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lncRNA: ENSG00000247240

Summary for UBL7-DT

Gene summary

Gene information	Ensembl ID	ENSG00000247240
	Gene symbol	UBL7-DT
	Gene name	UBL7 divergent transcript
	HGNC	48614
	Entrez ID	440288
	Gene type	antisense
	Synonyms	UBL7-AS1\|UBL7-DT\|15q24.1
	UniProtAcc

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Structure and expression level for UBL7-DT

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000247240	1.008408e+02	1.218774e+00	2.638750e-01	4.618755e+00	3.860000e-06	2.740000e-05	UP	GBM
ENSG00000247240	1.527734e+02	1.201915e+00	3.523416e-01	3.411221e+00	6.467270e-04	5.581986e-03	UP	CESC

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID

Correlation

P-value

Cancer Type

Adjc.p-value

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lncRNA-Protein interaction for UBL7-DT

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000247240	ENST00000564621	UBL7-AS1	ENSG00000155827	RNF20	96.69	90.0216	Q5VTR2	Epi	NA
ENSG00000247240	ENST00000564621	UBL7-AS1	ENSG00000009954	BAZ1B	88.69	91.5191	Q9UIG0	Epi	Predict
ENSG00000247240	ENST00000564621	UBL7-AS1	ENSG00000012048	BRCA1	65.42	93.7291	P38398	RBP,Epi	ChIP-seq
ENSG00000247240	ENST00000564621	UBL7-AS1	ENSG00000115524	SF3B1	58.83	92.4738	O75533	Epi	NA
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000128908	INO80	58.22	92.0031	Q9ULG1	Epi	NA
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000149311	ATM	53.69	90.4255	Q13315	Epi	NA
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000253729	PRKDC	43.46	91.6426	P78527	Epi	NA
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000122966	CIT	36.84	92.242	O14578	Epi	NA
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000169679	BUB1	35.22	91.4121	O43683	Epi	NA
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000147130	ZMYM3	34.83	91.5541	Q14202	Epi	NA
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000183337	BCOR	34.52	91.0531	Q6W2J9	Epi	ChIP-seq
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000139613	SMARCC2	32.03	91.375	Q8TAQ2	Epi	ChIP-seq
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000156650	KAT6B	8.1	93.1981	Q8WYB5	Epi	NA
ENSG00000247240	ENST00000499217	UBL7-AS1	ENSG00000121741	ZMYM2	36.87	90.4593	Q9UBW7	Epi	NA
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000009954	BAZ1B	55.48	90.4138	Q9UIG0	Epi	Predict
ENSG00000247240	ENST00000564137	UBL7-AS1	ENSG00000183495	EP400	49.48	90.4078	Q96L91	Epi	NA
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000012048	BRCA1	36.1	92.1559	P38398	RBP,Epi	ChIP-seq
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000115524	SF3B1	30.76	93.572	O75533	Epi	NA
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000164190	NIPBL	24.97	94.2745	Q6KC79	Epi	ChIP-seq
ENSG00000247240	ENST00000564621	UBL7-AS1	ENSG00000147133	TAF1	67.26	93.571	P21675	Epi	ChIP-seq
ENSG00000247240	ENST00000499217	UBL7-AS1	ENSG00000164190	NIPBL	74.55	90.1152	Q6KC79	Epi	ChIP-seq

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000247240	ENST00000564621	UBL7-AS1	ENSG00000198521	ZNF43	54.67	92.1812	P17038	TF	NA
ENSG00000247240	ENST00000564621	UBL7-AS1	ENSG00000198538	ZNF28	42.74	90.253	P17035	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000247240	ENST00000499217	UBL7-AS1	ENSG00000091009	RBM27	83.06	91.7757	Q9P2N5	RBP	NA
ENSG00000247240	ENST00000499217	UBL7-AS1	ENSG00000012048	BRCA1	79.7	91.4643	P38398	RBP,Epi	ChIP-seq
ENSG00000247240	ENST00000499217	UBL7-AS1	ENSG00000067596	DHX8	66.18	92.5336	Q14562	RBP	NA
ENSG00000247240	ENST00000564621	UBL7-AS1	ENSG00000091009	RBM27	69.4	95.2994	Q9P2N5	RBP	NA
ENSG00000247240	ENST00000564621	UBL7-AS1	ENSG00000012048	BRCA1	65.42	94.0124	P38398	RBP,Epi	ChIP-seq
ENSG00000247240	ENST00000564621	UBL7-AS1	ENSG00000162775	RBM15	61.94	90.6258	Q96T37	RBP	iCLIP
ENSG00000247240	ENST00000564621	UBL7-AS1	ENSG00000067596	DHX8	57.99	91.2667	Q14562	RBP	NA
ENSG00000247240	ENST00000564137	UBL7-AS1	ENSG00000125676	THOC2	58.28	91.321	Q8NI27	RBP	NA
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000114127	XRN1	42.26	90.6142	Q8IZH2	RBP	NA
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000012048	BRCA1	36.1	93.3667	P38398	RBP,Epi	ChIP-seq
ENSG00000247240	ENST00000568853	UBL7-AS1	ENSG00000067596	DHX8	25.16	90.479	Q14562	RBP	NA

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lncRNA-DNA interaction for UBL7-DT

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for UBL7-DT

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

ATP5F1D,INAFM1,DAPK3,S100A11,RAB4B,TOM1,TOLLIP,TNFSF12,MAP1LC3A,FKBP8,FAM234A,METTL26,EDF1,CLTB

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

ORF mutation

-lncRNA and exonskipping events are negatively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

LOF

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for UBL7-DT

RNA A-to-I editing events in lncRNA.

LncRNAediting ID	LncRNA Ensembl ID	Chromosome	Editing Position	Strand	Gene Type	Gene Name	Transcript ID	Transcript Type	Transcript Name
LncEditing_298038	ENSG00000247240.6	chr15	74466044	+	antisense	UBL7-AS1	ENST00000568853.1	antisense	UBL7-AS1-006

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID	LncRNA Index	Cancer Type	Chr_Postion_Strand	AVE1	AVE2	log2FC	W-value	P-value	Adjc.p-value	Change
ENSG00000247240	LncEditing_298038	GBM	chr15_74466044_+	1.943760e+00	1.330258e+00	1.827674e+00	4.176704e+00	2.957638e-05	4.506081e-05	UP
ENSG00000247240	LncEditing_298038	LUSC	chr15_74466044_+	2.500672e+00	1.874568e+00	2.405247e+00	5.784842e+00	7.258045e-09	9.121978e-09	UP
ENSG00000247240	LncEditing_298038	OV	chr15_74466044_+	1.450942e+00	1.179922e+00	3.352356e+00	3.863478e+00	1.117838e-04	1.280813e-04	UP
ENSG00000247240	LncEditing_298038	TGCT	chr15_74466044_+	2.075822e+00	1.597318e+00	2.645287e+00	3.431560e+00	6.001203e-04	7.415384e-04	UP
ENSG00000247240	LncEditing_298038	STAD	chr15_74466044_+	1.327583e+00	1.024961e+00	2.679293e+00	4.442287e+00	8.900791e-06	1.064823e-05	UP
ENSG00000247240	LncEditing_298038	CESC	chr15_74466044_+	2.072778e+00	1.707959e+00	3.580471e+00	2.936361e+00	3.320881e-03	3.516226e-03	UP
ENSG00000247240	LncEditing_298038	ESCA	chr15_74466044_+	1.292784e+00	9.860809e-01	2.559487e+00	4.217015e+00	2.475570e-05	3.317643e-05	UP

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID	LncRNA Index	Correlation	P-value	Adjc.p-value
ENSG00000247240	LncEditing_298038	-3.061465e-01	4.378821e-03	6.355880e-03
ENSG00000247240	LncEditing_298038	-4.784330e-01	2.092466e-02	3.090412e-02
ENSG00000247240	LncEditing_298038	-3.327829e-01	2.730078e-03	5.460155e-03
ENSG00000247240	LncEditing_298038	-4.642621e-01	1.441508e-04	5.139924e-04
ENSG00000247240	LncEditing_298038	-5.125240e-01	1.665839e-04	2.959752e-03

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID	LncRNA ENST ID	PC Gene Name	PC Gene ID	PC ENST ID	dG	nDG	Cancer with PC gene up-regulation	Cancer with PC gene Down-regulation
ENSG00000247240	ENST00000564137	TOLLIP	ENSG00000078902	ENST00000527938	-0.1372	1	-	GBM
ENSG00000247240	ENST00000564137	FKBP8	ENSG00000105701	ENST00000596015	-0.1973	284	-	GBM
ENSG00000247240	ENST00000564137	FKBP8	ENSG00000105701	ENST00000606531	-0.1649	328	-	GBM
ENSG00000247240	ENST00000499217	TOLLIP	ENSG00000078902	ENST00000527938	-0.1331	99	-	GBM
ENSG00000247240	ENST00000499217	FKBP8	ENSG00000105701	ENST00000596015	-0.1973	748	-	GBM
ENSG00000247240	ENST00000499217	FKBP8	ENSG00000105701	ENST00000606531	-0.1961	309	-	GBM
ENSG00000247240	ENST00000567286	TOLLIP	ENSG00000078902	ENST00000527938	-0.1185	308	-	GBM
ENSG00000247240	ENST00000567286	FKBP8	ENSG00000105701	ENST00000596015	-0.2077	9	-	GBM
ENSG00000247240	ENST00000567286	FKBP8	ENSG00000105701	ENST00000606531	-0.1195	219	-	GBM
ENSG00000247240	ENST00000564621	TOLLIP	ENSG00000078902	ENST00000527938	-0.1566	1156	-	GBM
ENSG00000247240	ENST00000564621	FKBP8	ENSG00000105701	ENST00000596015	-0.3330	744	-	GBM
ENSG00000247240	ENST00000564621	FKBP8	ENSG00000105701	ENST00000606531	-0.1961	238	-	GBM
ENSG00000247240	ENST00000568853	TOLLIP	ENSG00000078902	ENST00000527938	-0.1331	20	-	GBM
ENSG00000247240	ENST00000568853	FKBP8	ENSG00000105701	ENST00000597960	-0.1031	1	-	GBM
ENSG00000247240	ENST00000568853	FKBP8	ENSG00000105701	ENST00000544835	-0.1031	1	-	GBM
ENSG00000247240	ENST00000568853	FKBP8	ENSG00000105701	ENST00000596558	-0.1031	1	-	GBM
ENSG00000247240	ENST00000568853	FKBP8	ENSG00000105701	ENST00000222308	-0.1031	1	-	GBM
ENSG00000247240	ENST00000568853	FKBP8	ENSG00000105701	ENST00000608443	-0.1031	1	-	GBM
ENSG00000247240	ENST00000568853	FKBP8	ENSG00000105701	ENST00000601844	-0.1081	1	-	GBM
ENSG00000247240	ENST00000568853	FKBP8	ENSG00000105701	ENST00000596015	-0.1389	5	-	GBM
ENSG00000247240	ENST00000568853	FKBP8	ENSG00000105701	ENST00000606531	-0.1612	114	-	GBM

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000247240.6	ENST00000564137.4	44	65	196
ENSG00000247240.6	ENST00000499217.5	93	282	560
ENSG00000247240.6	ENST00000567286.4	135	404	0
ENSG00000247240.6	ENST00000564621.1	109	240	569
ENSG00000247240.6	ENST00000568853.1	167	983	1486

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential