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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000239415

Summary for AP001469.9

check button Gene summary

Gene informationEnsembl ID

ENSG00000239415

Gene symbol

AP001469.9

Gene name
HGNC
Entrez ID
Gene typeantisense
Synonyms
UniProtAcc

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Structure and expression level for AP001469.9

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002394157.365416e+011.404537e+001.270379e-011.105605e+012.050000e-284.890000e-27UPCOAD
ENSG000002394158.144250e+011.254666e+002.497865e-015.022952e+005.090000e-076.910000e-06UPREAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value

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lncRNA-Protein interaction for AP001469.9

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000239415ENST00000447037AP001469.9ENSG00000185658BRWD169.9895.9754Q9NSI6EpiNA
ENSG00000239415ENST00000447037AP001469.9ENSG00000131149GSE157.7696.5432Q14687EpiNA
ENSG00000239415ENST00000447037AP001469.9ENSG00000117625RCOR36.790.5884Q9P2K3EpiNA
ENSG00000239415ENST00000430259AP001469.9ENSG00000185658BRWD187.9697.2437Q9NSI6EpiNA
ENSG00000239415ENST00000430259AP001469.9ENSG00000131149GSE172.7796.046Q14687EpiNA
ENSG00000239415ENST00000430259AP001469.9ENSG00000172273HINFP22.7490.7861Q9BQA5TF,EpiNA
ENSG00000239415ENST00000430259AP001469.9ENSG00000116560SFPQ50.794.9721P23246RBP,EpiNA
ENSG00000239415ENST00000430259AP001469.9ENSG00000173894CBX213.4794.9845Q14781TF,EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000239415ENST00000447037AP001469.9ENSG00000196670ZFP6246.4890.8239Q8NB50TFNA
ENSG00000239415ENST00000447037AP001469.9ENSG00000166432ZMAT129.492.3844Q5H9K5TFNA
ENSG00000239415ENST00000447037AP001469.9ENSG00000167766ZNF8311.190.0662P51522TFNA
ENSG00000239415ENST00000430259AP001469.9ENSG00000135164DMTF192.2190.1391Q9Y222TFNA
ENSG00000239415ENST00000430259AP001469.9ENSG00000166432ZMAT137.6392.6574Q5H9K5TFNA
ENSG00000239415ENST00000430259AP001469.9ENSG00000173894CBX213.4794.6731Q14781TF,EpiNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000239415ENST00000430259AP001469.9ENSG00000004534RBM692.2293.1677P78332RBPNA
ENSG00000239415ENST00000430259AP001469.9ENSG00000116560SFPQ50.794.3992P23246RBP,EpiNA
ENSG00000239415ENST00000430259AP001469.9ENSG00000124193SRSF627.8191.3683Q13247RBPNA
ENSG00000239415ENST00000430259AP001469.9ENSG00000111364DDX559.4495.1135Q8NHQ9RBPNA
ENSG00000239415ENST00000447037AP001469.9ENSG00000004534RBM672.9491.1143P78332RBPNA
ENSG00000239415ENST00000447037AP001469.9ENSG00000163728TTC1471.4991.9121Q96N46RBPNA

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lncRNA-DNA interaction for AP001469.9

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
ZNF30,AGAP6,FAAP100,ATAT1,GLI4,SH2B1,PRR3,UBE2G2,CHTF18,PPOX,N4BP2L2,DMTF1,TAF1D,CSAD,INO80D,NDUFAF6,BIVM,DCAF8,SLX4IP,DDX55,KLHDC4,CCNL2,METTL5,MIX23,CAPN10,CENATAC,OGA,MSANTD2,THOC1,RECQL5,CCDC14,WDR59,TFAP4,ACBD6,TNK2,ZBED5,CENPT,OSGEPL1,TTC14,CCNT2,CFAP410,POGZ,ANAPC7,KAT2A,LTO1,BRWD1,RBM4B,ANKS6,CSTF3,METAP1D,PCNT,C21orf58,RNPS1,CLK2,ZBTB3,ADAT2,RBM25,POLG2,ENDOV,AAAS,THAP9,WDR83,PRPF39,ERMARD,RABL2A,DHPS,SS18L1,RPAIN,PCED1A,ACYP1,HAUS5,CEP43,DYNLT2,CFAP298,ACIN1,DYRK1A,ZC3H8,ANKS3,ARGLU1,YJEFN3,C3orf62,PAXBP1,ZFP62,ALKBH2,FNBP4,KRI1,TIGD1,C12orf73,DONSON,TRIM52,PMS1,ATG14,CLASRP,POGLUT1,STK36,TTC32,TIA1,ZMAT1,ZNF83,GOLGA8B,HEMK1,NSUN6,DCUN1D2,GOLGA8A,C2orf68,SOX12,SETD4,RBM6,GIGYF1,FAM193B,TMCO6,DUSP28,RBM5,NKTR,CRAMP1,LUC7L,ARHGAP33,MBTD1,PNN,COA5,DNASE1,TTLL3,HEXD,ZNF84,KLHL23,LSS,TTC3,WDR27,WDR33,TESMIN,CEP131,HINFP,KHDC4,SLC19A1,CERS5,RSAD1,TSC1,HPS4,PNISR,SFPQ
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.
Only predicted by TDF
DCAF8,CLASRP,POGLUT1,LUC7L,TCTE3,SFPQ,PCNT,TMCO6,HEMK1,C21orf59,RAD9A,C3orf62,TIA1,ING5,STK36,RBM5,ATAT1,KLHDC4,OSGEPL1,ZMAT1,BRWD1,DHPS,HAUS5,RNPS1,KIAA0907,KRI1,TFAP4,C21orf58,MTL5,KAT2A,CEP131,ZNF83,METTL22,SETD4,POGZ,RBM6,ALKBH2,C2orf68,PRPF3,OXLD1,ZNF30,ARGLU1,ERMARD,WDR83,METTL5,MDM4,INO80D,STX16
Exist in public source
NA

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for AP001469.9

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
ACTN4,EHD4,CAP1,ANXA2,CDKN1A
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for AP001469.9

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation
ENSG00000239415ENSG00000137343ATAT1CESC,COAD,LAML,LGG,THYM,UCECCOAD
ENSG00000239415ENSG00000132680KHDC4COAD,LAML,LGG,OV,PCPG,PRAD,READ,UCEC,UCSREAD
ENSG00000239415ENSG00000132749TESMINCOAD,LAML,READ,UCEC,UCSREAD
ENSG00000239415ENSG00000165138ANKS6COAD,LAML,LGG,READ,UCSCOAD,READ
ENSG00000239415ENSG00000166012TAF1DCOAD,LAML,LGG,PCPG,PRADCOAD
ENSG00000239415ENSG00000175265GOLGA8ACOAD,LGG,OV,PRAD,TGCT,UCSCOAD
ENSG00000239415ENSG00000184465WDR27COAD,LAML,LGG,OV,TGCT,UCSCOAD
ENSG00000239415ENSG00000184786DYNLT2COAD,LAML,LGG,THYM,UCEC,UCSCOAD
ENSG00000239415ENSG00000189007ADAT2COAD,LAML,READ,TGCT,THYM,UCEC,UCSCOAD,READ
ENSG00000239415ENSG00000215252GOLGA8BCOAD,LGG,PCPG,PRAD,TGCT,UCSCOAD
ENSG00000239415ENSG00000256525POLG2COAD,LGG,PRAD,READ,THYMREAD
ENSG00000239415ENSG00000173638SLC19A1LGG,OV,PRAD,READ,THYMREAD

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types
ENSG00000239415ENSG00000166432ZMAT1ENSG00000132716DCAF85LAML,LGG,PCPG,PRAD,TGCT
ENSG00000239415ENSG00000167766ZNF83ENSG00000132716DCAF85COAD,OV,PCPG,PRAD,TGCT
ENSG00000239415ENSG00000166432ZMAT1ENSG00000007392LUC7L5LAML,LGG,PCPG,PRAD,TGCT
ENSG00000239415ENSG00000166432ZMAT1ENSG00000185917SETD45LAML,LGG,PCPG,PRAD,TGCT

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000239415ENST00000447037CDKN1AENSG00000124762ENST00000373711-0.1133319-COAD,READ
ENSG00000239415ENST00000430259CDKN1AENSG00000124762ENST00000373711-0.266966-COAD,READ

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000239415.1ENST00000447037.14953202
ENSG00000239415.1ENST00000430259.167562359