lncRNAfunc Logo

Home

Download

Statistics

Landscape

Help

Contact

Center for Computational Systems Medicine
leaf

lncRNA summary

leaf

lncRNA structure and expression level

leaf

lncRNA-Protein interaction

leaf

lncRNA-DNA interaction

leaf

lncRNA-RNA interaction

leaf

Variants in lncRNA

leaf

lncRNAs regulate the target genes through functioning as enhancers

leaf

lncRNAs regulate the target genes through recruiting transcript factors

leaf

lncRNAs regulate the alternative splicing events through interacting with splicing factor

leaf

lncRNAs regulate mRNA through targeting the 3'-UTR region

leaf

lncRNAs regulate mRNA by competing with miRNA

leaf

lncRNA coding potential

lncRNA: ENSG00000235280

Summary for MCF2L-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000235280

Gene symbol

MCF2L-AS1

Gene nameMCF2L antisense RNA 1
HGNC

39825

Entrez ID
Gene typeantisense
SynonymsMCF2L-AS1|13q34
UniProtAcc

Top

Structure and expression level for MCF2L-AS1

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002352803.295589e+021.892679e+002.098864e-019.017635e+001.920000e-192.980000e-18UPKICH
ENSG000002352801.177567e+021.518292e+002.302589e-016.593848e+004.290000e-113.040000e-10UPUCEC
ENSG000002352809.812439e+013.561159e+005.538610e-016.429698e+001.280000e-101.090000e-08UPPCPG
ENSG000002352801.645531e+021.492068e+001.786280e-018.352933e+006.660000e-177.060000e-16UPCOAD
ENSG000002352801.918661e+021.161517e+002.477578e-014.688113e+002.760000e-061.660000e-05UPSTAD
ENSG000002352802.067249e+021.590260e+003.368529e-014.720934e+002.350000e-062.710000e-05UPREAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002352804.715829e-011.075169e-03CHOL1.812058e-03
ENSG000002352804.141999e-015.457566e-05KICH9.775108e-05

Top

lncRNA-Protein interaction for MCF2L-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000235280ENST00000446789MCF2L-AS1ENSG00000139746RBM2679.1590.6022Q5T8P6RBPNA

Top

lncRNA-DNA interaction for MCF2L-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

Top

lncRNA-RNA interaction for MCF2L-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
S100A16,RARG,SSPN,FRMD6,UACA,ANTXR2,MACF1,SH3GLB1,RAI14,QKI,PLS1,BIRC2,PPP4R1,ELL2,FEZ2,NTAN1,NEK7,IL4R,BMP1,SPATS2L,FLNA,ARSB,MYH9,SNX29,APAF1,ZEB2,TNFRSF1A,PLSCR4,TPM4,AIDA,PDLIM5,TIPARP,YAP1,WWTR1,SP100,IL6ST,RCAN1,ITGA9,CDC27,CAST,EMP3,IL1R1,SEPTIN11,TPM3,MAP4,MORF4L1,ADGRE5,CLIP1,CORO1C,RNF19B,ITGB1,ANXA2,EDEM1,MAF,BZW1,SEC23A,GIT2,GNAI2,EPS15,CDV3,ARFGAP3,CAP1,TUBB6
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000235280ENST00000446789exon_skip_44998chr10:110132304-110132400-8.89-0.1252ADD3ENST00000356080In-frame
ENSG00000235280ENST00000446789exon_skip_60345chr11:63903985-63904147-27.57-0.1767MARK2ENST00000402010In-frame
ENSG00000235280ENST00000446789exon_skip_98384chr12:124327408-124327633-29.12-0.1300NCOR2ENST00000405201In-frame
ENSG00000235280ENST00000446789exon_skip_146683chr16:85780378-85780473-22.34-0.2660EMC8ENST00000253457Frame-shift
ENSG00000235280ENST00000446789exon_skip_384879chr3:52554723-52554879-32.65-0.2148PBRM1ENST00000296302In-frame
ENSG00000235280ENST00000446789exon_skip_423795chr4:55888887-55888932-7.91-0.2260EXOC1ENST00000346134,ENST00000381295In-frame
ENSG00000235280ENST00000446789exon_skip_461111chr6:90544551-90544632-13.84-0.2197MAP3K7ENST00000369329In-frame
ENSG00000235280ENST00000446789exon_skip_386291chr3:108050577-108050602-7.07-0.5892CD47ENST00000361309Frame-shift
ENSG00000235280ENST00000446789exon_skip_40119chr10:24494499-24494604-12.45-0.1399KIAA1217ENST00000376454In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000235280ENST00000446789exon_skip_21610chr1:9737497-9737554-7.85-0.3413CLSTN1ENST00000377298In-frame
ENSG00000235280ENST00000446789exon_skip_21628chr1:9756480-9756510-7.10-0.3227CLSTN1ENST00000377298In-frame
ENSG00000235280ENST00000446789exon_skip_30360chr1:150842423-150842468-8.37-0.3219ARNTENST00000358595In-frame
ENSG00000235280ENST00000446789exon_skip_33516chr1:156938417-156938513-17.60-0.2316ARHGEF11ENST00000361409In-frame
ENSG00000235280ENST00000446789exon_skip_104174chr13:79353152-79353224-8.33-0.1772RBM26ENST00000438737In-frame
ENSG00000235280ENST00000446789exon_skip_287874chr17:29085603-29085648-7.10-0.4733MYO18AENST00000527372In-frame
ENSG00000235280ENST00000446789exon_skip_361434chr21:25997359-25997416-10.18-0.2166APPENST00000346798In-frame
ENSG00000235280ENST00000446789exon_skip_368285chr22:29329711-29329720-2.66-1.3300AP1B1ENST00000357586,ENST00000405198In-frame
ENSG00000235280ENST00000446789exon_skip_382356chr3:37091466-37091538-7.64-0.1592LRRFIP2ENST00000336686In-frame
ENSG00000235280ENST00000446789exon_skip_451515chr6:41080810-41080897-14.34-0.1938NFYAENST00000341376In-frame
ENSG00000235280ENST00000446789exon_skip_106783chr14:55673171-55673255-6.10-0.1070KTN1ENST00000395314In-frame
ENSG00000235280ENST00000446789exon_skip_96112chr12:109945259-109945349-14.42-0.1897GIT2ENST00000355312In-frame
ENSG00000235280ENST00000446789exon_skip_376144chr3:100311832-100311877-5.50-0.2292TBC1D23ENST00000394144In-frame

check buttonlncRNA targets by miRNA.
lncRNA targets by miRNA
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source
ENSG00000235280hsa-mir-145ENST00000446789chr13:112968033-112968120168.00-68.2280NA
ENSG00000235280hsa-mir-145ENST00000446789chr13:112967948-112968033165.00-80.1588NA
ENSG00000235280hsa-mir-145ENST00000446789chr13:112967724-112967832159.00-72.72107NA
ENSG00000235280hsa-mir-145ENST00000446789chr13:112967844-112967926148.00-64.3886NA

