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lncRNA: ENSG00000230487

Summary for PSMG3-AS1

Gene summary

Gene information	Ensembl ID	ENSG00000230487
	Gene symbol	PSMG3-AS1
	Gene name	PSMG3 antisense RNA 1 (head to head)
	HGNC	22230
	Entrez ID	114796
	Gene type	lincRNA
	Synonyms	07p22.3\|PSMG3-AS1
	UniProtAcc	Q96PY0

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Structure and expression level for PSMG3-AS1

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000230487	3.968805e+02	-1.268988e+00	7.784188e-02	-1.630212e+01	9.530000e-60	3.290000e-58	DOWN	KIRC
ENSG00000230487	5.112975e+02	-1.390602e+00	1.507490e-01	-9.224617e+00	2.850000e-20	4.740000e-19	DOWN	KICH

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000230487	4.210660e-01	3.972290e-03	CHOL	5.353679e-03
ENSG00000230487	-5.458641e-01	3.159004e-08	KICH	1.414532e-07
ENSG00000230487	-4.109673e-01	3.541184e-26	KIRC	7.967665e-25

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lncRNA-Protein interaction for PSMG3-AS1

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000263001	GTF2I	22.28	91.804	P78347	TF,Epi	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000116539	ASH1L	108.26	93.366	Q9NR48	TF,Epi	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000116539	ASH1L	68.57	96.6955	Q9NR48	TF,Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000126705	AHDC1	109.85	97.5504	Q5TGY3	TF	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000146587	RBAK	109.43	96.9525	Q9NYW8	TF	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000116539	ASH1L	108.26	93.3155	Q9NR48	TF,Epi	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000180787	ZFP3	98.21	92.0593	Q96NJ6	TF	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000184481	FOXO4	97.25	91.4553	P98177	TF	ChIP-seq
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000136451	VEZF1	89.28	94.7153	Q14119	TF	ChIP-seq
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000164631	ZNF12	85.05	96.4083	P17014	TF	ChIP-seq
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000106459	NRF1	73.18	93.5234	Q16656	TF	ChIP-seq
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000146587	RBAK	71.37	95.0718	Q9NYW8	TF	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000154957	ZNF18	69.06	96.3883	P17022	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000116539	ASH1L	68.57	96.5818	Q9NR48	TF,Epi	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000148411	NACC2	67.17	96.3103	Q96BF6	TF	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000184939	ZFP90	65.83	96.8316	Q8TF47	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000126705	AHDC1	63.11	95.6633	Q5TGY3	TF	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000196152	ZNF79	58.41	97.1637	Q15937	TF	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000136936	XPA	57.28	92.7757	P23025	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000164631	ZNF12	56.89	94.8491	P17014	TF	ChIP-seq
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000198517	MAFK	55.87	90.9312	O60675	TF	ChIP-seq
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000165821	SALL2	55.67	91.6989	Q9Y467	TF	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000141646	SMAD4	54.69	95.695	Q13485	TF	ChIP-seq
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000175395	ZNF25	53.05	97.3658	P17030	TF	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000065029	ZNF76	50.8	97.1481	P36508	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000180787	ZFP3	45.31	94.4635	Q96NJ6	TF	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000275111	ZNF2	45.17	97.014	Q9BSG1	TF	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000187792	ZNF70	41.89	97.2279	Q9UC06	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000148411	NACC2	40.55	93.1743	Q96BF6	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000136451	VEZF1	40.28	91.7214	Q14119	TF	ChIP-seq
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000174282	ZBTB4	37.58	95.0424	Q9P1Z0	TF	ChIP-seq
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000184939	ZFP90	37.24	95.3656	Q8TF47	TF	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000146587	RBAK	33.94	93.3418	Q9NYW8	TF	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000114126	TFDP2	32.57	97.1291	Q14188	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000070476	ZXDC	31.73	91.5335	Q2QGD7	TF	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000184939	ZFP90	29.82	91.6706	Q8TF47	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000077092	RARB	27.15	92.1949	P10826	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000154957	ZNF18	25.91	94.2087	P17022	TF	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000065029	ZNF76	25.87	90.6412	P36508	TF	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000126705	AHDC1	25.41	91.4048	Q5TGY3	TF	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000164631	ZNF12	25.23	91.5969	P17014	TF	ChIP-seq
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000065029	ZNF76	24.56	94.8736	P36508	TF	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000154957	ZNF18	20.34	93.162	P17022	TF	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000174282	ZBTB4	19.94	94.1945	Q9P1Z0	TF	ChIP-seq
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000166432	ZMAT1	19.9	92.0482	Q5H9K5	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000196152	ZNF79	18.03	95.0249	Q15937	TF	NA
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000077092	RARB	17.63	94.9143	P10826	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000187792	ZNF70	16.29	95.1671	Q9UC06	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000175395	ZNF25	14.53	95.1665	P17030	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000275111	ZNF2	11.66	94.6338	Q9BSG1	TF	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000114126	TFDP2	11.11	94.0027	Q14188	TF	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000196152	ZNF79	10.89	91.2545	Q15937	TF	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000175395	ZNF25	9.89	91.1754	P17030	TF	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000070476	ZXDC	8.34	91.8295	Q2QGD7	TF	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000275111	ZNF2	6.29	92.2504	Q9BSG1	TF	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000114126	TFDP2	5.46	93.0416	Q14188	TF	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000077092	RARB	0.68	90.1872	P10826	TF	NA
ENSG00000230487	ENST00000612019	PSMG3-AS1	ENSG00000116539	ASH1L	18.5	90.4195	Q9NR48	TF,Epi	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000230487	ENST00000437621	PSMG3-AS1	ENSG00000127993	RBM48	77.75	95.5401	Q5RL73	RBP	NA
ENSG00000230487	ENST00000457484	PSMG3-AS1	ENSG00000163728	TTC14	31.37	92.8753	Q96N46	RBP	NA
ENSG00000230487	ENST00000437964	PSMG3-AS1	ENSG00000198231	DDX42	22.85	93.7698	Q86XP3	RBP	NA

