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lncRNA: ENSG00000230937

Summary for MIR205HG

Gene summary

Gene information	Ensembl ID	ENSG00000230937
	Gene symbol	MIR205HG
	Gene name	MIR205 host gene
	HGNC	43562
	Entrez ID	642587
	Gene type	processed_transcript
	Synonyms	MIR205HG\|01q32.2
	UniProtAcc

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Structure and expression level for MIR205HG

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000230937	1.172034e+04	6.861187e+00	1.099417e+00	6.240750e+00	4.350000e-10	2.610000e-08	UP	CESC
ENSG00000230937	1.826419e+02	4.895301e+00	3.643990e-01	1.343391e+01	3.830000e-41	2.450000e-39	UP	UCEC
ENSG00000230937	1.550065e+03	-1.206479e+00	2.631289e-01	-4.585125e+00	4.540000e-06	1.760000e-05	DOWN	PRAD
ENSG00000230937	5.602711e+03	6.110222e+00	2.219608e-01	2.752838e+01	8.030000e-167	2.700000e-164	UP	LUSC
ENSG00000230937	1.735411e+03	-1.277323e+00	1.932809e-01	-6.608637e+00	3.880000e-11	1.550000e-10	DOWN	BRCA
ENSG00000230937	1.996202e+02	1.546840e+00	3.393051e-01	4.558846e+00	5.140000e-06	1.520000e-05	UP	LUAD

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000230937	-3.095795e-01	1.055462e-13	PRAD	5.956685e-13
ENSG00000230937	3.351296e-01	7.136304e-17	UCEC	1.232634e-15

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lncRNA-Protein interaction for MIR205HG

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000230937	ENST00000431096	MIR205HG	ENSG00000117595	IRF6	5.11	90.7085	O14896	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

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lncRNA-DNA interaction for MIR205HG

lncRNA targets the enhancer region and positively regulates the gene expression.

Only predicted by TDF

C16orf74,RAB38,SDC1,ARHGEF19,TNS4,S100A11,KRT15,RHOV,PHLDA3,PLP2,PRICKLE3,PERP,PPP1R13L,COL7A1,LAMB3,GJB5,KRT17,LAD1,KRT6A,ODF3B,S100A2,IRF6,TRIM29

Exist in public source

lncRNA targets the promoter region and positively regulates the gene expression.

Only predicted by TDF

IRF6,PKP1

Exist in public source

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for MIR205HG

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

TRAK2,RAPGEF2,SPATA13

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

ORF mutation

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000230937	ENST00000419143	exon_skip_71438	chr11:60941121-60941290	-19.29	-0.1198	SLC15A3	ENST00000227880	Frame-shift

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for MIR205HG

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID	PC Gene ID	PC Gene Name	Positive correlated cancers	Cancer with PC gene up-regulation	Cancer with PC gene down-regulation
ENSG00000230937	ENSG00000104140	RHOV	BLCA,CESC,ESCA,PRAD,TGCT,UCS	CESC
ENSG00000230937	ENSG00000104881	PPP1R13L	BLCA,CESC,ESCA,PRAD,TGCT,UCS	CESC
ENSG00000230937	ENSG00000131746	TNS4	BLCA,BRCA,PAAD,PRAD,TGCT,UCEC	UCEC	BRCA,PRAD
ENSG00000230937	ENSG00000189280	GJB5	BLCA,CESC,ESCA,HNSC,PRAD,TGCT,THYM	CESC	PRAD
ENSG00000230937	ENSG00000196754	S100A2	BLCA,CESC,ESCA,PRAD,TGCT,UCS	CESC	PRAD
ENSG00000230937	ENSG00000196878	LAMB3	BLCA,BRCA,ESCA,PRAD,TGCT,THYM,UCS		BRCA,PRAD
ENSG00000230937	ENSG00000205420	KRT6A	BLCA,CESC,ESCA,TGCT,UCS	CESC
ENSG00000230937	ENSG00000137699	TRIM29	BRCA,CESC,ESCA,PRAD,THYM,UCS	CESC	BRCA,PRAD
ENSG00000230937	ENSG00000112378	PERP	CESC,ESCA,TGCT,THYM,UCS	CESC
ENSG00000230937	ENSG00000159166	LAD1	CESC,ESCA,LUSC,TGCT,THYM	CESC,LUSC
ENSG00000230937	ENSG00000163191	S100A11	CESC,ESCA,HNSC,LUSC,TGCT	CESC,LUSC
ENSG00000230937	ENSG00000012211	PRICKLE3	ESCA,LUSC,PAAD,TGCT,THYM	LUSC
ENSG00000230937	ENSG00000114270	COL7A1	ESCA,LUSC,PAAD,PRAD,TGCT,THYM,UCS	LUSC
ENSG00000230937	ENSG00000115884	SDC1	ESCA,PRAD,TGCT,THYM,UCS		PRAD
ENSG00000230937	ENSG00000128422	KRT17	ESCA,LUAD,PAAD,PRAD,TGCT,UCS	LUAD
ENSG00000230937	ENSG00000154102	C16orf74	ESCA,HNSC,LUSC,PAAD,TGCT	LUSC

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID	LncRNA ENST ID	PC Gene Name	PC Gene ID	PC ENST ID	dG	nDG	Cancer with PC gene up-regulation	Cancer with PC gene Down-regulation
ENSG00000230937	ENST00000429156	RAPGEF2	ENSG00000109756	ENST00000512056	-0.1071	225	-	LUSC
ENSG00000230937	ENST00000429156	TRAK2	ENSG00000115993	ENST00000430254	-0.1047	550	-	LUSC
ENSG00000230937	ENST00000429156	SPATA13	ENSG00000182957	ENST00000399949	-0.1094	104	-	LUSC
ENSG00000230937	ENST00000433108	RAPGEF2	ENSG00000109756	ENST00000512056	-0.1034	1408	-	LUSC
ENSG00000230937	ENST00000603283	SPATA13	ENSG00000182957	ENST00000424834	-0.1704	1	-	LUSC
ENSG00000230937	ENST00000603283	SPATA13	ENSG00000182957	ENST00000382108	-0.1704	1	-	LUSC
ENSG00000230937	ENST00000603283	SPATA13	ENSG00000182957	ENST00000382095	-0.1704	1	-	LUSC
ENSG00000230937	ENST00000603283	SPATA13	ENSG00000182957	ENST00000343003	-0.1704	1	-	LUSC
ENSG00000230937	ENST00000603283	SPATA13	ENSG00000182957	ENST00000399949	-0.1704	1	-	LUSC
ENSG00000230937	ENST00000431096	RAPGEF2	ENSG00000109756	ENST00000512056	-0.1071	207	-	LUSC
ENSG00000230937	ENST00000431096	SPATA13	ENSG00000182957	ENST00000399949	-0.1048	86	-	LUSC
ENSG00000230937	ENST00000451937	SPATA13	ENSG00000182957	ENST00000399949	-0.1278	156	-	LUSC
ENSG00000230937	ENST00000366437	RAPGEF2	ENSG00000109756	ENST00000512056	-0.1071	34	-	LUSC
ENSG00000230937	ENST00000366437	SPATA13	ENSG00000182957	ENST00000424834	-0.1191	1	-	LUSC
ENSG00000230937	ENST00000366437	SPATA13	ENSG00000182957	ENST00000382108	-0.1191	1	-	LUSC
ENSG00000230937	ENST00000366437	SPATA13	ENSG00000182957	ENST00000382095	-0.1191	1	-	LUSC
ENSG00000230937	ENST00000366437	SPATA13	ENSG00000182957	ENST00000343003	-0.1191	1	-	LUSC
ENSG00000230937	ENST00000366437	SPATA13	ENSG00000182957	ENST00000399949	-0.1191	1	-	LUSC
ENSG00000230937	ENST00000444286	SPATA13	ENSG00000182957	ENST00000424834	-0.1543	1	-	LUSC
ENSG00000230937	ENST00000444286	SPATA13	ENSG00000182957	ENST00000382108	-0.1543	1	-	LUSC
ENSG00000230937	ENST00000444286	SPATA13	ENSG00000182957	ENST00000382095	-0.1543	1	-	LUSC
ENSG00000230937	ENST00000444286	SPATA13	ENSG00000182957	ENST00000434675	-0.1247	283	-	LUSC
ENSG00000230937	ENST00000444286	SPATA13	ENSG00000182957	ENST00000343003	-0.1543	1	-	LUSC
ENSG00000230937	ENST00000444286	SPATA13	ENSG00000182957	ENST00000399949	-0.1543	1	-	LUSC
ENSG00000230937	ENST00000458250	SPATA13	ENSG00000182957	ENST00000424834	-0.1172	1	-	LUSC
ENSG00000230937	ENST00000458250	SPATA13	ENSG00000182957	ENST00000382108	-0.1172	1	-	LUSC
ENSG00000230937	ENST00000458250	SPATA13	ENSG00000182957	ENST00000382095	-0.1172	1	-	LUSC
ENSG00000230937	ENST00000458250	SPATA13	ENSG00000182957	ENST00000434675	-0.1232	170	-	LUSC
ENSG00000230937	ENST00000458250	SPATA13	ENSG00000182957	ENST00000343003	-0.1172	1	-	LUSC
ENSG00000230937	ENST00000458250	SPATA13	ENSG00000182957	ENST00000399949	-0.1172	1	-	LUSC
ENSG00000230937	ENST00000458250	SPATA13	ENSG00000182957	ENST00000409126	-0.1232	170	-	LUSC

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000230937.8	ENST00000429156.4	78	241	5
ENSG00000230937.8	ENST00000433108.1	133	1	402
ENSG00000230937.8	ENST00000603283.4	148	1984	2430
ENSG00000230937.8	ENST00000431096.4	80	431	189
ENSG00000230937.8	ENST00000451937.4	126	4	384
ENSG00000230937.8	ENST00000366437.6	95	167	454
ENSG00000230937.8	ENST00000444286.1	102	195	503
ENSG00000230937.8	ENST00000458250.4	90	513	241
ENSG00000230937.8	ENST00000419143.1	78	64	300
ENSG00000230937.8	ENST00000440276.2	148	488	934

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential