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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000230838

Summary for LINC01614

check button Gene summary

Gene informationEnsembl ID

ENSG00000230838

Gene symbol

LINC01614

Gene namelong intergenic non-protein coding RNA 1614
HGNC

51847

Entrez ID
Gene typelincRNA
SynonymsLINC01614|AC093850.2|02q35
UniProtAcc

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Structure and expression level for LINC01614

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002308382.568873e+012.732810e+008.285163e-013.298438e+009.722420e-043.681671e-03UPGBM
ENSG000002308386.070035e+012.824231e+005.951802e-014.745171e+002.080000e-061.720000e-05UPBLCA
ENSG000002308386.946729e+015.885741e+003.940327e-011.493719e+011.890000e-507.140000e-48UPHNSC
ENSG000002308386.856929e+014.194045e+006.855261e-016.117994e+009.480000e-106.560000e-08UPESCA
ENSG000002308381.070361e+022.831533e+002.438363e-011.161243e+013.560000e-314.030000e-30UPLUSC
ENSG000002308383.045961e+025.550443e+001.530433e-013.626714e+015.340000e-2884.140000e-284UPBRCA
ENSG000002308388.458277e+013.649093e+002.361215e-011.545430e+017.060000e-544.730000e-52UPLUAD
ENSG000002308385.689082e+014.735036e+004.093590e-011.156695e+016.060000e-312.000000e-28UPSTAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002308383.751745e-017.469245e-16BLCA2.188489e-13
ENSG000002308383.203643e-017.186267e-13HNSC1.145901e-10

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lncRNA-Protein interaction for LINC01614

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for LINC01614

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for LINC01614

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000230838ENST00000415479exon_skip_24067chr1:31679803-31679851-9.39-0.2471COL16A1ENST00000373672In-frame
ENSG00000230838ENST00000415479exon_skip_21610chr1:9737497-9737554-7.85-0.1707CLSTN1ENST00000377298In-frame
ENSG00000230838ENST00000415479exon_skip_287874chr17:29085603-29085648-6.21-0.1941MYO18AENST00000527372In-frame
ENSG00000230838ENST00000415479exon_skip_376144chr3:100311832-100311877-6.39-0.1521TBC1D23ENST00000394144In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000230838ENST00000415479exon_skip_24063chr1:31670601-31670646-7.77-0.1992COL16A1ENST00000373672In-frame
ENSG00000230838ENST00000415479exon_skip_37489chr1:225517195-225517306-12.83-0.1309ENAHENST00000366844In-frame
ENSG00000230838ENST00000415479exon_skip_384879chr3:52554723-52554879-17.09-0.1155PBRM1ENST00000296302In-frame
ENSG00000230838ENST00000415479exon_skip_434332chr5:34813573-34813660-10.70-0.1305RAI14ENST00000265109,ENST00000428746,ENST00000503673In-frame
ENSG00000230838ENST00000415479exon_skip_456460chr6:17771113-17771218-13.14-0.4380KIF13AENST00000259711In-frame
ENSG00000230838ENST00000415479exon_skip_461111chr6:90544551-90544632-8.03-0.1275MAP3K7ENST00000369329In-frame
ENSG00000230838ENST00000415479exon_skip_48713chr10:34336198-34336243-9.50-0.2879PARD3ENST00000374789In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for LINC01614

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000230838.1ENST00000415479.166360557