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lncRNA: ENSG00000235245

Summary for RP11-122K13.12

Gene summary

Gene information	Ensembl ID	ENSG00000235245
	Gene symbol	RP11-122K13.12
	Gene name
	HGNC
	Entrez ID
	Gene type	antisense
	Synonyms
	UniProtAcc

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Structure and expression level for RP11-122K13.12

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000235245	6.919923e+01	1.721656e+00	1.419308e-01	1.213025e+01	7.300000e-34	8.960000e-33	UP	KIRC

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000235245	5.947998e-01	1.641387e-05	CHOL	9.125258e-05

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lncRNA-Protein interaction for RP11-122K13.12

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000235245	ENST00000424450	RP11-122K13.12	ENSG00000131149	GSE1	6.61	90.0882	Q14687	Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

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lncRNA-DNA interaction for RP11-122K13.12

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-122K13.12

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

RPS10,SMIM12,TTC1,DNAJC8,DDT,RNF181,GET3,LAMTOR2,PSMB2,NDUFA8,OSTC,MRPL51,ATOX1,MIX23,NDUFB2,HPF1,ATP5PO,ZNHIT1,PPIH,ARPC4,CLPP,RPS27L,MRPL27,SDHAF2,HIGD1A,RPL35,DRG1,POLR2J,MRPS33,SLIRP,GTF2H5,COX6B1,PSMA4,ROMO1,DHRS4L2,NDUFB10,NDUFB9,ATP5PD,COPS9,COX14,NUDC,BOLA3,PARK7,MRPL33,NDUFA12,ATP5PB,ATP5MK,DYNLL1,NDUFC1,MCTS1,FRG1,UQCR11,NDUFB4,COX17,MRPL47,TXN2,UQCRQ,DECR1,PRDX5,EMC3,GSTO1,HSPE1,ZBTB8OS,CYCS,TXNDC17,SURF2,ATP5MJ,NDUFAF8,NDUFB11,NDUFS3,SSBP1,LSM3,SNRPC,NAXE,PSMA2,OAZ1,BANF1,MICOS10,STX8,DBI,HIKESHI,RBIS,ATP5PF,UBE2F,MYL6,COX8A,PSMB7,PSMB1,TMEM126A,COX7C,NDUFAB1,NDUFB3,COX5A,COX7A2,EIF3K,FAM162A,MRPS15,PSMB6,PPIA,BUD31,NDUFC2,SPCS1,NDUFA3,NDUFA6,NDUFA1,SEC61B,TBCA

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

ORF mutation

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000235245	ENST00000424450	exon_skip_370518	chr22:50247691-50247776	-15.14	-0.2019	HDAC10	ENST00000216271	Frame-shift
ENSG00000235245	ENST00000424450	exon_skip_374551	chr3:50100531-50100605	-9.80	-0.1690	RBM5	ENST00000347869	Frame-shift
ENSG00000235245	ENST00000424450	exon_skip_382458	chr3:38131595-38131638	-8.83	-0.4205	ACAA1	ENST00000333167	Frame-shift
ENSG00000235245	ENST00000424450	exon_skip_290158	chr17:42953723-42953778	-6.58	-0.1343	AARSD1	ENST00000427569	Frame-shift
ENSG00000235245	ENST00000424450	exon_skip_374497	chr3:49999439-49999513	-14.14	-0.1911	RBM6	ENST00000266022	Frame-shift
ENSG00000235245	ENST00000424450	exon_skip_470226	chr7:103307595-103307708	-13.75	-0.1403	PMPCB	ENST00000249269	Frame-shift
ENSG00000235245	ENST00000424450	exon_skip_340759	chr2:85552415-85552567	-16.46	-0.1097	GGCX	ENST00000233838	Frame-shift

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for RP11-122K13.12

RNA A-to-I editing events in lncRNA.

LncRNAediting ID	LncRNA Ensembl ID	Chromosome	Editing Position	Strand	Gene Type	Gene Name	Transcript ID	Transcript Type	Transcript Name
LncEditing_238549	ENSG00000235245.1	chr10	133295281	-	antisense	RP11-122K13.12	ENST00000424450.1	antisense	RP11-122K13.12-001
LncEditing_238553	ENSG00000235245.1	chr10	133295347	-	antisense	RP11-122K13.12	ENST00000424450.1	antisense	RP11-122K13.12-001
LncEditing_238557	ENSG00000235245.1	chr10	133295390	-	antisense	RP11-122K13.12	ENST00000424450.1	antisense	RP11-122K13.12-001
LncEditing_238559	ENSG00000235245.1	chr10	133295400	-	antisense	RP11-122K13.12	ENST00000424450.1	antisense	RP11-122K13.12-001
LncEditing_238561	ENSG00000235245.1	chr10	133295403	-	antisense	RP11-122K13.12	ENST00000424450.1	antisense	RP11-122K13.12-001
LncEditing_238563	ENSG00000235245.1	chr10	133295433	-	antisense	RP11-122K13.12	ENST00000424450.1	antisense	RP11-122K13.12-001
LncEditing_238564	ENSG00000235245.1	chr10	133295441	-	antisense	RP11-122K13.12	ENST00000424450.1	antisense	RP11-122K13.12-001

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID	LncRNA Index	Cancer Type	Chr_Postion_Strand	AVE1	AVE2	log2FC	W-value	P-value	Adjc.p-value	Change
ENSG00000235245	LncEditing_238559	KIRC	chr10_133295400_-	4.410473e+00	1.857222e+00	8.014185e-01	9.856232e+00	6.442170e-23	1.848082e-22	UP
ENSG00000235245	LncEditing_238549	LAML	chr10_133295281_-	1.309454e+01	1.013414e+01	2.704589e+00	3.395428e+00	6.852137e-04	9.208258e-04	UP
ENSG00000235245	LncEditing_238553	LAML	chr10_133295347_-	1.624353e+01	1.016843e+01	1.479796e+00	4.549869e+00	5.367939e-06	1.086788e-05	UP
ENSG00000235245	LncEditing_238557	LAML	chr10_133295390_-	1.469343e+01	9.475247e+00	1.579940e+00	5.970081e+00	2.371364e-09	9.827632e-09	UP
ENSG00000235245	LncEditing_238559	LAML	chr10_133295400_-	1.469009e+01	9.895725e+00	1.754490e+00	4.748765e+00	2.046625e-06	4.541663e-06	UP
ENSG00000235245	LncEditing_238564	LAML	chr10_133295441_-	1.286577e+01	9.894219e+00	2.639356e+00	3.611346e+00	3.046114e-04	4.349076e-04	UP
ENSG00000235245	LncEditing_238557	CHOL	chr10_133295390_-	3.392489e+00	2.334624e+00	1.854759e+00	2.310018e+00	2.088718e-02	2.612193e-02	UP
ENSG00000235245	LncEditing_238557	OV	chr10_133295390_-	2.571090e+00	1.384500e+00	1.119802e+00	8.048628e+00	8.372706e-16	2.495528e-15	UP
ENSG00000235245	LncEditing_238559	OV	chr10_133295400_-	2.420585e+00	1.396440e+00	1.260077e+00	7.306780e+00	2.736195e-13	6.401861e-13	UP
ENSG00000235245	LncEditing_238561	OV	chr10_133295403_-	2.653046e+00	1.398164e+00	1.082114e+00	7.686022e+00	1.517803e-14	4.057034e-14	UP
ENSG00000235245	LncEditing_238557	STAD	chr10_133295390_-	2.831068e+00	1.483310e+00	1.072356e+00	9.080730e+00	1.078494e-19	4.550714e-19	UP
ENSG00000235245	LncEditing_238559	STAD	chr10_133295400_-	2.740868e+00	1.499593e+00	1.149344e+00	8.668501e+00	4.378469e-18	1.531848e-17	UP
ENSG00000235245	LncEditing_238561	STAD	chr10_133295403_-	2.956813e+00	1.551405e+00	1.074729e+00	7.664444e+00	1.796071e-14	4.108584e-14	UP
ENSG00000235245	LncEditing_238549	ESCA	chr10_133295281_-	3.176459e+00	2.258212e+00	2.031534e+00	3.366303e+00	7.618303e-04	8.778430e-04	UP
ENSG00000235245	LncEditing_238553	ESCA	chr10_133295347_-	3.312366e+00	2.220006e+00	1.732207e+00	4.397480e+00	1.095150e-05	1.526220e-05	UP
ENSG00000235245	LncEditing_238557	ESCA	chr10_133295390_-	3.132753e+00	1.902590e+00	1.389918e+00	6.701355e+00	2.064952e-11	7.756523e-11	UP
ENSG00000235245	LncEditing_238559	ESCA	chr10_133295400_-	2.943109e+00	1.944957e+00	1.673354e+00	5.709824e+00	1.130930e-08	2.406528e-08	UP
ENSG00000235245	LncEditing_238561	ESCA	chr10_133295403_-	3.136929e+00	2.091821e+00	1.710591e+00	5.226164e+00	1.730632e-07	3.097698e-07	UP
ENSG00000235245	LncEditing_238563	ESCA	chr10_133295433_-	3.540814e+00	2.197923e+00	1.453614e+00	4.733938e+00	2.202047e-06	3.403754e-06	UP
ENSG00000235245	LncEditing_238564	ESCA	chr10_133295441_-	3.194451e+00	1.888940e+00	1.319278e+00	7.143323e+00	9.110132e-13	4.379550e-12	UP

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID	LncRNA Index	Correlation	P-value	Adjc.p-value
ENSG00000235245	LncEditing_238557	-4.823902e-01	2.543347e-04	7.902800e-04
ENSG00000235245	LncEditing_238559	-4.226014e-01	1.057471e-03	2.144590e-03
ENSG00000235245	LncEditing_238561	-3.316489e-01	2.434786e-02	2.583612e-02
ENSG00000235245	LncEditing_238561	-3.305415e-01	2.175554e-02	2.370279e-02
ENSG00000235245	LncEditing_238549	-4.146404e-01	4.915573e-02	4.946168e-02
ENSG00000235245	LncEditing_238561	-4.321356e-01	2.708561e-03	9.737139e-03
ENSG00000235245	LncEditing_238563	-5.130171e-01	1.230171e-02	2.258010e-02
ENSG00000235245	LncEditing_238549	-3.765645e-01	6.457661e-03	1.602777e-02
ENSG00000235245	LncEditing_238553	-4.750761e-01	1.897583e-02	2.857038e-02
ENSG00000235245	LncEditing_238557	-3.827075e-01	7.260939e-03	1.671169e-02
ENSG00000235245	LncEditing_238559	-4.911821e-01	1.497558e-03	8.685838e-03
ENSG00000235245	LncEditing_238564	-3.565545e-01	4.126646e-03	1.271933e-02

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000235245.1	ENST00000424450.1	57	136	309

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential