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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000232956

Summary for SNHG15

check button Gene summary

Gene informationEnsembl ID

ENSG00000232956

Gene symbol

SNHG15

Gene namesmall nucleolar RNA host gene 15
HGNC

27797

Entrez ID

285958

Gene typelincRNA
Synonyms07p13|SNHG15
UniProtAcc

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Structure and expression level for SNHG15

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002329566.004585e+021.409138e+002.484218e-015.672361e+001.410000e-081.300000e-07UPCHOL
ENSG000002329561.167890e+031.759107e+001.084942e-011.621383e+014.030000e-591.360000e-57UPKIRC
ENSG000002329569.329212e+021.815172e+001.030279e-011.761825e+011.780000e-694.900000e-67UPCOAD
ENSG000002329561.058392e+031.672129e+001.938179e-018.627319e+006.280000e-188.510000e-16UPREAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002329563.383220e-012.616891e-03ACC1.082851e-02
ENSG000002329564.961157e-015.286058e-04CHOL1.036264e-03
ENSG000002329563.274816e-011.732401e-03KICH2.277839e-03
ENSG000002329564.663728e-013.667895e-34KIRC4.249467e-32
ENSG000002329563.042703e-012.881508e-13PRAD1.505128e-12

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lncRNA-Protein interaction for SNHG15

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000232956ENST00000585030SNHG15ENSG00000116560SFPQ25.9492.5691P23246RBP,EpiNA
ENSG00000232956ENST00000582727SNHG15ENSG00000104885DOT1L48.3791.3912Q8TEK3TF,EpiNA
ENSG00000232956ENST00000582727SNHG15ENSG00000154832CXXC141.7290.3529Q9P0U4TF,EpiNA
ENSG00000232956ENST00000580458SNHG15ENSG00000104885DOT1L32.3791.4581Q8TEK3TF,EpiNA
ENSG00000232956ENST00000579383SNHG15ENSG00000155363MOV1061.3291.5987Q9HCE1RBP,EpiCLIP,iCLIP,PAR-CLIP,GSE70061;High-throughput data combine LncPro prediction
ENSG00000232956ENST00000577700SNHG15ENSG00000155363MOV1061.3190.0578Q9HCE1RBP,EpiCLIP,iCLIP,PAR-CLIP,GSE70061;High-throughput data combine LncPro prediction
ENSG00000232956ENST00000580458SNHG15ENSG00000155363MOV1051.1591.7527Q9HCE1RBP,EpiCLIP,iCLIP,PAR-CLIP,GSE70061;High-throughput data combine LncPro prediction
ENSG00000232956ENST00000585030SNHG15ENSG00000104885DOT1L44.0392.9056Q8TEK3TF,EpiNA
ENSG00000232956ENST00000585030SNHG15ENSG00000172273HINFP12.490.9514Q9BQA5TF,EpiChIP-seq

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000232956ENST00000577700SNHG15ENSG00000077150NFKB266.8990.0717Q00653TFNA
ENSG00000232956ENST00000582727SNHG15ENSG00000130254SAFB261.6994.5007Q14151TF,RBPENCODE,eCLIP
ENSG00000232956ENST00000582727SNHG15ENSG00000104885DOT1L48.3791.5024Q8TEK3TF,EpiNA
ENSG00000232956ENST00000580528SNHG15ENSG00000130254SAFB273.5493.7087Q14151TF,RBPENCODE,eCLIP
ENSG00000232956ENST00000585030SNHG15ENSG00000130254SAFB251.3495.5078Q14151TF,RBPENCODE,eCLIP
ENSG00000232956ENST00000585030SNHG15ENSG00000104885DOT1L44.0393.1223Q8TEK3TF,EpiNA
ENSG00000232956ENST00000585030SNHG15ENSG00000186416NKRF32.6191.9547O15226TFNA
ENSG00000232956ENST00000580458SNHG15ENSG00000104885DOT1L32.3791.6269Q8TEK3TF,EpiNA
ENSG00000232956ENST00000585030SNHG15ENSG00000147789ZNF725.7393.2455P17097TFNA
ENSG00000232956ENST00000585030SNHG15ENSG00000172273HINFP12.490.6709Q9BQA5TF,EpiChIP-seq
ENSG00000232956ENST00000580458SNHG15ENSG00000221944TIGD15.7490.5831Q96MW7TFNA
ENSG00000232956ENST00000580458SNHG15ENSG00000119403PHF192.2890.3Q5T6S3TF,EpiNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000232956ENST00000578968SNHG15ENSG00000013573DDX1159.6490.2548Q96FC9RBPNA
ENSG00000232956ENST00000578968SNHG15ENSG00000165271NOL646.5191.2899Q9H6R4RBPNA
ENSG00000232956ENST00000584327SNHG15ENSG00000148840PPRC111.9991.2156Q5VV67RBPPredict
ENSG00000232956ENST00000578968SNHG15ENSG00000183258DDX4110.9790.2419Q9UJV9RBPNA
ENSG00000232956ENST00000578968SNHG15ENSG00000182810DDX289.3590.5138Q9NUL7RBPNA
ENSG00000232956ENST00000580528SNHG15ENSG00000130254SAFB273.5494.3064Q14151TF,RBPENCODE,eCLIP
ENSG00000232956ENST00000580528SNHG15ENSG00000004534RBM673.4591.8234P78332RBPNA
ENSG00000232956ENST00000585030SNHG15ENSG00000111641NOP259.2892.5306P46087RBPNA
ENSG00000232956ENST00000585030SNHG15ENSG00000130254SAFB251.3495.3225Q14151TF,RBPENCODE,eCLIP
ENSG00000232956ENST00000580458SNHG15ENSG00000155363MOV1051.1591.3905Q9HCE1RBP,EpiCLIP,iCLIP,PAR-CLIP,GSE70061;High-throughput data combine LncPro prediction
ENSG00000232956ENST00000585030SNHG15ENSG00000004534RBM649.5794.9294P78332RBPNA
ENSG00000232956ENST00000580458SNHG15ENSG00000013573DDX1146.9393.7565Q96FC9RBPNA
ENSG00000232956ENST00000580458SNHG15ENSG00000071894CPSF135.3390.7692Q10570RBPPAR-CLIP
ENSG00000232956ENST00000585030SNHG15ENSG00000148840PPRC135.0892.7401Q5VV67RBPPredict
ENSG00000232956ENST00000585030SNHG15ENSG00000265241RBM8A27.190.3225Q9Y5S9RBPNA
ENSG00000232956ENST00000585030SNHG15ENSG00000116560SFPQ25.9492.9474P23246RBP,EpiNA
ENSG00000232956ENST00000580458SNHG15ENSG00000148840PPRC125.7294.387Q5VV67RBPPredict
ENSG00000232956ENST00000580458SNHG15ENSG00000176102CSTF320.3891.7078Q12996RBPNA
ENSG00000232956ENST00000438705SNHG15ENSG00000004534RBM617.7790.2754P78332RBPNA
ENSG00000232956ENST00000580458SNHG15ENSG00000079134THOC117.691.1285Q96FV9RBPNA
ENSG00000232956ENST00000585030SNHG15ENSG00000148296SURF615.6692.6959O75683RBPNA
ENSG00000232956ENST00000580458SNHG15ENSG00000130826DKC112.1290.2783O60832RBPENCODE
ENSG00000232956ENST00000438705SNHG15ENSG00000148840PPRC111.7892.1984Q5VV67RBPPredict
ENSG00000232956ENST00000585030SNHG15ENSG00000184863RBM3311.7392.3733Q96EV2RBPPredict
ENSG00000232956ENST00000585030SNHG15ENSG00000089280FUS11.0893.003P35637RBPHITS-CLIP,CLIP-seq,PAR-CLIP,Scan,pipeline,widely,used,MATCH,algorithm,High-throughput data combine LncPro prediction
ENSG00000232956ENST00000585030SNHG15ENSG00000134597RBMX29.9192.7048Q9Y388RBPNA
ENSG00000232956ENST00000585030SNHG15ENSG00000204356NELFE8.3992.9842P18615RBPNA
ENSG00000232956ENST00000585030SNHG15ENSG00000101361NOP566.0291.5443O00567RBPNA
ENSG00000232956ENST00000577700SNHG15ENSG00000079134THOC174.7190.4549Q96FV9RBPNA
ENSG00000232956ENST00000582727SNHG15ENSG00000130254SAFB261.6994.4929Q14151TF,RBPENCODE,eCLIP
ENSG00000232956ENST00000579383SNHG15ENSG00000155363MOV1061.3291.6962Q9HCE1RBP,EpiCLIP,iCLIP,PAR-CLIP,GSE70061;High-throughput data combine LncPro prediction
ENSG00000232956ENST00000577700SNHG15ENSG00000155363MOV1061.3190.2125Q9HCE1RBP,EpiCLIP,iCLIP,PAR-CLIP,GSE70061;High-throughput data combine LncPro prediction
ENSG00000232956ENST00000582727SNHG15ENSG00000004534RBM661.2592.2823P78332RBPNA
ENSG00000232956ENST00000579383SNHG15ENSG00000013573DDX1154.2694.0886Q96FC9RBPNA
ENSG00000232956ENST00000577700SNHG15ENSG00000162231NXF147.6890.5792Q9UBU9RBPNA
ENSG00000232956ENST00000582727SNHG15ENSG00000162775RBM1545.1391.6988Q96T37RBPENCODE,eCLIP,iCLIP
ENSG00000232956ENST00000579383SNHG15ENSG00000071894CPSF140.6690.8463Q10570RBPPAR-CLIP
ENSG00000232956ENST00000577700SNHG15ENSG00000071894CPSF139.0891.8203Q10570RBPPAR-CLIP
ENSG00000232956ENST00000577700SNHG15ENSG00000091127PUS732.9190.4242Q96PZ0RBPNA
ENSG00000232956ENST00000579383SNHG15ENSG00000176102CSTF330.3390.01799999999999Q12996RBPNA
ENSG00000232956ENST00000577700SNHG15ENSG00000146109ABT125.6890.0772Q9ULW3RBPNA
ENSG00000232956ENST00000582727SNHG15ENSG00000184863RBM3318.0690.9653Q96EV2RBPPredict
ENSG00000232956ENST00000582727SNHG15ENSG00000204356NELFE9.593.203P18615RBPNA

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lncRNA-DNA interaction for SNHG15

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for SNHG15

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
SMAD1,BBX,NFIC,IRF2,GTF2I,STAU1,NR2C2,RBM41,KLF13,KLF7,G3BP2,FOXN3
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000232956ENST00000580528exon_skip_446627chr5:177491806-177491925-29.75-0.2755PDLIM7ENST00000355841Frame-shift
ENSG00000232956ENST00000580528exon_skip_462673chr6:138926400-138926481-10.06-0.1501REPS1ENST00000450536In-frame
ENSG00000232956ENST00000584686exon_skip_17679chr1:211312719-211312961-16.93-0.1085RCOR3ENST00000367005Frame-shift
ENSG00000232956ENST00000580528exon_skip_44998chr10:110132304-110132400-15.00-0.1667ADD3ENST00000356080In-frame
ENSG00000232956ENST00000580528exon_skip_48713chr10:34336198-34336243-10.10-0.3061PARD3ENST00000374789In-frame
ENSG00000232956ENST00000580528exon_skip_106758chr14:55663954-55664041-12.52-0.1527KTN1ENST00000395314In-frame
ENSG00000232956ENST00000580528exon_skip_499771chr9:128592982-128593042-13.61-0.2475SPTAN1ENST00000372731In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000232956ENST00000580528exon_skip_30682chr1:151310210-151310255-10.49-0.3885PI4KBENST00000368873In-frame
ENSG00000232956ENST00000580528exon_skip_43507chr10:84499874-84499959-12.91-0.1699CCSER2ENST00000224756Frame-shift
ENSG00000232956ENST00000580528exon_skip_287874chr17:29085603-29085648-6.57-0.1776MYO18AENST00000527372In-frame
ENSG00000232956ENST00000580528exon_skip_301267chr19:6746028-6746196-23.07-0.1488TRIP10ENST00000313244In-frame
ENSG00000232956ENST00000580528exon_skip_353131chr20:58669290-58669453-25.37-0.1879STX16ENST00000371141Frame-shift
ENSG00000232956ENST00000580528exon_skip_371367chr3:9697710-9697866-21.47-0.1789MTMR14ENST00000296003In-frame
ENSG00000232956ENST00000580528exon_skip_380242chr3:186784961-186785101-14.62-0.2707EIF4A2ENST00000323963Frame-shift
ENSG00000232956ENST00000580528exon_skip_445390chr5:150403120-150403312-25.91-0.1619CD74ENST00000009530In-frame
ENSG00000232956ENST00000580528exon_skip_514339chrX:23713134-23713208-8.55-0.1171ACOT9ENST00000336430Frame-shift
ENSG00000232956ENST00000580528exon_skip_5818chr1:45568484-45568684-20.88-0.1055AKR1A1ENST00000351829,ENST00000372070Frame-shift
ENSG00000232956ENST00000580528exon_skip_52891chr10:98429790-98429889-18.04-0.1940HPS1ENST00000325103,ENST00000361490In-frame
ENSG00000232956ENST00000580528exon_skip_60654chr11:64288064-64288214-23.69-0.1601GPR137ENST00000313074In-frame
ENSG00000232956ENST00000580528exon_skip_75223chr11:72012400-72012442-8.10-0.3522NUMA1ENST00000393695In-frame
ENSG00000232956ENST00000580528exon_skip_83512chr12:53505134-53505262-20.00-0.2000TARBP2ENST00000266987Frame-shift
ENSG00000232956ENST00000580528exon_skip_89597chr12:6672349-6672532-27.30-0.1706ZNF384ENST00000361959,ENST00000396801In-frame
ENSG00000232956ENST00000582727exon_skip_123601chr15:74897010-74897219-19.22-0.1074MPIENST00000352410Frame-shift
ENSG00000232956ENST00000580528exon_skip_123726chr15:75339701-75339878-24.92-0.1743COMMD4ENST00000267935In-frame
ENSG00000232956ENST00000580528exon_skip_140339chr16:635611-635774-26.71-0.1746METTL26ENST00000301686Frame-shift
ENSG00000232956ENST00000580528exon_skip_153767chr17:48057031-48057121-14.80-0.1827NFE2L1ENST00000362042In-frame
ENSG00000232956ENST00000580528exon_skip_305660chr19:35269802-35270003-39.40-0.2478USF2ENST00000222305In-frame
ENSG00000232956ENST00000580528exon_skip_307316chr19:40622949-40623021-16.07-0.2232LTBP4ENST00000308370In-frame
ENSG00000232956ENST00000580528exon_skip_382458chr3:38131595-38131638-6.66-0.2562ACAA1ENST00000333167Frame-shift
ENSG00000232956ENST00000580528exon_skip_446770chr5:178215275-178215430-20.34-0.1485PHYKPLENST00000308158Frame-shift
ENSG00000232956ENST00000580528exon_skip_507092chr9:127732563-127732691-24.46-0.1941TOR2AENST00000373284Frame-shift
ENSG00000232956ENST00000580528exon_skip_11029chr1:154989559-154989707-16.55-0.2018FLAD1ENST00000292180Frame-shift
ENSG00000232956ENST00000582727exon_skip_38175chr1:234398381-234398553-15.91-0.1020TARBP1ENST00000040877Frame-shift
ENSG00000232956ENST00000580528exon_skip_128982chr15:72250844-72250954-18.82-0.1810PARP6ENST00000287196,ENST00000569795Frame-shift
ENSG00000232956ENST00000580528exon_skip_290158chr17:42953723-42953778-8.31-0.1731AARSD1ENST00000427569Frame-shift
ENSG00000232956ENST00000438705exon_skip_356108chr20:34740362-34743341-45.59-0.1002NCOA6ENST00000359003,ENST00000374796In-frame
ENSG00000232956ENST00000580528exon_skip_370518chr22:50247691-50247776-15.05-0.2150HDAC10ENST00000216271Frame-shift
ENSG00000232956ENST00000580528exon_skip_470226chr7:103307595-103307708-11.65-0.1120PMPCBENST00000249269Frame-shift
ENSG00000232956ENST00000438705exon_skip_370501chr22:50220250-50221874-49.89-0.1008TUBGCP6ENST00000248846Frame-shift
ENSG00000232956ENST00000580528exon_skip_377198chr3:123130479-123130616-15.52-0.1398PDIA5ENST00000316218Frame-shift
ENSG00000232956ENST00000580528exon_skip_446758chr5:178212972-178213103-18.31-0.1398PHYKPLENST00000308158Frame-shift
ENSG00000232956ENST00000438705exon_skip_6457chr1:52083339-52083541-14.46-0.1555BTF3L4ENST00000313334Frame-shift
ENSG00000232956ENST00000580528exon_skip_84383chr12:57093406-57093598-25.39-0.1923NAB2ENST00000300131In-frame
ENSG00000232956ENST00000580528exon_skip_152672chr17:42540949-42541206-27.88-0.1181NAGLUENST00000225927Frame-shift
ENSG00000232956ENST00000580528exon_skip_303345chr19:17227839-17228005-26.56-0.1857OCEL1ENST00000215061Frame-shift
ENSG00000232956ENST00000580528exon_skip_116158chr14:102954197-102954275-18.97-0.2710CDC42BPBENST00000361246In-frame
ENSG00000232956ENST00000584686exon_skip_347925chr2:241099395-241099894-24.69-0.1193MTERF4ENST00000391980Frame-shift
ENSG00000232956ENST00000580528exon_skip_367762chr22:21629009-21629187-36.44-0.2292YDJCENST00000292778Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for SNHG15

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000232956.7ENST00000577700.413317191318
ENSG00000232956.7ENST00000578968.410924192748
ENSG00000232956.7ENST00000579383.419865660
ENSG00000232956.7ENST00000585030.4661992
ENSG00000232956.7ENST00000580458.4104630316
ENSG00000232956.7ENST00000438705.3672022
ENSG00000232956.7ENST00000584327.45536203
ENSG00000232956.7ENST00000582727.1692071
ENSG00000232956.7ENST00000584686.1109435764
ENSG00000232956.7ENST00000580528.147371514