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lncRNA: ENSG00000254473

Summary for UBQLN1-AS1

Gene summary

Gene information	Ensembl ID	ENSG00000254473
	Gene symbol	UBQLN1-AS1
	Gene name	UBQLN1 antisense RNA 1
	HGNC	55518
	Entrez ID	105376114
	Gene type	antisense
	Synonyms	UBQLN1-AS1\|RP11-522I20.3\|09q21.32
	UniProtAcc

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Structure and expression level for UBQLN1-AS1

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000254473	7.581942e+01	-1.582720e+00	2.639388e-01	-5.996543e+00	2.020000e-09	2.130000e-08	DOWN	CHOL

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000254473	-5.384914e-01	5.235686e-08	KICH	2.256665e-07
ENSG00000254473	-3.851366e-01	6.209925e-23	KIRC	7.871736e-22

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lncRNA-Protein interaction for UBQLN1-AS1

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000254473	ENST00000531661	RP11-522I20.3	ENSG00000080503	SMARCA2	83.31	91.167	P51531	Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000254473	ENST00000531661	RP11-522I20.3	ENSG00000117707	PROX1	63.26	90.7803	Q92786	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000254473	ENST00000531661	RP11-522I20.3	ENSG00000198000	NOL8	61.32	90.6105	Q76FK4	RBP	NA

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lncRNA-DNA interaction for UBQLN1-AS1

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for UBQLN1-AS1

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

ETV6,DMWD,SEPTIN9,ARAP1,MYH9,TNFRSF1A,NUP62,ACTN4,STING1,ZYX,CHPF2,STAT6,TTYH3,ANXA2,LDLR,MYO9B,MGAT4B,CCDC9,PLEKHG2

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000254473	ENST00000531661	exon_skip_98384	chr12:124327408-124327633	-23.86	-0.1125	NCOR2	ENST00000405201	In-frame
ENSG00000254473	ENST00000531661	exon_skip_353530	chr20:62304460-62304577	-14.50	-0.1408	ADRM1	ENST00000253003	In-frame
ENSG00000254473	ENST00000531661	exon_skip_27065	chr1:52906518-52906611	-17.78	-0.3951	ECHDC2	ENST00000371522	In-frame

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000254473	ENST00000531661	exon_skip_494079	chr8:144099080-144099205	-18.36	-0.1611	SHARPIN	ENST00000398712	Frame-shift

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for UBQLN1-AS1

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID	LncRNA ENST ID	PC Gene Name	PC Gene ID	PC ENST ID	dG	nDG	Cancer with PC gene up-regulation	Cancer with PC gene Down-regulation
ENSG00000254473	ENST00000524818	NUP62	ENSG00000213024	ENST00000597029	-0.1743	21	CHOL	-
ENSG00000254473	ENST00000524818	NUP62	ENSG00000213024	ENST00000597723	-0.1743	21	CHOL	-
ENSG00000254473	ENST00000524818	NUP62	ENSG00000213024	ENST00000596217	-0.1743	21	CHOL	-
ENSG00000254473	ENST00000531661	NUP62	ENSG00000213024	ENST00000597029	-0.1027	807	CHOL	-
ENSG00000254473	ENST00000531661	NUP62	ENSG00000213024	ENST00000597723	-0.1027	807	CHOL	-
ENSG00000254473	ENST00000531661	NUP62	ENSG00000213024	ENST00000596217	-0.1027	808	CHOL	-

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000254473.1	ENST00000524818.1	78	49	285
ENSG00000254473.1	ENST00000531661.1	135	84	488

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential