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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000237978

Summary for KCNMB2-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000237978

Gene symbol

KCNMB2-AS1

Gene nameKCNMB2 antisense RNA 1
HGNC

51409

Entrez ID
Gene typeantisense
Synonyms03q26.32|KCNMB2-AS1
UniProtAcc

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Structure and expression level for KCNMB2-AS1

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002379781.710805e+021.755521e+003.808055e-014.610020e+004.030000e-063.090000e-05UPBLCA
ENSG000002379781.438536e+026.834541e+001.640675e+004.165688e+003.100000e-054.600270e-04UPCESC
ENSG000002379781.773369e+022.251787e+002.560600e-018.793983e+001.440000e-182.630000e-17UPHNSC
ENSG000002379781.307826e+025.780396e+003.051290e-011.894411e+014.940000e-802.120000e-77UPUCEC
ENSG000002379782.686223e+023.366965e+005.841108e-015.764257e+008.200000e-094.580000e-07UPESCA
ENSG000002379784.932240e+027.452261e+002.203937e-013.381340e+011.250000e-2501.630000e-247UPLUSC
ENSG000002379789.215028e+015.521748e+003.643911e-011.515336e+017.200000e-524.440000e-50UPLUAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002379783.531712e-011.100805e-18UCEC3.802781e-17

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lncRNA-Protein interaction for KCNMB2-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for KCNMB2-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
E2F6,CHEK2,COMMD2,EIF2B5,XXYLT1,CHST14,DNAJC19,TBL1XR1,RPL39L,RYK,WDR53,PARL,ALG1L,CLDND1,YEATS2,C12orf73,NDUFB5,DNAJB11,TARBP2,CEBPZOS,MLF1,BCL7C,DCUN1D1,SLC44A5,TTC30B,WDR72,TMEM41A,NCBP2,UBXN7
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for KCNMB2-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for KCNMB2-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation
ENSG00000237978ENSG00000114503NCBP2BLCA,CESC,ESCA,HNSC,LUAD,LUSC,THYM,UCSLUSC
ENSG00000237978ENSG00000137968SLC44A5BLCA,LUAD,OV,THYM,UCSLUAD
ENSG00000237978ENSG00000139546TARBP2BLCA,CESC,ESCA,HNSC,LUAD,UCSBLCA
ENSG00000237978ENSG00000145191EIF2B5BLCA,ESCA,HNSC,LUAD,LUSC,THYMLUSC
ENSG00000237978ENSG00000205981DNAJC19BLCA,CESC,ESCA,HNSC,LUAD,LUSC,OV,THYM,UCEC,UCSLUSC
ENSG00000237978ENSG00000043093DCUN1D1CESC,ESCA,HNSC,LUAD,LUSC,THYM,UCSLUSC
ENSG00000237978ENSG00000136521NDUFB5CESC,ESCA,HNSC,LUAD,LUSC,OV,UCECLUSC
ENSG00000237978ENSG00000163872YEATS2CESC,ESCA,HNSC,LUSC,THYMESCA,HNSC,LUSC
ENSG00000237978ENSG00000163923RPL39LCESC,ESCA,HNSC,LUAD,LUSC,OV,UCECCESC,ESCA,HNSC,LUAD,LUSC,UCEC
ENSG00000237978ENSG00000189366ALG1LCESC,ESCA,HNSC,LUAD,LUSC,OV,THYMCESC,ESCA,HNSC,LUAD,LUSC
ENSG00000237978ENSG00000080822CLDND1ESCA,HNSC,LUAD,LUSC,THYMLUSC
ENSG00000237978ENSG00000090520DNAJB11ESCA,HNSC,LUAD,LUSC,UCEC,UCSLUSC,UCEC
ENSG00000237978ENSG00000163900TMEM41AESCA,HNSC,LUSC,THYM,UCSLUSC
ENSG00000237978ENSG00000163960UBXN7ESCA,HNSC,LUSC,THYM,UCSLUSC
ENSG00000237978ENSG00000173950XXYLT1ESCA,HNSC,LUAD,LUSC,UCSLUSC
ENSG00000237978ENSG00000175193PARLESCA,HNSC,LUAD,LUSC,OV,UCSLUSC
ENSG00000237978ENSG00000177565TBL1XR1ESCA,HNSC,LUSC,UCEC,UCSLUSC
ENSG00000237978ENSG00000183765CHEK2ESCA,HNSC,LUAD,LUSC,THYMESCA,LUAD,LUSC
ENSG00000237978ENSG00000185798WDR53ESCA,HNSC,LUAD,LUSC,UCSESCA,LUSC
ENSG00000237978ENSG00000166415WDR72HNSC,LUAD,LUSC,OV,THYMLUAD,LUSC

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000237978.4ENST00000437488.45368229
ENSG00000237978.4ENST00000432385.48633272
ENSG00000237978.4ENST00000451742.4732180
ENSG00000237978.4ENST00000425330.18332069
ENSG00000237978.4ENST00000421498.1716221