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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000232533

Summary for AC093673.5

check button Gene summary

Gene informationEnsembl ID

ENSG00000232533

Gene symbol

AC093673.5

Gene name
HGNC
Entrez ID
Gene typeantisense
Synonyms
UniProtAcc

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Structure and expression level for AC093673.5

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002325338.202449e+021.489975e+003.577061e-014.165361e+003.110000e-051.766580e-04UPGBM
ENSG000002325333.617254e+02-1.972855e+004.622664e-01-4.267789e+001.970000e-053.161620e-04DOWNCESC
ENSG000002325337.851481e+021.574949e+001.528090e-011.030665e+016.580000e-252.640000e-23UPKIRP
ENSG000002325332.101256e+02-1.246684e+001.380116e-01-9.033185e+001.670000e-192.610000e-18DOWNUCEC
ENSG000002325332.971454e+021.030093e+002.897701e-013.554863e+003.781760e-043.677805e-03UPESCA

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002325334.065536e-015.583018e-03CHOL7.157497e-03
ENSG00000232533-4.018391e-019.492244e-05KICH1.610684e-04
ENSG00000232533-3.022091e-017.320763e-14UCEC5.199794e-13

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lncRNA-Protein interaction for AC093673.5

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000232533ENST00000429630AC093673.5ENSG00000106624AEBP148.7191.0681Q8IUX7TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for AC093673.5

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for AC093673.5

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
CNOT1,ASB8,NF1,RALGPS1,PBLD,CMTM4,ZFP14,HACD3,RFX7,NT5C2,ZMYND11,TCF20,DNAJC16,STX17,EPB41,UBR1,PI4KA,LRBA,UBXN7,KIAA1109,PTPN11,KAT6B,TBC1D15,ZNF17,SMG1,MANEA,PBRM1,ERBIN,PUM1,NR2C2,SEC24B,AP1AR,L2HGDH,KMT2D,PIK3C3,NBR1,PHKB,PDPK1,RAPGEF2,C5orf24,MFSD6,ACBD5,MON2,CEP120,PHF3,PMS2,BBX,CPEB4,STRN,TP53BP1,WDR48,PTPN4,DDI2,ACO2,PPIP5K2,TTC3,LYRM7,ABRAXAS1,CLCN3,CIPC,RAD50,BCKDHA,TRPM7,BPTF,ARHGAP5,ITSN2,ASXL2,THAP6,RNF169,MAST3,USP30,KLHL24,FRYL,BAZ2A,CEP350,PIKFYVE,MKRN2,TNKS,SATB1,KBTBD4,CERT1,WDR7,USP46,SMG6,PHC3,MBD5,TMLHE,KIAA0232,DDB1,SIK3,ST13,SYNJ1,PPARA,GFM2,GPATCH8,GTF2A1,ALDH5A1,MPHOSPH8,REST,SMAD5,CNOT6L,HBP1,CSNK1A1,LARS2,CDC23,GOSR1,HUWE1,ATP8A1,HEATR5B,WAC,ACADM,PPM1A,BIRC6,POLK,AFF1,MECP2,GCC2,CHD6,SLC25A30,TLK1,BDP1,SYNRG,TMEM135,AKAP1,CCDC186,KLHL23,SPG11,HDHD2,NEMF,ZHX1,FYCO1,RPRD1A,GCFC2,LANCL1,RALGAPA1,NDUFS1,NSD1,GRAMD1B,SCAF11
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000232533ENST00000429630exon_skip_287874chr17:29085603-29085648-9.01-0.2371MYO18AENST00000527372In-frame
ENSG00000232533ENST00000429630exon_skip_470719chr7:117134123-117134192-7.73-0.2274ST7ENST00000265437In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000232533ENST00000429630exon_skip_153096chr17:44074968-44075087-17.85-0.1750G6PC3ENST00000269097Frame-shift
ENSG00000232533ENST00000429630exon_skip_299306chr18:50274185-50274353-29.98-0.1972MBD1ENST00000269468,ENST00000382948,ENST00000591416In-frame
ENSG00000232533ENST00000429630exon_skip_95500chr12:96003837-96003920-8.52-0.1217LTA4HENST00000228740Frame-shift

check buttonlncRNA targets by miRNA.
lncRNA targets by miRNA
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source
ENSG00000232533hsa-mir-874ENST00000429630chr7:143379730-143379810174.00-88.4579NA
ENSG00000232533hsa-mir-874ENST00000429630chr7:143379878-143379946155.00-70.9376NA
ENSG00000232533hsa-mir-874ENST00000429630chr7:143379961-143380043147.00-72.9577NA
ENSG00000232533hsa-mir-874ENST00000429630chr7:143380205-143380287140.00-61.1382NA

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Variants for AC093673.5

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000232533ENST00000429630L2HGDHENSG00000087299ENST00000261699-0.1750226CESCKIRP
ENSG00000232533ENST00000429630L2HGDHENSG00000087299ENST00000555423-0.2164297CESCKIRP
ENSG00000232533ENST00000429630ACO2ENSG00000100412ENST00000216254-0.13201-GBM,ESCA
ENSG00000232533ENST00000429630ACO2ENSG00000100412ENST00000396512-0.13201-GBM,ESCA
ENSG00000232533ENST00000429630PBLDENSG00000108187ENST00000468798-0.14171-KIRP,ESCA
ENSG00000232533ENST00000429630ACADMENSG00000117054ENST00000420607-0.162581-KIRP
ENSG00000232533ENST00000429630ACADMENSG00000117054ENST00000528016-0.102422-KIRP
ENSG00000232533ENST00000429630GRAMD1BENSG00000023171ENST00000456860-0.314448-GBM,KIRP
ENSG00000232533ENST00000429630GRAMD1BENSG00000023171ENST00000322282-0.3430148-GBM,KIRP
ENSG00000232533ENST00000429630MPHOSPH8ENSG00000196199ENST00000414242-0.105867-GBM
ENSG00000232533ENST00000429630ZMYND11ENSG00000015171ENST00000509513-0.134134-GBM
ENSG00000232533ENST00000429630ZMYND11ENSG00000015171ENST00000602682-0.163250-GBM
ENSG00000232533ENST00000429630ZMYND11ENSG00000015171ENST00000558098-0.134134-GBM
ENSG00000232533ENST00000429630PTPN4ENSG00000088179ENST00000431283-0.4170313-GBM,KIRP
ENSG00000232533ENST00000429630PTPN4ENSG00000088179ENST00000441089-1.3100223-GBM,KIRP
ENSG00000232533ENST00000429630WACENSG00000095787ENST00000428935-0.13221-GBM
ENSG00000232533ENST00000429630MAST3ENSG00000099308ENST00000609494-0.212354-GBM
ENSG00000232533ENST00000429630RAPGEF2ENSG00000109756ENST00000512056-0.1080434-GBM
ENSG00000232533ENST00000429630STRNENSG00000115808ENST00000379213-0.1811506-GBM
ENSG00000232533ENST00000429630ATP8A1ENSG00000124406ENST00000515872-0.2932600-GBM,ESCA
ENSG00000232533ENST00000429630RALGPS1ENSG00000136828ENST00000394022-0.11294-GBM
ENSG00000232533ENST00000429630RALGPS1ENSG00000136828ENST00000394011-0.11211-GBM
ENSG00000232533ENST00000429630MFSD6ENSG00000151690ENST00000412482-0.1069374CESCGBM
ENSG00000232533ENST00000429630CMTM4ENSG00000183723ENST00000394106-0.12081-GBM,KIRP,ESCA
ENSG00000232533ENST00000429630ITSN2ENSG00000198399ENST00000449392-0.142661-GBM
ENSG00000232533ENST00000429630HEATR5BENSG00000008869ENST00000425467-0.133519-GBM
ENSG00000232533ENST00000429630HACD3ENSG00000074696ENST00000565299-0.1601119-KIRP
ENSG00000232533ENST00000429630WDR7ENSG00000091157ENST00000589935-0.150565-GBM
ENSG00000232533ENST00000429630WDR7ENSG00000091157ENST00000591449-0.12991-GBM
ENSG00000232533ENST00000429630USP46ENSG00000109189ENST00000508499-0.2505541-GBM,KIRP
ENSG00000232533ENST00000429630USP46ENSG00000109189ENST00000512656-0.182087-GBM,KIRP
ENSG00000232533ENST00000429630LANCL1ENSG00000115365ENST00000453956-0.10911-GBM
ENSG00000232533ENST00000429630DNAJC16ENSG00000116138ENST00000472665-0.1518374-KIRP
ENSG00000232533ENST00000429630GCC2ENSG00000135968ENST00000614209-0.9017234-GBM
ENSG00000232533ENST00000429630KIAA1109ENSG00000138688ENST00000442707-0.3040358-GBM
ENSG00000232533ENST00000429630PDPK1ENSG00000140992ENST00000441549-0.125323-GBM
ENSG00000232533ENST00000429630PDPK1ENSG00000140992ENST00000492021-0.11611-GBM
ENSG00000232533ENST00000429630PDPK1ENSG00000140992ENST00000389224-0.204851-GBM
ENSG00000232533ENST00000429630KMT2DENSG00000167548ENST00000526209-0.1570125-GBM
ENSG00000232533ENST00000429630KIAA0232ENSG00000170871ENST00000508423-0.17508-GBM
ENSG00000232533ENST00000429630TTC3ENSG00000182670ENST00000540756-2.4750147-GBM
ENSG00000232533ENST00000429630TTC3ENSG00000182670ENST00000428693-0.3868249-GBM
ENSG00000232533ENST00000429630LYRM7ENSG00000186687ENST00000507584-0.104865-KIRP
ENSG00000232533ENST00000429630CIPCENSG00000198894ENST00000555437-0.151483-GBM,KIRP
ENSG00000232533ENST00000429630CIPCENSG00000198894ENST00000555611-0.145071-GBM,KIRP

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000232533.1ENST00000429630.1325103