Top

Variants for MCF2L-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

Top

lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

Top

lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

Top

lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

Top

lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000235280ENST00000446789WWTR1ENSG00000018408ENST00000467467-0.147434-KICH,UCEC,COAD,READ
ENSG00000235280ENST00000446789ARSBENSG00000113273ENST00000565165-0.2364499-KICH
ENSG00000235280ENST00000446789PLSCR4ENSG00000114698ENST00000446574-0.110817-KICH,UCEC,PCPG,COAD,READ
ENSG00000235280ENST00000446789PLSCR4ENSG00000114698ENST00000493382-0.1167217-KICH,UCEC,PCPG,COAD,READ
ENSG00000235280ENST00000446789ADGRE5ENSG00000123146ENST00000358600-0.16401-KICH,UCEC
ENSG00000235280ENST00000446789ITGB1ENSG00000150093ENST00000494395-0.101024-KICH
ENSG00000235280ENST00000446789TPM4ENSG00000167460ENST00000592822-0.224991-KICH
ENSG00000235280ENST00000446789S100A16ENSG00000188643ENST00000368705-0.16211-KICH
ENSG00000235280ENST00000446789ARFGAP3ENSG00000242247ENST00000437119-0.128075-PCPG
ENSG00000235280ENST00000446789FRMD6ENSG00000139926ENST00000557405-0.156955-UCEC,PCPG,STAD,READ
ENSG00000235280ENST00000446789FRMD6ENSG00000139926ENST00000555197-0.1628419-UCEC,PCPG,STAD,READ
ENSG00000235280ENST00000446789ITGA9ENSG00000144668ENST00000422441-0.291367-UCEC,PCPG,STAD
ENSG00000235280ENST00000446789PLS1ENSG00000120756ENST00000497002-0.2070467-KICH,COAD,READ
ENSG00000235280ENST00000446789BZW1ENSG00000082153ENST00000452790-0.187990-PCPG
ENSG00000235280ENST00000446789SSPNENSG00000123096ENST00000540266-0.5086262-KICH,UCEC,COAD,STAD,READ
ENSG00000235280ENST00000446789SSPNENSG00000123096ENST00000535504-0.1776508-KICH,UCEC,COAD,STAD,READ
ENSG00000235280ENST00000446789IL6STENSG00000134352ENST00000502326-0.4721539-UCEC,COAD,READ
ENSG00000235280ENST00000446789UACAENSG00000137831ENST00000560441-0.1361118-KICH
ENSG00000235280ENST00000446789UACAENSG00000137831ENST00000539319-0.4583284-KICH
ENSG00000235280ENST00000446789NEK7ENSG00000151414ENST00000367383-0.1446536-UCEC,PCPG,READ
ENSG00000235280ENST00000446789RCAN1ENSG00000159200ENST00000492600-0.14381-KICH,COAD,READ
ENSG00000235280ENST00000446789ANTXR2ENSG00000163297ENST00000404191-0.14995-KICH,UCEC,COAD,STAD,READ
ENSG00000235280ENST00000446789ANTXR2ENSG00000163297ENST00000346652-0.5265100-KICH,UCEC,COAD,STAD,READ
ENSG00000235280ENST00000446789FEZ2ENSG00000171055ENST00000414288-0.158374-UCEC,READ
ENSG00000235280ENST00000446789FEZ2ENSG00000171055ENST00000432869-0.10111-UCEC,READ
ENSG00000235280ENST00000446789IL1R1ENSG00000115594ENST00000409329-0.1710102-KICH,PCPG
ENSG00000235280ENST00000446789IL1R1ENSG00000115594ENST00000409288-0.131052-KICH,PCPG
ENSG00000235280ENST00000446789IL1R1ENSG00000115594ENST00000422532-0.17721-KICH,PCPG
ENSG00000235280ENST00000446789TNFRSF1AENSG00000067182ENST00000534885-0.10651-PCPG
ENSG00000235280ENST00000446789TNFRSF1AENSG00000067182ENST00000543995-0.10651-PCPG
ENSG00000235280ENST00000446789TNFRSF1AENSG00000067182ENST00000540022-0.378890-PCPG
ENSG00000235280ENST00000446789TNFRSF1AENSG00000067182ENST00000543048-0.113447-PCPG
ENSG00000235280ENST00000446789YAP1ENSG00000137693ENST00000531439-0.445079-UCEC,PCPG
ENSG00000235280ENST00000446789SPATS2LENSG00000196141ENST00000451764-0.22557-KICH
ENSG00000235280ENST00000446789SPATS2LENSG00000196141ENST00000409151-0.22551-KICH
ENSG00000235280ENST00000446789FLNAENSG00000196924ENST00000369850-0.14495-KICH,UCEC,COAD,STAD,READ
ENSG00000235280ENST00000446789FLNAENSG00000196924ENST00000344736-0.3058100-KICH,UCEC,COAD,STAD,READ

Top

lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

Top

lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000235280.2ENST00000446789.2142902474