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lncRNA-DNA interaction for PSMG3-AS1

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for PSMG3-AS1

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

SLIRP

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000230487	ENST00000524978	exon_skip_27065	chr1:52906518-52906611	-13.58	-0.2190	ECHDC2	ENST00000371522	In-frame
ENSG00000230487	ENST00000524978	exon_skip_67681	chr11:893426-893519	-16.45	-0.1808	CHID1	ENST00000323578,ENST00000436108,ENST00000449825	In-frame
ENSG00000230487	ENST00000524978	exon_skip_509230	chrX:13763744-13763855	-18.60	-0.1771	OFD1	ENST00000340096	In-frame

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000230487	ENST00000524978	exon_skip_368399	chr22:29825621-29825780	-21.27	-0.1363	ASCC2	ENST00000307790,ENST00000397771	In-frame

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for PSMG3-AS1

RNA A-to-I editing events in lncRNA.

LncRNAediting ID	LncRNA Ensembl ID	Chromosome	Editing Position	Strand	Gene Type	Gene Name	Transcript ID	Transcript Type	Transcript Name
LncEditing_176242	ENSG00000230487.6	chr7	1579336	+	lincRNA	PSMG3-AS1	ENST00000612019.1	lincRNA	PSMG3-AS1-011

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID	LncRNA Index	Cancer Type	Chr_Postion_Strand	AVE1	AVE2	log2FC	W-value	P-value	Adjc.p-value	Change
ENSG00000230487	LncEditing_176242	GBM	chr7_1579336_+	4.625692e+00	3.331979e+00	2.112870e+00	2.422157e+00	1.542870e-02	1.644508e-02	UP
ENSG00000230487	LncEditing_176242	LGG	chr7_1579336_+	4.941209e+00	3.523016e+00	2.048957e+00	7.634928e+00	2.259465e-14	4.406582e-14	UP
ENSG00000230487	LncEditing_176242	PCPG	chr7_1579336_+	4.356885e+00	2.605162e+00	1.347847e+00	4.630741e+00	3.643595e-06	7.026933e-06	UP

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID	LncRNA Index	Correlation	P-value	Adjc.p-value
ENSG00000230487	LncEditing_176242	-4.148398e-01	2.910499e-04	4.304259e-04

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000230487.6	ENST00000437621.5	74	18	239
ENSG00000230487.6	ENST00000457484.5	352	3014	4072
ENSG00000230487.6	ENST00000437964.4	211	2181	1546
ENSG00000230487.6	ENST00000533935.4	320	2566	1604
ENSG00000230487.6	ENST00000532358.4	92	482	204
ENSG00000230487.6	ENST00000612019.1	92	478	200
ENSG00000230487.6	ENST00000524978.2	59	108	287

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential