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lncRNA: ENSG00000259495

Summary for RP11-210M15.2

Gene summary

Gene information	Ensembl ID	ENSG00000259495
	Gene symbol	RP11-210M15.2
	Gene name
	HGNC
	Entrez ID
	Gene type	lincRNA
	Synonyms
	UniProtAcc

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Structure and expression level for RP11-210M15.2

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000259495	3.018349e+02	4.246778e+00	5.382193e-01	7.890423e+00	3.010000e-15	7.800000e-14	UP	CHOL
ENSG00000259495	6.435641e+02	-1.439039e+00	1.682579e-01	-8.552578e+00	1.200000e-17	6.320000e-17	DOWN	KIRC
ENSG00000259495	2.684738e+03	1.277365e+00	3.060287e-01	4.174005e+00	2.990000e-05	9.270000e-05	UP	KICH

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000259495	4.378589e-01	2.629076e-03	CHOL	3.799060e-03

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lncRNA-Protein interaction for RP11-210M15.2

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000259495	ENST00000559267	RP11-210M15.2	ENSG00000198919	DZIP3	67.64	90.5586	Q86Y13	RBP,Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000259495	ENST00000559008	RP11-210M15.2	ENSG00000174282	ZBTB4	135.76	93.5537	Q9P1Z0	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000259495	ENST00000559008	RP11-210M15.2	ENSG00000137776	SLTM	109.25	94.4113	Q9NWH9	RBP	NA
ENSG00000259495	ENST00000559008	RP11-210M15.2	ENSG00000091009	RBM27	106.06	92.0328	Q9P2N5	RBP	NA
ENSG00000259495	ENST00000559267	RP11-210M15.2	ENSG00000137776	SLTM	64.83	90.9453	Q9NWH9	RBP	NA

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lncRNA-DNA interaction for RP11-210M15.2

lncRNA targets the enhancer region and positively regulates the gene expression.

Only predicted by TDF

CNOT4,CEBPZ,SON,NCOA2,GPBP1,AQR,ZHX3,MECP2,PURA,ZNF41,ZBTB4,DZIP3,SMAD4,ZFP62,SP3,ZFP91,ARID2,ZXDC,DDX42,BAZ2B,KRR1,VEZF1,NFXL1,RBM27,PURB,ADNP,GZF1,KMT2A,PUS7L,ZNF24,ASH1L,CASC3,GABPA,ARNT2,SP4,SALL2,MYNN,ZFP3,ZBTB5,THAP9,DDX6,ZFR,ZFX,THAP6,NOP9,NR2C2,ATF2

Exist in public source

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-210M15.2

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

ORF mutation

-lncRNA and exonskipping events are negatively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

LOF

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for RP11-210M15.2

RNA A-to-I editing events in lncRNA.

LncRNAediting ID	LncRNA Ensembl ID	Chromosome	Editing Position	Strand	Gene Type	Gene Name	Transcript ID	Transcript Type	Transcript Name
LncEditing_300686	ENSG00000259495.2	chr15	80379292	-	lincRNA	RP11-210M15.2	ENST00000559267.1	lincRNA	RP11-210M15.2-002
LncEditing_300690	ENSG00000259495.2	chr15	80379296	-	lincRNA	RP11-210M15.2	ENST00000559267.1	lincRNA	RP11-210M15.2-002
LncEditing_300692	ENSG00000259495.2	chr15	80379297	-	lincRNA	RP11-210M15.2	ENST00000559267.1	lincRNA	RP11-210M15.2-002
LncEditing_300694	ENSG00000259495.2	chr15	80379298	-	lincRNA	RP11-210M15.2	ENST00000559267.1	lincRNA	RP11-210M15.2-002
LncEditing_300702	ENSG00000259495.2	chr15	80379325	-	lincRNA	RP11-210M15.2	ENST00000559267.1	lincRNA	RP11-210M15.2-002
LncEditing_300704	ENSG00000259495.2	chr15	80379326	-	lincRNA	RP11-210M15.2	ENST00000559267.1	lincRNA	RP11-210M15.2-002
LncEditing_300710	ENSG00000259495.2	chr15	80379332	-	lincRNA	RP11-210M15.2	ENST00000559267.1	lincRNA	RP11-210M15.2-002

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID	LncRNA Index	Cancer Type	Chr_Postion_Strand	AVE1	AVE2	log2FC	W-value	P-value	Adjc.p-value	Change
ENSG00000259495	LncEditing_300686	LGG	chr15_80379292_-	3.729557e+00	2.206728e+00	1.320838e+00	1.121702e+01	3.364066e-29	1.799266e-28	UP
ENSG00000259495	LncEditing_300692	LGG	chr15_80379297_-	3.904173e+00	2.315254e+00	1.326531e+00	8.727952e+00	2.593257e-18	6.987937e-18	UP
ENSG00000259495	LncEditing_300694	LGG	chr15_80379298_-	3.934081e+00	2.308509e+00	1.300280e+00	8.871009e+00	7.248636e-19	2.030769e-18	UP
ENSG00000259495	LncEditing_300702	LGG	chr15_80379325_-	3.596490e+00	2.148780e+00	1.345765e+00	1.203307e+01	2.381467e-33	1.769806e-32	UP
ENSG00000259495	LncEditing_300704	LGG	chr15_80379326_-	3.646528e+00	2.292748e+00	1.493774e+00	8.960127e+00	3.243041e-19	9.269583e-19	UP
ENSG00000259495	LncEditing_300710	LGG	chr15_80379332_-	3.779462e+00	2.288419e+00	1.381540e+00	9.233546e+00	2.618182e-20	7.899302e-20	UP
ENSG00000259495	LncEditing_300710	KICH	chr15_80379332_-	9.804709e+00	5.336499e+00	1.139496e+00	3.663504e+00	2.487884e-04	6.623794e-04	UP

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID	LncRNA Index	Correlation	P-value	Adjc.p-value
ENSG00000259495	LncEditing_300702	-5.170716e-01	1.638051e-02	3.120640e-02
ENSG00000259495	LncEditing_300710	-3.788920e-01	4.723606e-03	5.446039e-03
ENSG00000259495	LncEditing_300690	-3.698775e-01	2.047103e-02	3.070654e-02
ENSG00000259495	LncEditing_300692	-3.373631e-01	4.420263e-02	4.420263e-02

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000259495.2	ENST00000559267.1	99	168	464
ENSG00000259495.2	ENST00000559008.2	90	338	66

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential