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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000247095

Summary for MIR210HG

check button Gene summary

Gene informationEnsembl ID

ENSG00000247095

Gene symbol

MIR210HG

Gene nameMIR210 host gene
HGNC

39524

Entrez ID

100506211

Gene typelincRNA
Synonyms11p15.5|MIR210HG
UniProtAcc

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Structure and expression level for MIR210HG

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002470953.774468e+021.934088e+005.112840e-013.782806e+001.550700e-047.283830e-04UPGBM
ENSG000002470951.367392e+033.255849e+001.266357e-012.571035e+018.950000e-1465.490000e-143UPKIRC
ENSG000002470955.252565e+021.402561e+002.956930e-014.743302e+002.100000e-061.730000e-05UPBLCA
ENSG000002470956.070657e+021.832042e+002.247283e-018.152250e+003.570000e-165.700000e-15UPKIRP
ENSG000002470954.255324e+022.019321e+001.762015e-011.146030e+012.090000e-306.990000e-29UPUCEC
ENSG000002470953.089720e+023.343153e+007.881318e-014.241871e+002.220000e-055.161850e-04UPPCPG
ENSG000002470956.128718e+021.957082e+001.461058e-011.339496e+016.470000e-411.110000e-39UPLUSC
ENSG000002470952.086243e+021.626269e+001.257189e-011.293576e+012.830000e-383.970000e-37UPBRCA
ENSG000002470953.400610e+021.130269e+001.396611e-018.092941e+005.820000e-164.400000e-15UPLUAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002470955.963201e-011.541761e-05CHOL9.044815e-05
ENSG000002470953.016202e-012.969672e-14KIRC1.147084e-13
ENSG000002470953.204795e-015.257981e-11LIHC2.126832e-10
ENSG000002470953.264521e-014.824242e-16UCEC6.214278e-15

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lncRNA-Protein interaction for MIR210HG

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000247095ENST00000534540MIR210HGENSG00000154832CXXC114.3392.1932Q9P0U4TF,EpiNA
ENSG00000247095ENST00000534540MIR210HGENSG00000104885DOT1L14.0992.0311Q8TEK3TF,EpiPredict
ENSG00000247095ENST00000500447MIR210HGENSG00000104885DOT1L51.1395.903Q8TEK3TF,EpiPredict
ENSG00000247095ENST00000533920MIR210HGENSG00000104885DOT1L9.3992.6081Q8TEK3TF,EpiPredict

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000247095ENST00000500447MIR210HGENSG00000104885DOT1L51.1396.1275Q8TEK3TF,EpiPredict
ENSG00000247095ENST00000500447MIR210HGENSG00000069011PITX140.0693.0182P78337TFNA
ENSG00000247095ENST00000500447MIR210HGENSG00000185507IRF727.7892.0078Q92985TFNA
ENSG00000247095ENST00000500447MIR210HGENSG00000102878HSF417.1491.5711Q9ULV5TFNA
ENSG00000247095ENST00000533920MIR210HGENSG00000104885DOT1L9.3992.3239Q8TEK3TF,EpiPredict
ENSG00000247095ENST00000533920MIR210HGENSG00000117000RLF7.4594.7466Q13129TFNA
ENSG00000247095ENST00000500447MIR210HGENSG00000126456IRF35.0393.6603Q14653TFChIP-seq
ENSG00000247095ENST00000534540MIR210HGENSG00000154832CXXC114.3391.3261Q9P0U4TF,EpiNA
ENSG00000247095ENST00000534540MIR210HGENSG00000104885DOT1L14.0991.2482Q8TEK3TF,EpiPredict
ENSG00000247095ENST00000534540MIR210HGENSG00000117000RLF11.6794.4874Q13129TFNA
ENSG00000247095ENST00000528245MIR210HGENSG00000117000RLF11.492.4059Q13129TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000247095ENST00000500447MIR210HGENSG00000131652THOC650.3490.3549Q86W42RBPNA
ENSG00000247095ENST00000500447MIR210HGENSG00000204356NELFE29.3694.7154P18615RBPNA

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lncRNA-DNA interaction for MIR210HG

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
PHF1,RNH1,DEAF1,GLI4,DDX49,CENPT,NOL3,MYPOP,HSF4,THOC6,RBM42,IRF3,JMJD6,DDX56,THAP8,MZF1,PHF19,DOT1L,LSM4,PITX1,CREB3,TIGD1,RNPS1,NR2F6,MBD3,PCBP4,THAP3,DHX34,DDX41,HINFP,EIF3B,PPIE,NELFE,IRF7,RALY,USF1,CXXC1,SNRPA
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.
Only predicted by TDF
MYPOP,PHF19,MZF1,RBM42
Exist in public source
NA

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.
Only predicted by TDF
FLI1
Exist in public source
NA

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lncRNA-RNA interaction for MIR210HG

