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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000233101

Summary for HOXB-AS3

check button Gene summary

Gene informationEnsembl ID

ENSG00000233101

Gene symbol

HOXB-AS3

Gene nameHOXB cluster antisense RNA 3
HGNC

40283

Entrez ID

404266

Gene typeantisense
Synonyms17q21.32|HOXB-AS3
UniProtAcc

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Structure and expression level for HOXB-AS3

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002331011.782153e+02-2.372636e+002.203362e-01-1.076825e+014.860000e-274.290000e-26DOWNKIRC
ENSG000002331019.834228e+013.217676e+004.992312e-016.445262e+001.150000e-102.410000e-09UPBLCA
ENSG000002331012.121611e+02-1.835036e+002.862096e-01-6.411512e+001.440000e-101.130000e-09DOWNKIRP
ENSG000002331014.986325e+021.940159e+003.151112e-016.157063e+007.410000e-104.600000e-09UPUCEC
ENSG000002331011.578880e+022.435074e+002.535567e-019.603668e+007.710000e-225.450000e-21UPBRCA

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG00000233101-3.571345e-019.955627e-20KIRC7.284605e-19
ENSG00000233101-3.179963e-012.768426e-08KIRP2.114385e-07

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lncRNA-Protein interaction for HOXB-AS3

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for HOXB-AS3

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
ADAP1,SLC25A29,PGP,ABHD11,TMC4,RBM5,SMDT1,RGL3,CACFD1,TMEM50B,GPR35,CXXC5,CCDC24,CLMN,AGPAT2,GSTO2,NPRL2,SH3GLB2,ABHD14B,AP1M2,SYNE4,P4HTM,SKAP1,LLGL2,PCYT2,DEGS2
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for HOXB-AS3

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for HOXB-AS3

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation
ENSG00000233101ENSG00000073350LLGL2CESC,ESCA,KIRC,KIRP,UCSKIRC
ENSG00000233101ENSG00000129354AP1M2CESC,ESCA,KIRC,KIRP,PAADKIRC,KIRP
ENSG00000233101ENSG00000165959CLMNCESC,ESCA,KIRC,KIRP,UCSKIRC,KIRP
ENSG00000233101ENSG00000168350DEGS2CESC,ESCA,KIRC,OV,PAADKIRC
ENSG00000233101ENSG00000065621GSTO2ESCA,KIRC,KIRP,PAAD,UCSKIRC

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000233101.9ENST00000465846.5100266568
ENSG00000233101.9ENST00000476204.49382363
ENSG00000233101.9ENST00000474040.483175426
ENSG00000233101.9ENST00000467155.5143662231
ENSG00000233101.9ENST00000480872.41053140
ENSG00000233101.9ENST00000429755.793114395
ENSG00000233101.9ENST00000492897.39378359
ENSG00000233101.9ENST00000487849.66732235
ENSG00000233101.9ENST00000481995.4822461
ENSG00000233101.9ENST00000460041.4115105452
ENSG00000233101.9ENST00000474324.1143678247
ENSG00000233101.9ENST00000477144.182103351
ENSG00000233101.9ENST00000466037.5141652227
ENSG00000233101.9ENST00000491264.41133402
ENSG00000233101.9ENST00000494420.111355396