	107	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140178826-140178932	174.00	-89.75	108	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140179302-140179411	174.00	-100.48	100	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140177732-140177843	169.00	-100.28	113	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140178584-140178703	169.00	-90.99	116	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140178340-140178445	168.00	-105.44	104	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140177839-140177938	164.00	-95.92	106	NA
ENSG00000260231	hsa-mir-222	ENST00000566699	chr7:140177276-140177388	163.00	-120.91	109	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140178063-140178164	188.00	-101.75	101	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140179109-140179223	182.00	-111.44	111	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140179289-140179379	176.00	-106.00	95	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140177686-140177781	169.00	-105.26	99	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140179374-140179476	165.00	-93.88	96	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140178686-140178778	164.00	-81.39	92	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140178998-140179095	163.00	-96.63	96	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140177853-140177953	159.00	-99.58	94	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140177322-140177417	158.00	-116.10	90	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140178511-140178605	157.00	-97.34	98	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140178874-140178976	156.00	-92.14	99	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140177503-140177600	152.00	-109.19	92	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140178779-140178878	147.00	-83.65	100	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140179486-140179577	147.00	-87.75	93	NA
ENSG00000260231	hsa-mir-561	ENST00000566699	chr7:140178351-140178464	144.00	-105.72	111	NA

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Variants for KDM7A-DT

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID	PC Gene ID	PC Gene Name	Positive correlated cancers	Cancer with PC gene up-regulation	Cancer with PC gene down-regulation
ENSG00000260231	ENSG00000123297	TSFM	CHOL,PAAD,TGCT,THCA,UVM		CHOL
ENSG00000260231	ENSG00000127838	PNKD	CHOL,KICH,KIRC,LIHC,TGCT		CHOL

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000260231.1	ENST00000566699.1	91	53	328

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential