 lncRNA targets the enhancer region and positively regulates the gene expression. |
| lncRNA targets the promoter region and positively regulates the gene expression. |
| lncRNA targets the promoter region and negatively regulates the gene expression. |
| lncRNA targets the 3'UTR region and negatively regulates the mRNA. |
| lncRNA targets the skipped exon region. | | -lncRNA and exonskipping events are positively correlated. |
| LncRNA Ensembl ID | LncRNA ENST ID | Exon ID | Skipped Exon | dG | ndG | Gene name with skipped exon | TransID with skipped exon | ORF mutation |
| -lncRNA and exonskipping events are negatively correlated. |
| LncRNA Ensembl ID | LncRNA ENST ID | Exon ID | Skipped Exon | dG | ndG | Gene name with skipped exon | TransID with skipped exon | LOF | | ENSG00000230415 | ENST00000453732 | exon_skip_382458 | chr3:38131595-38131638 | -10.45 | -0.2488 | ACAA1 | ENST00000333167 | Frame-shift |
| lncRNA targets by miRNA. |
| LncRNA Ensembl ID | miRNA ID | LncRNA ENST ID | Binding site in lncRNA | Score | Energy | Align Len | Public source | | ENSG00000230415 | hsa-mir-22 | ENST00000434139 | chr1:1275282-1275368 | 166.00 | -87.07 | 81 | NA | | ENSG00000230415 | hsa-mir-22 | ENST00000434139 | chr1:1275381-1275472 | 143.00 | -84.60 | 84 | NA | | ENSG00000230415 | hsa-mir-22 | ENST00000453732 | chr1:1275341-1275429 | 169.00 | -87.95 | 88 | NA | | ENSG00000230415 | hsa-mir-22 | ENST00000453732 | chr1:1275449-1275532 | 147.00 | -82.95 | 78 | NA | | ENSG00000230415 | hsa-mir-22 | ENST00000453732 | chr1:1275258-1275347 | 146.00 | -90.58 | 86 | NA |
| RNA A-to-I editing events in lncRNA. |
| LncRNAediting ID | LncRNA Ensembl ID | Chromosome | Editing Position | Strand | Gene Type | Gene Name | Transcript ID | Transcript Type | Transcript Name | | LncEditing_216 | ENSG00000230415.1 | chr1 | 1280065 | + | lincRNA | RP5-902P8.10 | ENST00000434139.1 | lincRNA | RP5-902P8.10-001 | | LncEditing_217 | ENSG00000230415.1 | chr1 | 1280071 | + | lincRNA | RP5-902P8.10 | ENST00000434139.1 | lincRNA | RP5-902P8.10-001 | | LncEditing_219 | ENSG00000230415.1 | chr1 | 1280098 | + | lincRNA | RP5-902P8.10 | ENST00000434139.1 | lincRNA | RP5-902P8.10-001 |
| Edited-associated DElncRNAs in cancer. |
| LncRNA Ensembl ID | LncRNA Index | Cancer Type | Chr_Postion_Strand | AVE1 | AVE2 | log2FC | W-value | P-value | Adjc.p-value | Change | | ENSG00000230415 | LncEditing_217 | GBM | chr1_1280071_+ | 3.851617e+00 | 1.688470e+00 | 8.405144e-01 | 6.283714e+00 | 3.305790e-10 | 1.310973e-09 | UP | | ENSG00000230415 | LncEditing_217 | LGG | chr1_1280071_+ | 5.706986e+00 | 2.792804e+00 | 9.699182e-01 | 9.784445e+00 | 1.313132e-22 | 4.754211e-22 | UP | | ENSG00000230415 | LncEditing_216 | THYM | chr1_1280065_+ | 2.289771e+00 | 1.585848e+00 | 1.886974e+00 | 3.532025e+00 | 4.123901e-04 | 6.260936e-04 | UP | | ENSG00000230415 | LncEditing_219 | OV | chr1_1280098_+ | 2.779067e+00 | 1.175073e+00 | 8.052499e-01 | 7.817221e+00 | 5.400219e-15 | 1.495633e-14 | UP |
| Correlation between RNA A-to-I editing events's frequecy and lncRNA expression. |
| LncRNA Ensembl ID | LncRNA Index | Correlation | P-value | Adjc.p-value | | ENSG00000230415 | LncEditing_216 | -4.702158e-01 | 5.399766e-07 | 1.181791e-05 | | ENSG00000230415 | LncEditing_219 | -5.254772e-01 | 3.797769e-05 | 2.197642e-04 | | ENSG00000230415 | LncEditing_217 | -3.395150e-01 | 2.063139e-03 | 2.393697e-03 |
| Cis-expression quantitative trait loci(cis-eQTL) of lncRNA. |
| LncRNA Ensembl ID | LncRNA Name | SNP info | Number of Positive corelated Cancer | Positive corelated Cancer | Number of Negative corelated Cancer | Negative corelated Cancer |
| lncRNA regulates differentially expressed genes by function as enhancer. |
| LncRNA Ensembl ID | PC Gene ID | PC Gene Name | Positive correlated cancers | Cancer with PC gene up-regulation | Cancer with PC gene down-regulation |
| LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5). |
| lncRNA ID | TF ID | TF Name | PCgene ID | PCgene Name | Number of Cancer | Canaer Types |
| LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5). |
| lncRNA ID | TF ID | TF Name | PCgene ID | PCgene Name | Number of Cancer | Canaer Types |
| LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region. |
| LncRNA Ensembl ID | RBP ID | RBP Gene Name | Exon Skipping ID | Skipped Exon | EX Gene Name | EX Affected TransID | ORF_anno | Cancer Type |
| LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region. |
| LncRNA Ensembl ID | RBP ID | RBP Gene Name | Exon Skipping ID | Skipped Exon | EX Gene Name | EX Affected TransID | ORF_anno | Cancer Type |
| lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region. |
| LncRNA Ensembl ID | LncRNA ENST ID | PC Gene Name | PC Gene ID | PC ENST ID | dG | nDG | Cancer with PC gene up-regulation | Cancer with PC gene Down-regulation |
| lncRNA regulates mRNA by competing the miRNA binding site with mRNA. |
| LncRNA Ensembl ID | lncRNA-miRNA-mRNA | Cancer Types | | ENSG00000230415 | LINC01786,hsa-mir-22,CRMP1 | PCPG,LGG,MESO,SARC,KIRP | | ENSG00000230415 | LINC01786,hsa-mir-22,PHC1 | PCPG,LGG,MESO,SARC,KIRP | | ENSG00000230415 | LINC01786,hsa-mir-22,TNRC18 | PCPG,LGG,MESO,SARC,KIRP | | ENSG00000230415 | LINC01786,hsa-mir-22,EDRF1 | PCPG,LGG,MESO,SARC,KIRP | | ENSG00000230415 | LINC01786,hsa-mir-22,SBK1 | PCPG,LGG,MESO,SARC,KIRP | | ENSG00000230415 | LINC01786,hsa-mir-22,FBXO46 | PCPG,LGG,MESO,SARC,KIRP | | ENSG00000230415 | LINC01786,hsa-mir-22,DGCR8 | PCPG,LGG,MESO,SARC,KIRP | | ENSG00000230415 | LINC01786,hsa-mir-22,ILF3 | PCPG,LGG,MESO,SARC,KIRP | | ENSG00000230415 | LINC01786,hsa-mir-22,EDC3 | PCPG,LGG,MESO,SARC,KIRP |
| ORFfinder result for the gencode.v22.lncRNA.transcript.fa. |
| lncRNA Ensembl ID | lncRNA ENST ID | length(AA) | start at transcript | end at transcript | | ENSG00000230415.1 | ENST00000434139.1 | 121 | 395 | 30 | | ENSG00000230415.1 | ENST00000453732.1 | 44 | 31 | 165 |
|