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
ZEB2,FLI1,MEF2C,QKI,NCOA1,CSDE1,LARP4,ETS1,ZEB1
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000247095ENST00000534540exon_skip_302276chr19:10808568-10808580-5.50-0.5000DNM2ENST00000355667In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000247095ENST00000534540exon_skip_48716chr10:34372497-34372536-6.69-0.3186PARD3ENST00000374789In-frame
ENSG00000247095ENST00000534540exon_skip_33516chr1:156938417-156938513-15.50-0.1782ARHGEF11ENST00000361409In-frame
ENSG00000247095ENST00000534540exon_skip_466113chr7:48099669-48099787-8.90-0.1236UPP1ENST00000331803,ENST00000395564Frame-shift
ENSG00000247095ENST00000533920exon_skip_424741chr4:83458345-83458429-8.51-0.1251MRPS18CENST00000295491In-frame
ENSG00000247095ENST00000534540exon_skip_305632chr19:35262545-35262692-18.02-0.1234LSRENST00000361790In-frame
ENSG00000247095ENST00000534540exon_skip_476181chr7:73543547-73543644-13.07-0.1654BCL7BENST00000223368Frame-shift
ENSG00000247095ENST00000534540exon_skip_71438chr11:60941121-60941290-21.67-0.1416SLC15A3ENST00000227880Frame-shift

check buttonlncRNA targets by miRNA.
lncRNA targets by miRNA
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source
ENSG00000247095hsa-mir-139ENST00000500447chr11:566410-566480179.00-55.3370NA
ENSG00000247095hsa-mir-139ENST00000500447chr11:567154-567219175.00-66.9864NA
ENSG00000247095hsa-mir-139ENST00000500447chr11:567520-567591170.00-59.4264NA
ENSG00000247095hsa-mir-139ENST00000500447chr11:565825-565894166.00-66.7667NA
ENSG00000247095hsa-mir-139ENST00000500447chr11:567459-567529156.00-55.9267NA
ENSG00000247095hsa-mir-139ENST00000500447chr11:565679-565745152.00-72.4262NA
ENSG00000247095hsa-mir-139ENST00000500447chr11:565963-566027151.00-61.0360NA
ENSG00000247095hsa-mir-139ENST00000500447chr11:566040-566112151.00-63.9669NA
ENSG00000247095hsa-mir-139ENST00000500447chr11:566743-566809151.00-58.0367NA
ENSG00000247095hsa-mir-139ENST00000500447chr11:566579-566641148.00-51.5059NA
ENSG00000247095hsa-mir-139ENST00000500447chr11:566822-566897148.00-71.8572NA
ENSG00000247095hsa-mir-139ENST00000500447chr11:566483-566550145.00-58.0065NA
ENSG00000247095hsa-mir-139ENST00000500447chr11:566957-567028145.00-71.7969NA
ENSG00000247095hsa-mir-139ENST00000500447chr11:566887-566950142.00-67.5361NA
ENSG00000247095hsa-mir-139ENST00000528245chr11:567090-567161181.00-78.5369NA
ENSG00000247095hsa-mir-139ENST00000528245chr11:567365-567434166.00-66.7667NA
ENSG00000247095hsa-mir-139ENST00000528245chr11:567503-567567151.00-61.0360NA
ENSG00000247095hsa-mir-139ENST00000528245chr11:567580-567652151.00-63.9669NA
ENSG00000247095hsa-mir-139ENST00000528245chr11:567180-567249145.00-59.8366NA
ENSG00000247095hsa-mir-139ENST00000533920chr11:567644-567713166.00-66.7667NA
ENSG00000247095hsa-mir-139ENST00000533920chr11:567320-567386160.00-69.7965NA
ENSG00000247095hsa-mir-139ENST00000533920chr11:567200-567272152.00-73.2869NA
ENSG00000247095hsa-mir-139ENST00000533920chr11:567782-567846151.00-61.0360NA
ENSG00000247095hsa-mir-139ENST00000533920chr11:567859-567931151.00-63.9669NA
ENSG00000247095hsa-mir-139ENST00000533920chr11:567459-567528145.00-59.8366NA
ENSG00000247095hsa-mir-139ENST00000534540chr11:567635-567701160.00-69.7965NA
ENSG00000247095hsa-mir-139ENST00000534540chr11:567774-567843145.00-59.8366NA

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Variants for MIR210HG

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types
ENSG00000247095MIR210HG,hsa-mir-139,SAMD10CHOL,PAAD,THYM,KIRP,LIHC
ENSG00000247095MIR210HG,hsa-mir-139,TONSLCHOL,PAAD,THYM,KIRP,LIHC
ENSG00000247095MIR210HG,hsa-mir-139,VMP1CHOL,PAAD,THYM,KIRP,LIHC

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000247095.2ENST00000500447.15223375
ENSG00000247095.2ENST00000528245.115918771398
ENSG00000247095.2ENST00000533920.1119300656
ENSG00000247095.2ENST00000534540.11344032