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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000255468

Summary for RP11-867G23.8

check button Gene summary

Gene informationEnsembl ID

ENSG00000255468

Gene symbol

RP11-867G23.8

Gene name
HGNC
Entrez ID

102724064

Gene typeantisense
Synonyms
UniProtAcc

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Structure and expression level for RP11-867G23.8

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002554681.097666e+022.626571e+003.988495e-016.585370e+004.540000e-114.310000e-09UPPCPG
ENSG000002554689.186403e+01-1.782198e+001.092251e-01-1.631674e+017.500000e-602.600000e-58DOWNLUSC
ENSG000002554681.308732e+02-1.278602e+001.523037e-01-8.395083e+004.660000e-173.800000e-16DOWNLUAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG00000255468-3.172594e-013.609459e-15LUAD5.154308e-14

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lncRNA-Protein interaction for RP11-867G23.8

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000255468ENST00000581155RP11-867G23.8ENSG00000141258SGSM215.5993.0972O43147TFNA
ENSG00000255468ENST00000581155RP11-867G23.8ENSG00000102878HSF44.4390.7641Q9ULV5TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000255468ENST00000581155RP11-867G23.8ENSG00000004534RBM622.9293.2133P78332RBPHigh-throughput data combine LncPro prediction

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lncRNA-DNA interaction for RP11-867G23.8

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
ATAT1,C1orf210,PHETA1,ATG13,TAF6L,ARFIP2,TRIM66,SLC29A2,SMPD3,CIRBP,MZF1,SART1,IQCE,TTC31,NDUFV1,SIRT3,RRNAD1,YIF1A,ACD,KIAA0895L,SMIM24,INTS5,DDX55,ULK3,CAPN10,CENATAC,HNF1A,B4GAT1,CHKA,PPP1R16A,CENPT,MMP15,VILL,RBM4,SLC2A11,CFAP410,GATD1,SUGP1,ARMC5,LTO1,PIDD1,ANAPC2,TMEM198,MEPCE,RBM14,ZBTB3,CALM3,SPATA2,AAAS,CPSF7,SFXN2,RMND5B,LIPT2,PCED1A,STX5,TMEM41B,EPN1,KLC4,HSF4,RAB17,SGSM2,RASSF7,SLC35C2,ASRGL1,HDHD3,CNNM3,RBM10,DDX51,TRIM52,PPFIBP2,SLC22A5,CUL9,TM7SF2,ZMAT1,ATG4B,HEMK1,ARFRP1,MYO1A,PCSK4,CCS,MEN1,SPIRE2,GIGYF1,GLYCTK,PLS1,DUSP28,ARFGAP2,ACOT8,C4orf19,CCDC142,RNASEH2C,GGT7,HEXD,SEMA4G,DPH7,MYRF,HINFP,CORO1B,USP20,ABHD8,IQCC
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-867G23.8

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000255468ENST00000580881exon_skip_44998chr10:110132304-110132400-9.12-0.1285ADD3ENST00000356080In-frame
ENSG00000255468ENST00000580881exon_skip_59476chr11:57815914-57816001-11.93-0.1754CTNND1ENST00000399050In-frame
ENSG00000255468ENST00000580881exon_skip_423795chr4:55888887-55888932-8.05-0.2176EXOC1ENST00000346134,ENST00000381295In-frame
ENSG00000255468ENST00000531602exon_skip_76520chr11:85990249-85990399-11.00-0.1048PICALMENST00000393346In-frame
ENSG00000255468ENST00000580881exon_skip_325891chr2:62987930-62988038-9.99-0.1514EHBP1ENST00000263991In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000255468ENST00000580881exon_skip_508298chr9:136445051-136445111-7.45-0.2661SEC16AENST00000313050In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RP11-867G23.8

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name
LncEditing_244101ENSG00000255468.5chr1166353477+antisenseRP11-867G23.8ENST00000581155.4antisenseRP11-867G23.8-007
LncEditing_244110ENSG00000255468.5chr1166353491+antisenseRP11-867G23.8ENST00000581155.4antisenseRP11-867G23.8-007
LncEditing_244116ENSG00000255468.5chr1166353504+antisenseRP11-867G23.8ENST00000581155.4antisenseRP11-867G23.8-007
LncEditing_244122ENSG00000255468.5chr1166353515+antisenseRP11-867G23.8ENST00000581155.4antisenseRP11-867G23.8-007
LncEditing_244125ENSG00000255468.5chr1166353518+antisenseRP11-867G23.8ENST00000581155.4antisenseRP11-867G23.8-007
LncEditing_244128ENSG00000255468.5chr1166353519+antisenseRP11-867G23.8ENST00000581155.4antisenseRP11-867G23.8-007
LncEditing_244134ENSG00000255468.5chr1166353530+antisenseRP11-867G23.8ENST00000581155.4antisenseRP11-867G23.8-007
LncEditing_244162ENSG00000255468.5chr1166353978+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244190ENSG00000255468.5chr1166354050+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244216ENSG00000255468.5chr1166354120+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244218ENSG00000255468.5chr1166354124+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244280ENSG00000255468.5chr1166355241+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244284ENSG00000255468.5chr1166355254+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244288ENSG00000255468.5chr1166355285+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244300ENSG00000255468.5chr1166355382+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244314ENSG00000255468.5chr1166355850+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244336ENSG00000255468.5chr1166355967+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244342ENSG00000255468.5chr1166355989+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244350ENSG00000255468.5chr1166356030+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244358ENSG00000255468.5chr1166356039+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244372ENSG00000255468.5chr1166356110+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244374ENSG00000255468.5chr1166356122+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244380ENSG00000255468.5chr1166356660+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244490ENSG00000255468.5chr1166357642+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244546ENSG00000255468.5chr1166357963+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244554ENSG00000255468.5chr1166357984+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244584ENSG00000255468.5chr1166358203+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244600ENSG00000255468.5chr1166358281+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244612ENSG00000255468.5chr1166358313+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244614ENSG00000255468.5chr1166358314+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244632ENSG00000255468.5chr1166358454+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244634ENSG00000255468.5chr1166358455+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244752ENSG00000255468.5chr1166360303+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004
LncEditing_244758ENSG00000255468.5chr1166360317+antisenseRP11-867G23.8ENST00000580881.1antisenseRP11-867G23.8-004

check buttonEdited-associated DElncRNAs in cancer.
Differentially expressed gene
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange
ENSG00000255468LncEditing_244101LIHCchr11_66353477_+5.442881e+002.630968e+009.534918e-018.942529e+003.803649e-191.450820e-18UP
ENSG00000255468LncEditing_244101PCPGchr11_66353477_+1.998717e+001.419930e+002.027352e+003.881403e+001.038556e-041.497740e-04UP
ENSG00000255468LncEditing_244101STADchr11_66353477_+7.662721e+003.666785e+009.404321e-011.038371e+012.941227e-252.752834e-24UP
ENSG00000255468LncEditing_244110STADchr11_66353491_+7.483939e+005.018244e+001.734259e+005.331577e+009.736379e-081.298184e-07UP
ENSG00000255468LncEditing_244116STADchr11_66353504_+9.441920e+004.840908e+001.037557e+006.720136e+001.815546e-113.229643e-11UP
ENSG00000255468LncEditing_244122STADchr11_66353515_+8.791340e+004.381768e+009.954507e-017.919789e+002.379146e-156.105621e-15UP
ENSG00000255468LncEditing_244125STADchr11_66353518_+9.266677e+004.519560e+009.653724e-017.342285e+002.099776e-134.414688e-13UP
ENSG00000255468LncEditing_244128STADchr11_66353519_+9.494284e+004.717978e+009.911880e-016.521660e+006.953350e-111.171435e-10UP
ENSG00000255468LncEditing_244134STADchr11_66353530_+8.907901e+004.409346e+009.856869e-018.389338e+004.888879e-171.476978e-16UP
ENSG00000255468LncEditing_244216STADchr11_66354120_+1.077703e+014.564721e+008.068670e-018.226368e+001.929760e-165.429108e-16UP
ENSG00000255468LncEditing_244218STADchr11_66354124_+1.042421e+014.453663e+008.150794e-018.563214e+001.097638e-173.588625e-17UP
ENSG00000255468LncEditing_244280STADchr11_66355241_+1.085599e+014.758936e+008.404915e-016.793341e+001.095659e-111.981039e-11UP
ENSG00000255468LncEditing_244284STADchr11_66355254_+9.517026e+004.495927e+009.243065e-018.404311e+004.303798e-171.314081e-16UP
ENSG00000255468LncEditing_244314STADchr11_66355850_+1.011783e+014.308650e+008.119573e-019.087866e+001.010023e-194.317473e-19UP
ENSG00000255468LncEditing_244336STADchr11_66355967_+9.779762e+004.146116e+008.077291e-019.173401e+004.583263e-202.038271e-19UP
ENSG00000255468LncEditing_244350STADchr11_66356030_+1.070829e+014.537323e+008.072233e-018.014359e+001.107128e-152.941388e-15UP
ENSG00000255468LncEditing_244380STADchr11_66356660_+1.099357e+014.648547e+008.052775e-017.081863e+001.422290e-122.759782e-12UP
ENSG00000255468LncEditing_244546STADchr11_66357963_+1.062067e+014.588778e+008.259736e-018.316059e+009.093659e-172.663010e-16UP
ENSG00000255468LncEditing_244554STADchr11_66357984_+1.094155e+014.636413e+008.072744e-017.711151e+001.246878e-142.908029e-14UP
ENSG00000255468LncEditing_244584STADchr11_66358203_+1.003242e+014.595635e+008.878371e-017.274363e+003.480599e-137.161232e-13UP
ENSG00000255468LncEditing_244600STADchr11_66358281_+1.050673e+014.660273e+008.526402e-017.421508e+001.157938e-132.478577e-13UP
ENSG00000255468LncEditing_244612STADchr11_66358313_+9.696079e+004.131791e+008.125891e-011.015311e+013.209656e-242.719661e-23UP
ENSG00000255468LncEditing_244614STADchr11_66358314_+9.778955e+004.203626e+008.209871e-019.790417e+001.237838e-227.948807e-22UP
ENSG00000255468LncEditing_244632STADchr11_66358454_+9.575672e+004.704582e+009.753175e-016.961999e+003.354790e-126.321131e-12UP
ENSG00000255468LncEditing_244634STADchr11_66358455_+9.452725e+004.361134e+008.960356e-018.588406e+008.818410e-182.957368e-17UP
ENSG00000255468LncEditing_244752STADchr11_66360303_+1.067877e+014.579839e+008.187479e-017.946083e+001.925020e-154.993894e-15UP
ENSG00000255468LncEditing_244101PAADchr11_66353477_+4.641507e+002.156040e+009.039878e-014.457998e+008.272881e-061.432829e-05UP
ENSG00000255468LncEditing_244110ESCAchr11_66353491_+5.738273e+002.894568e+001.012896e+004.429522e+009.444200e-061.328526e-05UP

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value
ENSG00000255468LncEditing_244116-3.685068e-011.274546e-021.456035e-02
ENSG00000255468LncEditing_244122-4.171330e-016.456856e-052.885152e-04
ENSG00000255468LncEditing_244125-5.671166e-013.762864e-072.213819e-05
ENSG00000255468LncEditing_244128-3.863037e-014.275362e-035.991977e-03
ENSG00000255468LncEditing_244134-4.016690e-011.838451e-046.158386e-04
ENSG00000255468LncEditing_244190-3.091374e-013.251788e-023.317576e-02
ENSG00000255468LncEditing_244216-3.685228e-018.455125e-031.032730e-02
ENSG00000255468LncEditing_244280-5.015108e-011.144049e-032.294598e-03
ENSG00000255468LncEditing_244284-3.947610e-019.470165e-041.996669e-03
ENSG00000255468LncEditing_244288-3.200263e-011.722461e-021.930249e-02
ENSG00000255468LncEditing_244342-3.906375e-016.049589e-037.969342e-03
ENSG00000255468LncEditing_2443583.364975e-017.492276e-039.384592e-03
ENSG00000255468LncEditing_244374-3.096863e-012.700447e-022.811970e-02
ENSG00000255468LncEditing_244490-3.241313e-012.165494e-022.366624e-02
ENSG00000255468LncEditing_244554-4.179623e-014.277559e-035.991977e-03
ENSG00000255468LncEditing_244101-5.552037e-017.543650e-052.780145e-03
ENSG00000255468LncEditing_244110-4.842357e-013.049858e-023.739824e-02
ENSG00000255468LncEditing_244116-6.339443e-011.490916e-022.429925e-02
ENSG00000255468LncEditing_244128-5.189626e-014.744627e-024.794050e-02
ENSG00000255468LncEditing_244134-4.900939e-011.505041e-022.432163e-02
ENSG00000255468LncEditing_244162-4.629089e-011.979513e-022.918127e-02
ENSG00000255468LncEditing_244300-6.056077e-011.291216e-022.289208e-02
ENSG00000255468LncEditing_244342-5.775331e-011.519125e-022.432163e-02
ENSG00000255468LncEditing_244350-5.974168e-011.453533e-022.429925e-02
ENSG00000255468LncEditing_244372-4.943808e-014.366595e-024.613940e-02
ENSG00000255468LncEditing_244374-6.865287e-018.288824e-045.506958e-03
ENSG00000255468LncEditing_244490-4.653969e-013.349969e-023.933983e-02
ENSG00000255468LncEditing_244584-4.717024e-013.086725e-023.742575e-02
ENSG00000255468LncEditing_244758-4.829817e-013.099544e-023.742575e-02

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000255468.5ENST00000581155.4138100513
ENSG00000255468.5ENST00000531602.1692060
ENSG00000255468.5ENST00000580881.111888444